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Search results 301 to 394 out of 394 for Npr2

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Type Details Score
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
34083520 | J:333259
First Author: Yuan F
Year: 2021
Journal: Cell Death Dis
Title: Sgpl1 deletion elevates S1P levels, contributing to NPR2 inactivity and p21 expression that block germ cell development.
Volume: 12
Issue: 6
Pages: 574
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Publication
34838130 | J:315150
First Author: Sogawa-Fujiwara C
Year: 2021
Journal: BMC Res Notes
Title: Npr2 mutant mice show vasodilation and undeveloped adipocytes in mesentery.
Volume: 14
Issue: 1
Pages: 438
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Protein Coding Gene
MGI:1914482 | Nprl2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29768191 | J:271536
First Author: Dutchak PA
Year: 2018
Journal: Cell Rep
Title: Loss of a Negative Regulator of mTORC1 Induces Aerobic Glycolysis and Altered Fiber Composition in Skeletal Muscle.
Volume: 23
Issue: 7
Pages: 1907-1914
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Gene
379794 | nprl2.S
Type: gene
Organism: frog, African clawed
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Publication
35602938 | J:325053
First Author: Dentel B
Year: 2022
Journal: iScience
Title: Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model.
Volume: 25
Issue: 5
Pages: 104334
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Allele
Nprl2<+> | MGI:3050000
   
Name: NPR2 like, GATOR1 complex subunit; wild type
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Publication
35165201 | J:333548
 
First Author: Hui JB
Year: 2022
Journal: eNeuro
Title: NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis.
Volume: 9
Issue: 2
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Protein Coding Gene
MGP_CAROLIEiJ_G0032646 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035143 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035769 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015514 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033791 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7435364
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:7435390
Age: embryonic day 12.5
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7435364
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:7435390
Age: embryonic day 12.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7435364
Assay Type: RT-PCR
Annotation Date: 2023-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:7435390
Age: embryonic day 12.5
Image: 1
Specimen Label: KO
Detected: false
Specimen Num: 3
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Allele
Nprl2<Gt(OST193486)Lex> | MGI:4225069
 
Name: NPR2 like, GATOR1 complex subunit; gene trap OST193486, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Nprl2<tm1(KOMP)Vlcg> | MGI:4452978
Name: NPR2 like, GATOR1 complex subunit; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Nprl2<em1Saei> | MGI:7327417
Name: NPR2 like, GATOR1 complex subunit; endonuclease-mediated mutation 1, Saeko Ishida
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Nprl2<em1Cya> | MGI:7585405
Name: NPR2 like, GATOR1 complex subunit; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Nprl2<em2Cya> | MGI:7585406
Name: NPR2 like, GATOR1 complex subunit; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
34965576 | J:326754
First Author: Ishida S
Year: 2022
Journal: Hum Mol Genet
Title: Dorsal telencephalon-specific Nprl2- and Nprl3-knockout mice: novel mouse models for GATORopathy.
Volume: 31
Issue: 9
Pages: 1519-1530
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Allele
Nprl2<Gt(IST12879B12)Tigm> | MGI:4098814
 
Name: NPR2 like, GATOR1 complex subunit; gene trap IST12879B12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Nprl2<tm1(KOMP)Wtsi> | MGI:4419370
Name: NPR2 like, GATOR1 complex subunit; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:5603847 | C57BL/6N-Nprl2<tm1(KOMP)Vlcg>/J
Attribute String: mutant strain, targeted mutation
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Allele
Nprl2<em1Smoc> | MGI:7265145
Name: NPR2 like, GATOR1 complex subunit; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Nprl2<tm1.1Bpt> | MGI:5792911
Name: NPR2 like, GATOR1 complex subunit; targeted mutation 1.1, Benjamine P Tu
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Nprl2<tm1.2Bpt> | MGI:5792912
Name: NPR2 like, GATOR1 complex subunit; targeted mutation 1.2, Benjamine P Tu
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nprl2<em2Smoc> | MGI:7291374
Name: NPR2 like, GATOR1 complex subunit; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7592307 | C57BL/6J-Nprl2<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7589791 | C57BL/6J-Nprl2<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Npr2<slw> | MGI:3774275
 
Name: natriuretic peptide receptor 2; short-limbed dwarfism
Allele Type: Spontaneous
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Allele
Npr2<pwe> | MGI:4358115
 
Name: natriuretic peptide receptor 2; peewee
Allele Type: Spontaneous
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Publication
26166573 | J:224837
First Author: Dutchak PA
Year: 2015
Journal: Cell Rep
Title: Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2.
Volume: 12
Issue: 3
Pages: 371-9
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Strain
MGI:6766731 | C57BL/6N-Nprl2<tm1(KOMP)Wtsi>/Cmsu
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:6771000 | C57BL/6JSmoc-Nprl2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7718172 | C57BL/6JSmoc-Nprl2<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Nprl2/Nprl2
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Allele
Tg(Col11a2-Npr2*)28Keoz | MGI:5448404
Name: transgene insertion 28, Keiichi Ozono
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Npr2/Npr2
Background: involves: C57BL/6 * DDY
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Npr2/Npr2
Background: involves: C3H/HeJ * C57BL/6 * NAW/WI
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0080050 | acromesomelic dysplasia, Maroteaux type
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DO Term
DOID:0070316 | Miura type epiphyseal chondrodysplasia
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Publication
22870295 | J:189658
First Author: Miura K
Year: 2012
Journal: PLoS One
Title: An overgrowth disorder associated with excessive production of cGMP due to a gain-of-function mutation of the natriuretic peptide receptor 2 gene.
Volume: 7
Issue: 8
Pages: e42180
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Genotype
Genotype
Symbol: Nprl2/Nprl2<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Publication
30544148 | J:272979
First Author: Yamamoto K
Year: 2019
Journal: Hum Mol Genet
Title: CREB activation in hypertrophic chondrocytes is involved in the skeletal overgrowth in epiphyseal chondrodysplasia Miura type caused by activating mutations of natriuretic peptide receptor B.
Volume: 28
Issue: 7
Pages: 1183-1198
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Allele
Npr2<tm1Fgr> | MGI:5567993
Name: natriuretic peptide receptor 2; targeted mutation 1, Fritz G Rathjen
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Npr2<tm2.1(cre/ERT2)Fgr> | MGI:5567995
Name: natriuretic peptide receptor 2; targeted mutation 2.1, Fritz G Rathjen
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Genotype
Genotype
Symbol: Tg(Col11a2-Npr2*)28Keoz/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Publication
36528027 | J:332370
First Author: Jiang C
Year: 2023
Journal: Mol Cell
Title: Ring domains are essential for GATOR2-dependent mTORC1 activation.
Volume: 83
Issue: 1
Pages: 74-89.e9
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Allele
Npr2<tm1.1Laj> | MGI:5911053
 
Name: natriuretic peptide receptor 2; targeted mutation 1.1, Laurinda A Jaffe
Allele Type: Targeted
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Allele
Npr2<tm1.2Laj> | MGI:7482668
Name: natriuretic peptide receptor 2; targeted mutation 1.2, Laurinda A Jaffe
Allele Type: Targeted
Attribute String: Conditional ready
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Genotype
Genotype
Symbol: Npr2/Npr2
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Publication
11085536 | J:66052
First Author: Lerman MI
Year: 2000
Journal: Cancer Res
Title: The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
Volume: 60
Issue: 21
Pages: 6116-33
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Strain
MGI:7482665 | B6;129S-Npr2<tm1.1Laj>/Mmjax
Attribute String: mutant stock, targeted mutation
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Strain
MGI:7482669 | B6;129S-Npr2<tm1.2Laj>/Mmjax
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Npr2/Npr2 Tg(CAG-Bgeo/ALPP)1Lbe/?
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * AKR/J * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
23592428 | J:302715
First Author: Yu C
Year: 2013
Journal: Mol Endocrinol
Title: Selective Smad4 knockout in ovarian preovulatory follicles results in multiple defects in ovulation.
Volume: 27
Issue: 6
Pages: 966-78
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Publication
24804968 | J:212921
First Author: Richard S
Year: 2014
Journal: Biol Reprod
Title: Prophase I arrest of mouse oocytes mediated by natriuretic peptide precursor C requires GJA1 (connexin-43) and GJA4 (connexin-37) gap junctions in the antral follicle and cumulus-oocyte complex.
Volume: 90
Issue: 6
Pages: 137
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Publication
27335069 | J:236484
First Author: Hao X
Year: 2016
Journal: Biol Reprod
Title: Epidermal Growth Factor-Mobilized Intracellular Calcium of Cumulus Cells Decreases Natriuretic Peptide Receptor 2 Affinity for Natriuretic Peptide Type C and Induces Oocyte Meiotic Resumption in the Mouse.
Volume: 95
Issue: 2
Pages: 45
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Publication
35287796 | J:321972
   
First Author: Miyazaki Y
Year: 2022
Journal: Elife
Title: C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth.
Volume: 11
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Publication
27959934 | J:243806
First Author: Esapa CT
Year: 2016
Journal: PLoS One
Title: Mice with an N-Ethyl-N-Nitrosourea (ENU) Induced Tyr209Asn Mutation in Natriuretic Peptide Receptor 3 (NPR3) Provide a Model for Kyphosis Associated with Activation of the MAPK Signaling Pathway.
Volume: 11
Issue: 12
Pages: e0167916
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Publication
15073147 | J:89363
First Author: Zelzer E
Year: 2004
Journal: Development
Title: VEGFA is necessary for chondrocyte survival during bone development.
Volume: 131
Issue: 9
Pages: 2161-71
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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