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Search results 301 to 364 out of 364 for Nrf1

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Type Details Score
Protein Domain
IPR033361 | RETREG3
Type: Family
Description: Reticulophagy regulator 3 (RETREG3), also known as FAM134C, mediates NRF1-enhanced neurite outgrowth. NRF1 (nuclear respiratory factor-1) is a major transcription factor that can positively regulate FAM134C []. Members of the FAM134 protein family, including FAM134C, are ER-resident receptors that bind to autophagy modifiers LC3 and GABARAP, and facilitate ER degradation by autophagy [].
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Protein Domain
IPR025999 | MCRS_N
Type: Domain
Description: This domain is found in plants and higher eukaryotes, and is the N-terminal region of micro-spherule proteins which repress the transactivation activities of Nrf1 (p45 nuclear factor-erythroid 2 (p45 NF-E2)-related factor 1) []. In conjunction with DIPA the full-length protein acts as a transcription repressor []. The exact function of this domain is not known.
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Publication
26040720 | J:222922
First Author: Khaminets A
Year: 2015
Journal: Nature
Title: Regulation of endoplasmic reticulum turnover by selective autophagy.
Volume: 522
Issue: 7556
Pages: 354-8
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Protein
Q9CQV4
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: false
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Publication
23939472 | -
First Author: Wang JL
Year: 2013
Journal: Gene
Title: Novel genes FAM134C, C3orf10 and ENOX1 are regulated by NRF-1 and differentially regulate neurite outgrowth in neuroblastoma cells and hippocampal neurons.
Volume: 529
Issue: 1
Pages: 7-15
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Publication
25792330 | J:221607
First Author: Mohrin M
Year: 2015
Journal: Science
Title: Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging.
Volume: 347
Issue: 6228
Pages: 1374-7
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Protein Domain
IPR043384 | RETREG1/3
Type: Family
Description: This entry include reticulophagy receptor 1 and reticulophagy receptor 3.Reticulophagy receptor 1, previously known as FAM134B, is essential for endoplasmic reticulum (ER) homeostasis. It is a ER resident receptor that binds to autophagy modifiers LC3 and GABARAP, and facilitates ER degradation by autophagy. It may promote membrane remodelling and ER scission via the membrane-bending capacity of its reticulon domain, whereas its LIR motif may be necessary to target the ER fragments to autophagosomes for lysosomal degradation [].Reticulophagy regulator 3 (RETREG3), also known as FAM134C, mediates NRF1-enhanced neurite outgrowth. NRF1 (nuclear respiratory factor-1) is a major transcription factor that can positively regulate FAM134C []. Members of the FAM134 protein family, including FAM134C, are ER-resident receptors that bind to autophagy modifiers LC3 and GABARAP, and facilitate ER degradation by autophagy [].
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Protein
Q3U4L3
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
Q3U5L0
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
Q3V3M1
Organism: Mus musculus/domesticus
Length: 453  
Fragment?: false
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Protein
Q6KAM4
Organism: Mus musculus/domesticus
Length: 767  
Fragment?: true
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Protein
Q9CW60
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: true
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Protein
A2A6D2
Organism: Mus musculus/domesticus
Length: 742  
Fragment?: false
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Protein
Q3UFI8
Organism: Mus musculus/domesticus
Length: 572  
Fragment?: false
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Protein
Q6GTN8
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Publication
21953459 | J:252001
First Author: Biswas M
Year: 2011
Journal: J Biol Chem
Title: The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
Volume: 286
Issue: 45
Pages: 39282-9
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Publication
20816089 | J:166368
First Author: Kim HS
Year: 2010
Journal: Cell Metab
Title: Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis.
Volume: 12
Issue: 3
Pages: 224-36
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Publication
24395638 | J:208269
First Author: Zambrano A
Year: 2014
Journal: J Cell Biol
Title: The thyroid hormone receptor β induces DNA damage and premature senescence.
Volume: 204
Issue: 1
Pages: 129-46
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Publication
20300111 | J:175212
First Author: Meixner A
Year: 2010
Journal: Cell Death Differ
Title: Jun and JunD-dependent functions in cell proliferation and stress response.
Volume: 17
Issue: 9
Pages: 1409-19
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Publication
27760309 | J:240758
First Author: Duteil D
Year: 2016
Journal: Cell Rep
Title: Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.
Volume: 17
Issue: 4
Pages: 1008-1021
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Publication
34838815 | J:322461
 
First Author: Li T
Year: 2022
Journal: Neuropharmacology
Title: Mitochondriomics reveals the underlying neuroprotective mechanism of TrkB receptor agonist R13 in the 5×FAD mice.
Volume: 204
Pages: 108899
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Publication
25637874 | J:220017
First Author: Ho DV
Year: 2015
Journal: FEBS Lett
Title: Induction of Herpud1 expression by ER stress is regulated by Nrf1.
Volume: 589
Issue: 5
Pages: 615-20
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Publication
22971132 | J:203246
First Author: Oh DH
Year: 2012
Journal: FEBS J
Title: Deficiency in the nuclear-related factor erythroid 2 transcription factor (Nrf1) leads to genetic instability.
Volume: 279
Issue: 22
Pages: 4121-30
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Publication
26849429 | J:249029
First Author: Shen L
Year: 2016
Journal: PLoS One
Title: MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes.
Volume: 11
Issue: 2
Pages: e0148532
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Protein
Q8VE91
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
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Protein
A0A2I3BR09
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: true
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Protein
A0A2R8VJX8
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
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Protein
A0A2I3BS06
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: true
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Protein
A0A2I3BQZ7
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
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Publication
10037736 | J:53336
First Author: Kobayashi A
Year: 1999
Journal: J Biol Chem
Title: Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.
Volume: 274
Issue: 10
Pages: 6443-52
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Publication
31026811 | J:289184
First Author: Yang W
Year: 2019
Journal: J Endocrinol
Title: Glucagon regulates hepatic mitochondrial function and biogenesis through FOXO1.
Volume: 241
Issue: 3
Pages: 265-278
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Publication
29400713 | J:265034
First Author: Bartelt A
Year: 2018
Journal: Nat Med
Title: Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.
Volume: 24
Issue: 3
Pages: 292-303
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Publication
17179207 | J:117460
First Author: Suliman HB
Year: 2007
Journal: J Cell Sci
Title: A new activating role for CO in cardiac mitochondrial biogenesis.
Volume: 120
Issue: Pt 2
Pages: 299-308
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Publication
32084533 | J:311344
 
First Author: Singulani MP
Year: 2020
Journal: Exp Gerontol
Title: Impairment of PGC-1α-mediated mitochondrial biogenesis precedes mitochondrial dysfunction and Alzheimer's pathology in the 3xTg mouse model of Alzheimer's disease.
Volume: 133
Pages: 110882
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Publication
31137011 | J:294405
First Author: Rajasekaran M
Year: 2019
Journal: J Endocrinol
Title: MCP-1 deficiency enhances browning of adipose tissue via increased M2 polarization.
Volume: 242
Issue: 2
Pages: 91-101
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Publication
38051904 | J:357482
First Author: Li B
Year: 2024
Journal: Neural Regen Res
Title: Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease.
Volume: 19
Issue: 7
Pages: 1593-1601
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Publication
29125827 | J:250109
First Author: Lin H
Year: 2017
Journal: Dis Model Mech
Title: Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia.
Volume: 10
Issue: 11
Pages: 1343-1352
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Publication
11118612 | J:66528
First Author: Chan JY
Year: 2000
Journal: Biochim Biophys Acta
Title: Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein.
Volume: 1517
Issue: 1
Pages: 19-26
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Publication
23702335 | J:214539
First Author: Lee CS
Year: 2013
Journal: FEBS J
Title: Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice.
Volume: 280
Issue: 15
Pages: 3609-20
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Publication
34215698 | J:307684
 
First Author: Yoshida Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Loss of peptide:N-glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase.
Volume: 118
Issue: 27
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Publication
19460884 | J:150738
First Author: Chaturvedi RK
Year: 2009
Journal: Hum Mol Genet
Title: Impaired PGC-1alpha function in muscle in Huntington's disease.
Volume: 18
Issue: 16
Pages: 3048-65
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Publication
17229846 | J:119525
First Author: Villena JA
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis.
Volume: 104
Issue: 4
Pages: 1418-23
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Publication
27920251 | J:244981
 
First Author: Baird L
Year: 2017
Journal: Mol Cell Biol
Title: A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways.
Volume: 37
Issue: 4
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Publication
24423644 | J:211609
 
First Author: Choi J
Year: 2014
Journal: Neurobiol Dis
Title: PGC-1α regulation of mitochondrial degeneration in experimental diabetic neuropathy.
Volume: 64
Pages: 118-30
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Publication
31920982 | J:341919
 
First Author: Pepin ME
Year: 2019
Journal: Front Endocrinol (Lausanne)
Title: Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1.
Volume: 10
Pages: 872
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Publication
29809168 | J:338283
First Author: Nath SR
Year: 2018
Journal: J Clin Invest
Title: Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
Volume: 128
Issue: 8
Pages: 3630-3641
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Publication
33554448 | J:307071
First Author: Liu L
Year: 2021
Journal: EMBO Rep
Title: Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis.
Volume: 22
Issue: 3
Pages: e50629
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Publication
11025215 | J:65400
First Author: Murphy P
Year: 2000
Journal: Mech Dev
Title: Expression of the bZIP transcription factor TCF11 and its potential dimerization partners during development.
Volume: 97
Issue: 1-2
Pages: 141-8
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Publication
16648473 | J:109069
First Author: auf dem Keller U
Year: 2006
Journal: Mol Cell Biol
Title: Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing.
Volume: 26
Issue: 10
Pages: 3773-84
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Publication
21321201 | J:170484
First Author: Shock LS
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.
Volume: 108
Issue: 9
Pages: 3630-5
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Publication
21383067 | J:172813
First Author: Sun Z
Year: 2011
Journal: Mol Cell Biol
Title: KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.
Volume: 31
Issue: 9
Pages: 1800-11
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Publication
25043031 | J:217111
First Author: Zhang Y
Year: 2014
Journal: Nature
Title: Coordinated regulation of protein synthesis and degradation by mTORC1.
Volume: 513
Issue: 7518
Pages: 440-3
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Publication
29941490 | J:265278
     
First Author: Sekine H
Year: 2018
Journal: Mol Cell Biol
Title: O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1.
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Publication
32941182 | J:331272
 
First Author: Olonisakin TF
Year: 2021
Journal: J Clin Invest
Title: Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation.
Volume: 131
Issue: 1
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Publication
17510056 | J:124618
First Author: Xing W
Year: 2007
Journal: J Biol Chem
Title: Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells.
Volume: 282
Issue: 30
Pages: 22052-61
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Publication
31971970 | J:291576
First Author: Rubinow KB
Year: 2020
Journal: PLoS One
Title: Aromatase deficiency in hematopoietic cells improves glucose tolerance in male mice through skeletal muscle-specific effects.
Volume: 15
Issue: 1
Pages: e0227830
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Publication
27060105 | J:239484
First Author: Zhang Y
Year: 2016
Journal: Biochem J
Title: Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity.
Volume: 473
Issue: 8
Pages: 961-1000
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Publication
28152064 | J:245202
First Author: Pellegrini GG
Year: 2017
Journal: PLoS One
Title: Nrf2 regulates mass accrual and the antioxidant endogenous response in bone differently depending on the sex and age.
Volume: 12
Issue: 2
Pages: e0171161
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Publication
24887203 | J:217927
First Author: Pedrós I
Year: 2014
Journal: Biochim Biophys Acta
Title: Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.
Volume: 1842
Issue: 9
Pages: 1556-66
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Publication
11167019 | J:67349
First Author: Chinenov Y
Year: 2000
Journal: Gene
Title: Isolation of a bi-directional promoter directing expression of the mouse GABPalpha and ATP synthase coupling factor 6 genes.
Volume: 261
Issue: 2
Pages: 311-20
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Publication
36535138 | J:334383
 
First Author: Xia G
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Loss of ALDH2 aggravates mitochondrial biogenesis disorder in cardiac myocytes induced by TAC.
Volume: 639
Pages: 189-196
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Protein
Q99L90
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q3TJY1
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Protein
Q3TYU7
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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