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Search results 301 to 372 out of 372 for Nsg1

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Type Details Score
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Nsg1<em1Smoc> | MGI:7291421
Name: neuron specific gene family member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429290 | C57BL/6JSmoc-Nsg1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Nsg1-EGFP)HP273Gsat | MGI:4847279
Name: transgene insertion HP273, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5003736 | STOCK Tg(Nsg1-EGFP)HP273Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Protein
Q91WG1
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
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Protein
E0CZ00
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: true
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Protein
E0CXS5
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
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Protein
E0CZ15
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
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Protein
E0CXF1
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Protein
A0A087WQP7
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
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Publication
16270032 | -
First Author: Flury I
Year: 2005
Journal: EMBO J
Title: INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins.
Volume: 24
Issue: 22
Pages: 3917-26
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Protein Domain
IPR025929 | INSIG_fam
Type: Family
Description: This family contains a number of eukaryotic Insulin-induced proteins (INSIG-1 and INSIG-2) approximately 200 residues long. INSIG-1 and INSIG-2 are found in the endoplasmic reticulum and bind the sterol-sensing domain of SREBP cleavage-activating protein (SCAP), preventing it from escorting SREBPs to the Golgi. Their combined action permits feedback regulation of cholesterol synthesis over a wide range of sterol concentrations [, ].The INSIG family also includes NSG1 and NSG2 (INSIG homologues 1 and 2) [].
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Publication
29907658 | J:267235
First Author: Yap CC
Year: 2018
Journal: J Cell Biol
Title: Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes.
Volume: 217
Issue: 9
Pages: 3141-3159
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Publication
12242332 | J:79403
First Author: Yabe D
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins.
Volume: 99
Issue: 20
Pages: 12753-8
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Protein
Q8BGI3
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Publication
12202038 | -
First Author: Yang T
Year: 2002
Journal: Cell
Title: Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
Volume: 110
Issue: 4
Pages: 489-500
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Protein
P47759
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
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Protein
Q62092
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: false
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Publication
16595675 | J:146583
First Author: Xiao J
Year: 2006
Journal: J Biol Chem
Title: Calcyon, a novel partner of clathrin light chain, stimulates clathrin-mediated endocytosis.
Volume: 281
Issue: 22
Pages: 15182-93
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Protein
Q9DCA7
Organism: Mus musculus/domesticus
Length: 226  
Fragment?: false
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Protein
Q5SS02
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
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Protein
A0A0J9YVF8
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A0J9YUH3
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Protein
Q5SS03
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
A0A0J9YTZ4
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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Protein
Q5SS04
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
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Protein
A0A0J9YVB5
Organism: Mus musculus/domesticus
Length: 33  
Fragment?: true
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Protein
Q8C5M2
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: false
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Publication
11929934 | -
First Author: Lezcano N
Year: 2002
Journal: J Neurophysiol
Title: D1/D5 dopamine receptors stimulate intracellular calcium release in primary cultures of neocortical and hippocampal neurons.
Volume: 87
Issue: 4
Pages: 2167-75
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Publication
11923911 | -
First Author: Fisher SE
Year: 2002
Journal: Am J Hum Genet
Title: A genomewide scan for loci involved in attention-deficit/hyperactivity disorder.
Volume: 70
Issue: 5
Pages: 1183-96
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Publication
12622665 | -
First Author: Koh PO
Year: 2003
Journal: Arch Gen Psychiatry
Title: Up-regulation of the D1 dopamine receptor-interacting protein, calcyon, in patients with schizophrenia.
Volume: 60
Issue: 3
Pages: 311-9
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Publication
17170272 | -
First Author: Lezcano N
Year: 2006
Journal: Science
Title: Retraction.
Volume: 314
Issue: 5806
Pages: 1681
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Publication
17885599 | -
First Author: Kruusmägi M
Year: 2007
Journal: Neuroreport
Title: Intracellular dynamics of calcyon, a neuron-specific vesicular protein.
Volume: 18
Issue: 15
Pages: 1547-51
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Publication
17623072 | -
 
First Author: Heijtz RD
Year: 2007
Journal: Behav Brain Funct
Title: Calcyon mRNA expression in the frontal-striatal circuitry and its relationship to vesicular processes and ADHD.
Volume: 3
Pages: 33
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Publication
25376768 | -
First Author: Muthusamy N
Year: 2015
Journal: J Neurochem
Title: Complementary roles of the neuron-enriched endosomal proteins NEEP21 and calcyon in neuronal vesicle trafficking.
Volume: 132
Issue: 1
Pages: 20-31
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Protein Domain
IPR009431 | NSG
Type: Family
Description: This family includes the neuron-enriched endosomal proteins NSG1 (NEEP21), NSG2 (P19) and NSG3 (calcyon, Caly). They interact with distinct elements of the endosomal and synaptic scaffolding machinery []. NSG1 and NSG2 may not be resident endosomal proteins, and are also known as neuronal vesicle trafficking-associated proteins 1 and 2 respectively []. NSG1/NEEP21 plays a role in the trafficking of multiple receptors, including the cell adhesion molecule L1/NgCAM, the neurotransmitter receptor GluA2, and beta-APP []. The role of NSG2 is not known.It was originally thought that the Neuron-specific vesicular protein calcyon (previously known as D1 dopamine receptor-interacting, calcyon), interacted directly with the D1 dopamine receptor (DRD1) to modulate neocortical and hippocampal neuronal excitability as well as cAMP-dependent signalling []. However, this work was retracted, as it was shown that a direct interaction with the dopamine D1 receptor had been misinterpreted []. However, it has been shown that calcyon induces D1DR to stimulate intracellular Ca2+ release, and this suggests a possible functional interaction between calcyon and D1DR, despite there being, as yet, no direct interaction between them. A recent study suggested that calcyon-containing vesicles might transport D1DR by associating calcyon with D1DR through their assembly to clathrin []. However, as a single transmembrane protein, it is currently not clear how calcyon can regulate the internalization of D1DR from the plasma membrane to endocytic vesicles.Calcyon is a brain-specific protein, mainly localized in the intracellular endosomal vesicles of dendritic spines in dopamine expressing pyramidal cells in the prefrontal cortex and hippocampus and dorsal striatum region []. Neuron-specific vesicular protein calcyon has implicated in clathrin-mediated endocytosis. It is exclusively expressed in neurons, and localized in moving vesicles and it thought to play a role in brain plasticity []. Defective calcyon proteins have been implicated in both attention-deficit/hyperactivity disorder (ADHD) [, ]and schizophrenia [].
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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