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Search results 301 to 400 out of 420 for Ofd1

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Type Details Score
Publication
10604990 | J:112421
First Author: Kono DH
Year: 2000
Journal: J Immunol
Title: Development of lupus in BXSB mice is independent of IL-4.
Volume: 164
Issue: 1
Pages: 38-42
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Publication
7835973 | J:21189
First Author: Rosenblatt N
Year: 1994
Journal: Immunology
Title: The Yaa gene-dependent B-cell deficiency worsens the generalized lymphadenopathy and autoimmunity of C57BL/6-gld male mice.
Volume: 83
Issue: 3
Pages: 476-83
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Publication
27228057 | J:252479
First Author: Wu YY
Year: 2016
Journal: PLoS One
Title: BANK1 Regulates IgG Production in a Lupus Model by Controlling TLR7-Dependent STAT1 Activation.
Volume: 11
Issue: 5
Pages: e0156302
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Publication
9862363 | J:52110
First Author: Santiago ML
Year: 1998
Journal: Eur J Immunol
Title: Linkage of a major quantitative trait locus to Yaa gene-induced lupus-like nephritis in (NZW x C57BL/6)F1 mice.
Volume: 28
Issue: 12
Pages: 4257-67
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Publication
15634937 | J:95829
First Author: Kikuchi S
Year: 2005
Journal: J Immunol
Title: Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis.
Volume: 174
Issue: 2
Pages: 1111-7
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Publication
10841565 | J:62719
First Author: Morel L
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.
Volume: 97
Issue: 12
Pages: 6670-5
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Publication
15494482 | J:93740
First Author: Ozaki K
Year: 2004
Journal: J Immunol
Title: Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6.
Volume: 173
Issue: 9
Pages: 5361-71
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Publication
18521959 | J:137309
First Author: Fairhurst AM
Year: 2008
Journal: Eur J Immunol
Title: Yaa autoimmune phenotypes are conferred by overexpression of TLR7.
Volume: 38
Issue: 7
Pages: 1971-8
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Publication
6886419 | J:7172
First Author: Smith HR
Year: 1983
Journal: J Immunol
Title: The effect of the X-linked immune deficiency gene (xid) upon the Y chromosome-related disease of BXSB mice.
Volume: 131
Issue: 3
Pages: 1257-62
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Publication
15048718 | J:88856
First Author: Kuroki A
Year: 2004
Journal: Eur J Immunol
Title: Enforced Bcl-2 expression in B lymphocytes induces rheumatoid factor and anti-DNA production, but the Yaa mutation promotes only anti-DNA production.
Volume: 34
Issue: 4
Pages: 1077-84
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Publication
30753473 | J:273314
First Author: Saitoh SI
Year: 2019
Journal: Int Immunol
Title: ADP-ribosylation factor-like 8b is required for the development of mouse models of systemic lupus erythematosus.
Volume: 31
Issue: 4
Pages: 225-237
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Publication
17371996 | J:145049
First Author: Rankin J
Year: 2007
Journal: J Immunol
Title: The Bxs6 locus of BXSB mice is sufficient for high-level expression of gp70 and the production of gp70 immune complexes.
Volume: 178
Issue: 7
Pages: 4395-401
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Genotype
Genotype
Symbol: Bxs6/Bxs6 Yaa/?
Background: B10.BXSB-(D13Mit3-D13Mit78) Yaa
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b<+> Yaa/?
Background: involves: C57BL/6 * FVB/N * SB/Le
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Btk/Btk Yaa/?
Background: involves: BXSB/MpJ * C57BL/6JAnu * SB/Le
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fcgrt/Fcgrt Yaa/?
Background: BXSB.129X1-Fcgrt/Dcr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tap1/Tap1 Yaa/?
Background: BXSB.129S2(B6)-Tap1/Dcr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd8a/Cd8a Yaa/?
Background: BXSB.129S2(B6)-Cd8a/4Dcr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ighm/Ighm Yaa/?
Background: BXSB.129S2(B6)-Ighm/Dcr
Zygosity: cx
Has Mutant Allele: true
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Publication
24997988 | J:213635
First Author: Thauvin-Robinet C
Year: 2014
Journal: Nat Genet
Title: The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation.
Volume: 46
Issue: 8
Pages: 905-11
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Publication
34241634 | J:307969
 
First Author: Kumar D
Year: 2021
Journal: J Cell Biol
Title: A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Volume: 220
Issue: 9
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Publication
12559564 | J:81885
 
First Author: Kenedy AA
Year: 2003
Journal: Gene
Title: Identification and characterization of the novel centrosome-associated protein CCCAP.
Volume: 303
Pages: 35-46
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Protein
Q80UF4
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
Q9CYH0
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: false
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Protein
Q05DD9
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein
E9Q2E2
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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Protein
Q8BI65
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
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Protein
Q9CSM9
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: true
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Protein
Q8R3K0
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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Protein
Q3UVU9
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
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Publication
22626039 | -
First Author: Billingsley G
Year: 2012
Journal: Ophthalmic Genet
Title: Mutational analysis of SDCCAG8 in Bardet-Biedl syndrome patients with renal involvement and absent polydactyly.
Volume: 33
Issue: 3
Pages: 150-4
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Publication
25088364 | J:215665
First Author: Insolera R
Year: 2014
Journal: Neuron
Title: SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex.
Volume: 83
Issue: 4
Pages: 805-22
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Protein Domain
IPR031887 | SDCCAG8
Type: Family
Description: Serologically defined colon cancer antigen 8 (SDCCAG8), also known as CCCAP (centrosomal colon cancer autoantigen protein), is a family of proteins found in eukaryotes. Mutations of SDCCAG8 are associated with nephronophthisis []and Bardet-Biedl syndrome [], as well as schizophrenia. SDCCAG8 is associated with the centrosome []and interacts with pericentriolar material 1 (PCM1), a centriolar satellite protein crucial for targeting proteins to the centrosome. It regulates centrosomal accumulation of pericentriolar material and neuronal polarisation and migration in the developing mouse cortex [].SDCCAG8 is localized at both centrioles and interacts directly with OFD1 (oral-facial-digital syndrome 1), which is linked to an autosomal recessive cystic kidney disease, NPHP-RC (nephronophthisis-related ciliopathies). Depletion of SDCCAG8 causes kidney cysts and a body axis defect in zebrafish [].
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Publication
10435725 | J:117314
First Author: Khaled AR
Year: 1999
Journal: Autoimmunity
Title: Aberrant expression of the NF-kappaB and IkappaB proteins in B cells from viable motheaten mice.
Volume: 30
Issue: 2
Pages: 115-28
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Strain
MGI:2174228 | BXSB.129P2(B6)-H2-K1<b-tm1Bpe> H2-D1<b-tm1Bpe>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3804879 | B6.Cg-Nba10<NZB> Tlr7<tm1Aki> Yaa
Attribute String: congenic, spontaneous mutation, targeted mutation
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Strain
MGI:5617629 | B6.Cg-Tlr7<tm1Flv> Yaa
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:5520950 | BXSB.129(Cg)-Il21r<tm1Wjl>/DcrJ
Attribute String: congenic, targeted mutation, mutant strain
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Strain
MGI:6093717 | BXSB.129S7(B6)-Rag1<tm1Mom>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6094190 | BXSB.129S6(B6)-Cd1d1<tm1Luc>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6094241 | BXSB.Cg-Cd8a<tm1Mak> Il15<tm1Imx>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4834593 | BXSB.129(Cg)-Il21r<tm1Wjl>/Dcr
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:2174226 | BXSB.B6-Prf1<tm1Sdz>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5515217 | BXSB.129S2(C)-Cd1<tm1Gru>/DcrJ
Attribute String: targeted mutation, mutant strain, congenic
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Publication
18606711 | J:137656
First Author: Santiago-Raber ML
Year: 2008
Journal: J Immunol
Title: Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus.
Volume: 181
Issue: 2
Pages: 1556-62
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Publication
19224760 | J:148718
First Author: Maeda K
Year: 2009
Journal: Blood
Title: Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals.
Volume: 113
Issue: 19
Pages: 4534-40
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Publication
35477763 | J:324448
First Author: Brown GJ
Year: 2022
Journal: Nature
Title: TLR7 gain-of-function genetic variation causes human lupus.
Volume: 605
Issue: 7909
Pages: 349-356
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Publication
16849473 | J:137977
First Author: Lin Q
Year: 2006
Journal: J Immunol
Title: Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus.
Volume: 177
Issue: 3
Pages: 1646-54
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Publication
19164519 | J:144484
First Author: Bubier JA
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice.
Volume: 106
Issue: 5
Pages: 1518-23
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Publication
37636066 | J:339615
First Author: Wilson JJ
Year: 2023
Journal: iScience
Title: Glucose oxidation-dependent survival of activated B cells provides a putative novel therapeutic target for lupus treatment.
Volume: 26
Issue: 9
Pages: 107487
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Genotype
Genotype
Symbol: Nba10/Nba10 Tlr7/? Yaa/?
Background: B6.Cg-Nba10 Tlr7 Yaa
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il21r/Il21r Yaa/?
Background: BXSB.129(Cg)-Il21r/Dcr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tlr7/? Yaa/?
Background: B6.Cg-Tlr7 Yaa
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd8a/Cd8a Il15/Il15 Yaa/?
Background: BXSB.Cg-Cd8a Il15/Dcr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2-D1/H2-D1 H2-K1/H2-K1 Yaa/?
Background: BXSB.129P2(B6)-H2-K1 H2-D1/Dcr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd1d1/Cd1d1 Yaa/?
Background: BXSB.129S6(B6)-Cd1d1/Dcr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prf1/Prf1 Yaa/?
Background: BXSB.B6-Prf1/Dcr
Zygosity: cx
Has Mutant Allele: true
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Publication
22940612 | J:188915
First Author: Di Gioia SA
Year: 2012
Journal: Hum Mol Genet
Title: FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies.
Volume: 21
Issue: 23
Pages: 5174-84
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Publication
10395802 | J:56272
First Author: Prakash SK
Year: 1999
Journal: Genomics
Title: Characterization of a novel chromo domain gene in xp22.3 with homology to Drosophila msl-3.
Volume: 59
Issue: 1
Pages: 77-84
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Publication
25103236 | J:226879
First Author: Lee YL
Year: 2014
Journal: Mol Biol Cell
Title: Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function.
Volume: 25
Issue: 19
Pages: 2919-33
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Publication
12974753 | J:109815
First Author: Wilber A
Year: 2003
Journal: Clin Exp Immunol
Title: Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.
Volume: 134
Issue: 1
Pages: 46-52
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Strain
MGI:3812164 | EOD
Attribute String: recombinant inbred (RI), mutant strain, spontaneous mutation, transposition
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Strain
MGI:6353908 | EOD/ThpNkcRbrc
Attribute String: inbred strain
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Strain
MGI:5608583 | B6.Cg-Fcgr2b<tm1Ttk> Yaa
Attribute String: congenic, mutant strain, spontaneous mutation, chromosome aberration, targeted mutation
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Strain
MGI:5617613 | B6.Cg-Fcgr2b<tm1Ttk> Tlr7<tm1Flv> Yaa
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:6162237 | EOD/ThpNkc
Attribute String: recombinant inbred (RI)
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Strain
MGI:5572917 | BXSB.Cg-Fcgrt<tm1Dcr> Tg(FCGRT)99Dcr/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
2599002 | J:108759
First Author: Merino R
Year: 1989
Journal: Eur J Immunol
Title: Differential effect of the autoimmune Yaa and lpr genes on the acceleration of lupus-like syndrome in MRL/MpJ mice.
Volume: 19
Issue: 11
Pages: 2131-7
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Publication
762500 | J:108760
First Author: Theofilopoulos AN
Year: 1979
Journal: J Exp Med
Title: Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.
Volume: 149
Issue: 2
Pages: 516-34
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Publication
3931946 | J:109825
First Author: Pisetsky DS
Year: 1985
Journal: Clin Immunol Immunopathol
Title: The influence of Yaa on anti-DNA responses of B6-lpr mice.
Volume: 37
Issue: 3
Pages: 369-76
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Publication
18581336 | J:137453
First Author: Anders HJ
Year: 2008
Journal: Eur J Immunol
Title: Molecular mimicry in innate immunity? The viral RNA recognition receptor TLR7 accelerates murine lupus.
Volume: 38
Issue: 7
Pages: 1795-9
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Publication
26439309 | J:253097
First Author: Elewa YH
Year: 2016
Journal: Immunology
Title: Comparative analysis of mediastinal fat-associated lymphoid cluster development and lung cellular infiltration in murine autoimmune disease models and the corresponding normal control strains.
Volume: 147
Issue: 1
Pages: 30-40
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Publication
33384689 | J:312304
 
First Author: Masum MA
Year: 2020
Journal: Front Immunol
Title: Vasculature-Associated Lymphoid Tissue: A Unique Tertiary Lymphoid Tissue Correlates With Renal Lesions in Lupus Nephritis Mouse Model.
Volume: 11
Pages: 595672
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Publication
23175700 | J:190844
First Author: Baccala R
Year: 2012
Journal: J Immunol
Title: Anti-IFN-α/β receptor antibody treatment ameliorates disease in lupus-predisposed mice.
Volume: 189
Issue: 12
Pages: 5976-84
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Publication
28267197 | J:246255
First Author: Tran NL
Year: 2017
Journal: Eur J Immunol
Title: TACI-dependent APRIL signaling maintains autoreactive B cells in a mouse model of systemic lupus erythematosus.
Volume: 47
Issue: 4
Pages: 713-723
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Publication
8597884 | J:30518
First Author: Kamada H
Year: 1995
Journal: Inflamm Res
Title: Effect of cyclophosphamide on lymphokine production in MRL/lpr.Yaa mice.
Volume: 44
Issue: 11
Pages: 491-8
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Publication
21233417 | J:169125
First Author: Kim HJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice.
Volume: 108
Issue: 5
Pages: 2010-5
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Publication
8477802 | J:4970
First Author: Suzuki H
Year: 1993
Journal: Eur J Immunol
Title: Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal.
Volume: 23
Issue: 5
Pages: 1078-82
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Publication
29190833 | J:256473
First Author: Horvei KD
Year: 2017
Journal: PLoS One
Title: Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.
Volume: 12
Issue: 11
Pages: e0188863
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Publication
38169466 | J:345002
First Author: Ni H
Year: 2024
Journal: Nat Commun
Title: Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice.
Volume: 15
Issue: 1
Pages: 1
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Publication
35438841 | J:336755
First Author: Chen Z
Year: 2022
Journal: Arthritis Rheumatol
Title: Interleukin-13 Receptor α1-Mediated Signaling Regulates Age-Associated/Autoimmune B Cell Expansion and Lupus Pathogenesis.
Volume: 74
Issue: 9
Pages: 1544-1555
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Publication
8601623 | J:32235
First Author: Takahashi S
Year: 1996
Journal: J Clin Invest
Title: Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice.
Volume: 97
Issue: 7
Pages: 1597-604
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Publication
14514727 | J:131473
First Author: Yoh K
Year: 2003
Journal: J Am Soc Nephrol
Title: Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background.
Volume: 14
Issue: 10
Pages: 2494-502
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Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b<+> Yaa/?
Background: involves: 129S4/SvJae * C57BL/6 * SB/Le
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b Tlr7/? Yaa/?
Background: B6.Cg-Fcgr2b Tlr7 Yaa
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b Yaa/?
Background: B6.Cg-Fcgr2b Yaa
Zygosity: cx
Has Mutant Allele: true
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Publication
18677469 | J:140028
First Author: Zhang MC
Year: 2008
Journal: Immunogenetics
Title: Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice.
Volume: 60
Issue: 10
Pages: 599-607
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Publication
3553324 | J:32752
First Author: Leiter EH
Year: 1987
Journal: J Immunol
Title: Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.
Volume: 138
Issue: 10
Pages: 3224-9
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Strain
MGI:6162236 | EOD/ThpNkc-Bloc1s4<cno2>/Nkc
Attribute String: coisogenic, mutant strain, spontaneous mutation
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Publication
32253245 | J:288630
First Author: Chodisetti SB
Year: 2020
Journal: J Immunol
Title: Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development.
Volume: 204
Issue: 10
Pages: 2641-2650
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Publication
30026744 | J:264769
 
First Author: Weisenburger T
Year: 2018
Journal: Front Immunol
Title: Epistatic Interactions Between Mutations of Deoxyribonuclease 1-Like 3 and the Inhibitory Fc Gamma Receptor IIB Result in Very Early and Massive Autoantibodies Against Double-Stranded DNA.
Volume: 9
Pages: 1551
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Publication
32269165 | J:292469
 
First Author: Chen PM
Year: 2020
Journal: Sci Transl Med
Title: Kidney tissue hypoxia dictates T cell-mediated injury in murine lupus nephritis.
Volume: 12
Issue: 538
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Publication
1592043 | J:2361
First Author: Shimizu M
Year: 1992
Journal: Electrophoresis
Title: Cell electrophoretic characterization of abnormally expanded lymphocytes in autoimmune lprcg, lpr, gld and Yaa mice, and of thymocyte subsets.
Volume: 13
Issue: 3
Pages: 136-42
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Publication
16709748 | J:109758
First Author: Pisitkun P
Year: 2006
Journal: Science
Title: Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication.
Volume: 312
Issue: 5780
Pages: 1669-72
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Publication
8025960 | J:19169
First Author: Rosenblatt N
Year: 1994
Journal: Cell Immunol
Title: The Yaa mutation induces the development of autoimmunity in mice heterozygous for the gld (generalized lymphadenopathy disease) mutation.
Volume: 156
Issue: 2
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