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Search results 301 to 400 out of 1772 for Parkinson

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Type Details Score
Interaction Experiment
Description: Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Publication
First Author: Tomac AC
Year: 2001
Journal: Cytogenet Cell Genet
Title: Assignment of the mouse Park2 (PARKIN), the homologue to a new human Parkinson candidate gene, to the telomeric region of mouse 17A3.2-3.3, by in situ hybridization.
Volume: 95
Issue: 1-2
Pages: 120-1
Publication
First Author: Deng H
Year: 2007
Journal: Arch Neurol
Title: A family with Parkinson disease, essential tremor, bell palsy, and parkin mutations.
Volume: 64
Issue: 3
Pages: 421-4
Publication  
First Author: Madeo G
Year: 2012
Journal: Neuroscience
Title: Aberrant striatal synaptic plasticity in monogenic parkinsonisms.
Volume: 211
Pages: 126-35
Publication
First Author: Usami Y
Year: 2011
Journal: Neurobiol Dis
Title: DJ-1 associates with synaptic membranes.
Volume: 43
Issue: 3
Pages: 651-62
Publication
First Author: Choi DJ
Year: 2020
Journal: Glia
Title: Critical roles of astrocytic-CCL2-dependent monocyte infiltration in a DJ-1 knockout mouse model of delayed brain repair.
Volume: 68
Issue: 10
Pages: 2086-2101
Publication  
First Author: Hennis MR
Year: 2014
Journal: Neurobiol Dis
Title: Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson's disease.
Volume: 62
Pages: 113-23
Publication  
First Author: Moreira CG
Year: 2020
Journal: Neuropharmacology
Title: Improved functional and histochemical outcomes in l-DOPA plus tolcapone treated VMAT2-deficient mice.
Volume: 181
Pages: 108353
Publication  
First Author: Moutaoufik MT
Year: 2019
Journal: iScience
Title: Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Volume: 19
Pages: 1114-1132
Publication
First Author: Evsyukov V
Year: 2017
Journal: Dis Model Mech
Title: Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models.
Volume: 10
Issue: 5
Pages: 633-643
Allele    
Name: Parkinson disease (autosomal recessive, early onset) 7; wild type
Allele  
Name: solute carrier family 18 (vesicular monoamine), member 2; targeted mutation 2, Katrin A Mooslehner
Allele Type: Targeted
Publication  
First Author: Ding Y
Year: 2017
Journal: Exp Eye Res
Title: Increased susceptibility to fundus camera-delivered light-induced retinal degeneration in mice deficient in oxidative stress response proteins.
Volume: 159
Pages: 58-68
Publication
First Author: Zhu Y
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging.
Volume: 60
Issue: 12
Pages: 3740-3751
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Bonifati V
Year: 2003
Journal: Science
Title: Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
Volume: 299
Issue: 5604
Pages: 256-9
Publication
First Author: Guo T
Year: 2024
Journal: Aging Cell
Title: N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson's disease.
Volume: 23
Issue: 5
Pages: e14124
Publication
First Author: Xiong R
Year: 2014
Journal: Neurobiol Aging
Title: MicroRNA-494 reduces DJ-1 expression and exacerbates neurodegeneration.
Volume: 35
Issue: 3
Pages: 705-14
Publication
First Author: Yokota T
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition.
Volume: 312
Issue: 4
Pages: 1342-8
Publication
First Author: Hayashi T
Year: 2009
Journal: Biochem Biophys Res Commun
Title: DJ-1 binds to mitochondrial complex I and maintains its activity.
Volume: 390
Issue: 3
Pages: 667-72
Publication
First Author: Zhang L
Year: 2005
Journal: Hum Mol Genet
Title: Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis.
Volume: 14
Issue: 14
Pages: 2063-73
Publication
First Author: Nagakubo D
Year: 1997
Journal: Biochem Biophys Res Commun
Title: DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras.
Volume: 231
Issue: 2
Pages: 509-13
Publication
First Author: Okada M
Year: 2002
Journal: Biol Pharm Bull
Title: DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice.
Volume: 25
Issue: 7
Pages: 853-6
Publication
First Author: van der Brug MP
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.
Volume: 105
Issue: 29
Pages: 10244-9
Publication
First Author: Mullett SJ
Year: 2009
Journal: Neurobiol Dis
Title: DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone.
Volume: 33
Issue: 1
Pages: 28-36
Publication  
First Author: Larsen NJ
Year: 2011
Journal: Neuroscience
Title: DJ-1 knock-down impairs astrocyte mitochondrial function.
Volume: 196
Pages: 251-64
Publication
First Author: Zhang Q
Year: 2012
Journal: Biochem J
Title: DJ-1 promotes the proteasomal degradation of Fis1: implications of DJ-1 in neuronal protection.
Volume: 447
Issue: 2
Pages: 261-9
Publication
First Author: Kato I
Year: 2013
Journal: Mol Cell Biol
Title: Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner.
Volume: 33
Issue: 2
Pages: 340-59
Publication
First Author: Maita C
Year: 2013
Journal: PLoS One
Title: Monomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants.
Volume: 8
Issue: 1
Pages: e54087
Publication
First Author: Sajjad MU
Year: 2014
Journal: Hum Mol Genet
Title: DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease.
Volume: 23
Issue: 3
Pages: 755-66
Publication
First Author: Rannikko EH
Year: 2013
Journal: J Neurochem
Title: Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion.
Volume: 125
Issue: 2
Pages: 314-27
Publication
First Author: Heo JY
Year: 2012
Journal: PLoS One
Title: DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly.
Volume: 7
Issue: 3
Pages: e32629
Publication  
First Author: Pan G
Year: 2022
Journal: Hum Exp Toxicol
Title: Parkinson's disease protein 7 protected against oxidative stress of myocardial infarction direct through p47phox and nicotinamide adenine dinucleotide phosphate oxidase 4.
Volume: 41
Pages: 9603271221124099
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944923
Age: embryonic day 11.5
Image: g00360 E11.5
Specimen Label: g00360 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944923
Age: embryonic day 11.5
Image: g00360 E11.5
Specimen Label: g00360 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944923
Age: embryonic day 11.5
Image: g00360 E11.5
Specimen Label: g00360 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944923
Age: embryonic day 11.5
Image: g00360 E11.5
Specimen Label: g00360 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944923
Age: embryonic day 11.5
Image: g00360 E11.5
Specimen Label: g00360 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944923
Age: embryonic day 15.5
Image: g00360 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00360 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884467
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944923
Age: postnatal day 7
Image: g00360 P7
Specimen Label: g00360 P7
Detected: true
Specimen Num: 3
DO Term
DO Term
DO Term
DO Term
DO Term
DO Term
Allele
Name: VPS35 retromer complex component; gene trap RRK261, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
Allele
Name: transgene insertion 1S13, Herman van der Putten
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Transgene
Type: transgene
Organism: mouse, laboratory
Allele
Name: VPS35 retromer complex component; targeted mutation 1.1, Hung-Li Wang
Allele Type: Targeted
Attribute String: Humanized sequence
Genotype
Symbol: Tg(Thy1-Snca)1S13Putt/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Vps35/Vps35<+>
Background: B6.129P2-Vps35
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Vps35/Vps35<+>
Background: involves: 129S/SvEv * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Gene
Type: gene
Organism: human
Publication
First Author: Knippenberg S
Year: 2013
Journal: J Neuropathol Exp Neurol
Title: Altered expression of DJ-1 and PINK1 in sporadic ALS and in the SOD1(G93A) ALS mouse model.
Volume: 72
Issue: 11
Pages: 1052-61
Publication
First Author: Sanderson CM
Year: 1996
Journal: J Virol
Title: Overexpression of the vaccinia virus A38L integral membrane protein promotes Ca2+ influx into infected cells.
Volume: 70
Issue: 2
Pages: 905-14
Publication
First Author: Fahrner KA
Year: 1994
Journal: J Mol Biol
Title: A mutant hook-associated protein (HAP3) facilitates torsionally induced transformations of the flagellar filament of Escherichia coli.
Volume: 238
Issue: 2
Pages: 173-86
Publication
First Author: Arold ST
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: H-NS forms a superhelical protein scaffold for DNA condensation.
Volume: 107
Issue: 36
Pages: 15728-32
Publication
First Author: Morrissey PJ
Year: 1980
Journal: J Immunol
Title: Immunologic abnormalities in HRS/J mice. I. Specific deficit in T lymphocyte helper function in a mutant mouse.
Volume: 125
Issue: 4
Pages: 1558-62
Publication
First Author: Jamontt J
Year: 2013
Journal: J Immunol
Title: Nucleotide-binding oligomerization domain 2 signaling promotes hyperresponsive macrophages and colitis in IL-10-deficient mice.
Volume: 190
Issue: 6
Pages: 2948-58