Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:461764 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679823 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4827116 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000057_21 |
|
Specimen Label: |
euxassay_000057_21 |
Detected: |
true |
Specimen Num: |
22 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310458 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1768022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423781 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the skull (base and vault). |
Specimen Label: |
EH176; Specimen C2172 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310458 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423781 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in whisker follicle. |
Specimen Label: |
EH176; Specimen C2172 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida K |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Opposing Ventral Striatal Medium Spiny Neuron Activities Shaped by Striatal Parvalbumin-Expressing Interneurons during Goal-Directed Behaviors. |
Volume: |
31 |
Issue: |
13 |
Pages: |
107829 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bouchekioua Y |
Year: |
2017 |
Journal: |
Neurosci Res |
Title: |
Striatonigral direct pathway activation is sufficient to induce repetitive behaviors. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki E |
Year: |
2021 |
Journal: |
Eur J Neurosci |
Title: |
M1 muscarinic acetylcholine receptor-mediated inhibition of GABA release from striatal medium spiny neurons onto cholinergic interneurons. |
Volume: |
53 |
Issue: |
3 |
Pages: |
796-813 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kono A |
Year: |
2023 |
Journal: |
Neuropsychopharmacol Rep |
Title: |
Inhibition of the dorsomedial striatal direct pathway is essential for the execution of action sequences. |
Volume: |
43 |
Issue: |
3 |
Pages: |
414-424 |
|
•
•
•
•
•
|
Publication |
First Author: |
Natsubori A |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
Ventrolateral Striatal Medium Spiny Neurons Positively Regulate Food-Incentive, Goal-Directed Behavior Independently of D1 and D2 Selectivity. |
Volume: |
37 |
Issue: |
10 |
Pages: |
2723-2733 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bepari AK |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Identification of optogenetically activated striatal medium spiny neurons by Npas4 expression. |
Volume: |
7 |
Issue: |
12 |
Pages: |
e52783 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dobrowolski SF |
Year: |
2016 |
Journal: |
Mol Genet Metab |
Title: |
DNA methylation in the pathophysiology of hyperphenylalaninemia in the PAH(enu2) mouse model of phenylketonuria. |
Volume: |
119 |
Issue: |
1-2 |
Pages: |
1-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnson HL |
Year: |
2013 |
Journal: |
BMC Genomics |
Title: |
Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption. |
Volume: |
14 |
|
Pages: |
678 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koopmans F |
Year: |
2019 |
Journal: |
Neuron |
Title: |
SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. |
Volume: |
103 |
Issue: |
2 |
Pages: |
217-234.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Niewiadomska-Cimicka A |
Year: |
2017 |
Journal: |
Mol Neurobiol |
Title: |
Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders. |
Volume: |
54 |
Issue: |
5 |
Pages: |
3859-3878 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmidt H |
Year: |
2016 |
Journal: |
Eur J Neurosci |
Title: |
Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3. |
Volume: |
44 |
Issue: |
12 |
Pages: |
2991-3000 |
|
•
•
•
•
•
|
Publication |
First Author: |
Omori K |
Year: |
2007 |
Journal: |
Circ Res |
Title: |
Overview of PDEs and their regulation. |
Volume: |
100 |
Issue: |
3 |
Pages: |
309-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang N |
Year: |
2022 |
Journal: |
Neuron |
Title: |
Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures. |
Volume: |
110 |
Issue: |
20 |
Pages: |
3318-3338.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniPathway vocabulary mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Visel A |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
Volume: |
32 |
Issue: |
Database issue |
Pages: |
D552-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
797
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Polito M |
Year: |
2015 |
Journal: |
eNeuro |
Title: |
Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3). |
Volume: |
2 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fujishige K |
Year: |
1999 |
Journal: |
Eur J Biochem |
Title: |
Striatum- and testis-specific phosphodiesterase PDE10A isolation and characterization of a rat PDE10A. |
Volume: |
266 |
Issue: |
3 |
Pages: |
1118-27 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, chromosome 17, Y Yu |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
deletion, mutant stock, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(17Scaf8-Pde10a)2Yey/+ Ts(17<16>)65Dn/? |
Background: |
involves: 129S7/SvEvBrd * DBA/2J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng Y |
Year: |
2018 |
Journal: |
Nat Neurosci |
Title: |
Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a. |
Volume: |
21 |
Issue: |
12 |
Pages: |
1689-1703 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siemes D |
Year: |
2023 |
Journal: |
Cells |
Title: |
Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function. |
Volume: |
12 |
Issue: |
20 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pathak G |
Year: |
2017 |
Journal: |
Mol Psychiatry |
Title: |
PDE11A negatively regulates lithium responsivity. |
Volume: |
22 |
Issue: |
12 |
Pages: |
1714-1724 |
|
•
•
•
•
•
|
Publication |
First Author: |
Geertsma HM |
Year: |
2022 |
Journal: |
Hum Mol Genet |
Title: |
Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation. |
Volume: |
31 |
Issue: |
21 |
Pages: |
3613-3628 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xing Z |
Year: |
2023 |
Journal: |
Hum Mol Genet |
Title: |
Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome. |
Volume: |
32 |
Issue: |
13 |
Pages: |
2205-2218 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andergassen D |
Year: |
2019 |
Journal: |
PLoS Genet |
Title: |
The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes. |
Volume: |
15 |
Issue: |
7 |
Pages: |
e1008268 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertoglio D |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
MR-based spatial normalization improves [18F]MNI-659 PET regional quantification and detectability of disease effect in the Q175 mouse model of Huntington's disease. |
Volume: |
13 |
Issue: |
10 |
Pages: |
e0206613 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng J |
Year: |
2020 |
Journal: |
Autophagy |
Title: |
Microglial autophagy defect causes parkinson disease-like symptoms by accelerating inflammasome activation in mice. |
Volume: |
16 |
Issue: |
12 |
Pages: |
2193-2205 |
|
•
•
•
•
•
|
Publication |
First Author: |
Laprairie RB |
Year: |
2019 |
Journal: |
Neurochem Int |
Title: |
Huntington's disease pattern of transcriptional dysregulation in the absence of mutant huntingtin is produced by knockout of neuronal GLT-1. |
Volume: |
123 |
|
Pages: |
85-94 |
|
•
•
•
•
•
|