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Search results 301 to 400 out of 593 for Pdk1

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Hits by Strain

Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692216
Age: postnatal adult
Image: UC Davis_1865831
Specimen Label: UC Davis_1865831
Detected: true
Specimen Num: 30
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692216
Age: postnatal adult
Image: UC Davis_1865832
Specimen Label: UC Davis_1865832
Detected: true
Specimen Num: 31
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_10
Specimen Label: euxassay_001737_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_11
Specimen Label: euxassay_001737_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_12
Specimen Label: euxassay_001737_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_14
Specimen Label: euxassay_001737_14
Detected: true
Specimen Num: 13
GXD Expression
Probe: MGI:3725008
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421659
Age: embryonic day 14.5
Image: MH1723; Specimen C1824
Note: Expression was detected in whisker follicle.
Specimen Label: MH1723; Specimen C1824
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_09
Specimen Label: euxassay_001737_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_10
Specimen Label: euxassay_001737_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_11
Specimen Label: euxassay_001737_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_12
Specimen Label: euxassay_001737_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_13
Specimen Label: euxassay_001737_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_14
Specimen Label: euxassay_001737_14
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_15
Specimen Label: euxassay_001737_15
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1611074
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827132
Age: embryonic day 14.5
Image: euxassay_001737_16
Specimen Label: euxassay_001737_16
Detected: true
Specimen Num: 15
UniProt Feature
Begin: 232
Description: Phosphoserine; by PDK1
Type: modified residue
End: 232
Publication
First Author: Bone HK
Year: 2007
Journal: J Cell Sci
Title: Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis.
Volume: 120
Issue: Pt 10
Pages: 1752-62
Publication
First Author: Mora A
Year: 2005
Journal: Biochem J
Title: Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure.
Volume: 385
Issue: Pt 3
Pages: 639-48
Publication
First Author: Heinemann-Yerushalmi L
Year: 2021
Journal: Dev Cell
Title: BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development.
Volume: 56
Issue: 8
Pages: 1182-1194.e6
Publication
First Author: Tominaga Y
Year: 2005
Journal: Mol Cell Biol
Title: Translational deregulation in PDK-1-/- embryonic stem cells.
Volume: 25
Issue: 19
Pages: 8465-75
Publication
First Author: Gao W
Year: 2020
Journal: Cell Death Dis
Title: Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.
Volume: 11
Issue: 10
Pages: 919
Publication
First Author: Yang ZH
Year: 2020
Journal: Mol Cell
Title: A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.
Volume: 80
Issue: 2
Pages: 296-310.e6
Publication  
First Author: Kawakami H
Year: 2023
Journal: Dev Biol
Title: Sall4 restricts glycolytic metabolism in limb buds through transcriptional regulation of glycolytic enzyme genes.
Volume: 501
Pages: 28-38
Publication
First Author: Remy I
Year: 2004
Journal: Mol Cell Biol
Title: Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt.
Volume: 24
Issue: 4
Pages: 1493-504
Publication
First Author: Zamfirescu RC
Year: 2021
Journal: Am J Physiol Cell Physiol
Title: mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.
Volume: 320
Issue: 1
Pages: C30-C44
Publication
First Author: Dong X
Year: 2022
Journal: Nat Neurosci
Title: Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex.
Volume: 25
Issue: 7
Pages: 865-875
Publication
First Author: Vila IK
Year: 2017
Journal: Cancer Cell
Title: A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy.
Volume: 31
Issue: 2
Pages: 208-224
Publication    
First Author: Roy A
Year: 2015
Journal: Elife
Title: Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.
Volume: 4
Publication    
First Author: Travisano SI
Year: 2019
Journal: Elife
Title: Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade.
Volume: 8
Publication
First Author: Bonney S
Year: 2016
Journal: J Neurosci
Title: Diverse Functions of Retinoic Acid in Brain Vascular Development.
Volume: 36
Issue: 29
Pages: 7786-801
Publication
First Author: Cargill K
Year: 2019
Journal: J Am Soc Nephrol
Title: Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation.
Volume: 30
Issue: 7
Pages: 1192-1205
Publication
First Author: Torregrosa-Carrión R
Year: 2021
Journal: Sci Adv
Title: Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development.
Volume: 7
Issue: 46
Pages: eabj5445
Publication
First Author: Hölscher M
Year: 2011
Journal: J Biol Chem
Title: Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury.
Volume: 286
Issue: 13
Pages: 11185-94
Publication
First Author: Lange C
Year: 2016
Journal: EMBO J
Title: Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
Volume: 35
Issue: 9
Pages: 924-41
Publication
First Author: Menendez-Montes I
Year: 2021
Journal: iScience
Title: Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.
Volume: 24
Issue: 2
Pages: 102124
Publication
First Author: Hyvärinen J
Year: 2010
Journal: J Biol Chem
Title: Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Volume: 285
Issue: 18
Pages: 13646-57
Publication  
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
Publication
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
Publication
First Author: Chen X
Year: 2013
Journal: Blood
Title: PDK1 regulates platelet activation and arterial thrombosis.
Volume: 121
Issue: 18
Pages: 3718-26
Publication
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
Publication  
First Author: Yorgan TA
Year: 2019
Journal: Bone
Title: Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.
Volume: 127
Pages: 155-163
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Sandu C
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.
Volume: 291
Issue: 5
Pages: G868-76
Publication
First Author: Baracho GV
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PDK1 regulates B cell differentiation and homeostasis.
Volume: 111
Issue: 26
Pages: 9573-8
Publication
First Author: Hu T
Year: 2017
Journal: Sci Rep
Title: PDK1 plays a vital role on hematopoietic stem cell function.
Volume: 7
Issue: 1
Pages: 4943
Publication
First Author: Bayascas JR
Year: 2005
Journal: Curr Biol
Title: Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.
Volume: 15
Issue: 20
Pages: 1839-46
Publication
First Author: Xu M
Year: 2019
Journal: Cereb Cortex
Title: PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice.
Volume: 29
Issue: 3
Pages: 1185-1198
Publication
First Author: Han Z
Year: 2015
Journal: PLoS One
Title: Deletion of PDK1 causes cardiac sodium current reduction in mice.
Volume: 10
Issue: 3
Pages: e0122436
Publication
First Author: Rexhepaj R
Year: 2006
Journal: FASEB J
Title: Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice.
Volume: 20
Issue: 13
Pages: 2214-22
Strain
Attribute String: congenic, targeted mutation
Protein
Organism: Mus musculus/domesticus
Length: 559  
Fragment?: false
Publication
First Author: Shumilina E
Year: 2010
Journal: Cell Physiol Biochem
Title: Phosphoinositide-dependent kinase PDK1 in the regulation of Ca2+ entry into mast cells.
Volume: 26
Issue: 4-5
Pages: 699-706
Publication
First Author: Ito K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PDK1 coordinates survival pathways and beta-adrenergic response in the heart.
Volume: 106
Issue: 21
Pages: 8689-94
Publication
First Author: Venigalla RK
Year: 2013
Journal: EMBO J
Title: PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
Volume: 32
Issue: 7
Pages: 1008-22
Publication
First Author: He J
Year: 2019
Journal: Cell Death Differ
Title: Stage-specific requirement of kinase PDK1 for NK cells development and activation.
Volume: 26
Issue: 10
Pages: 1918-1928
Publication
First Author: Lawlor MA
Year: 2002
Journal: EMBO J
Title: Essential role of PDK1 in regulating cell size and development in mice.
Volume: 21
Issue: 14
Pages: 3728-38