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Search results 301 to 400 out of 523 for Pkm

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3557722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2008-02-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3769782
Age: embryonic day 14.5
Image: 3A
Specimen Label: 3A
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2008-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:3769782
Age: embryonic day 14.5
Image: MH1052
Note: Expression is elevated in the ventricular zone that lines the left ventricles.
Specimen Label: MH1052
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2008-02-05
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3769782
Age: embryonic day 14.5
Image: 3A
Specimen Label: 3A
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2008-02-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273022
Stage: TS22
Assay Id: MGI:3769782
Age: embryonic day 14.5
Image: 3A
Note: There is no expression in the axial cartilage.
Specimen Label: 3A
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2008-02-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3769782
Age: embryonic day 14.5
Image: 3A
Specimen Label: 3A
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Specimen Label: MH1052; Specimen C1617
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3609730
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3610138
Age: embryonic day 14.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3609730
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3610138
Age: embryonic day 16.5
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Note: Expression was detected in the skull (base and vault).
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3724749
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421403
Age: embryonic day 14.5
Image: MH1052; Specimen C1617
Note: Expression was detected in whisker follicle.
Specimen Label: MH1052; Specimen C1617
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7580825
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7581046
Age: postnatal adult
Note: Expressed in the nuclei of cardiomyocytes stained with myosin heavy chain (MHC).
Specimen Label: 1D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7580825
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7581046
Age: postnatal adult
Note: Expressed in the nuclei of cardiomyocytes stained with myosin heavy chain (MHC).
Specimen Label: 1D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7580833
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7581047
Age: postnatal adult
Note: Expressed in the nuclei of cardiomyocytes stained with myosin heavy chain (MHC).
Specimen Label: 1E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7580833
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7581047
Age: postnatal adult
Note: Expressed in the nuclei of cardiomyocytes stained with myosin heavy chain (MHC).
Specimen Label: 1E
Detected: true
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
   
Probe: MGI:7580825
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3747528
Stage: TS28
Assay Id: MGI:7581046
Age: postnatal adult
Note: No expression in the cardiomyocytes stained with myosin heavy chain (MHC) in the mutant.
Specimen Label: S5B
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7580825
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3747528
Stage: TS28
Assay Id: MGI:7581046
Age: postnatal adult
Note: No expression in the cardiomyocytes stained with myosin heavy chain (MHC) in the mutant.
Specimen Label: S5B
Detected: false
Specimen Num: 2
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Publication
7616504 | J:25686
First Author: López-Alañón DM
Year: 1995
Journal: J Reprod Fertil
Title: Cloning and characterization of genes expressed during gametogenesis of female and male mice.
Volume: 103
Issue: 2
Pages: 323-9
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Publication
27199445 | J:246535
First Author: Boeckel JN
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting With Pyruvate Kinase M2 in Endothelial Cells.
Volume: 36
Issue: 7
Pages: 1425-33
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Publication
37460614 | J:359987
First Author: Toller-Kawahisa JE
Year: 2023
Journal: Nat Commun
Title: The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils.
Volume: 14
Issue: 1
Pages: 4280
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Publication
25215489 | J:214948
First Author: Wang YH
Year: 2014
Journal: Cell
Title: Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis.
Volume: 158
Issue: 6
Pages: 1309-1323
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Publication
38565291 | J:354305
 
First Author: Liu Y
Year: 2024
Journal: J Neurosci
Title: Imbalance in Glucose Metabolism Regulates the Transition of Microglia from Homeostasis to Disease-Associated Microglia Stage 1.
Volume: 44
Issue: 20
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Publication
25313047 | J:216575
First Author: Lindsay KJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina.
Volume: 111
Issue: 43
Pages: 15579-84
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Publication
35303422 | J:339142
First Author: Pan RY
Year: 2022
Journal: Cell Metab
Title: Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer's disease.
Volume: 34
Issue: 4
Pages: 634-648.e6
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Publication
34487377 | J:350943
First Author: Liu F
Year: 2021
Journal: EMBO J
Title: PKM2-TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability.
Volume: 40
Issue: 22
Pages: e108065
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Publication
32078387 | J:304342
First Author: Magadum A
Year: 2020
Journal: Circulation
Title: Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration.
Volume: 141
Issue: 15
Pages: 1249-1265
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Publication
28598329 | J:256958
   
First Author: Chinchore Y
Year: 2017
Journal: Elife
Title: Glycolytic reliance promotes anabolism in photoreceptors.
Volume: 6
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Publication
30996297 | J:279914
First Author: Kim Y
Year: 2019
Journal: Sci Rep
Title: Loss of PKM2 in Lgr5+ intestinal stem cells promotes colitis-associated colorectal cancer.
Volume: 9
Issue: 1
Pages: 6212
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Publication
32679047 | J:304028
First Author: Hao L
Year: 2021
Journal: J Invest Dermatol
Title: Inhibiting Protein Kinase Activity of Pyruvate Kinase M2 by SIRT2 Deacetylase Attenuates Psoriasis.
Volume: 141
Issue: 2
Pages: 355-363.e6
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Publication
32812866 | J:298650
   
First Author: Walls JF
Year: 2020
Journal: Elife
Title: Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses.
Volume: 9
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Publication
30455376 | J:302786
First Author: Kong Q
Year: 2019
Journal: Diabetes
Title: HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization.
Volume: 68
Issue: 2
Pages: 361-376
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Publication
33526685 | J:302298
 
First Author: Sinha T
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Absence of retbindin blocks glycolytic flux, disrupts metabolic homeostasis, and leads to photoreceptor degeneration.
Volume: 118
Issue: 6
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Publication
35821123 | J:326759
First Author: Zhao J
Year: 2022
Journal: Cell Death Dis
Title: Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.
Volume: 13
Issue: 7
Pages: 594
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Publication
9006960 | J:38684
First Author: Roche E
Year: 1997
Journal: J Biol Chem
Title: Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line (INS-1).
Volume: 272
Issue: 5
Pages: 3091-8
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Publication
20847263 | J:163985
First Author: Vander Heiden MG
Year: 2010
Journal: Science
Title: Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
Volume: 329
Issue: 5998
Pages: 1492-9
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Publication
24120661 | J:205984
First Author: Lv L
Year: 2013
Journal: Mol Cell
Title: Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization.
Volume: 52
Issue: 3
Pages: 340-52
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Publication
37734200 | J:342138
First Author: Hu X
Year: 2023
Journal: Int Immunopharmacol
Title: Fibrinogen-like protein 2 regulates macrophage glycolytic reprogramming by directly targeting PKM2 and exacerbates alcoholic liver injury.
Volume: 124
Issue: Pt B
Pages: 110957
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Publication
37626853 | J:339993
 
First Author: Weh E
Year: 2023
Journal: Cells
Title: Metabolic Alterations Caused by Simultaneous Loss of HK2 and PKM2 Leads to Photoreceptor Dysfunction and Degeneration.
Volume: 12
Issue: 16
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Publication
39004743 | J:360829
First Author: Guo J
Year: 2024
Journal: J Transl Med
Title: The role of NAD-dependent deacetylase sirtuin-2 in liver metabolic stress through regulating pyruvate kinase M2 ubiquitination.
Volume: 22
Issue: 1
Pages: 656
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Publication
32366925 | J:293840
First Author: Rajala A
Year: 2020
Journal: Sci Rep
Title: Metabolic and Non-metabolic Roles of Pyruvate Kinase M2 Isoform in Diabetic Retinopathy.
Volume: 10
Issue: 1
Pages: 7456
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Publication
28436957 | J:250665
First Author: Qi W
Year: 2017
Journal: Nat Med
Title: Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.
Volume: 23
Issue: 6
Pages: 753-762
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Publication
32101747 | J:287616
First Author: Das Gupta K
Year: 2020
Journal: Cell Rep
Title: Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2.
Volume: 30
Issue: 8
Pages: 2712-2728.e8
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Publication
31480861 | J:290401
First Author: Yang J
Year: 2019
Journal: FASEB J
Title: T-cell-derived extracellular vesicles regulate B-cell IgG production via pyruvate kinase muscle isozyme 2.
Volume: 33
Issue: 11
Pages: 12780-12799
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Publication
29732501 | J:350748
First Author: Lü S
Year: 2018
Journal: J Mol Med (Berl)
Title: PKM2-dependent metabolic reprogramming in CD4(+) T cells is crucial for hyperhomocysteinemia-accelerated atherosclerosis.
Volume: 96
Issue: 6
Pages: 585-600
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Publication
31652947 | J:288020
 
First Author: Xie C
Year: 2019
Journal: Cells
Title: Off-Target Deletion of Conditional Dbc1 Allele in the Foxp3YFP-Cre Mouse Line under Specific Setting.
Volume: 8
Issue: 11
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Publication
36848232 | J:334981
First Author: Aguiar CF
Year: 2023
Journal: Cell Rep
Title: Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury.
Volume: 42
Issue: 1
Pages: 112035
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Publication
35997256 | J:328491
   
First Author: Foster HR
Year: 2022
Journal: Elife
Title: β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the KATP channel.
Volume: 11
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Publication
29445082 | J:280457
First Author: Rajala A
Year: 2018
Journal: Cell Death Dis
Title: Pyruvate kinase M2 regulates photoreceptor structure, function, and viability.
Volume: 9
Issue: 2
Pages: 240
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Publication
34733164 | J:314156
 
First Author: Liu YZ
Year: 2021
Journal: Front Pharmacol
Title: Pyruvate Kinase M2 Mediates Glycolysis Contributes to Psoriasis by Promoting Keratinocyte Proliferation.
Volume: 12
Pages: 765790
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Publication
752545 | J:6173
First Author: Lalley PA
Year: 1978
Journal: Cytogenet Cell Genet
Title: The genes coding for pyruvate kinase (M2) and mannosephosphate isomerase are linked in man and mouse.
Volume: 22
Issue: 1-6
Pages: 581-4
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Publication
21325052 | J:170478
First Author: Sun Q
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
Volume: 108
Issue: 10
Pages: 4129-34
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Publication
30131339 | J:272897
First Author: Abeywardana T
Year: 2018
Journal: J Biol Chem
Title: CARM1 suppresses de novo serine synthesis by promoting PKM2 activity.
Volume: 293
Issue: 39
Pages: 15290-15303
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Publication
31328803 | J:282048
First Author: Siragusa M
Year: 2019
Journal: EMBO J
Title: Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.
Volume: 38
Issue: 17
Pages: e100938
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Publication
30970216 | J:290667
First Author: Wan L
Year: 2019
Journal: FASEB J
Title: Exosomes from activated hepatic stellate cells contain GLUT1 and PKM2: a role for exosomes in metabolic switch of liver nonparenchymal cells.
Volume: 33
Issue: 7
Pages: 8530-8542
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Publication
- | J:13848
 
First Author: Chasalow F
Year: 1980
Journal: Mouse News Lett
Title: [Pk-3].
Volume: 62
Pages: 73
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Author
Oliveira Brito PKM
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Publication
36799552 | J:354029
 
First Author: Zhou J
Year: 2023
Journal: ASN Neuro
Title: Pyruvate Kinase 2, an Energy Metabolism Related Enzyme, May Have a Neuroprotective Function in Retinal Degeneration.
Volume: 15
Pages: 17590914231151534
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Publication
30487609 | J:269368
First Author: Zhou HL
Year: 2019
Journal: Nature
Title: Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.
Volume: 565
Issue: 7737
Pages: 96-100
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Publication
30409900 | J:274722
First Author: Fu J
Year: 2019
Journal: J Biol Chem
Title: Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus.
Volume: 294
Issue: 1
Pages: 327-340
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Publication
34879266 | J:321535
First Author: Han J
Year: 2021
Journal: Cell Rep
Title: Aberrant role of pyruvate kinase M2 in the regulation of gamma-secretase and memory deficits in Alzheimer's disease.
Volume: 37
Issue: 10
Pages: 110102
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Publication
36577385 | J:340918
First Author: Veras FP
Year: 2022
Journal: Cell Rep
Title: Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation.
Volume: 41
Issue: 13
Pages: 111897
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Publication
32342224 | J:300802
First Author: Zhang E
Year: 2020
Journal: Mamm Genome
Title: PKM2 ablation enhanced retinal function and survival in a preclinical model of retinitis pigmentosa.
Volume: 31
Issue: 3-4
Pages: 77-85
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Publication
35584006 | J:326292
First Author: Davidson SM
Year: 2022
Journal: Cancer Res
Title: Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
Volume: 82
Issue: 13
Pages: 2403-2416
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Publication
34408323 | J:325771
First Author: Taylor SR
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