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Search results 301 to 400 out of 406 for Plk2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_05
Specimen Label: euxassay_015918_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_06
Specimen Label: euxassay_015918_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_07
Specimen Label: euxassay_015918_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_14
Specimen Label: euxassay_015918_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_15
Specimen Label: euxassay_015918_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_16
Specimen Label: euxassay_015918_16
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_17
Specimen Label: euxassay_015918_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_18
Specimen Label: euxassay_015918_18
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_19
Specimen Label: euxassay_015918_19
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827274
Age: embryonic day 14.5
Image: euxassay_015918_20
Specimen Label: euxassay_015918_20
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422693
Age: embryonic day 14.5
Image: ES3018; Specimen S1058
Note: Expression was strong in the skull (base and vault).
Specimen Label: ES3018; Specimen S1058
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4428697
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422693
Age: embryonic day 14.5
Image: ES3018; Specimen S1058
Note: Expression was strong in whisker follicle.
Specimen Label: ES3018; Specimen S1058
Detected: true
Specimen Num: 1
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HT Experiment
E-GEOD-50003 | Gene Expression Profiling for Plk2 -/- mammary gland
Series Id: GSE50003
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
27623146 | J:237940
   
First Author: Walkup WG
Year: 2016
Journal: Elife
Title: A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density.
Volume: 5
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Publication
22854038 | J:199766
First Author: Jordan PW
Year: 2012
Journal: J Cell Sci
Title: Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes.
Volume: 125
Issue: Pt 21
Pages: 5061-72
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Publication
28698371 | J:244087
First Author: Stopp S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development.
Volume: 114
Issue: 30
Pages: 8029-8034
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Publication
34963132 | J:328712
First Author: Du H
Year: 2022
Journal: Cereb Cortex
Title: Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons.
Volume: 32
Issue: 17
Pages: 3611-3632
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Publication
31569049 | J:306873
 
First Author: Li L
Year: 2019
Journal: iScience
Title: Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells.
Volume: 20
Pages: 148-167
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Publication
26949938 | J:249145
First Author: Goetz JJ
Year: 2016
Journal: PLoS One
Title: Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.
Volume: 11
Issue: 3
Pages: e0150878
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
P53351
Organism: Mus musculus/domesticus
Length: 682  
Fragment?: false
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Publication
12651910 | -
First Author: Ma S
Year: 2003
Journal: Mol Cancer Res
Title: The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB.
Volume: 1
Issue: 5
Pages: 376-84
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UniProt Feature
UniProt Feature
Begin: 583
Description: Phosphoserine; by PLK2
Type: modified residue
End: 583
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UniProt Feature
UniProt Feature
Begin: 577
Description: Phosphoserine; by PLK2
Type: modified residue
End: 577
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase PLK2
Type: chain
End: 682
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UniProt Feature
UniProt Feature
Begin: 129
Description: Phosphoserine; by PLK2
Type: modified residue
End: 129
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UniProt Feature
UniProt Feature
Begin: 581
Description: Phosphoserine; by PLK2
Type: modified residue
End: 581
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UniProt Feature
UniProt Feature
Begin: 71
Description: Phosphoserine; by PLK2
Type: modified residue
End: 71
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UniProt Feature
UniProt Feature
Begin: 617
Description: Phosphoserine; by PLK2
Type: modified residue
End: 617
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UniProt Feature
UniProt Feature
Begin: 766
Description: Phosphoserine; by PLK2
Type: modified residue
End: 766
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UniProt Feature
UniProt Feature
Begin: 1305
Description: Phosphoserine; by PLK2
Type: modified residue
End: 1305
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UniProt Feature
UniProt Feature
Begin: 1309
Description: Phosphothreonine; by PLK2
Type: modified residue
End: 1309
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UniProt Feature
UniProt Feature
Begin: 644
Description: Phosphothreonine; by PLK2
Type: modified residue
End: 644
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UniProt Feature
UniProt Feature
Begin: 933
Description: Phosphoserine; by PLK2
Type: modified residue
End: 933
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UniProt Feature
UniProt Feature
Begin: 806
Description: Phosphoserine; by PLK2
Type: modified residue
End: 806
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UniProt Feature
UniProt Feature
Begin: 1022
Description: Phosphoserine; by PLK2
Type: modified residue
End: 1022
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UniProt Feature
UniProt Feature
Begin: 1175
Description: Phosphoserine; by PLK2
Type: modified residue
End: 1175
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UniProt Feature
UniProt Feature
Begin: 840
Description: Phosphoserine; by PLK2
Type: modified residue
End: 840
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UniProt Feature
UniProt Feature
Begin: 836
Description: Phosphoserine; by PLK2
Type: modified residue
End: 836
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UniProt Feature
UniProt Feature
Begin: 842
Description: Phosphoserine; by PLK2
Type: modified residue
End: 842
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UniProt Feature
UniProt Feature
Begin: 466
Description: Phosphoserine; by PLK2
Type: modified residue
End: 466
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UniProt Feature
UniProt Feature
Begin: 379
Description: Phosphoserine; by PLK2
Type: modified residue
End: 379
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UniProt Feature
UniProt Feature
Begin: 449
Description: Phosphoserine; by PLK2
Type: modified residue
End: 449
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UniProt Feature
UniProt Feature
Begin: 385
Description: Phosphoserine; by PLK2
Type: modified residue
End: 385
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Publication
39498012 | J:359220
First Author: Martínez-Drudis L
Year: 2024
Journal: Heliyon
Title: Pharmacological inhibition of PLK2 kinase activity mitigates cognitive decline but aggravates APP pathology in a sex-dependent manner in APP/PS1 mouse model of Alzheimer's disease.
Volume: 10
Issue: 20
Pages: e39571
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UniProt Feature
UniProt Feature
Begin: 4
Description: Phosphoserine; by PLK1 and PLK2
Type: modified residue
End: 4
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UniProt Feature
UniProt Feature
Begin: 718
Description: Phosphoserine; by PLK2 and PLK3
Type: modified residue
End: 718
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Publication
20531387 | -
First Author: Chang J
Year: 2010
Journal: EMBO J
Title: PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle.
Volume: 29
Issue: 14
Pages: 2395-406
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Publication
22214663 | -
First Author: Haupt S
Year: 2012
Journal: Cell Cycle
Title: Mutant p53 subverts PLK2 function in a novel, reinforced loop of corruption.
Volume: 11
Issue: 2
Pages: 217-8
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Publication
20054236 | -
First Author: Matthew EM
Year: 2009
Journal: Cell Cycle
Title: The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions.
Volume: 8
Issue: 24
Pages: 4168-75
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Allele
Tg(Plk2-EGFP)LM123Gsat | MGI:4847321
Name: transgene insertion LM123, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5004160 | STOCK Tg(Plk2-EGFP)LM123Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Protein Domain
IPR033695 | POLO_box_2
Type: Domain
Description: The polo-like Ser/Thr kinases (Plk1, Plk2/Snk, Plk3/Prk/Fnk, Plk4/Sak, and the inactive kinase Plk5) play various roles in cytokinesis and mitosis. At their C terminus, they contain a tandemly repeated polo-box domain (PBD) (in the case of Plk4, a tandem repeat of cryptic PBDs is found in the middle of the protein followed by a C-terminal single repeat), which appears to be involved in autoinhibition and in mediating the subcellular localization. The latter may be controlled via interactions between the polo-box domain and phospho-peptide motifs. The phosphopeptide binding site is formed at the interface between the two tandemly repeated PBDs. The PBDs of Plk4/Sak appear unique in participating in homodimer interactions, though it is not clear whether and how they interact with phosphopeptides [, , , , , ].This entry represents the second polo-box domain found in Plk1, Plk2 and Plk3.
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Publication
20100802 | J:173149
First Author: Andrysik Z
Year: 2010
Journal: Nucleic Acids Res
Title: The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus.
Volume: 38
Issue: 9
Pages: 2931-43
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Publication
17264206 | J:119760
First Author: Zimmerman WC
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Polo-like kinase 3 is required for entry into S phase.
Volume: 104
Issue: 6
Pages: 1847-52
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Publication
24133254 | J:202746
First Author: Mihalas AB
Year: 2013
Journal: J Neurosci
Title: Opposing action of nuclear factor κB and Polo-like kinases determines a homeostatic end point for excitatory synaptic adaptation.
Volume: 33
Issue: 42
Pages: 16490-501
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Publication
32192190 | J:302942
 
First Author: Hong CT
Year: 2020
Journal: Cells
Title: Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling.
Volume: 9
Issue: 3
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Protein
Q3TV29
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Publication
14592974 | -
First Author: Cheng KY
Year: 2003
Journal: EMBO J
Title: The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.
Volume: 22
Issue: 21
Pages: 5757-68
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Publication
20148280 | -
First Author: Park JE
Year: 2010
Journal: Cell Mol Life Sci
Title: Polo-box domain: a versatile mediator of polo-like kinase function.
Volume: 67
Issue: 12
Pages: 1957-70
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•
•
•
•
Publication
19305416 | -
First Author: Archambault V
Year: 2009
Journal: Nat Rev Mol Cell Biol
Title: Polo-like kinases: conservation and divergence in their functions and regulation.
Volume: 10
Issue: 4
Pages: 265-75
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Publication
17188028 | -
First Author: Dai W
Year: 2006
Journal: Mol Cell
Title: Grabbing Plk1 by the PBD.
Volume: 24
Issue: 4
Pages: 489-90
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•
Publication
21654194 | -
First Author: de Cárcer G
Year: 2011
Journal: Cell Cycle
Title: From Plk1 to Plk5: functional evolution of polo-like kinases.
Volume: 10
Issue: 14
Pages: 2255-62
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Publication
15838519 | -
First Author: van Vugt MA
Year: 2005
Journal: Oncogene
Title: Getting in and out of mitosis with Polo-like kinase-1.
Volume: 24
Issue: 17
Pages: 2844-59
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•
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Protein
Q60806
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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•
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•
Protein
Q07832
Organism: Mus musculus/domesticus
Length: 603  
Fragment?: false
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•
•
•
•
Protein
Q3UG81
Organism: Mus musculus/domesticus
Length: 603  
Fragment?: false
•
•
•
•
•
Protein
Q548A9
Organism: Mus musculus/domesticus
Length: 682  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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