| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion HF78, GENSAT Project at Rockefeller University |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion OG1, GENSAT Project at Rockefeller University |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, mutant stock |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Allele |
| Name: |
plexin D1; targeted mutation 1.1, Z Josh Huang |
| Allele Type: |
Targeted |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
plexin D1; targeted mutation 2.1, Z Josh Huang |
| Allele Type: |
Targeted |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
plexin D1; targeted mutation 1.1, Hongkui Zeng |
| Allele Type: |
Targeted |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McDermott JE |
| Year: |
2018 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Class 4 Semaphorins and Plexin-B receptors regulate GABAergic and glutamatergic synapse development in the mammalian hippocampus. |
| Volume: |
92 |
|
| Pages: |
50-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Feiner L |
| Year: |
2001 |
| Journal: |
Development |
| Title: |
Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. |
| Volume: |
128 |
| Issue: |
16 |
| Pages: |
3061-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gonthier B |
| Year: |
2007 |
| Journal: |
Cereb Cortex |
| Title: |
Functional interaction between matrix metalloproteinase-3 and semaphorin-3C during cortical axonal growth and guidance. |
| Volume: |
17 |
| Issue: |
7 |
| Pages: |
1712-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ko JA |
| Year: |
2005 |
| Journal: |
FEBS Lett |
| Title: |
Requirement of the transmembrane semaphorin Sema4C for myogenic differentiation. |
| Volume: |
579 |
| Issue: |
10 |
| Pages: |
2236-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu H |
| Year: |
2007 |
| Journal: |
Eur J Cell Biol |
| Title: |
Sema4C participates in myogenic differentiation in vivo and in vitro through the p38 MAPK pathway. |
| Volume: |
86 |
| Issue: |
6 |
| Pages: |
331-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vodrazka P |
| Year: |
2009 |
| Journal: |
Eur J Neurosci |
| Title: |
The semaphorin 4D-plexin-B signalling complex regulates dendritic and axonal complexity in developing neurons via diverse pathways. |
| Volume: |
30 |
| Issue: |
7 |
| Pages: |
1193-208 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pasterkamp RJ |
| Year: |
2003 |
| Journal: |
Nature |
| Title: |
Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. |
| Volume: |
424 |
| Issue: |
6947 |
| Pages: |
398-405 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki K |
| Year: |
2007 |
| Journal: |
Nature |
| Title: |
Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. |
| Volume: |
446 |
| Issue: |
7136 |
| Pages: |
680-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Basile JR |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway. |
| Volume: |
25 |
| Issue: |
16 |
| Pages: |
6889-98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Scott GA |
| Year: |
2008 |
| Journal: |
J Invest Dermatol |
| Title: |
Semaphorin 7a promotes spreading and dendricity in human melanocytes through beta1-integrins. |
| Volume: |
128 |
| Issue: |
1 |
| Pages: |
151-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsuruma K |
| Year: |
2012 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
SEMA4A mutations lead to susceptibility to light irradiation, oxidative stress, and ER stress in retinal pigment epithelial cells. |
| Volume: |
53 |
| Issue: |
10 |
| Pages: |
6729-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hall KT |
| Year: |
1996 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation. |
| Volume: |
93 |
| Issue: |
21 |
| Pages: |
11780-5 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This immunoglobulin-like (Ig-like) domain is found in human Semaphorin-3/4/7A (SEMA3/4/7A) and similar sequences. SEMA3F may play a role in cell motility and cell adhesion. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signalling []and it also regulates glutamatergic and GABAergic synapse development []. SEMA7A plays an important role in integrin-mediated signalling and functions both in regulating cell migration and immune responses. It promotes formation of focal adhesion complexes, axon growth in the embryonic olfactory bulb and attachment, spreading and dendrite outgrowth in melanocytes [, , ]. |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Plxnd1-cre)OG1Gsat/? |
| Background: |
involves: 129S4/SvJaeSor * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
L?pez-Mengual A |
| Year: |
2022 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Involvement of Mechanical Cues in the Migration of Cajal-Retzius Cells in the Marginal Zone During Neocortical Development. |
| Volume: |
10 |
|
| Pages: |
886110 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Janssen BJ |
| Year: |
2010 |
| Journal: |
Nature |
| Title: |
Structural basis of semaphorin-plexin signalling. |
| Volume: |
467 |
| Issue: |
7319 |
| Pages: |
1118-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smith JB |
| Year: |
2016 |
| Journal: |
Neuron |
| Title: |
Genetic-Based Dissection Unveils the Inputs and Outputs of Striatal Patch and Matrix Compartments. |
| Volume: |
91 |
| Issue: |
5 |
| Pages: |
1069-1084 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
823
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
823
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
760
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
628
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
861
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
834
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
664
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
837
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
755
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
799
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
785
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
751
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ding SL |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis. |
| Volume: |
31 |
| Issue: |
7 |
| Pages: |
107648 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sugino K |
| Year: |
2019 |
| Journal: |
Elife |
| Title: |
Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain. |
| Volume: |
8 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerfen CR |
| Year: |
2013 |
| Journal: |
Neuron |
| Title: |
GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. |
| Volume: |
80 |
| Issue: |
6 |
| Pages: |
1368-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harris JA |
| Year: |
2019 |
| Journal: |
Nature |
| Title: |
Hierarchical organization of cortical and thalamic connectivity. |
| Volume: |
575 |
| Issue: |
7781 |
| Pages: |
195-202 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Q |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
Regional and cell-type-specific afferent and efferent projections of the mouse claustrum. |
| Volume: |
42 |
| Issue: |
2 |
| Pages: |
112118 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cuoco JA |
| Year: |
2018 |
| Journal: |
Cerebellum |
| Title: |
Malformation of the Posterior Cerebellar Vermis Is a Common Neuroanatomical Phenotype of Genetically Engineered Mice on the C57BL/6 Background. |
| Volume: |
17 |
| Issue: |
2 |
| Pages: |
173-190 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harris JA |
| Year: |
2014 |
| Journal: |
Front Neural Circuits |
| Title: |
Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. |
| Volume: |
8 |
|
| Pages: |
76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
| Year: |
2005 |
| Journal: |
Database Download |
| Title: |
MGI download of GENSAT transgene data |
|
|
|
|
•
•
•
•
•
|