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Search results 301 to 400 out of 427 for Pmp22

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Type Details Score
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
16326107 | J:129218
First Author: Fortun J
Year: 2006
Journal: Neurobiol Dis
Title: Alterations in degradative pathways and protein aggregation in a neuropathy model based on PMP22 overexpression.
Volume: 22
Issue: 1
Pages: 153-64
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Strain
MGI:5297931 | C3H.C-Pmp22<Tr-1H>/H
Attribute String: mutant strain, congenic, chemically induced mutation
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Publication
29202483 | J:258840
First Author: Zhao HT
Year: 2018
Journal: J Clin Invest
Title: PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models.
Volume: 128
Issue: 1
Pages: 359-368
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Gene
292949 | Perp
Type: gene
Organism: rat
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Gene
476218 | PERP
Type: gene
Organism: dog, domestic
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Gene
463027 | PERP
Type: gene
Organism: chimpanzee
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Gene
509485 | PERP
Type: gene
Organism: cattle
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Gene
421682 | PERPB
Type: gene
Organism: chicken
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Gene
421683 | PERPA
Type: gene
Organism: chicken
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Gene
494479 | perp
Type: gene
Organism: zebrafish
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Gene
703890 | PERP
Type: gene
Organism: macaque, rhesus
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Protein
P42925
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Strain
MGI:5297930 | C3H.C-Pmp22<Tr-2H>/H
Attribute String: congenic, chemically induced mutation, mutant strain
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Publication
9467003 | J:77330
First Author: Huxley C
Year: 1998
Journal: Hum Mol Genet
Title: Correlation between varying levels of PMP22 expression and the degree of demyelination and reduction in nerve conduction velocity in transgenic mice.
Volume: 7
Issue: 3
Pages: 449-58
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HT Experiment
E-GEOD-1947 | Transcription profiling of mouse at ages P4 and P60 in sciatic nerve of wild type and with peripheral neuropathies to study disease mechanisms in peripheral neuropathies due to altered Pmp22 gene dosage or a Pmp22 point mutation
Series Id: GSE1947
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
10586248 | J:59849
 
First Author: Anderson TJ
Year: 1999
Journal: Ann N Y Acad Sci
Title: Distinct phenotypes associated with increasing dosage of the PLP gene: implications for CMT1A due to PMP22 gene duplication.
Volume: 883
Pages: 234-46
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Protein Coding Gene
MGI:107487 | Pxmp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Pmp22<em1Smoc> | MGI:7291737
Name: peripheral myelin protein 22; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein
Q9JJG6
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: false
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Protein Domain
IPR015664 | P53_induced
Type: Family
Description: This entry includes p53-induced proteins that are members of the Pmp22 family of tetraspan membrane proteins.
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Allele
Pmp22<tm1Ueli> | MGI:2447704
Name: peripheral myelin protein 22; targeted mutation 1, Ueli Suter
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pmp22<tm1Lnot> | MGI:3614822
Name: peripheral myelin protein 22; targeted mutation 1, Lucia Notterpek
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tg(Pmp22)247Ueli | MGI:2183755
Name: transgene insertion 247, Ueli Suter
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6476052 | C57BL/6JSmoc-Pmp22<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Pmp22<Tr-2H> | MGI:1862011
 
Name: peripheral myelin protein 22; trembler 2 Harwell
Allele Type: Chemically induced (ENU)
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Allele
Tg(tetO/CMV-Pmp22)JP18Clh | MGI:5779548
Name: transgene insertion JP18, Clare Huxley
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Publication
9126480 | -
First Author: Chen Y
Year: 1997
Journal: Genomics
Title: cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family.
Volume: 41
Issue: 1
Pages: 40-8
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Genotype
Genotype
Symbol: Pmp22/Pmp22<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pmp22/Pmp22
Background: involves: 129S/SvEv
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060843 | hereditary neuropathy with liability to pressure palsies
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Strain
MGI:5779553 | B6CBCa-Tg(tetO/CMV-Pmp22)JP18Clh/H
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Tg(Pmp22)247Ueli/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pmp22/Pmp22<+>
Background: involves: BALB/cAnNCrl * C3H/HeN
Zygosity: ht
Has Mutant Allele: true
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Publication
18655835 | J:140352
First Author: Rangaraju S
Year: 2008
Journal: Neurobiol Dis
Title: Pharmacological induction of the heat shock response improves myelination in a neuropathic model.
Volume: 32
Issue: 1
Pages: 105-15
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Publication
12573712 | J:128818
First Author: Norreel JC
Year: 2003
Journal: Neuroscience
Title: Close relationship between motor impairments and loss of functional motoneurons in a Charcot-Marie-Tooth type 1A model.
Volume: 116
Issue: 3
Pages: 695-703
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Publication
11328356 | J:127856
First Author: Norreel JC
Year: 2001
Journal: Eur J Neurosci
Title: Behavioural profiling of a murine Charcot-Marie-Tooth disease type 1A model.
Volume: 13
Issue: 8
Pages: 1625-34
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Publication
31138995 | J:278135
First Author: Lee JS
Year: 2019
Journal: Exp Neurobiol
Title: miR-381 Attenuates Peripheral Neuropathic Phenotype Caused by Overexpression of PMP22.
Volume: 28
Issue: 2
Pages: 279-288
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Publication
20064611 | J:159936
First Author: Kohl B
Year: 2010
Journal: Neurobiol Dis
Title: Lack of evidence for a pathogenic role of T-lymphocytes in an animal model for Charcot-Marie-Tooth disease 1A.
Volume: 38
Issue: 1
Pages: 78-84
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Allele
Pmp22<Tr-2J> | MGI:5515890
 
Name: peripheral myelin protein 22; trembler 2 Jackson
Allele Type: Spontaneous
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Allele
Tg(Pmp22)My41Clh | MGI:2183742
Name: transgene insertion My41, Clare Huxley
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(PMP22)C61Clh | MGI:4819405
Name: transgene insertion C61, Clare Huxley
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(PMP22-tTA)JY13Clh | MGI:5779547
Name: transgene insertion JY13, Clare Huxley
Allele Type: Transgenic
Attribute String: Transactivator
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Publication
8733121 | J:78221
First Author: Huxley C
Year: 1996
Journal: Hum Mol Genet
Title: Construction of a mouse model of Charcot-Marie-Tooth disease type 1A by pronuclear injection of human YAC DNA.
Volume: 5
Issue: 5
Pages: 563-9
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Publication
11327696 | J:69263
First Author: Iida R
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Cloning, mapping, genomic organization, and expression of mouse M-LP, a new member of the peroxisomal membrane protein Mpv17 domain family.
Volume: 283
Issue: 2
Pages: 292-6
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Protein
Q99MS3
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Protein
Q8VIK2
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
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Publication
26760297 | J:232347
First Author: Dalla Rosa I
Year: 2016
Journal: PLoS Genet
Title: MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria.
Volume: 12
Issue: 1
Pages: e1005779
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Protein
P19258
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: false
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Protein
G3UVW1
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
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Protein
E9Q1I6
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: false
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Protein
A0A0J9YVC7
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
D3Z6M3
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: false
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Protein
F8WHT5
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
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Protein
D3YWI4
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: false
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Protein
D6RHR1
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
D3YXY8
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
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Protein
E9Q4P9
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: false
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Protein
Q5D073
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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Publication
11590176 | -
First Author: Brosius U
Year: 2002
Journal: J Biol Chem
Title: Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes.
Volume: 277
Issue: 1
Pages: 774-84
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Publication
15189984 | -
First Author: Trott A
Year: 2004
Journal: Eukaryot Cell
Title: SYM1 is the stress-induced Saccharomyces cerevisiae ortholog of the mammalian kidney disease gene Mpv17 and is required for ethanol metabolism and tolerance during heat shock.
Volume: 3
Issue: 3
Pages: 620-31
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Publication
18227279 | -
First Author: Liu F
Year: 2008
Journal: J Cell Biol
Title: Making two organelles from one: Woronin body biogenesis by peroxisomal protein sorting.
Volume: 180
Issue: 2
Pages: 325-39
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Protein Domain
IPR007248 | Mpv17_PMP22
Type: Family
Description: The 22kDa peroxisomal membrane protein (PMP22) is a major component of peroxisomal membranes. PMP22 seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the organelle membrane. PMP22 is synthesised on free cytosolic ribosomes and then directed to the peroxisome membrane by specific targeting information []. SYM1 in yeast and Mpv17 in higher eukaryotes are closely related peroxisomal proteins required to maintain mitochondrial DNA (mtDNA) integrity and stability [, ]. Mpv17 is involved in the development of early-onset glomerulosclerosis [].Woronin sorting complex protein from Neurospora crassa is also included in this family. It is involved in both Woronin bodies (WB) formation and inherence [].
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Protein
Q9JK95
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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Publication
22940629 | J:316585
 
First Author: Kinter J
Year: 2013
Journal: Neurobiol Dis
Title: An essential role of MAG in mediating axon-myelin attachment in Charcot-Marie-Tooth 1A disease.
Volume: 49
Pages: 221-31
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Publication
37143322 | J:359629
First Author: Jeon H
Year: 2023
Journal: Brain
Title: TGFβ4 alleviates the phenotype of Charcot-Marie-Tooth disease type 1A.
Volume: 146
Issue: 9
Pages: 3608-3615
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Publication
21487305 | J:237901
First Author: Verhamme C
Year: 2011
Journal: J Neuropathol Exp Neurol
Title: Myelin and axon pathology in a long-term study of PMP22-overexpressing mice.
Volume: 70
Issue: 5
Pages: 386-98
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Genotype
Genotype
Symbol: Pmp22/Pmp22<+>
Background: C57BL/6J-Pmp22/GrsrJ
Zygosity: ht
Has Mutant Allele: true
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Allele
Tg(PMP22)C1Clh | MGI:2183769
Name: transgene insertion C1, Clare Huxley
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(PMP22)C22Clh | MGI:2183770
Name: transgene insertion C22, Clare Huxley
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:4819539 | B6.Cg-Tg(PMP22)C61Clh
Attribute String: congenic, mutant strain, transgenic
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Publication
30072689 | J:266312
First Author: Fledrich R
Year: 2018
Journal: Nat Commun
Title: Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy.
Volume: 9
Issue: 1
Pages: 3025
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Allele
Tg(PMP22)C22Fbas | MGI:5817407
Name: transgene insertion C22, Frank Baas
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:5824744 | B6.Cg-Tg(PMP22)C22Fbas
Attribute String: transgenic, mutant strain, congenic
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Allele
Tg(PMP22)C3Fbas | MGI:5817396
Name: transgene insertion C3, Frank Baas
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(PMP22)C61Clh/?
Background: B6.Cg-Tg(PMP22)C61Clh
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pmp22)My41Clh/?
Background: involves: C57BL/6J * CBA/Ca
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(PMP22)C22Fbas/?
Background: B6.Cg-Tg(PMP22)C22Fbas
Zygosity: ot
Has Mutant Allele: true
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Publication
35501630 | J:338996
First Author: Bai Y
Year: 2022
Journal: Mol Neurobiol
Title: Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice.
Volume: 59
Issue: 7
Pages: 4159-4178
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Publication
18835269 | J:141439
First Author: Kaya F
Year: 2008
Journal: FEBS Lett
Title: Ascorbic acid is a regulator of the intracellular cAMP concentration: old molecule, new functions?
Volume: 582
Issue: 25-26
Pages: 3614-8
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Publication
35188681 | J:337602
First Author: Klein D
Year: 2022
Journal: Glia
Title: Early targeting of endoneurial macrophages alleviates the neuropathy and affects abnormal Schwann cell differentiation in a mouse model of Charcot-Marie-Tooth 1A.
Volume: 70
Issue: 6
Pages: 1100-1116
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Strain
MGI:5316388 | B6;CBACa-Tg(PMP22)C22Clh/H
Attribute String: transgenic, mutant stock
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Publication
20830809 | J:167409
First Author: Grimal S
Year: 2010
Journal: Glia
Title: Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells.
Volume: 58
Issue: 16
Pages: 1977-87
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Publication
19111616 | J:146362
First Author: Barbaria EM
Year: 2009
Journal: Neurobiol Dis
Title: The alpha-chemokine CXCL14 is up-regulated in the sciatic nerve of a mouse model of Charcot-Marie-Tooth disease type 1A and alters myelin gene expression in cultured Schwann cells.
Volume: 33
Issue: 3
Pages: 448-58
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Publication
38745059 | J:348313
First Author: Yoon BA
Year: 2024
Journal: Sci Rep
Title: p62/sequestosome-1 as a severity-reflecting plasma biomarker in Charcot-Marie-Tooth disease type 1A.
Volume: 14
Issue: 1
Pages: 10972
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Strain
MGI:5824742 | B6.Cg-Tg(PMP22)C3Fbas
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:7610527 | B6.Cg-Tg(PMP22)C3Fbas/2J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5817411 | B6.Cg-Tg(PMP22)C3Fbas/J
Attribute String: congenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(PMP22)C22Clh/?
Background: involves: C57BL/6J * CBA/Ca
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(PMP22-tTA)JY13Clh/? Tg(tetO/CMV-Pmp22)JP18Clh/?
Background: involves: C57BL/6J * CBA/Ca
Zygosity: cx
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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