| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:1000934 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-07-21 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668822 |
| Pattern: |
Uniform |
| Stage: |
TS22 |
| Assay Id: |
MGI:2666401 |
| Age: |
embryonic day 14.5 |
| Image: |
2310011G23Rik 14.5dpc |
|
| Specimen Label: |
2310011G23Rik 14.5dpc |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821032 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668822 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5421755 |
| Age: |
embryonic day 14.5 |
| Image: |
MY306; Specimen C1577 |
|
| Specimen Label: |
MY306; Specimen C1577 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2664166 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-07-21 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:2666400 |
| Age: |
embryonic day 14.5 |
| Image: |
2310011G23Rik 14.5dpc |
|
| Specimen Label: |
2310011G23Rik 14.5dpc |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1000934 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-07-21 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:2666401 |
| Age: |
embryonic day 14.5 |
| Image: |
2310011G23Rik 14.5dpc |
|
| Specimen Label: |
2310011G23Rik 14.5dpc |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821032 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5421755 |
| Age: |
embryonic day 14.5 |
| Image: |
MY306; Specimen C1577 |
|
| Specimen Label: |
MY306; Specimen C1577 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821032 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757522 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5421755 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
MY306; Specimen C1577 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821032 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1738322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5421755 |
| Age: |
embryonic day 14.5 |
| Image: |
MY306; Specimen C1577 |
|
| Specimen Label: |
MY306; Specimen C1577 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821032 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1802422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5421755 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
MY306; Specimen C1577 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7567447 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-12-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3567622 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7567570 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
2G |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2664166 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689417 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:2666400 |
| Age: |
embryonic day 10.5 |
| Image: |
2310011G23Rik 10.5dpc |
|
| Specimen Label: |
2310011G23Rik 10.5dpc |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1000934 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689417 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:2666401 |
| Age: |
embryonic day 10.5 |
| Image: |
2310011G23Rik 10.5dpc |
|
| Specimen Label: |
2310011G23Rik 10.5dpc |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2664166 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-07-21 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1796222 |
| Pattern: |
Uniform |
| Stage: |
TS22 |
| Assay Id: |
MGI:2666400 |
| Age: |
embryonic day 14.5 |
| Image: |
2310011G23Rik 14.5dpc |
|
| Specimen Label: |
2310011G23Rik 14.5dpc |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1000934 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-07-21 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1796222 |
| Pattern: |
Uniform |
| Stage: |
TS22 |
| Assay Id: |
MGI:2666401 |
| Age: |
embryonic day 14.5 |
| Image: |
2310011G23Rik 14.5dpc |
|
| Specimen Label: |
2310011G23Rik 14.5dpc |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821032 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1768022 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5421755 |
| Age: |
embryonic day 14.5 |
| Image: |
MY306; Specimen C1577 |
| Note: |
Expression was strong in the skull (base and vault). |
| Specimen Label: |
MY306; Specimen C1577 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821032 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2672022 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5421755 |
| Age: |
embryonic day 14.5 |
| Image: |
MY306; Specimen C1577 |
| Note: |
Expression was weak in whisker follicle. |
| Specimen Label: |
MY306; Specimen C1577 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
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BC003494 |
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•
•
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•
•
•
•
•
|
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NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories |
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•
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•
•
•
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•
•
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•
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•
|
| Allele |
| Name: |
protein O-fucosyltransferase 2; targeted mutation 2, Bernadette C Holdener |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready |
|
•
•
•
•
•
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| Allele |
| Name: |
protein O-fucosyltransferase 2; gene trap RST434, BayGenomics |
| Allele Type: |
Gene trapped |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pofut2/Pofut2 |
| Background: |
involves: C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, gene trap |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, gene trap, mutant strain |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein O-fucosyltransferase 2; targeted mutation 2.1, Bernadette C Holdener |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pofut2/Pofut2 |
| Background: |
involves: 129P2/OlaHsd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pofut2/Pofut2<+> |
| Background: |
involves: 129P2/OlaHsd |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
164
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen CI |
| Year: |
2012 |
| Journal: |
EMBO J |
| Title: |
Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O-fucosylation. |
| Volume: |
31 |
| Issue: |
14 |
| Pages: |
3183-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Berardinelli SJ |
| Year: |
2020 |
| Journal: |
Methods Mol Biol |
| Title: |
Analyzing the Effects of O-Fucosylation on Secretion of ADAMTS Proteins Using Cell-Based Assays. |
| Volume: |
2043 |
|
| Pages: |
25-43 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Protein O-fucosylation is a post-translational modification found on serine/threonine residues of thrombospondin type 1 repeats (TSR). The fucose transfer is catalysed by the protein O-fucosyltransferase 2 (POFUT2) []. POFUT2 is required for the proper secretion of ADAMTS (a disintegrin and metalloproteinase with thrombospondin type 1 repeats) family members such as ADAMSL1 and ADAMST13 [, ]. |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein O-fucosyltransferase 2; targeted mutation 2.2, Bernadette C Holdener |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pofut2/Pofut2 |
| Background: |
involves: 129P2/OlaHsd * 129S5/SvEvBrd |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pofut2/Pofut2 |
| Background: |
B6.Cg-Pofut2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pofut2/Pofut2<+> Tg(Prrx1-cre)1Cjt/? |
| Background: |
Not Specified |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
429
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
429
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
168
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
170
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
209
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
429
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang A |
| Year: |
2020 |
| Journal: |
J Biol Chem |
| Title: |
O-Fucosylation of ADAMTSL2 is required for secretion and is impacted by geleophysic dysplasia-causing mutations. |
| Volume: |
295 |
| Issue: |
46 |
| Pages: |
15742-15753 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pofut2/Pofut2 Tg(Prrx1-cre)1Cjt/? |
| Background: |
involves: C57BL/6 * SJL/J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|