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Search results 301 to 400 out of 1214 for Ppara

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Type Details Score
Publication
23704907 | J:200840
First Author: Yang CS
Year: 2013
Journal: PLoS One
Title: Small heterodimer partner-targeting therapy inhibits systemic inflammatory responses through mitochondrial uncoupling protein 2.
Volume: 8
Issue: 5
Pages: e63435
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14656998 | J:119163
First Author: Erol E
Year: 2004
Journal: FASEB J
Title: Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice.
Volume: 18
Issue: 2
Pages: 347-9
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Publication
23238934 | J:194850
First Author: Petrescu AD
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Impact of L-FABP and glucose on polyunsaturated fatty acid induction of PPARα-regulated β-oxidative enzymes.
Volume: 304
Issue: 3
Pages: G241-56
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Publication
29911994 | J:265480
First Author: Seok S
Year: 2018
Journal: J Clin Invest
Title: Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation.
Volume: 128
Issue: 7
Pages: 3144-3159
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Publication
10383430 | J:56079
First Author: Hashimoto T
Year: 1999
Journal: J Biol Chem
Title: Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase. Genotype correlation with fatty liver phenotype.
Volume: 274
Issue: 27
Pages: 19228-36
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Publication
10844002 | J:93972
First Author: Hashimoto T
Year: 2000
Journal: J Biol Chem
Title: Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting.
Volume: 275
Issue: 37
Pages: 28918-28
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Publication
32877213 | J:307085
First Author: Chen X
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: High-fat diet induces fibrosis in mice lacking CYP2A5 and PPARα: a new model for steatohepatitis-associated fibrosis.
Volume: 319
Issue: 5
Pages: G626-G635
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Publication
17466944 | J:121769
First Author: Bedu E
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Double gene deletion reveals the lack of cooperation between PPARalpha and PPARbeta in skeletal muscle.
Volume: 357
Issue: 4
Pages: 877-81
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Publication
28422956 | J:246525
First Author: Jo E
Year: 2017
Journal: PLoS One
Title: Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21.
Volume: 12
Issue: 4
Pages: e0173676
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Publication
18773970 | J:142427
First Author: Martens K
Year: 2008
Journal: Biochim Biophys Acta
Title: Coordinate induction of PPAR alpha and SREBP2 in multifunctional protein 2 deficient mice.
Volume: 1781
Issue: 11-12
Pages: 694-702
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Publication
23747828 | J:202533
First Author: Petrescu AD
Year: 2013
Journal: Biochim Biophys Acta
Title: High glucose potentiates L-FABP mediated fibrate induction of PPARα in mouse hepatocytes.
Volume: 1831
Issue: 8
Pages: 1412-25
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Publication
20045742 | J:164815
First Author: Kang HW
Year: 2010
Journal: Biochim Biophys Acta
Title: Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha).
Volume: 1801
Issue: 4
Pages: 496-502
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Publication
29434210 | J:257697
First Author: Yuan X
Year: 2018
Journal: Nat Commun
Title: Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood.
Volume: 9
Issue: 1
Pages: 636
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Publication
15180999 | J:92232
First Author: Miyazaki M
Year: 2004
Journal: J Biol Chem
Title: Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha.
Volume: 279
Issue: 33
Pages: 35017-24
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Publication
20178979 | J:207597
First Author: Pozzi A
Year: 2010
Journal: J Biol Chem
Title: The anti-tumorigenic properties of peroxisomal proliferator-activated receptor alpha are arachidonic acid epoxygenase-mediated.
Volume: 285
Issue: 17
Pages: 12840-50
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Publication
19320717 | J:147982
First Author: Sehic A
Year: 2009
Journal: Eur J Oral Sci
Title: Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.
Volume: 117
Issue: 2
Pages: 93-104
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Publication
23209793 | J:194781
First Author: Berger JH
Year: 2012
Journal: PLoS One
Title: Major facilitator superfamily domain-containing protein 2a (MFSD2A) has roles in body growth, motor function, and lipid metabolism.
Volume: 7
Issue: 11
Pages: e50629
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Publication
27853148 | J:240649
 
First Author: Quesada-López T
Year: 2016
Journal: Nat Commun
Title: The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes.
Volume: 7
Pages: 13479
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Publication
31451517 | J:280446
First Author: Shao Y
Year: 2019
Journal: Diabetes
Title: A Protective Effect of PPARα in Endothelial Progenitor Cells Through Regulating Metabolism.
Volume: 68
Issue: 11
Pages: 2131-2142
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Publication
16731822 | J:111882
First Author: Lalloyer F
Year: 2006
Journal: Diabetes
Title: Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
Volume: 55
Issue: 6
Pages: 1605-13
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Publication
23104557 | J:194703
First Author: Zhang H
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways.
Volume: 304
Issue: 1
Pages: G72-86
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Publication
21743466 | J:174421
First Author: Sun L
Year: 2011
Journal: Nat Cell Biol
Title: Mir193b-365 is essential for brown fat differentiation.
Volume: 13
Issue: 8
Pages: 958-65
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21325106 | J:172309
First Author: Qiao L
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Energy intake and adiponectin gene expression.
Volume: 300
Issue: 5
Pages: E809-16
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24587793 | J:286505
 
First Author: Vechoropoulos M
Year: 2014
Journal: PPAR Res
Title: The Proatherogenic Effect of Chronic Nitric Oxide Synthesis Inhibition in ApoE-Null Mice Is Dependent on the Presence of PPAR α.
Volume: 2014
Pages: 124583
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Publication
11306606 | J:68880
First Author: Tordjman K
Year: 2001
Journal: J Clin Invest
Title: PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice.
Volume: 107
Issue: 8
Pages: 1025-34
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Publication
17011521 | J:116049
First Author: Sugiyama E
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Haploinsufficiency in the PPARalpha and LDL receptor genes leads to gender- and age-specific obesity and hyperinsulinemia.
Volume: 350
Issue: 2
Pages: 370-6
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Publication
17724261 | J:139843
First Author: Babaev VR
Year: 2007
Journal: Circulation
Title: Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
Volume: 116
Issue: 12
Pages: 1404-12
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Publication
25133427 | J:215910
First Author: Laeger T
Year: 2014
Journal: J Clin Invest
Title: FGF21 is an endocrine signal of protein restriction.
Volume: 124
Issue: 9
Pages: 3913-22
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27610573 | J:236457
First Author: Wang A
Year: 2016
Journal: Cell
Title: Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation.
Volume: 166
Issue: 6
Pages: 1512-1525.e12
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Publication
21326871 | J:170891
First Author: Garrido-Urbani S
Year: 2011
Journal: PLoS One
Title: Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism.
Volume: 6
Issue: 2
Pages: e14665
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Publication
21474829 | J:191472
First Author: Lalloyer F
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice.
Volume: 31
Issue: 7
Pages: 1573-9
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Publication
22989886 | J:314793
First Author: Ghosh A
Year: 2012
Journal: J Biol Chem
Title: Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor α: implications for late infantile Batten disease therapy.
Volume: 287
Issue: 46
Pages: 38922-35
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Publication
30894406 | J:284813
 
First Author: Pierrot N
Year: 2019
Journal: Life Sci Alliance
Title: Sex-regulated gene dosage effect of PPARα on synaptic plasticity.
Volume: 2
Issue: 2
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Publication
17261654 | J:130544
First Author: Duncan JG
Year: 2007
Journal: Circulation
Title: Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.
Volume: 115
Issue: 7
Pages: 909-17
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Publication
37181042 | J:346000
 
First Author: Chougule A
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Osteocytes contribute via nuclear receptor PPAR-alpha to maintenance of bone and systemic energy metabolism.
Volume: 14
Pages: 1145467
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Publication
37580742 | J:339360
First Author: Comerota MM
Year: 2023
Journal: Mol Neurodegener
Title: Oleoylethanolamide facilitates PPARα and TFEB signaling and attenuates Aβ pathology in a mouse model of Alzheimer's disease.
Volume: 18
Issue: 1
Pages: 56
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Publication
32123009 | J:292211
 
First Author: White CJ
Year: 2020
Journal: Mol Cell Biol
Title: Determining the Bioenergetic Capacity for Fatty Acid Oxidation in the Mammalian Nervous System.
Volume: 40
Issue: 10
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Publication
30578827 | J:277511
 
First Author: Chandra S
Year: 2019
Journal: Neurobiol Dis
Title: Cinnamic acid activates PPARα to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model.
Volume: 124
Pages: 379-395
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Publication
31641069 | J:281574
First Author: Cahill LS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis.
Volume: 116
Issue: 45
Pages: 22710-22720
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Publication
15178647 | J:91859
First Author: Yubero P
Year: 2004
Journal: Endocrinology
Title: The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism.
Volume: 145
Issue: 9
Pages: 4268-77
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Publication
21081500 | J:268787
First Author: Im SS
Year: 2011
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor {alpha} is responsible for the up-regulation of hepatic glucose-6-phosphatase gene expression in fasting and db/db Mice.
Volume: 286
Issue: 2
Pages: 1157-64
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Publication
16794006 | J:129548
First Author: Lambert G
Year: 2006
Journal: Endocrinology
Title: Fasting induces hyperlipidemia in mice overexpressing proprotein convertase subtilisin kexin type 9: lack of modulation of very-low-density lipoprotein hepatic output by the low-density lipoprotein receptor.
Volume: 147
Issue: 10
Pages: 4985-95
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Publication
21459324 | J:172247
First Author: Kulozik P
Year: 2011
Journal: Cell Metab
Title: Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.
Volume: 13
Issue: 4
Pages: 389-400
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Publication
25970251 | J:224091
First Author: Lee HY
Year: 2015
Journal: Nature
Title: PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.
Volume: 522
Issue: 7557
Pages: 474-7
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Publication
33229553 | J:299214
First Author: Yueh MF
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease.
Volume: 117
Issue: 49
Pages: 31259-31266
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Publication
20558736 | J:166186
First Author: D'Argenio G
Year: 2010
Journal: J Biol Chem
Title: Colon OCTN2 gene expression is up-regulated by peroxisome proliferator-activated receptor gamma in humans and mice and contributes to local and systemic carnitine homeostasis.
Volume: 285
Issue: 35
Pages: 27078-87
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Publication
18309113 | J:179566
First Author: Fujita K
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha.
Volume: 28
Issue: 5
Pages: 863-70
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Publication
23943624 | J:203962
First Author: Viswakarma N
Year: 2013
Journal: J Biol Chem
Title: The Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase.
Volume: 288
Issue: 39
Pages: 27898-911
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27998724 | J:240187
First Author: Ronis M
Year: 2017
Journal: Am J Pathol
Title: Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis.
Volume: 187
Issue: 2
Pages: 418-430
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25495872 | J:223257
First Author: Patel R
Year: 2015
Journal: Mol Endocrinol
Title: Glucocorticoids regulate the metabolic hormone FGF21 in a feed-forward loop.
Volume: 29
Issue: 2
Pages: 213-23
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37437568 | J:339131
First Author: Paidi RK
Year: 2023
Journal: Cell Rep
Title: Muscle-building supplement β-hydroxy β-methylbutyrate binds to PPARα to improve hippocampal functions in mice.
Volume: 42
Issue: 7
Pages: 112717
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Publication
27982131 | J:250182
 
First Author: Nakagawa Y
Year: 2016
Journal: Sci Rep
Title: CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.
Volume: 6
Pages: 39182
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17550777 | J:129855
First Author: Inagaki T
Year: 2007
Journal: Cell Metab
Title: Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21.
Volume: 5
Issue: 6
Pages: 415-25
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36497130 | J:350517
 
First Author: Yuan T
Year: 2022
Journal: Cells
Title: The Protective Role of Microglial PPARα in Diabetic Retinal Neurodegeneration and Neurovascular Dysfunction.
Volume: 11
Issue: 23
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30866796 | J:274579
First Author: Ruppert PMM
Year: 2019
Journal: BMC Genomics
Title: Transcriptional profiling of PPARα-/- and CREB3L3-/- livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα.
Volume: 20
Issue: 1
Pages: 199
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25501545 | J:223850
First Author: Ronis MJ
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease.
Volume: 308
Issue: 5
Pages: G403-15
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20065164 | J:168445
First Author: Duncan JG
Year: 2010
Journal: Circulation
Title: Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators.
Volume: 121
Issue: 3
Pages: 426-35
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Publication
30898012 | J:297728
First Author: Luo R
Year: 2020
Journal: Autophagy
Title: Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
Volume: 16
Issue: 1
Pages: 52-69
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Publication
28154187 | J:241379
First Author: Vadvalkar SS
Year: 2017
Journal: J Biol Chem
Title: Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic Heart: ROLE OF MITOCHONDRIAL PYRUVATE CARRIER 2 (MPC2) ACETYLATION.
Volume: 292
Issue: 11
Pages: 4423-4433
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16428347 | J:111844
First Author: Durgan DJ
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin.
Volume: 290
Issue: 6
Pages: H2480-97
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Publication
24424044 | J:208810
First Author: Kim H
Year: 2014
Journal: Endocrinology
Title: Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21.
Volume: 155
Issue: 3
Pages: 769-82
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Publication
27301791 | J:272290
 
First Author: Park JG
Year: 2016
Journal: Sci Rep
Title: CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis.
Volume: 6
Pages: 27938
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Publication
35830804 | J:339111
First Author: Dutta D
Year: 2022
Journal: Cell Rep
Title: Treadmill exercise reduces α-synuclein spreading via PPARα.
Volume: 40
Issue: 2
Pages: 111058
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Publication
24496310 | J:212297
First Author: Bonzo JA
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-α function in vivo.
Volume: 306
Issue: 7
Pages: E824-37
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20378851 | J:172706
First Author: Georgiadi A
Year: 2010
Journal: Circ Res
Title: Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress.
Volume: 106
Issue: 11
Pages: 1712-21
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19933841 | J:156389
First Author: Martinez-Jimenez CP
Year: 2010
Journal: Mol Cell Biol
Title: Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.
Volume: 30
Issue: 3
Pages: 565-77
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20972533 | J:169580
First Author: Maida A
Year: 2011
Journal: Diabetologia
Title: Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice.
Volume: 54
Issue: 2
Pages: 339-49
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Publication
16239970 | J:102505
First Author: Gizard F
Year: 2005
Journal: J Clin Invest
Title: PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a.
Volume: 115
Issue: 11
Pages: 3228-38
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Publication
16556735 | J:110937
First Author: Canaple L
Year: 2006
Journal: Mol Endocrinol
Title: Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.
Volume: 20
Issue: 8
Pages: 1715-27
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Publication
19805517 | J:154988
First Author: Sanderson LM
Year: 2009
Journal: Mol Cell Biol
Title: Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.
Volume: 29
Issue: 23
Pages: 6257-67
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Publication
37417957 | J:348904
   
First Author: Masschelin PM
Year: 2023
Journal: Elife
Title: Vitamin B2 enables regulation of fasting glucose availability.
Volume: 12
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31195146 | J:279700
First Author: Xie C
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transport.
Volume: 1864
Issue: 10
Pages: 1396-1411
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Publication
28898698 | J:245528
First Author: Zhang Y
Year: 2017
Journal: Cancer Cell
Title: Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.
Volume: 32
Issue: 3
Pages: 377-391.e9
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22344686 | J:183786
First Author: Chau BN
Year: 2012
Journal: Sci Transl Med
Title: MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Volume: 4
Issue: 121
Pages: 121ra18
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17909121 | J:150243
First Author: Tordjman KM
Year: 2007
Journal: Hypertension
Title: Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse.
Volume: 50
Issue: 5
Pages: 945-51
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16054054 | J:129848
First Author: Finck BN
Year: 2005
Journal: Cell Metab
Title: A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.
Volume: 1
Issue: 2
Pages: 133-44
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Publication
20430893 | J:165365
First Author: Doi R
Year: 2010
Journal: J Biol Chem
Title: CLOCK regulates circadian rhythms of hepatic glycogen synthesis through transcriptional activation of Gys2.
Volume: 285
Issue: 29
Pages: 22114-21
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25773177 | J:220678
First Author: Gao Q
Year: 2015
Journal: Am J Pathol
Title: PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation.
Volume: 185
Issue: 5
Pages: 1396-408
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15505215 | J:93455
First Author: Bäckhed F
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The gut microbiota as an environmental factor that regulates fat storage.
Volume: 101
Issue: 44
Pages: 15718-23
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15456881 | J:93319
First Author: Huss JM
Year: 2004
Journal: Mol Cell Biol
Title: Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle.
Volume: 24
Issue: 20
Pages: 9079-91
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Publication
21383142 | J:170098
First Author: Gachon F
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPARalpha) activity.
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