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Search results 301 to 400 out of 702 for Prkaa2

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313025
Specimen Label: MRC Harwell_1313025
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313023
Specimen Label: MRC Harwell_1313023
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7263095
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7263107
Age: embryonic day 3.5
Specimen Label: 3B control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7263095
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7263107
Age: embryonic day 3.5
Note: Decreased expression compared with the control.
Specimen Label: 3B TallyHO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal day 30
Note: Expression in Purkinje cells and stellate cells of the molecular layer.
Specimen Label: 3C
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal
Note: High expression in Purkinje cells.
Specimen Label: Table 1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3560828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal day 12
Note: Lower expression in glomeruli.
Specimen Label: 4C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3560828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal
Note: High expression in mitral, granule and periglomerular cells.
Specimen Label: Table 1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313031
Specimen Label: MRC Harwell_1313031
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313032
Specimen Label: MRC Harwell_1313032
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7788176
Assay Type: RNA in situ
Annotation Date: 2024-12-18
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1666917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7788365
Age: embryonic day 10.5
Image: 5D control
Specimen Label: 5D control
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:7788176
Assay Type: RNA in situ
Annotation Date: 2024-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666917
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7788365
Age: embryonic day 10.5
Image: 5D Tbx2/3cDKO
Note: Ectopic expression was detected in single cells in the ventral region of the otocyst and the adjacent mesenchyme in the Tbx2/3cDKO.
Specimen Label: 5D Tbx2/3cDKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3560928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal
Note: High expression in mitral, granule and periglomerular cells.
Specimen Label: Table 1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal day 12
Note: High expression in nucleus of all neurons.
Specimen Label: 4C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313022
Specimen Label: MRC Harwell_1313022
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313024
Specimen Label: MRC Harwell_1313024
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal day 30
Note: Expression in neurons in the inferior colliculus.
Specimen Label: 3C
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313032
Specimen Label: MRC Harwell_1313032
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7788176
Assay Type: RNA in situ
Annotation Date: 2024-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1667017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7788365
Age: embryonic day 10.5
Image: 5D Tbx2/3cDKO
Note: Ectopic expression was detected in single cells in the ventral region of the otocyst and the adjacent mesenchyme in the Tbx2/3cDKO.
Specimen Label: 5D Tbx2/3cDKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal day 23
Note: High nuclear expression in all neurons, and cytoplasmic expression in motor neurons and astrocytes.
Specimen Label: 5B
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal
Note: Expression in motor neurons. Not detectable to high expression in astrocytes.
Specimen Label: Table 1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313028
Specimen Label: MRC Harwell_1313028
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313020
Specimen Label: MRC Harwell_1313020
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313021
Specimen Label: MRC Harwell_1313021
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313026
Specimen Label: MRC Harwell_1313026
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal day 30
Note: Lower levels of expression in cerebellar granule cells.
Specimen Label: 3C
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal
Note: Expression in granule cells.
Specimen Label: Table 1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691377
Age: postnatal adult
Image: MRC Harwell_1313027
Specimen Label: MRC Harwell_1313027
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal day 12
Note: Expression in olfactory bulb mitral cells.
Specimen Label: 4C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5698398
Assay Type: Immunohistochemistry
Annotation Date: 2015-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3561128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5698424
Age: postnatal
Note: High expression in mitral, granule and periglomerular cells.
Specimen Label: Table 1
Detected: true
Specimen Num: 5
•
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•
•
•
Publication
30201684 | J:265950
First Author: Geng T
Year: 2018
Journal: Diabetes
Title: H19 lncRNA Promotes Skeletal Muscle Insulin Sensitivity in Part by Targeting AMPK.
Volume: 67
Issue: 11
Pages: 2183-2198
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Publication
24913514 | J:214734
First Author: O'Neill HM
Year: 2014
Journal: Diabetologia
Title: AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice.
Volume: 57
Issue: 8
Pages: 1693-702
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Publication
33186592 | J:331122
 
First Author: Pang ZD
Year: 2021
Journal: Biochem Pharmacol
Title: AMPK upregulates K(Ca)2.3 channels and ameliorates endothelial dysfunction in diet-induced obese mice.
Volume: 183
Pages: 114337
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Publication
34536344 | J:321719
First Author: Zhang XJ
Year: 2021
Journal: Cell Metab
Title: Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species.
Volume: 33
Issue: 10
Pages: 2059-2075.e10
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Publication
30048751 | J:270617
First Author: Wang T
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins.
Volume: 1864
Issue: 10
Pages: 3368-3377
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Publication
23466593 | J:202427
First Author: Demeulder B
Year: 2013
Journal: Biochim Biophys Acta
Title: Differential regulation of eEF2 and p70S6K by AMPKalpha2 in heart.
Volume: 1832
Issue: 6
Pages: 780-90
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Publication
23293026 | J:325719
First Author: Lee JO
Year: 2013
Journal: J Biol Chem
Title: E3 ubiquitin ligase, WWP1, interacts with AMPKα2 and down-regulates its expression in skeletal muscle C2C12 cells.
Volume: 288
Issue: 7
Pages: 4673-80
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Publication
38242911 | J:344957
First Author: Zhang L
Year: 2024
Journal: Sci Rep
Title: AMPKα2 regulates fasting-induced hyperketonemia by suppressing SCOT ubiquitination and degradation.
Volume: 14
Issue: 1
Pages: 1713
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Publication
34077757 | J:319691
First Author: Liu R
Year: 2021
Journal: Mol Cell
Title: Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets.
Volume: 81
Issue: 13
Pages: 2722-2735.e9
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Publication
20299472 | J:169360
First Author: Dong Y
Year: 2010
Journal: Diabetes
Title: Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo.
Volume: 59
Issue: 6
Pages: 1386-96
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Publication
20167927 | J:171036
First Author: Wang S
Year: 2010
Journal: Circ Res
Title: AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes.
Volume: 106
Issue: 6
Pages: 1117-28
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Publication
29408195 | J:257530
 
First Author: Shimizu Y
Year: 2018
Journal: J Mol Cell Cardiol
Title: Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK.
Volume: 116
Pages: 29-40
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Publication
19934006 | J:164158
First Author: Oudit GY
Year: 2010
Journal: Diabetes
Title: Human recombinant ACE2 reduces the progression of diabetic nephropathy.
Volume: 59
Issue: 2
Pages: 529-38
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Publication
31109453 | J:289704
First Author: Wang S
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy.
Volume: 1865
Issue: 7
Pages: 1865-1875
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Publication
32512189 | J:299849
First Author: Gong Y
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Double knockout of Akt2 and AMPK accentuates high fat diet-induced cardiac anomalies through a cGAS-STING-mediated mechanism.
Volume: 1866
Issue: 10
Pages: 165855
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Publication
24295634 | J:207923
 
First Author: Ramamurthy S
Year: 2014
Journal: Neuroscience
Title: AMPK activation regulates neuronal structure in developing hippocampal neurons.
Volume: 259
Pages: 13-24
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Publication
25767884 | J:232919
First Author: Bertoldo MJ
Year: 2015
Journal: PLoS One
Title: Specific deletion of AMP-activated protein kinase (α1AMPK) in murine oocytes alters junctional protein expression and mitochondrial physiology.
Volume: 10
Issue: 3
Pages: e0119680
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Publication
20465544 | J:164464
First Author: Beall C
Year: 2010
Journal: Biochem J
Title: Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.
Volume: 429
Issue: 2
Pages: 323-33
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Publication
29038293 | J:252044
First Author: Hughey CC
Year: 2017
Journal: J Biol Chem
Title: Loss of hepatic AMP-activated protein kinase impedes the rate of glycogenolysis but not gluconeogenic fluxes in exercising mice.
Volume: 292
Issue: 49
Pages: 20125-20140
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Publication
28107516 | J:268879
First Author: Hasenour CM
Year: 2017
Journal: PLoS One
Title: Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation.
Volume: 12
Issue: 1
Pages: e0170382
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Publication
32184359 | J:289831
First Author: Huet C
Year: 2020
Journal: J Biol Chem
Title: Glucose availability but not changes in pancreatic hormones sensitizes hepatic AMPK activity during nutritional transition in rodents.
Volume: 295
Issue: 18
Pages: 5836-5849
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Publication
24403081 | J:209505
First Author: Hasenour CM
Year: 2014
Journal: J Biol Chem
Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo.
Volume: 289
Issue: 9
Pages: 5950-9
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Publication
16567505 | J:108599
First Author: Guigas B
Year: 2006
Journal: Diabetes
Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocation.
Volume: 55
Issue: 4
Pages: 865-74
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Publication
28978947 | J:255398
First Author: Deschemin JC
Year: 2017
Journal: Sci Rep
Title: AMPK is not required for the effect of metformin on the inhibition of BMP6-induced hepcidin gene expression in hepatocytes.
Volume: 7
Issue: 1
Pages: 12679
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Publication
21947382 | J:178126
First Author: Stephenne X
Year: 2011
Journal: Diabetologia
Title: Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status.
Volume: 54
Issue: 12
Pages: 3101-10
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Publication
22233421 | J:184097
First Author: Bultot L
Year: 2012
Journal: Biochem J
Title: AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.
Volume: 443
Issue: 1
Pages: 193-203
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Publication
32213711 | J:312217
First Author: Zimmermann HR
Year: 2020
Journal: J Clin Invest
Title: Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer's model mice.
Volume: 130
Issue: 7
Pages: 3511-3527
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Publication
28882901 | J:253491
First Author: Thomas A
Year: 2017
Journal: Diabetes
Title: Chronic Intermittent Hypoxia Impairs Insulin Sensitivity but Improves Whole-Body Glucose Tolerance by Activating Skeletal Muscle AMPK.
Volume: 66
Issue: 12
Pages: 2942-2951
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Publication
23349504 | J:208558
First Author: Jeppesen J
Year: 2013
Journal: Diabetes
Title: LKB1 regulates lipid oxidation during exercise independently of AMPK.
Volume: 62
Issue: 5
Pages: 1490-9
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Publication
17971451 | J:141571
First Author: Huang J
Year: 2007
Journal: J Biol Chem
Title: Increased glucose disposal and AMP-dependent kinase signaling in a mouse model of hemochromatosis.
Volume: 282
Issue: 52
Pages: 37501-7
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Publication
22727014 | J:187414
First Author: Dagon Y
Year: 2012
Journal: Cell Metab
Title: p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake.
Volume: 16
Issue: 1
Pages: 104-12
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Publication
29928235 | J:337643
 
First Author: MacMillan S
Year: 2018
Journal: Front Physiol
Title: AMPK-α1 or AMPK-α2 Deletion in Smooth Muscles Does Not Affect the Hypoxic Ventilatory Response or Systemic Arterial Blood Pressure Regulation During Hypoxia.
Volume: 9
Pages: 655
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Publication
36028487 | J:327974
First Author: Moral-Sanz J
Year: 2022
Journal: Nat Commun
Title: AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new-born and premature death.
Volume: 13
Issue: 1
Pages: 5034
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Publication
24652947 | J:216537
First Author: Lantier L
Year: 2014
Journal: FASEB J
Title: AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity.
Volume: 28
Issue: 7
Pages: 3211-24
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Publication
20460585 | J:163878
First Author: Lantier L
Year: 2010
Journal: FASEB J
Title: Coordinated maintenance of muscle cell size control by AMP-activated protein kinase.
Volume: 24
Issue: 9
Pages: 3555-61
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Publication
25609422 | J:220997
First Author: Fentz J
Year: 2015
Journal: FASEB J
Title: AMPKα is critical for enhancing skeletal muscle fatty acid utilization during in vivo exercise in mice.
Volume: 29
Issue: 5
Pages: 1725-38
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