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Search results 301 to 400 out of 438 for Psd

0.049s
Type Details Score
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Miranda R
Year: 2009
Journal: Cereb Cortex
Title: Reorganization of inhibitory synapses and increased PSD length of perforated excitatory synapses in hippocampal area CA1 of dystrophin-deficient mdx mice.
Volume: 19
Issue: 4
Pages: 876-88
Publication  
First Author: Sarowar T
Year: 2016
Journal: Mol Brain
Title: Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.
Volume: 9
Pages: 28
Publication  
First Author: Alfieri A
Year: 2017
Journal: Front Mol Neurosci
Title: Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders.
Volume: 10
Pages: 212
GO Term
Publication
First Author: Zieger HL
Year: 2020
Journal: Sci Rep
Title: Disease-associated synaptic scaffold protein CNK2 modulates PSD size and influences localisation of the regulatory kinase TNIK.
Volume: 10
Issue: 1
Pages: 5709
GO Term
GO Term
Publication
First Author: Hung AY
Year: 2008
Journal: J Neurosci
Title: Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.
Volume: 28
Issue: 7
Pages: 1697-708
GO Term
GO Term
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Boeckers TM
Year: 2002
Journal: J Neurochem
Title: ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease.
Volume: 81
Issue: 5
Pages: 903-10
Publication
First Author: Ehlers MD
Year: 1999
Journal: Curr Biol
Title: Synapse structure: glutamate receptors connected by the shanks.
Volume: 9
Issue: 22
Pages: R848-50
Publication  
First Author: Silverman JL
Year: 2011
Journal: Brain Res
Title: Sociability and motor functions in Shank1 mutant mice.
Volume: 1380
Pages: 120-37
Publication
First Author: Wöhr M
Year: 2011
Journal: PLoS One
Title: Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior.
Volume: 6
Issue: 6
Pages: e20631
Publication  
First Author: Sheng M
Year: 2000
Journal: J Cell Sci
Title: The Shank family of scaffold proteins.
Volume: 113 ( Pt 11)
Pages: 1851-6
Protein Domain
Type: Domain
Description: Shank1, also called SSTRIP (Somatostatin receptor-interacting protein), is a brain-specific protein that plays a role in the construction of postsynaptic density (PSD) and the maturation of dendritic spines [, ]. Mice deficient in Shank1 show altered PSD composition, thinner PSDs, smaller dendritic spines, and weaker basal synaptic transmission, although synaptic plasticity is normal. They show increased anxiety and impaired fear memory, but also show better spatial learning [, , ]. A Shank protein carries scaffolding functions through multiple sites of protein-protein interaction in its domain architecture, including ankyrin (ANK) repeats, a long proline rich region, as well as SH3, PDZ, and SAM domains.This entry represents the SH3 domain of Shank1 which binds GRIP, a scaffold protein that binds AMPA receptors and Eph receptors/ligands [].
Publication  
First Author: Folci A
Year: 2016
Journal: Front Mol Neurosci
Title: Myosin IXa Binds AMPAR and Regulates Synaptic Structure, LTP, and Cognitive Function.
Volume: 9
Pages: 1
Publication
First Author: Yoshioka T
Year: 2013
Journal: FEBS Lett
Title: Vangl2, the planar cell polarity protein, is complexed with postsynaptic density protein PSD-95 [corrected].
Volume: 587
Issue: 10
Pages: 1453-9
Publication  
First Author: Sanda M
Year: 2009
Journal: Brain Res
Title: The postsynaptic density protein, IQ-ArfGEF/BRAG1, can interact with IRSp53 through its proline-rich sequence.
Volume: 1251
Pages: 7-15
Protein
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
Publication
First Author: Umekage T
Year: 1991
Journal: FEBS Lett
Title: A mouse brain cDNA encodes a novel protein with the protein kinase C phosphorylation site domain common to MARCKS.
Volume: 286
Issue: 1-2
Pages: 147-51
Protein
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
Publication
First Author: Blackshear PJ
Year: 1993
Journal: J Biol Chem
Title: The MARCKS family of cellular protein kinase C substrates.
Volume: 268
Issue: 3
Pages: 1501-4
Publication
First Author: Thelen M
Year: 1991
Journal: Nature
Title: Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane.
Volume: 351
Issue: 6324
Pages: 320-2
Publication
First Author: Hartwig JH
Year: 1992
Journal: Nature
Title: MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin.
Volume: 356
Issue: 6370
Pages: 618-22
Publication
First Author: Arbuzova A
Year: 2002
Journal: Biochem J
Title: Cross-talk unfolded: MARCKS proteins.
Volume: 362
Issue: Pt 1
Pages: 1-12
Protein Domain
Type: Family
Description: Myristoylated alanine-rich C-kinase substrate (MARCKS) is a predominentcellular substrate for protein kinase C (PKC) that has been implicated in the regulation of brain development, macrophage activation, neuro-secretion and growth factor-dependentmitogenesis [, ]. The N-terminal glycine is the site of myristoylation, which allows effective binding of the protein to the plasma membrane, whereit co-localises with PKC []. MARCKS binds calmodulin in a calcium-dependentmanner; the region responsible for calcium-binding is highly basic, a domainof about 25 amino acids known as the PSD or effector domain, which also contains the PKCphosphorylation sites and has been shown to contribute to membrane binding. When not phosphorylated, the effector domain can bindto filamentous actin []. It is believed that MARCKS may be a regulated crossbridge between actin and the plasma membrane; modulation of the actincross-linking activity by calmodulin and phosphorylation, represent apotential convergence of the calcium-calmodulin and PKC signal transductionpathways in regulation of the actin cytoskeleton. MARCKS also contains an MH2 domain of unknown function.MARCKS-related protein (MRP) is similar to MARCKS in terms of propertiessuch as its myristoylation, phosphorylation and calmodulin-binding, andshares a high degree of sequence similarity. The two regions that show the highestsimilarity are the kinase C phosphorylation site domain and the N-terminalregion containing the myristoylation site []. MARCKS and MRP amino acid compositions are similar, but the alanine content of the latter is lower. MARCKS proteins appear to adopt a native unfolded conformation i.e. as randomly folded chains arranged in non-classical extended conformations, in common with other substrates of PKC.
Publication
First Author: Jordan BA
Year: 2004
Journal: Mol Cell Proteomics
Title: Identification and verification of novel rodent postsynaptic density proteins.
Volume: 3
Issue: 9
Pages: 857-71
Publication  
First Author: Saha S
Year: 2007
Journal: Brain Res
Title: Characterization of mouse neuronal Ca2+/calmodulin kinase II inhibitor alpha.
Volume: 1148
Pages: 38-42
Publication
First Author: Zeng M
Year: 2016
Journal: Cell
Title: Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity.
Volume: 166
Issue: 5
Pages: 1163-1175.e12
Publication
First Author: Mercaldo V
Year: 2023
Journal: Neuron
Title: Altered striatal actin dynamics drives behavioral inflexibility in a mouse model of fragile X syndrome.
Volume: 111
Issue: 11
Pages: 1760-1775.e8
Publication
First Author: Sharma N
Year: 2010
Journal: Neuron
Title: Long-distance control of synapse assembly by target-derived NGF.
Volume: 67
Issue: 3
Pages: 422-34
Publication
First Author: Um JW
Year: 2013
Journal: Neuron
Title: Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein.
Volume: 79
Issue: 5
Pages: 887-902
Publication
First Author: Coba MP
Year: 2018
Journal: Sci Rep
Title: Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability.
Volume: 8
Issue: 1
Pages: 2281
Publication
First Author: Takeuchi T
Year: 2005
Journal: J Neurosci
Title: Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum.
Volume: 25
Issue: 8
Pages: 2146-56
Publication    
First Author: Mastro TL
Year: 2020
Journal: Elife
Title: A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency.
Volume: 9
Publication    
First Author: Walkup WG
Year: 2016
Journal: Elife
Title: A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density.
Volume: 5
Publication
First Author: Sheng N
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes.
Volume: 115
Issue: 15
Pages: 3948-3953
Publication
First Author: Lee SH
Year: 2018
Journal: Nat Commun
Title: Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes.
Volume: 9
Issue: 1
Pages: 3434
Publication
First Author: Distler U
Year: 2014
Journal: Proteomics
Title: In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.
Volume: 14
Issue: 21-22
Pages: 2607-13
Publication
First Author: Lu J
Year: 2007
Journal: Neuron
Title: Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer.
Volume: 55
Issue: 6
Pages: 874-89
Publication
First Author: Hida Y
Year: 2011
Journal: J Biochem
Title: Prickle2 is localized in the postsynaptic density and interacts with PSD-95 and NMDA receptors in the brain.
Volume: 149
Issue: 6
Pages: 693-700
Publication  
First Author: Bayés À
Year: 2017
Journal: Nat Commun
Title: Evolution of complexity in the zebrafish synapse proteome.
Volume: 8
Pages: 14613
Publication
First Author: Li J
Year: 2017
Journal: Nat Neurosci
Title: Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
Volume: 20
Issue: 8
Pages: 1150-1161
Publication
First Author: Okabe S
Year: 2001
Journal: J Neurosci
Title: Rapid redistribution of the postsynaptic density protein PSD-Zip45 (Homer 1c) and its differential regulation by NMDA receptors and calcium channels.
Volume: 21
Issue: 24
Pages: 9561-71
Publication
First Author: Moutin E
Year: 2012
Journal: J Cell Sci
Title: GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity.
Volume: 125
Issue: Pt 8
Pages: 2030-40
Publication
First Author: Fukata Y
Year: 2013
Journal: J Cell Biol
Title: Local palmitoylation cycles define activity-regulated postsynaptic subdomains.
Volume: 202
Issue: 1
Pages: 145-61
Publication  
First Author: Feng Z
Year: 2022
Journal: J Cell Biol
Title: IRSp53 promotes postsynaptic density formation and actin filament bundling.
Volume: 221
Issue: 8
Publication
First Author: Trinidad JC
Year: 2006
Journal: Mol Cell Proteomics
Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Volume: 5
Issue: 5
Pages: 914-22
Publication
First Author: Zhu D
Year: 2015
Journal: J Clin Invest
Title: BAI1 regulates spatial learning and synaptic plasticity in the hippocampus.
Volume: 125
Issue: 4
Pages: 1497-508
Publication
First Author: Carlisle HJ
Year: 2011
Journal: J Neurosci
Title: Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.
Volume: 31
Issue: 45
Pages: 16194-207
Publication
First Author: Parker MJ
Year: 2004
Journal: J Neurosci
Title: PSD93 regulates synaptic stability at neuronal cholinergic synapses.
Volume: 24
Issue: 2
Pages: 378-88
Publication
First Author: Jo K
Year: 1999
Journal: J Neurosci
Title: Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.
Volume: 19
Issue: 11
Pages: 4189-99
Publication
First Author: Schütt J
Year: 2009
Journal: J Biol Chem
Title: Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.
Volume: 284
Issue: 38
Pages: 25479-87
Publication
First Author: Takahashi E
Year: 2010
Journal: J Mol Neurosci
Title: Interaction between Ca(v)2.1alpha (1) and CaMKII in Ca (v)2.1alpha (1) mutant mice, Rolling Nagoya.
Volume: 41
Issue: 2
Pages: 223-9
Publication
First Author: Merino P
Year: 2018
Journal: J Biol Chem
Title: Urokinase-type plasminogen activator (uPA) promotes ezrin-mediated reorganization of the synaptic cytoskeleton in the ischemic brain.
Volume: 293
Issue: 24
Pages: 9234-9247
Publication
First Author: Yoshii A
Year: 2013
Journal: J Neurosci
Title: A Myosin Va mutant mouse with disruptions in glutamate synaptic development and mature plasticity in visual cortex.
Volume: 33
Issue: 19
Pages: 8472-82
Publication  
First Author: Pandian S
Year: 2020
Journal: eNeuro
Title: Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal Synapses.
Volume: 7
Issue: 6
Publication  
First Author: Wu D
Year: 2020
Journal: Brain Behav Immun
Title: Interleukin-18 from neurons and microglia mediates depressive behaviors in mice with post-stroke depression.
Volume: 88
Pages: 411-420
Publication
First Author: Panzanelli P
Year: 2017
Journal: Brain Struct Funct
Title: Differential role of GABAA receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus.
Volume: 222
Issue: 9
Pages: 4149-4161
Publication
First Author: Lin Z
Year: 2021
Journal: J Neurosci
Title: Protein Phosphatase 2B Dual Function Facilitates Synaptic Integrity and Motor Learning.
Volume: 41
Issue: 26
Pages: 5579-5594
Publication  
First Author: Chenaux G
Year: 2016
Journal: eNeuro
Title: Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo.
Volume: 3
Issue: 5
Publication  
First Author: Okuda K
Year: 2017
Journal: Neurobiol Dis
Title: CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility.
Volume: 106
Pages: 158-170
Publication
First Author: Akashi K
Year: 2009
Journal: J Neurosci
Title: NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses.
Volume: 29
Issue: 35
Pages: 10869-82
Publication  
First Author: Xu L
Year: 2017
Journal: Neural Plast
Title: Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.
Volume: 2017
Pages: 3270725
Publication
First Author: Schapitz IU
Year: 2010
Journal: J Neurosci
Title: Neuroligin 1 is dynamically exchanged at postsynaptic sites.
Volume: 30
Issue: 38
Pages: 12733-44
Publication
First Author: Pallas-Bazarra N
Year: 2016
Journal: EMBO J
Title: Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis.
Volume: 35
Issue: 13
Pages: 1417-36
Publication
First Author: Henson MA
Year: 2012
Journal: PLoS One
Title: Genetic deletion of NR3A accelerates glutamatergic synapse maturation.
Volume: 7
Issue: 8
Pages: e42327
Publication  
First Author: Katano T
Year: 2016
Journal: eNeuro
Title: Involvement of Brain-Enriched Guanylate Kinase-Associated Protein (BEGAIN) in Chronic Pain after Peripheral Nerve Injury.
Volume: 3
Issue: 5
Publication  
First Author: Balu DT
Year: 2011
Journal: Brain Res
Title: Glutamate receptor composition of the post-synaptic density is altered in genetic mouse models of NMDA receptor hypo- and hyperfunction.
Volume: 1392
Pages: 1-7
Publication
First Author: Asada-Utsugi M
Year: 2021
Journal: Mol Brain
Title: Mice with cleavage-resistant N-cadherin exhibit synapse anomaly in the hippocampus and outperformance in spatial learning tasks.
Volume: 14
Issue: 1
Pages: 23
Publication
First Author: Yasumura M
Year: 2008
Journal: Neurosci Lett
Title: Role of the internal Shank-binding segment of glutamate receptor delta2 in synaptic localization and cerebellar functions.
Volume: 433
Issue: 2
Pages: 146-51
Publication
First Author: Barnett MW
Year: 2006
Journal: J Neurosci
Title: Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice.
Volume: 26
Issue: 5
Pages: 1355-65
Publication
First Author: Katano T
Year: 2023
Journal: Sci Rep
Title: Brain-enriched guanylate kinase-associated protein, a component of the post-synaptic density protein complexes, contributes to learning and memory.
Volume: 13
Issue: 1
Pages: 22027
Publication
First Author: Kiraly DD
Year: 2011
Journal: J Neurosci
Title: Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Volume: 31
Issue: 35
Pages: 12554-65
Publication
First Author: Sawallisch C
Year: 2009
Journal: J Biol Chem
Title: The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Volume: 284
Issue: 14
Pages: 9225-36
Publication
First Author: Won S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.
Volume: 113
Issue: 32
Pages: E4736-44
Publication
First Author: Tian Y
Year: 2015
Journal: Mol Brain
Title: VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation.
Volume: 8
Issue: 1
Pages: 70
Publication
First Author: Sowers LP
Year: 2013
Journal: Mol Psychiatry
Title: Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction.
Volume: 18
Issue: 10
Pages: 1077-89
Publication  
First Author: Huang M
Year: 2021
Journal: Neurosci Res
Title: Deficiency of SHANK3 isoforms impairs thermal hyperalgesia and dysregulates the expression of postsynaptic proteins in the spinal cord.
Volume: 163
Pages: 26-33
Publication  
First Author: Reim D
Year: 2017
Journal: Front Mol Neurosci
Title: Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder.
Volume: 10
Pages: 26
Publication
First Author: Atanasova E
Year: 2023
Journal: Mol Autism
Title: Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice.
Volume: 14
Issue: 1
Pages: 1
Publication
First Author: Wegner W
Year: 2018
Journal: Sci Rep
Title: In vivo STED microscopy visualizes PSD95 sub-structures and morphological changes over several hours in the mouse visual cortex.
Volume: 8
Issue: 1
Pages: 219
Publication  
First Author: Yamada D
Year: 2022
Journal: Front Immunol
Title: Gain-of-function of TRPM4 predisposes mice to psoriasiform dermatitis.
Volume: 13
Pages: 1025499
Publication
First Author: Trinidad JC
Year: 2005
Journal: J Neurochem
Title: Phosphorylation state of postsynaptic density proteins.
Volume: 92
Issue: 6
Pages: 1306-16
Publication
First Author: Kobayashi C
Year: 2007
Journal: J Comp Neurol
Title: Drebrin a content correlates with spine head size in the adult mouse cerebral cortex.
Volume: 503
Issue: 5
Pages: 618-26