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Search results 301 to 400 out of 3238 for Psen1

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Type Details Score
Publication
28261055 | J:311363
 
First Author: Gardenal E
Year: 2017
Journal: Front Neurosci
Title: Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 11
Pages: 81
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30072874 | J:264919
 
First Author: Piquet J
Year: 2018
Journal: Front Cell Neurosci
Title: Supragranular Pyramidal Cells Exhibit Early Metabolic Alterations in the 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 12
Pages: 216
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Publication
35140584 | J:348535
 
First Author: Javonillo DI
Year: 2021
Journal: Front Neurosci
Title: Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 15
Pages: 785276
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Publication
35994169 | J:348516
First Author: Jensen JH
Year: 2023
Journal: NMR Biomed
Title: Comparison of two types of microscopic diffusion anisotropy in mouse brain.
Volume: 36
Issue: 1
Pages: e4816
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Publication
37597424 | J:340568
 
First Author: He Z
Year: 2023
Journal: Redox Biol
Title: Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through peroxisome proliferator-activated receptor γ-dependent mechanism in Alzheimer's disease.
Volume: 66
Pages: 102848
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Publication
30862541 | J:352867
 
First Author: Chen C
Year: 2019
Journal: Free Radic Biol Med
Title: Low-dose oral copper treatment changes the hippocampal phosphoproteomic profile and perturbs mitochondrial function in a mouse model of Alzheimer's disease.
Volume: 135
Pages: 144-156
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Publication
24990149 | J:215460
First Author: Guedes JR
Year: 2014
Journal: Hum Mol Genet
Title: Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model.
Volume: 23
Issue: 23
Pages: 6286-301
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Publication
32930407 | J:311351
First Author: Xu F
Year: 2021
Journal: J Comp Neurol
Title: Remodeling of projections from ventral hippocampus to prefrontal cortex in Alzheimer's mice.
Volume: 529
Issue: 7
Pages: 1486-1498
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29953929 | J:268198
 
First Author: Frontiñán-Rubio J
Year: 2018
Journal: Mol Cell Neurosci
Title: Sex-dependent co-occurrence of hypoxia and β-amyloid plaques in hippocampus and entorhinal cortex is reversed by long-term treatment with ubiquinol and ascorbic acid in the 3 × Tg-AD mouse model of Alzheimer's disease.
Volume: 92
Pages: 67-81
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Publication
36911262 | J:351753
 
First Author: Lambracht-Washington D
Year: 2023
Journal: Aging Brain
Title: Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy.
Volume: 3
Pages: 100066
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Publication
35053244 | J:324105
 
First Author: Meinicke A
Year: 2022
Journal: Biomolecules
Title: Surfactant Protein-G in Wildtype and 3xTg-AD Mice: Localization in the Forebrain, Age-Dependent Hippocampal Dot-like Deposits and Brain Content.
Volume: 12
Issue: 1
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Publication
21945538 | J:180010
First Author: Overk CR
Year: 2012
Journal: Neurobiol Dis
Title: Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice.
Volume: 45
Issue: 1
Pages: 479-87
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35799540 | J:348307
First Author: Yan F
Year: 2023
Journal: Neural Regen Res
Title: Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice.
Volume: 18
Issue: 1
Pages: 183-188
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Publication
31453805 | J:281731
   
First Author: Yagensky O
Year: 2019
Journal: Elife
Title: Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity.
Volume: 8
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36642814 | J:336275
First Author: Dave N
Year: 2023
Journal: Aging Cell
Title: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks.
Volume: 22
Issue: 2
Pages: e13775
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25092575 | J:218334
 
First Author: Pensalfini A
Year: 2014
Journal: Neurobiol Dis
Title: Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques.
Volume: 71
Pages: 53-61
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21738757 | J:241843
First Author: Chadwick W
Year: 2011
Journal: PLoS One
Title: Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity.
Volume: 6
Issue: 6
Pages: e21660
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21514693 | J:188212
First Author: Yao J
Year: 2012
Journal: Neurobiol Aging
Title: Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid.
Volume: 33
Issue: 8
Pages: 1507-21
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33362678 | J:313469
 
First Author: Kong Y
Year: 2020
Journal: Front Neurol
Title: PET Imaging of Neutrophils Infiltration in Alzheimer's Disease Transgenic Mice.
Volume: 11
Pages: 523798
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29480178 | J:357924
First Author: King JL
Year: 2018
Journal: J Alzheimers Dis
Title: Age-Related Changes in the Spatial Frequency Threshold of Male and Female 3xTg-AD Mice Using OptoMotry.
Volume: 62
Issue: 2
Pages: 591-596
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38238285 | J:347908
First Author: Cho SY
Year: 2024
Journal: Transl Psychiatry
Title: Reconsidering repurposing: long-term metformin treatment impairs cognition in Alzheimer's model mice.
Volume: 14
Issue: 1
Pages: 34
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21803451 | J:188197
First Author: Singh C
Year: 2012
Journal: Neurobiol Aging
Title: Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice.
Volume: 33
Issue: 8
Pages: 1493-506
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20708822 | J:188231
First Author: Gredilla R
Year: 2012
Journal: Neurobiol Aging
Title: Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease.
Volume: 33
Issue: 4
Pages: 694-707
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29844403 | J:351935
First Author: Fan SJ
Year: 2018
Journal: Cell Death Dis
Title: The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer's disease model.
Volume: 9
Issue: 6
Pages: 655
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18603329 | J:159591
First Author: Nakashima AS
Year: 2010
Journal: Neurobiol Aging
Title: Experience-dependent regulation of vesicular zinc in male and female 3xTg-AD mice.
Volume: 31
Issue: 4
Pages: 605-13
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Publication
36116712 | J:348654
 
First Author: Falangola MF
Year: 2022
Journal: Magn Reson Imaging
Title: Brain microstructure abnormalities in the 3xTg-AD mouse - A diffusion MRI and morphology correlation study.
Volume: 94
Pages: 48-55
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Publication
26077803 | J:225742
First Author: Baglietto-Vargas D
Year: 2015
Journal: J Neurochem
Title: Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice.
Volume: 134
Issue: 5
Pages: 915-26
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Publication
37575309 | J:349675
 
First Author: Noel RL
Year: 2023
Journal: Front Neurosci
Title: Getting ahead of Alzheimer's disease: early intervention with focused ultrasound.
Volume: 17
Pages: 1229683
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29141186 | J:257779
 
First Author: Shapira R
Year: 2018
Journal: Neurobiol Aging
Title: Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating neuroinflammation.
Volume: 62
Pages: 105-119
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26876740 | J:230861
 
First Author: Zou J
Year: 2016
Journal: Brain Res
Title: Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease.
Volume: 1637
Pages: 56-63
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20359775 | J:188247
First Author: Knight EM
Year: 2012
Journal: Neurobiol Aging
Title: Hypermetabolism in a triple-transgenic mouse model of Alzheimer's disease.
Volume: 33
Issue: 1
Pages: 187-93
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Publication
25541422 | J:219588
First Author: Scala F
Year: 2015
Journal: Neurobiol Aging
Title: Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3.
Volume: 36
Issue: 2
Pages: 886-900
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Publication
33285637 | J:351954
First Author: Stojakovic A
Year: 2021
Journal: J Alzheimers Dis
Title: Partial Inhibition of Mitochondrial Complex I Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Mice.
Volume: 79
Issue: 1
Pages: 335-353
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Publication
34838667 | J:322616
 
First Author: Lin X
Year: 2022
Journal: Neurobiol Dis
Title: Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model.
Volume: 162
Pages: 105562
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Publication
31065079 | J:279862
First Author: Li G
Year: 2019
Journal: Sci Rep
Title: High-throughput metabolomics and ingenuity pathway approach reveals the pharmacological effect and targets of Ginsenoside Rg1 in Alzheimer's disease mice.
Volume: 9
Issue: 1
Pages: 7040
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Publication
26162480 | J:285086
 
First Author: Martinez-Coria H
Year: 2015
Journal: Brain Res Bull
Title: Repeated cognitive stimulation alleviates memory impairments in an Alzheimer's disease mouse model.
Volume: 117
Pages: 10-5
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Publication
31813629 | J:298321
 
First Author: Bonfili L
Year: 2020
Journal: Neurobiol Aging
Title: Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease.
Volume: 87
Pages: 35-43
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19020010 | J:142370
First Author: Oddo S
Year: 2008
Journal: J Neurosci
Title: Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology.
Volume: 28
Issue: 47
Pages: 12163-75
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Publication
31130848 | J:284316
 
First Author: Sanguinetti E
Year: 2019
Journal: Front Cell Neurosci
Title: Combined Effect of Fatty Diet and Cognitive Decline on Brain Metabolism, Food Intake, Body Weight, and Counteraction by Intranasal Insulin Therapy in 3×Tg Mice.
Volume: 13
Pages: 188
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19705573 | J:153528
First Author: Bourasset F
Year: 2009
Journal: Neuropharmacology
Title: Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease.
Volume: 56
Issue: 4
Pages: 808-13
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Publication
29847796 | J:270730
First Author: Flamier A
Year: 2018
Journal: Cell Rep
Title: Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency.
Volume: 23
Issue: 9
Pages: 2653-2666
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Publication
29068127 | J:351780
First Author: Lin KH
Year: 2018
Journal: Environ Toxicol
Title: The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice.
Volume: 33
Issue: 1
Pages: 83-92
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Publication
29233183 | J:351782
First Author: Hwang KD
Year: 2017
Journal: Mol Brain
Title: Restoring synaptic plasticity and memory in mouse models of Alzheimer's disease by PKR inhibition.
Volume: 10
Issue: 1
Pages: 57
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Publication
29204248 | J:351781
 
First Author: Nie L
Year: 2017
Journal: Oxid Med Cell Longev
Title: Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer's Disease.
Volume: 2017
Pages: 6473506
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Publication
21423579 | J:171702
First Author: Corona C
Year: 2011
Journal: PLoS One
Title: Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice.
Volume: 6
Issue: 3
Pages: e17971
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Publication
32916195 | J:299673
 
First Author: Sarlus H
Year: 2020
Journal: Neuroscience
Title: Chronic Airway Allergy Induces Pro-Inflammatory Responses in the Brain of Wildtype Mice but Not 3xTgAD Mice.
Volume: 448
Pages: 14-27
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Publication
28939860 | J:255393
First Author: Chen L
Year: 2017
Journal: Sci Rep
Title: UbasM: An effective balanced optical clearing method for intact biomedical imaging.
Volume: 7
Issue: 1
Pages: 12218
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Publication
37730113 | J:342071
 
First Author: Wang ZJ
Year: 2023
Journal: Neuropharmacology
Title: Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer's disease via the GLP-1R/SIRT1/GLUT4 pathway.
Volume: 240
Pages: 109716
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Publication
22177720 | J:188318
First Author: García-Mesa Y
Year: 2012
Journal: Neurobiol Aging
Title: Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse.
Volume: 33
Issue: 6
Pages: 1124.e13-29
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Publication
16504943 | J:107582
First Author: Caccamo A
Year: 2006
Journal: Neuron
Title: M1 receptors play a central role in modulating AD-like pathology in transgenic mice.
Volume: 49
Issue: 5
Pages: 671-82
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23312564 | J:284611
First Author: Baglietto-Vargas D
Year: 2013
Journal: Biol Psychiatry
Title: Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.
Volume: 74
Issue: 5
Pages: 357-66
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Publication
38400523 | J:350700
First Author: Liu J
Year: 2024
Journal: FEBS J
Title: Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
Volume: 291
Issue: 10
Pages: 2221-2241
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Publication
30071370 | J:271557
 
First Author: Bourgeois A
Year: 2018
Journal: Neurobiol Aging
Title: Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice.
Volume: 71
Pages: 21-31
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Publication
27173425 | J:249651
First Author: Hayashi-Park E
Year: 2017
Journal: Behav Brain Res
Title: Experimentally induced diabetes worsens neuropathology, but not learning and memory, in middle aged 3xTg mice.
Volume: 322
Issue: Pt B
Pages: 280-287
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Publication
18068923 | J:135291
First Author: Sensi SL
Year: 2008
Journal: Exp Gerontol
Title: Altered oxidant-mediated intraneuronal zinc mobilization in a triple transgenic mouse model of Alzheimer's disease.
Volume: 43
Issue: 5
Pages: 488-92
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Publication
39253611 | J:360716
First Author: Qian K
Year: 2024
Journal: Asian J Pharm Sci
Title: Rational fusion design inspired by cell-penetrating peptide: SS31/S-14 G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease.
Volume: 19
Issue: 4
Pages: 100938
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Publication
35961538 | J:328004
 
First Author: Castillo-Mariqueo L
Year: 2022
Journal: Behav Brain Res
Title: Clasping, ledge-score coordination and early gait impairments as primary behavioural markers of functional impairment in Alzheimer's disease.
Volume: 435
Pages: 114054
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Publication
20505094 | J:160821
First Author: Clinton LK
Year: 2010
Journal: J Neurosci
Title: Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline.
Volume: 30
Issue: 21
Pages: 7281-9
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Publication
24244584 | J:209696
First Author: Ding F
Year: 2013
Journal: PLoS One
Title: Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
Volume: 8
Issue: 11
Pages: e79977
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21951279 | J:178473
First Author: Jung CK
Year: 2011
Journal: J Neurochem
Title: Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo.
Volume: 119
Issue: 5
Pages: 1064-73
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25680266 | J:221905
First Author: Jensen MM
Year: 2015
Journal: Neurobiol Aging
Title: Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease.
Volume: 36
Issue: 4
Pages: 1629-1638
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Publication
37619698 | J:339650
 
First Author: Philipsberg PA
Year: 2023
Journal: Neurosci Lett
Title: Chronotate: An open-source tool for manual timestamping and quantification of animal behavior.
Volume: 814
Pages: 137461
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Publication
35153718 | J:321582
 
First Author: Tureckova J
Year: 2021
Journal: Front Aging Neurosci
Title: Compromised Astrocyte Swelling/Volume Regulation in the Hippocampus of the Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 783120
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Publication
18687504 | J:161837
First Author: Jo DG
Year: 2010
Journal: Neurobiol Aging
Title: Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
Volume: 31
Issue: 6
Pages: 917-25
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Publication
39040060 | J:352150
First Author: Qiao Y
Year: 2024
Journal: iScience
Title: The role of m6A modification in the risk prediction and Notch1 pathway of Alzheimer's disease.
Volume: 27
Issue: 7
Pages: 110235
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Publication
35286012 | J:350790
First Author: Huang CY
Year: 2022
Journal: Environ Toxicol
Title: Edible folic acid and medicinal folinic acid produce cardioprotective effects in late-stage triple-transgenic Alzheimer's disease model mice by suppressing cardiac hypertrophy and fibrosis.
Volume: 37
Issue: 7
Pages: 1740-1749
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Publication
28941799 | J:254181
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
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Publication
24268884 | J:212736
First Author: Shin MK
Year: 2014
Journal: Neurobiol Aging
Title: Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
Volume: 35
Issue: 5
Pages: 990-1001
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Publication
20332427 | J:185414
First Author: Cheung KH
Year: 2010
Journal: Sci Signal
Title: Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.
Volume: 3
Issue: 114
Pages: ra22
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Publication
29760653 | J:324368
 
First Author: Zhang Q
Year: 2018
Journal: Front Mol Neurosci
Title: CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment.
Volume: 11
Pages: 146
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Publication
25446812 | J:223867
 
First Author: Stevens LM
Year: 2015
Journal: Behav Brain Res
Title: Reference and working memory deficits in the 3xTg-AD mouse between 2 and 15-months of age: a cross-sectional study.
Volume: 278
Pages: 496-505
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Publication
36009514 | J:350180
 
First Author: Jullienne A
Year: 2022
Journal: Biomedicines
Title: Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 10
Issue: 8
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20042680 | J:156761
First Author: Martinez-Coria H
Year: 2010
Journal: Am J Pathol
Title: Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice.
Volume: 176
Issue: 2
Pages: 870-80
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36194703 | J:350182
First Author: Walter KR
Year: 2023
Journal: Am J Drug Alcohol Abuse
Title: Prenatal alcohol exposure causes persistent microglial activation and age- and sex- specific effects on cognition and metabolic outcomes in an Alzheimer's Disease mouse model.
Volume: 49
Issue: 3
Pages: 302-320
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Publication
23618870 | J:211732
First Author: Edrey YH
Year: 2013
Journal: Neurobiol Aging
Title: Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease.
Volume: 34
Issue: 10
Pages: 2352-60
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Publication
23155407 | J:195586
First Author: Yan XX
Year: 2012
Journal: PLoS One
Title: Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.
Volume: 7
Issue: 11
Pages: e48782
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Publication
23630570 | J:200630
First Author: Wu W
Year: 2013
Journal: PLoS One
Title: Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain.
Volume: 8
Issue: 4
Pages: e59749
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Publication
23804095 | J:199637
First Author: Arsenault D
Year: 2013
Journal: J Neurosci
Title: PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and Aβ.
Volume: 33
Issue: 26
Pages: 10729-40
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Publication
39547338 | J:360793
 
First Author: Wang ZJ
Year: 2024
Journal: Neuroscience
Title: Semaglutide promotes the transition of microglia from M1 to M2 type to reduce brain inflammation in APP/PS1/tau mice.
Volume: 563
Pages: 222-234
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15748844 | J:99604
First Author: Billings LM
Year: 2005
Journal: Neuron
Title: Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.
Volume: 45
Issue: 5
Pages: 675-88
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Publication
28688899 | J:249714
 
First Author: Velazquez R
Year: 2017
Journal: Neurobiol Aging
Title: Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.
Volume: 58
Pages: 1-13
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37735133 | J:350206
First Author: Jin Y
Year: 2023
Journal: J Integr Neurosci
Title: Effect of Physical Exercise on Mitochondrial Dysfunction and Purkinje Cell Survival in the Cerebellum of 3xTg-AD Mice.
Volume: 22
Issue: 5
Pages: 117
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Publication
23523959 | J:197629
 
First Author: Torres-Lista V
Year: 2013
Journal: Behav Brain Res
Title: Impairment of nesting behaviour in 3xTg-AD mice.
Volume: 247
Pages: 153-7
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Publication
17456772 | J:121081
First Author: Caccamo A
Year: 2007
Journal: Am J Pathol
Title: Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.
Volume: 170
Issue: 5
Pages: 1669-75
•
•
•
•
•
Publication
23284867 | J:195625
First Author: Chakroborty S
Year: 2012
Journal: PLoS One
Title: Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease.
Volume: 7
Issue: 12
Pages: e52056
•
•
•
•
•
Publication
39142368 | J:353616
 
First Author: Ye Y
Year: 2024
Journal: Exp Neurol
Title: Alternate-day fasting improves cognitive and brain energy deficits by promoting ketone metabolism in the 3xTg mouse model of Alzheimer's disease.
Volume: 381
Pages: 114920
•
•
•
•
•
Publication
36758468 | J:351246
 
First Author: Li YY
Year: 2023
Journal: Neurobiol Aging
Title: Orexin-A aggravates cognitive deficits in 3xTg-AD mice by exacerbating synaptic plasticity impairment and affecting amyloid β metabolism.
Volume: 124
Pages: 71-84
•
•
•
•
•
Publication
32903435 | J:351249
 
First Author: Govindarajulu M
Year: 2020
Journal: Front Mol Neurosci
Title: Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress.
Volume: 13
Pages: 138
•
•
•
•
•
Publication
24726470 | J:214857
First Author: Han P
Year: 2014
Journal: Neurobiol Aging
Title: Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity.
Volume: 35
Issue: 9
Pages: 2064-71
•
•
•
•
•
Publication
27986924 | J:239169
First Author: Prieto GA
Year: 2017
Journal: J Neurosci
Title: Pharmacological Rescue of Long-Term Potentiation in Alzheimer Diseased Synapses.
Volume: 37
Issue: 5
Pages: 1197-1212
•
•
•
•
•
Publication
18698410 | J:140591
First Author: Rodríguez JJ
Year: 2008
Journal: PLoS One
Title: Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease.
Volume: 3
Issue: 8
Pages: e2935
•
•
•
•
•
Publication
38128868 | J:350218
 
First Author: He Z
Year: 2024
Journal: Eur J Pharmacol
Title: Comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside A on Alzheimer's disease.
Volume: 964
Pages: 176226
•
•
•
•
•
Publication
29859867 | J:268585
 
First Author: Silva AC
Year: 2018
Journal: Neurobiol Dis
Title: Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease.
Volume: 117
Pages: 72-81
•
•
•
•
•
Publication
28392767 | J:275595
 
First Author: Kazim SF
Year: 2017
Journal: Front Aging Neurosci
Title: Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer's Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade.
Volume: 9
Pages: 71
•
•
•
•
•
Publication
23152608 | J:192455
First Author: Lauritzen I
Year: 2012
Journal: J Neurosci
Title: The β-secretase-derived C-terminal fragment of βAPP, C99, but not Aβ, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus.
Volume: 32
Issue: 46
Pages: 16243-1655a
•
•
•
•
•
Publication
36788598 | J:351251
First Author: Brymer KJ
Year: 2023
Journal: Acta Neuropathol Commun
Title: Asymmetric dysregulation of glutamate dynamics across the synaptic cleft in a mouse model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 27
•
•
•
•
•
Publication
31186449 | J:278668
First Author: Xia Y
Year: 2019
Journal: Sci Rep
Title: Bifunctional Fluorescent/Raman Nanoprobe for the Early Detection of Amyloid.
Volume: 9
Issue: 1
Pages: 8497
•
•
•
•
•
Publication
33613267 | J:351250
 
First Author: Varinthra P
Year: 2021
Journal: Front Aging Neurosci
Title: The 4-(Phenylsulfanyl) butan-2-one Improves Impaired Fear Memory Retrieval and Reduces Excessive Inflammatory Response in Triple Transgenic Alzheimer's Disease Mice.
Volume: 13
Pages: 615079
•
•
•
•
•
Publication
37463909 | J:351252
First Author: Post LA
Year: 2023
Journal: Sci Rep
Title: Inceptor as a regulator of brain insulin sensitivity.
Volume: 13
Issue: 1
Pages: 11582
•
•
•
•
•
Publication
25008180 | J:230142
First Author: Vandal M
Year: 2014
Journal: Diabetes
Title: Insulin reverses the high-fat diet-induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease.
Volume: 63
Issue: 12
Pages: 4291-301
•
•
•
•
•




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