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Search results 301 to 337 out of 337 for Ptpra

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0.026s

Type

Details

Score

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:389486

First Author:	Mouse Genome Informatics and Ensembl Genome Database Project
Year:	2026
Journal:	Database Release
Title:	MGI Strain Genome Feature and Gene Model Load from Ensembl.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

28656243 | -

First Author:	Gu Z
Year:	2017
Journal:	Int J Oncol
Title:	Increased PTPRA expression leads to poor prognosis through c-Src activation and G1 phase progression in squamous cell lung cancer.
Volume:	51
Issue:	2
Pages:	489-497

•

Protein Domain

IPR065524 | R-PTPc-A-2

Type:

Domain

Description:

This entry represents the second PTP domain of Receptor-type tyrosine-protein phosphatase A.Receptor-type tyrosine-protein phosphatase A (PTPRA), also known as receptor-type tyrosine-protein phosphatase alpha (R-PTP-alpha), belongs to the family of classical tyrosine-specific protein tyrosine phosphatases (PTPs). PTPs () catalyse the dephosphorylation of phosphotyrosine peptides. PTPRA is a positive regulator of Src and Src family kinases via dephosphorylation of the Src-inhibitory tyrosine 527 [, ]. Thus, it affects transformation and tumourigenesis, inhibition of proliferation, cell cycle arrest, integrin signalling, neuronal differentiation and outgrowth, and ion channel activity [, , , , , , , , , , , , , , , , , , ]. It is also involved in interleukin-1 signalling in fibroblasts through its interaction with the focal adhesion targeting domain of focal adhesion kinase [, , ]. PTPRA comprises a small extracellular domain, a transmembrane segment, and an intracellular region containing two tandem PTP domains.

•

Protein Domain

IPR065525 | R-PTPc-A-1

Type:

Domain

Description:

This entry represents the first PTP domain of Receptor-type tyrosine-protein phosphatase A.Receptor-type tyrosine-protein phosphatase A (PTPRA), also known as receptor-type tyrosine-protein phosphatase alpha (R-PTP-alpha), belongs to the family of classical tyrosine-specific protein tyrosine phosphatases (PTPs). PTPs () catalyse the dephosphorylation of phosphotyrosine peptides. PTPRA is a positive regulator of Src and Src family kinases via dephosphorylation of the Src-inhibitory tyrosine 527 [, ]. Thus, it affects transformation and tumourigenesis, inhibition of proliferation, cell cycle arrest, integrin signalling, neuronal differentiation and outgrowth, and ion channel activity [, , , , , , , , , , , , , , , , , , ]. It is also involved in interleukin-1 signalling in fibroblasts through its interaction with the focal adhesion targeting domain of focal adhesion kinase [, , ]. PTPRA comprises a small extracellular domain, a transmembrane segment, and an intracellular region containing two tandem PTP domains.

•

Publication

28647856 | -

First Author:	Shih Y
Year:	2017
Journal:	J Mol Neurosci
Title:	Glial and Neuronal Protein Tyrosine Phosphatase Alpha (PTP??) Regulate Oligodendrocyte Differentiation and Myelination.
Volume:	62
Issue:	3-4
Pages:	329-343

•

Publication

27965091 | -

First Author:	Xiao J
Year:	2017
Journal:	Biochem Biophys Res Commun
Title:	??1,6 GlcNAc branches-modified protein tyrosine phosphatase alpha enhances its stability and promotes focal adhesion formation in MCF-7??cells.
Volume:	482
Issue:	4
Pages:	1455-1461

•

Publication

26611753 | J:237666

First Author:	Wang Q
Year:	2016
Journal:	Biochem J
Title:	A ternary complex comprising FAK, PTP? and IP3 receptor 1 functionally engages focal adhesions and the endoplasmic reticulum to mediate IL-1-induced Ca2+ signalling in fibroblasts.
Volume:	473
Issue:	4
Pages:	397-410

•

Publication

25940608 | -

First Author:	Lai X
Year:	2015
Journal:	FEBS J
Title:	Regulation of RPTP??-c-Src signalling pathway by miR-218.
Volume:	282
Issue:	14
Pages:	2722-34

•

Publication

25694432 | -

First Author:	Khanna RS
Year:	2015
Journal:	J Biol Chem
Title:	The interaction of protein-tyrosine phosphatase ?? (PTP??) and RACK1 protein enables insulin-like growth factor 1 (IGF-1)-stimulated Abl-dependent and -independent tyrosine phosphorylation of PTP??.
Volume:	290
Issue:	15
Pages:	9886-95

•

Publication

25625869 | -

First Author:	Fang XQ
Year:	2015
Journal:	Mol Med Rep
Title:	Focal adhesion kinase regulates the phosphorylation protein tyrosine phosphatase-?? at Tyr789 in breast cancer cells.
Volume:	11
Issue:	6
Pages:	4303-8

•

Publication

25393624 | -

First Author:	Xing J
Year:	2014
Journal:	PLoS One
Title:	Resequencing and association analysis of PTPRA, a possible susceptibility gene for schizophrenia and autism spectrum disorders.
Volume:	9
Issue:	11
Pages:	e112531

•

Publication

24821720 | -

First Author:	Wang Q
Year:	2014
Journal:	J Biol Chem
Title:	Interactions of the protein-tyrosine phosphatase-?? with the focal adhesion targeting domain of focal adhesion kinase are involved in interleukin-1 signaling in fibroblasts.
Volume:	289
Issue:	26
Pages:	18427-41

•

Publication

24248601 | -

First Author:	Cheng SY
Year:	2014
Journal:	Mol Cell Biol
Title:	Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase ?? by the Src-FAK kinase complex.
Volume:	34
Issue:	3
Pages:	348-61

•

Publication

24217252 | -

First Author:	Boivin B
Year:	2013
Journal:	J Biol Chem
Title:	Receptor protein-tyrosine phosphatase ?? regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein-mediated mammary epithelial cell motility.
Volume:	288
Issue:	52
Pages:	36926-35

•

Publication

23934023 | -

First Author:	Ma QH
Year:	2013
Journal:	Cell Adh Migr
Title:	Abnormal myelination in the spinal cord of PTP??-knockout mice.
Volume:	7
Issue:	4
Pages:	370-6

•

Publication

23532252 | -

First Author:	Wang J
Year:	2013
Journal:	Acta Biochim Biophys Sin (Shanghai)
Title:	PTP??-mediated Src activation by EGF in human breast cancer cells.
Volume:	45
Issue:	4
Pages:	320-9

•

Publication

23029023 | -

First Author:	Khoontawad J
Year:	2012
Journal:	PLoS One
Title:	Proteomic identification of plasma protein tyrosine phosphatase alpha and fibronectin associated with liver fluke, Opisthorchis viverrini, infection.
Volume:	7
Issue:	9
Pages:	e45460

•

Publication

21622556 | -

First Author:	Ye H
Year:	2011
Journal:	J Biol Chem
Title:	Receptor-like protein-tyrosine phosphatase ?? enhances cell surface expression of neural adhesion molecule NB-3.
Volume:	286
Issue:	29
Pages:	26071-80

•

Publication

22647903 | -

First Author:	Kapp K
Year:	2012
Journal:	Eur J Cell Biol
Title:	Proteolytic processing of the protein tyrosine phosphatase ?? extracellular domain is mediated by ADAM17/TACE.
Volume:	91
Issue:	9
Pages:	687-93

•

Publication

20472558 | -

First Author:	Wang Q
Year:	2010
Journal:	J Biol Chem
Title:	Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1-induced matrix metalloproteinase-3 expression.
Volume:	285
Issue:	29
Pages:	22308-17

•

Publication

28065597 | J:385268

First Author:	Yao Z
Year:	2017
Journal:	Mol Cell
Title:	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.
Volume:	65
Issue:	2
Pages:	347-360

•

Publication

12678847 | -

First Author:	Pallen CJ
Year:	2003
Journal:	Curr Top Med Chem
Title:	Protein tyrosine phosphatase alpha (PTPalpha): a Src family kinase activator and mediator of multiple biological effects.
Volume:	3
Issue:	7
Pages:	821-35

•

Publication

26573778 | -

First Author:	Alonso A
Year:	2016
Journal:	FEBS J
Title:	The extended human PTPome: a growing tyrosine phosphatase family.
Volume:	283
Issue:	8
Pages:	1404-29

•

Publication

17057753 | -

First Author:	Tonks NK
Year:	2006
Journal:	Nat Rev Mol Cell Biol
Title:	Protein tyrosine phosphatases: from genes, to function, to disease.
Volume:	7
Issue:	11
Pages:	833-46

•

Publication

27514797 | -

First Author:	Alonso A
Year:	2016
Journal:	Methods Mol Biol
Title:	The Extended Family of Protein Tyrosine Phosphatases.
Volume:	1447

Pages:	1-23

•

Protein

P18052

Organism:	Mus musculus/domesticus
Length:	829
Fragment?:	false

•

Protein

F8WGM1

Organism:	Mus musculus/domesticus
Length:	793
Fragment?:	false

•

Protein

Q91V35

Organism:	Mus musculus/domesticus
Length:	793
Fragment?:	false

•

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Search results 301 to 337 out of 337 for Ptpra

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