Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3716606 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-01-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:2622020 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:6386389 |
Age: |
embryonic day 12.5 |
Image: |
S1B/C |
|
Specimen Label: |
S1B/C |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3716606 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-01-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:2622021 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6386390 |
Age: |
embryonic day 13.5 |
Image: |
8G/H |
Note: |
Expression maintained in surrounding mesenchyme. |
Specimen Label: |
8G/H |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3716606 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-01-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:2622021 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6386390 |
Age: |
embryonic day 13.5 |
Image: |
8D/E |
|
Specimen Label: |
8D/E |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3716606 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2007-07-30 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287326 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:3716615 |
Age: |
embryonic day 18.5 |
Image: |
2g |
Note: |
Weak, but detectable, expression in intestinal villous epithelial cells, and in a subset of mesenchymal cells. |
Specimen Label: |
2g |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2991528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888214 |
|
Specimen Label: |
UC Davis_1888214 |
Detected: |
true |
Specimen Num: |
53 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2991528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888215 |
|
Specimen Label: |
UC Davis_1888215 |
Detected: |
true |
Specimen Num: |
54 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6194397 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-08-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689420 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:6194398 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
3A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888211 |
|
Specimen Label: |
UC Davis_1888211 |
Detected: |
true |
Specimen Num: |
50 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888212 |
|
Specimen Label: |
UC Davis_1888212 |
Detected: |
true |
Specimen Num: |
51 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1868228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888291 |
|
Specimen Label: |
UC Davis_1888291 |
Detected: |
true |
Specimen Num: |
118 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1868228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888292 |
|
Specimen Label: |
UC Davis_1888292 |
Detected: |
true |
Specimen Num: |
119 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888154 |
|
Specimen Label: |
UC Davis_1888154 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888155 |
|
Specimen Label: |
UC Davis_1888155 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888220 |
|
Specimen Label: |
UC Davis_1888220 |
Detected: |
true |
Specimen Num: |
58 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691840 |
Age: |
postnatal adult |
Image: |
UC Davis_1888221 |
|
Specimen Label: |
UC Davis_1888221 |
Detected: |
true |
Specimen Num: |
59 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6194397 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-08-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3787828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6194398 |
Age: |
postnatal day 23 |
|
Note: |
Expression is particularly prominent in the matrix of the early-anagen hair follicles of the new hair cycle. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6194397 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-08-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3787828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6194398 |
Age: |
postnatal day 28 |
|
Note: |
Expression is particularly prominent in the matrix of the mid-anagen hair follicles of the new hair cycle. |
Specimen Label: |
5B |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6194397 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-08-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3787628 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6194398 |
Age: |
postnatal day 21 |
|
Note: |
Expression is in the stem cell-containing bulge that lines the club hair. |
Specimen Label: |
5D |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li B |
Year: |
2004 |
Journal: |
Genomics |
Title: |
Cloning and developmental expression of mouse pygopus 2, a putative Wnt signaling component. |
Volume: |
84 |
Issue: |
2 |
Pages: |
398-405 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mieszczanek J |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models. |
Volume: |
10 |
Issue: |
1 |
Pages: |
724 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zimmerli D |
Year: |
2020 |
Journal: |
Elife |
Title: |
TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cantù C |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling. |
Volume: |
32 |
Issue: |
21-22 |
Pages: |
1443-1458 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cantù C |
Year: |
2014 |
Journal: |
Genes Dev |
Title: |
Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development. |
Volume: |
28 |
Issue: |
17 |
Pages: |
1879-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shull LC |
Year: |
2022 |
Journal: |
Development |
Title: |
PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation. |
Volume: |
149 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jonckheere N |
Year: |
2008 |
Journal: |
Dev Biol |
Title: |
Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. |
Volume: |
318 |
Issue: |
2 |
Pages: |
224-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin L |
Year: |
2021 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism. |
Volume: |
320 |
Issue: |
4 |
Pages: |
H1634-H1645 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
pygopus 2; targeted mutation 1.1, Xing Dai |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
259
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
90
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Willis TG |
Year: |
1998 |
Journal: |
Blood |
Title: |
Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21. |
Volume: |
91 |
Issue: |
6 |
Pages: |
1873-81 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
BCL9 is associated with B-cell acute lymphoblastic leukemia []. This entry includes BCL9 and BCL9L. They are tissue-specific transcriptional cofactors that cooperate with beta-catenin. In the nucleus, Bcl9 and Bcl9l simultaneously bind beta-catenin and the transcriptional activator Pygo2 to promote the transcription of a subset of Wnt target genes. They may also have a cytoplasmic role []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1494
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1425
 |
Fragment?: |
false |
|
•
•
•
•
•
|