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Search results 301 to 400 out of 436 for Rac2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein Coding Gene
MGI:1917834 | Pak4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2450166 | Arhgap32
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1933966 | Mcam
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2429763 | Dock3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2151070 | Ophn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q80TH2
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
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Protein
Q3U7R1
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
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Protein
Q6P1H6
Organism: Mus musculus/domesticus
Length: 964  
Fragment?: false
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Protein
Q68FF6
Organism: Mus musculus/domesticus
Length: 770  
Fragment?: false
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Protein
Q9Z207
Organism: Mus musculus/domesticus
Length: 1171  
Fragment?: false
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Protein
P62484
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
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Protein
Q99J31
Organism: Mus musculus/domesticus
Length: 802  
Fragment?: false
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Protein
O55111
Organism: Mus musculus/domesticus
Length: 1122  
Fragment?: false
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Protein
P28660
Organism: Mus musculus/domesticus
Length: 1128  
Fragment?: false
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Protein
Q80UU9
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
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Protein
Q8BTW9
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
Q8CBW3
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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Protein
Q8CIQ7
Organism: Mus musculus/domesticus
Length: 2027  
Fragment?: false
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Protein
Q99PT1
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: false
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Protein
Q91VR8
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
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Protein
Q8R2Y2
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
Q03145
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q5FWK3
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
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Protein
Q6ZQ82
Organism: Mus musculus/domesticus
Length: 814  
Fragment?: false
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Protein
Q6DFV3
Organism: Mus musculus/domesticus
Length: 1944  
Fragment?: false
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Protein
Q811P8
Organism: Mus musculus/domesticus
Length: 2089  
Fragment?: false
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Protein
P59281
Organism: Mus musculus/domesticus
Length: 1107  
Fragment?: false
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Protein
P97813
Organism: Mus musculus/domesticus
Length: 933  
Fragment?: false
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Protein
Q8BN21
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
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Protein
Q8BH43
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
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Protein Domain
IPR026799 | DOCK_2
Type: Family
Description: DOCK family members are evolutionarily conserved guanine nucleotide exchange factors (GEFs) for Rho-family GTPases []. DOCK proteins are required during several cellular processes, such as cell motility and phagocytosis. The N-terminal SH3 domain of the DOCK proteins functions as an inhibitor of GEF, which can be relieved upon its binding to the ELMO1-3 adaptor proteins, after their binding to active RhoG at the plasma membrane [, ]. DOCK family proteins are categorised into four subfamilies based on their sequence homology: DOCK-A subfamily (DOCK1/180, 2, 5), DOCK-B subfamily (DOCK3, 4), DOCK-C subfamily (DOCK6, 7, 8), DOCK-D subfamily (DOCK9, 10, 11) []. This entry represents DOCK2 (dedicator of cytokinesis 2). DOCK2 is involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. It activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. It may also participate in IL2 transcriptional activation via the activation of RAC2 [].
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Protein Coding Gene
MGI:107771 | Abr
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2145425 | Depdc1b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1349423 | Racgap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1926063 | Nckap1l
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98822 | Tfrc
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103306 | Tiam1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1917611 | Lman1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3040696 | Prex1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2159344 | Vangl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1338801 | Cyfip1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1352757 | Iqgap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96932 | Mcf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108117 | Emd
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:105068 | Rab7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q80Z96
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
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Protein
Q5SSL4
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: false
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Protein
Q7TMB8
Organism: Mus musculus/domesticus
Length: 1253  
Fragment?: false
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Protein
Q05144
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Protein
P51150
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Protein
Q9WVM1
Organism: Mus musculus/domesticus
Length: 628  
Fragment?: false
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Protein
Q9JKF1
Organism: Mus musculus/domesticus
Length: 1657  
Fragment?: false
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Protein
Q8K1X4
Organism: Mus musculus/domesticus
Length: 1134  
Fragment?: false
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Protein
O08579
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
Q8BH88
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
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Protein
Q9D0F3
Organism: Mus musculus/domesticus
Length: 517  
Fragment?: false
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Protein
Q69ZK0
Organism: Mus musculus/domesticus
Length: 1650  
Fragment?: false
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Protein
Q60610
Organism: Mus musculus/domesticus
Length: 1591  
Fragment?: false
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Protein
Q62351
Organism: Mus musculus/domesticus
Length: 763  
Fragment?: false
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Protein
Q8BLE2
Organism: Mus musculus/domesticus
Length: 1031  
Fragment?: false
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Protein Coding Gene
MGI:2138281 | Lbr
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1927230 | Trio
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2157953 | Rbm39
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1321389 | Vamp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929494 | Arhgap35
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913758 | Lamtor1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2429765 | Dock1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P63024
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
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Protein
Q8VH51
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
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Protein
Q61093
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Protein
O70145
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
P97369
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
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Protein
Q3U9G9
Organism: Mus musculus/domesticus
Length: 626  
Fragment?: false
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Protein
Q61462
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Protein
Q09014
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
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Protein
Q8BUR4
Organism: Mus musculus/domesticus
Length: 1865  
Fragment?: false
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Protein
Q9CQ22
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: false
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Protein
Q91YM2
Organism: Mus musculus/domesticus
Length: 1499  
Fragment?: false
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Protein
Q0KL02
Organism: Mus musculus/domesticus
Length: 3102  
Fragment?: false
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Protein Coding Gene
MGI:1919143 | Noxo1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2449980 | Noxa1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
38696257 | J:349934
 
First Author: Desai JV
Year: 2024
Journal: J Clin Invest
Title: BTK drives neutrophil activation for sterilizing antifungal immunity.
Volume: 134
Issue: 12
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Publication
17213284 | J:145328
First Author: Samayawardhena LA
Year: 2007
Journal: Blood
Title: Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells.
Volume: 109
Issue: 9
Pages: 3679-86
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Publication
16943182 | J:113266
First Author: Kunisaki Y
Year: 2006
Journal: J Cell Biol
Title: DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis.
Volume: 174
Issue: 5
Pages: 647-52
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Publication
19783987 | J:155132
First Author: Meacham CE
Year: 2009
Journal: Nat Genet
Title: In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression.
Volume: 41
Issue: 10
Pages: 1133-7
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Protein
A0A1B0GS53
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
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Protein
Q3TMS1
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Protein Coding Gene
MGI:2681162 | Nox3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1339984 | Pak2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:102718 | Vav2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1888518 | Vav3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109277 | Pik3r3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:102709 | Cav1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8CIN4
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
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Protein
Q64143
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
P49817
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
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Protein
Q9R0C8
Organism: Mus musculus/domesticus
Length: 847  
Fragment?: false
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Protein
Q60992
Organism: Mus musculus/domesticus
Length: 868  
Fragment?: false
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Publication
16621998 | J:131659
First Author: Condliffe AM
Year: 2006
Journal: J Immunol
Title: RhoG regulates the neutrophil NADPH oxidase.
Volume: 176
Issue: 9
Pages: 5314-20
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Publication
24333420 | J:211863
First Author: Ko SH
Year: 2014
Journal: Biochem Biophys Res Commun
Title: 8-Oxo-2'-deoxyguanosine ameliorates features of metabolic syndrome in obese mice.
Volume: 443
Issue: 2
Pages: 610-6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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