| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Pseudogene |
| Type: |
pseudogene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hosono K |
| Year: |
2010 |
| Journal: |
Genomics |
| Title: |
YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10. |
| Volume: |
96 |
| Issue: |
2 |
| Pages: |
102-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Steggerda SM |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
The mammalian Mog1 protein is a guanine nucleotide release factor for Ran. |
| Volume: |
275 |
| Issue: |
30 |
| Pages: |
23175-80 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
Ran guanine nucleotide release factor |
| Type: |
chain |
| End: |
185 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu L |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5. |
| Volume: |
283 |
| Issue: |
11 |
| Pages: |
6968-78 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents a group of RanGTP-binding proteins that contain a conserved RanGTP-binding motif, also called a Ran-binding domain (RBD). They have been implicated in nucleocytoplasmic transport. NUP358 (RanBP2) is localised to the cytoplasmic filaments protruding from the nuclear pore complex (NPC) into the cytoplasm, while RanBP3/Hba1 are localised to the nucleoplasm and Nup2 is localised to the NPC. In general, RanBP1 and other members of this protein family increase, via their conserved RBDs, the rate of RanGAP1-mediated GTP hydrolysis on Ran []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cho KI |
| Year: |
2010 |
| Journal: |
Dis Model Mech |
| Title: |
Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress. |
| Volume: |
3 |
| Issue: |
9-10 |
| Pages: |
595-604 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nguyen L |
| Year: |
2020 |
| Journal: |
Neuron |
| Title: |
Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model. |
| Volume: |
105 |
| Issue: |
4 |
| Pages: |
645-662.e11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bernier-Villamor V |
| Year: |
2002 |
| Journal: |
Cell |
| Title: |
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. |
| Volume: |
108 |
| Issue: |
3 |
| Pages: |
345-56 |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
144
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
589
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kunert S |
| Year: |
2009 |
| Journal: |
Blood |
| Title: |
The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation. |
| Volume: |
114 |
| Issue: |
27 |
| Pages: |
5532-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cho KI |
| Year: |
2015 |
| Journal: |
FEBS Lett |
| Title: |
Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2). |
| Volume: |
589 |
| Issue: |
24 Pt B |
| Pages: |
3959-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cho KI |
| Year: |
2009 |
| Journal: |
Cell Death Differ |
| Title: |
Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
287-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cho KI |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis. |
| Volume: |
289 |
| Issue: |
8 |
| Pages: |
4600-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Palavicini JP |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
e66908 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Puverel S |
| Year: |
2016 |
| Journal: |
Oncotarget |
| Title: |
RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells. |
| Volume: |
7 |
| Issue: |
51 |
| Pages: |
85109-85123 |
|
•
•
•
•
•
|