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Search results 301 to 400 out of 1661 for Rb1

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Type Details Score
Publication
First Author: Cheng L
Year: 2010
Journal: Oncogene
Title: Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency.
Volume: 29
Issue: 42
Pages: 5700-11
Publication      
First Author: Li N
Year: 2018
Journal: Oncogene
Title: Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades.
Publication
First Author: Shakhova O
Year: 2006
Journal: Cancer Res
Title: Lack of Rb and p53 delays cerebellar development and predisposes to large cell anaplastic medulloblastoma through amplification of N-Myc and Ptch2.
Volume: 66
Issue: 10
Pages: 5190-200
Publication
First Author: Norris AM
Year: 2013
Journal: Oncogene
Title: AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.
Volume: 32
Issue: 33
Pages: 3867-76
Publication
First Author: Denny SK
Year: 2016
Journal: Cell
Title: Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.
Volume: 166
Issue: 2
Pages: 328-342
Publication
First Author: Borromeo MD
Year: 2016
Journal: Cell Rep
Title: ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs.
Volume: 16
Issue: 5
Pages: 1259-1272
Publication
First Author: Lázaro S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes.
Volume: 116
Issue: 44
Pages: 22300-22306
Publication
First Author: Chen KS
Year: 2021
Journal: Carcinogenesis
Title: NFIA and NFIB function as tumour suppressors in high-grade glioma in mice.
Volume: 42
Issue: 3
Pages: 357-368
Publication  
First Author: Meder L
Year: 2024
Journal: JCI Insight
Title: Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis.
Volume: 9
Issue: 10
Publication
First Author: Zhang Y
Year: 2014
Journal: Dev Biol
Title: Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.
Volume: 396
Issue: 1
Pages: 19-30
Publication
First Author: Segovia C
Year: 2019
Journal: Nat Med
Title: Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression.
Volume: 25
Issue: 7
Pages: 1073-1081
Publication
First Author: Jia D
Year: 2018
Journal: Cancer Discov
Title: Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition.
Volume: 8
Issue: 11
Pages: 1422-1437
Publication  
First Author: Lázaro S
Year: 2022
Journal: Cancers (Basel)
Title: Pten and p53 Loss in the Mouse Lung Causes Adenocarcinoma and Sarcomatoid Carcinoma.
Volume: 14
Issue: 15
Publication
First Author: Gao G
Year: 2023
Journal: Nat Commun
Title: The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer.
Volume: 14
Issue: 1
Pages: 363
Publication
First Author: Abedalthagafi MS
Year: 2016
Journal: J Pathol
Title: Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours.
Volume: 238
Issue: 4
Pages: 584-97
Publication
First Author: Walters BJ
Year: 2014
Journal: J Neurosci
Title: Auditory hair cell-specific deletion of p27Kip1 in postnatal mice promotes cell-autonomous generation of new hair cells and normal hearing.
Volume: 34
Issue: 47
Pages: 15751-63
Publication
First Author: McCool KW
Year: 2020
Journal: Cancer Res
Title: Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts.
Volume: 80
Issue: 4
Pages: 877-889
Publication
First Author: Reed C
Year: 2014
Journal: Am J Pathol
Title: RB tumor suppressive function in response to xenobiotic hepatocarcinogens.
Volume: 184
Issue: 6
Pages: 1853-9
Publication
First Author: Ghazaryan S
Year: 2014
Journal: Mol Cell Biol
Title: Inactivation of Rb and E2f8 synergizes to trigger stressed DNA replication during erythroid terminal differentiation.
Volume: 34
Issue: 15
Pages: 2833-47
Publication
First Author: Li W
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition.
Volume: 106
Issue: 2
Pages: 486-91
Publication
First Author: Shamma A
Year: 2009
Journal: Cancer Cell
Title: Rb Regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-ras isoprenylation.
Volume: 15
Issue: 4
Pages: 255-69
Publication
First Author: Chong JL
Year: 2009
Journal: Mol Cell Biol
Title: E2f3a and E2f3b contribute to the control of cell proliferation and mouse development.
Volume: 29
Issue: 2
Pages: 414-24
Publication
First Author: Bultman SJ
Year: 2008
Journal: Oncogene
Title: Characterization of mammary tumors from Brg1 heterozygous mice.
Volume: 27
Issue: 4
Pages: 460-8
Publication
First Author: Walters BJ
Year: 2017
Journal: Cell Rep
Title: In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.
Volume: 19
Issue: 2
Pages: 307-320
Publication
First Author: Parisi T
Year: 2007
Journal: Mol Cell Biol
Title: Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues.
Volume: 27
Issue: 6
Pages: 2283-93
Publication
First Author: Donovan SL
Year: 2004
Journal: Vision Res
Title: Developmental defects in Rb-deficient retinae.
Volume: 44
Issue: 28
Pages: 3323-33
Publication
First Author: Sung YH
Year: 2010
Journal: Cancer Res
Title: Pierce1, a novel p53 target gene contributing to the ultraviolet-induced DNA damage response.
Volume: 70
Issue: 24
Pages: 10454-63
Publication
First Author: Baker DJ
Year: 2009
Journal: Cancer Cell
Title: Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity.
Volume: 16
Issue: 6
Pages: 475-86
Publication
First Author: Vooijs M
Year: 2002
Journal: Cancer Res
Title: Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.
Volume: 62
Issue: 6
Pages: 1862-7
Publication
First Author: Svoboda DS
Year: 2013
Journal: Dev Biol
Title: Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis.
Volume: 384
Issue: 1
Pages: 101-13
Publication
First Author: Fang M
Year: 2014
Journal: Oncogene
Title: Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival.
Volume: 33
Issue: 10
Pages: 1336-9
Publication
First Author: Conkrite K
Year: 2012
Journal: J Clin Invest
Title: Cooperation between Rb and Arf in suppressing mouse retinoblastoma.
Volume: 122
Issue: 5
Pages: 1726-33
Publication
First Author: Donangelo I
Year: 2005
Journal: J Endocrinol Invest
Title: Pathophysiology of pituitary adenomas.
Volume: 28
Issue: 11 Suppl International
Pages: 100-5
Publication
First Author: Cai EP
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate.
Volume: 110
Issue: 36
Pages: 14723-8
Publication
First Author: Guo Z
Year: 2001
Journal: Cancer Res
Title: Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis.
Volume: 61
Issue: 23
Pages: 8395-400
Publication
First Author: Liu Y
Year: 2000
Journal: Oncogene
Title: E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses.
Volume: 19
Issue: 52
Pages: 6065-73
Publication
First Author: Wang Y
Year: 2007
Journal: Dev Biol
Title: The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression.
Volume: 311
Issue: 2
Pages: 478-86
Publication
First Author: Keramaris E
Year: 2008
Journal: J Biol Chem
Title: Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice.
Volume: 283
Issue: 1
Pages: 405-15
Publication  
First Author: Yang HS
Year: 2007
Journal: BMC Dev Biol
Title: pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.
Volume: 7
Pages: 6
Publication  
First Author: Schmitt CA
Year: 2000
Journal: Cold Spring Harb Symp Quant Biol
Title: DNA damage responses and chemosensitivity in the E mu-myc mouse lymphoma model.
Volume: 65
Pages: 499-510
Publication
First Author: Schmitt CA
Year: 1999
Journal: Genes Dev
Title: INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.
Volume: 13
Issue: 20
Pages: 2670-7
Publication
First Author: Benavente CA
Year: 2013
Journal: Oncotarget
Title: Cross-species genomic and epigenomic landscape of retinoblastoma.
Volume: 4
Issue: 6
Pages: 844-59
Publication
First Author: Bajenaru ML
Year: 2001
Journal: Glia
Title: Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes.
Volume: 33
Issue: 4
Pages: 314-23
Publication
First Author: Seoane M
Year: 2011
Journal: PLoS One
Title: The mitochondrial genome is a "genetic sanctuary" during the oncogenic process.
Volume: 6
Issue: 8
Pages: e23327
Publication
First Author: Mulligan G
Year: 1998
Journal: Trends Genet
Title: The retinoblastoma gene family: cousins with overlapping interests.
Volume: 14
Issue: 6
Pages: 223-9
Publication
First Author: Remy E
Year: 2015
Journal: Cancer Res
Title: A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis.
Volume: 75
Issue: 19
Pages: 4042-52
Publication
First Author: Jiang Z
Year: 2000
Journal: Dev Biol
Title: E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis.
Volume: 227
Issue: 1
Pages: 8-41
Publication
First Author: Reimann M
Year: 2007
Journal: Blood
Title: The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Volume: 110
Issue: 8
Pages: 2996-3004
Publication
First Author: Cecchini MJ
Year: 2014
Journal: Mol Cell Biol
Title: A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice.
Volume: 34
Issue: 11
Pages: 2029-45
Publication
First Author: Maandag EC
Year: 1994
Journal: EMBO J
Title: Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice.
Volume: 13
Issue: 18
Pages: 4260-8
Publication
First Author: Zhang H
Year: 2020
Journal: Cancer Cell
Title: CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Volume: 37
Issue: 1
Pages: 37-54.e9
Publication
First Author: Ji Y
Year: 2023
Journal: Nat Commun
Title: The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer.
Volume: 14
Issue: 1
Pages: 7794
Publication
First Author: Pakula H
Year: 2024
Journal: Nat Commun
Title: Distinct mesenchymal cell states mediate prostate cancer progression.
Volume: 15
Issue: 1
Pages: 363
Publication
First Author: Miller KA
Year: 2024
Journal: Oncogene
Title: PTEN-regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression.
Volume: 43
Issue: 1
Pages: 22-34
Publication
First Author: Maund SL
Year: 2011
Journal: Cancer Res
Title: Interleukin-1α mediates the antiproliferative effects of 1,25-dihydroxyvitamin D3 in prostate progenitor/stem cells.
Volume: 71
Issue: 15
Pages: 5276-86
Publication
First Author: Qin Q
Year: 2022
Journal: Cancer Res
Title: NELL1 Regulates the Matrisome to Promote Osteosarcoma Progression.
Volume: 82
Issue: 15
Pages: 2734-2747
Publication
First Author: Hwang CI
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Wild-type p53 controls cell motility and invasion by dual regulation of MET expression.
Volume: 108
Issue: 34
Pages: 14240-5
Publication
First Author: MacLeod G
Year: 2024
Journal: Cancer Res
Title: Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities.
Volume: 84
Issue: 23
Pages: 3967-3983
Publication      
First Author: Jurmeister S
Year: 2018
Journal: EMBO Mol Med
Title: Identification of potential therapeutic targets in prostate cancer through a cross-species approach.
Publication
First Author: Wenzel PL
Year: 2007
Journal: Genes Dev
Title: Rb is critical in a mammalian tissue stem cell population.
Volume: 21
Issue: 1
Pages: 85-97
Publication
First Author: Ajioka I
Year: 2007
Journal: Cell
Title: Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice.
Volume: 131
Issue: 2
Pages: 378-90
Publication
First Author: Ferguson KL
Year: 2002
Journal: EMBO J
Title: Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development.
Volume: 21
Issue: 13
Pages: 3337-46
Publication
First Author: Hoefflin R
Year: 2020
Journal: Nat Commun
Title: HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Volume: 11
Issue: 1
Pages: 4111
Publication
First Author: Song H
Year: 2017
Journal: J Biol Chem
Title: Selective Ablation of Tumor Suppressors in Parafollicular C Cells Elicits Medullary Thyroid Carcinoma.
Volume: 292
Issue: 9
Pages: 3888-3899
Publication  
First Author: Kumar R
Year: 2022
Journal: J Clin Invest
Title: A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60.
Volume: 132
Issue: 13
Publication
First Author: Daikoku T
Year: 2006
Journal: Cancer Res
Title: Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.
Volume: 66
Issue: 5
Pages: 2527-31
Publication
First Author: Farago AF
Year: 2012
Journal: Cell
Title: SnapShot: Lung cancer models.
Volume: 149
Issue: 1
Pages: 246-246.e1
Publication
First Author: Langdon CG
Year: 2021
Journal: Nat Commun
Title: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity.
Volume: 12
Issue: 1
Pages: 5520
Publication
First Author: Dackor J
Year: 2007
Journal: Placenta
Title: Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryos.
Volume: 28
Issue: 11-12
Pages: 1211-8
Publication
First Author: Zocchi L
Year: 2020
Journal: Oncogenesis
Title: Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression.
Volume: 9
Issue: 2
Pages: 25
Publication
First Author: Mantela J
Year: 2005
Journal: Development
Title: The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.
Volume: 132
Issue: 10
Pages: 2377-88
Publication
First Author: Andrusiak MG
Year: 2012
Journal: J Neurosci
Title: The retinoblastoma protein is essential for survival of postmitotic neurons.
Volume: 32
Issue: 42
Pages: 14809-14
Publication
First Author: Lim JS
Year: 2017
Journal: Nature
Title: Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Volume: 545
Issue: 7654
Pages: 360-364
Publication
First Author: Knostman KA
Year: 2007
Journal: Vet Pathol
Title: Genetic alterations in thyroid cancer: the role of mouse models.
Volume: 44
Issue: 1
Pages: 1-14
Publication
First Author: Park KK
Year: 2008
Journal: Science
Title: Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway.
Volume: 322
Issue: 5903
Pages: 963-6
Publication
First Author: Johnson DA
Year: 2007
Journal: Cancer Res
Title: Neuronal differentiation and synaptogenesis in retinoblastoma.
Volume: 67
Issue: 6
Pages: 2701-11
Publication  
First Author: Yu R
Year: 2016
Journal: Mol Cell Endocrinol
Title: Animal models of spontaneous pancreatic neuroendocrine tumors.
Volume: 421
Pages: 60-7
Publication
First Author: Song H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis.
Volume: 109
Issue: 43
Pages: 17531-6
Publication
First Author: Andrusiak MG
Year: 2011
Journal: Mol Cell Biol
Title: Rb/E2F regulates expression of neogenin during neuronal migration.
Volume: 31
Issue: 2
Pages: 238-47
Publication
First Author: McClellan KA
Year: 2007
Journal: Mol Cell Biol
Title: Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.
Volume: 27
Issue: 13
Pages: 4825-43
Publication
First Author: Pearson JD
Year: 2021
Journal: Cancer Cell
Title: Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.
Volume: 39
Issue: 8
Pages: 1115-1134.e12
Publication
First Author: McClellan KA
Year: 2009
Journal: Mol Cell Biol
Title: The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells.
Volume: 29
Issue: 17
Pages: 4701-13
Publication
First Author: Gardner EE
Year: 2024
Journal: Science
Title: Lineage-specific intolerance to oncogenic drivers restricts histological transformation.
Volume: 383
Issue: 6683
Pages: eadj1415
Publication
First Author: Bakkar N
Year: 2008
Journal: J Cell Biol
Title: IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis.
Volume: 180
Issue: 4
Pages: 787-802
Publication
First Author: Isaac CE
Year: 2006
Journal: Mol Cell Biol
Title: The retinoblastoma protein regulates pericentric heterochromatin.
Volume: 26
Issue: 9
Pages: 3659-71
Publication
First Author: Ghanem N
Year: 2012
Journal: J Neurosci
Title: The Rb/E2F pathway modulates neurogenesis through direct regulation of the Dlx1/Dlx2 bigene cluster.
Volume: 32
Issue: 24
Pages: 8219-30
Publication  
First Author: Ku SY
Year: 2024
Journal: J Clin Invest
Title: Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer.
Volume: 134
Issue: 17
Publication
First Author: Sturmlechner I
Year: 2021
Journal: Science
Title: p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
Volume: 374
Issue: 6567
Pages: eabb3420
Publication  
First Author: Jaafar C
Year: 2016
Journal: Front Mol Neurosci
Title: Role of Rb during Neurogenesis and Axonal Guidance in the Developing Olfactory System.
Volume: 9
Pages: 81
Allele
Name: neuroligin 3; targeted mutation 4, Thomas C Sudhof
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Publication
First Author: Tonks ID
Year: 2005
Journal: Pigment Cell Res
Title: Melanocytes in conditional Rb-/- mice are normal in vivo but exhibit proliferation and pigmentation defects in vitro.
Volume: 18
Issue: 4
Pages: 252-64
Publication
First Author: Francis SM
Year: 2011
Journal: PLoS One
Title: A context-specific role for retinoblastoma protein-dependent negative growth control in suppressing mammary tumorigenesis.
Volume: 6
Issue: 2
Pages: e16434
Publication
First Author: Francis SM
Year: 2009
Journal: Mol Cell Biol
Title: A functional connection between pRB and transforming growth factor beta in growth inhibition and mammary gland development.
Volume: 29
Issue: 16
Pages: 4455-66
Publication
First Author: Nicolay BN
Year: 2015
Journal: Genes Dev
Title: Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation.
Volume: 29
Issue: 17
Pages: 1875-89
Publication
First Author: Singh HP
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Developmental stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors.
Volume: 115
Issue: 40
Pages: E9391-E9400
Publication
First Author: Steenpass L
Year: 2013
Journal: PLoS One
Title: Human PPP1R26P1 functions as cis-repressive element in mouse Rb1.
Volume: 8
Issue: 9
Pages: e74159
Publication
First Author: Goodrich DW
Year: 2003
Journal: J Cell Physiol
Title: How the other half lives, the amino-terminal domain of the retinoblastoma tumor suppressor protein.
Volume: 197
Issue: 2
Pages: 169-80
Publication
First Author: Feng S
Year: 2011
Journal: Nucleic Acids Res
Title: MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells.
Volume: 39
Issue: 15
Pages: 6669-78
Publication
First Author: Wikenheiser-Brokamp KA
Year: 2006
Journal: Cell Mol Life Sci
Title: Retinoblastoma family proteins: insights gained through genetic manipulation of mice.
Volume: 63
Issue: 7-8
Pages: 767-80
Publication
First Author: Mollaoglu G
Year: 2017
Journal: Cancer Cell
Title: MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.
Volume: 31
Issue: 2
Pages: 270-285