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Search results 301 to 400 out of 768 for Rorc

0.033s
Type Details Score
Publication      
First Author: Zhang J
Year: 2021
Journal: J Immunol
Title: USP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity.
Publication
First Author: Abarrategui I
Year: 2007
Journal: EMBO J
Title: Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination.
Volume: 26
Issue: 20
Pages: 4380-90
Publication
First Author: Hawwari A
Year: 2005
Journal: Nat Immunol
Title: Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters.
Volume: 6
Issue: 5
Pages: 481-9
Publication
First Author: Hawwari A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Role for rearranged variable gene segments in directing secondary T cell receptor alpha recombination.
Volume: 104
Issue: 3
Pages: 903-7
Publication
First Author: Mongrain V
Year: 2008
Journal: Genes Cells
Title: Clock-dependent and independent transcriptional control of the two isoforms from the mouse Rorgamma gene.
Volume: 13
Issue: 12
Pages: 1197-210
Publication
First Author: Wang R
Year: 2011
Journal: J Immunol
Title: T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Volume: 187
Issue: 11
Pages: 5964-73
Publication
First Author: He Z
Year: 2019
Journal: J Immunol
Title: SRC3 Is a Cofactor for RORγt in Th17 Differentiation but Not Thymocyte Development.
Volume: 202
Issue: 3
Pages: 760-769
Publication  
First Author: Luo S
Year: 2021
Journal: JCI Insight
Title: CD138 expression is a molecular signature but not a developmental requirement for RORγt+ NKT17 cells.
Volume: 6
Issue: 18
Publication
First Author: Yu Y
Year: 2011
Journal: Blood
Title: Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice.
Volume: 118
Issue: 18
Pages: 5011-20
Publication
First Author: Shimizu M
Year: 2021
Journal: Sci Rep
Title: T-bet represses collagen-induced arthritis by suppressing Th17 lineage commitment through inhibition of RORγt expression and function.
Volume: 11
Issue: 1
Pages: 17357
Publication
First Author: Bezbradica JS
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny.
Volume: 102
Issue: 14
Pages: 5114-9
Publication
First Author: Shields JD
Year: 2010
Journal: Science
Title: Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21.
Volume: 328
Issue: 5979
Pages: 749-52
Publication
First Author: Lebson L
Year: 2010
Journal: J Immunol
Title: Cutting edge: The transcription factor Kruppel-like factor 4 regulates the differentiation of Th17 cells independently of RORγt.
Volume: 185
Issue: 12
Pages: 7161-4
Publication
First Author: He Z
Year: 2017
Journal: J Immunol
Title: Regulation of Th17 Differentiation by IKKα-Dependent and -Independent Phosphorylation of RORγt.
Volume: 199
Issue: 3
Pages: 955-964
Publication
First Author: Buonocore S
Year: 2010
Journal: Nature
Title: Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.
Volume: 464
Issue: 7293
Pages: 1371-5
Publication
First Author: Gribonika I
Year: 2022
Journal: Sci Immunol
Title: Peyer's patch T(H)17 cells are dispensable for gut IgA responses to oral immunization.
Volume: 7
Issue: 73
Pages: eabc5500
Publication    
First Author: Philips RL
Year: 2019
Journal: Elife
Title: HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment.
Volume: 8
Publication
First Author: Wichner K
Year: 2016
Journal: FASEB J
Title: Dysregulated development of IL-17- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.
Volume: 30
Issue: 2
Pages: 761-74
Publication
First Author: Strauss L
Year: 2015
Journal: Cancer Cell
Title: RORC1 Regulates Tumor-Promoting "Emergency" Granulo-Monocytopoiesis.
Volume: 28
Issue: 2
Pages: 253-69
Publication
First Author: Lee S
Year: 2020
Journal: iScience
Title: RORγt-driven T(H)17 Cell Differentiation Requires Epigenetic Control by the Swi/Snf Chromatin Remodeling Complex.
Volume: 23
Issue: 5
Pages: 101106
Publication
First Author: Lainé A
Year: 2015
Journal: J Immunol
Title: Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORγt-Th17 Program.
Volume: 195
Issue: 4
Pages: 1791-803
Publication    
First Author: Erice PA
Year: 2024
Journal: Elife
Title: Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt.
Volume: 13
Publication
First Author: Obermajer N
Year: 2014
Journal: J Immunol
Title: Conversion of Th17 into IL-17A(neg) regulatory T cells: a novel mechanism in prolonged allograft survival promoted by mesenchymal stem cell-supported minimized immunosuppressive therapy.
Volume: 193
Issue: 10
Pages: 4988-99
Publication
First Author: Yoshida H
Year: 2019
Journal: Cell
Title: The cis-Regulatory Atlas of the Mouse Immune System.
Volume: 176
Issue: 4
Pages: 897-912.e20
Publication
First Author: Medina-Rodriguez EM
Year: 2020
Journal: Am J Psychiatry
Title: Identification of a Signaling Mechanism by Which the Microbiome Regulates Th17 Cell-Mediated Depressive-Like Behaviors in Mice.
Volume: 177
Issue: 10
Pages: 974-990
Publication
First Author: Magri G
Year: 2014
Journal: Nat Immunol
Title: Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.
Volume: 15
Issue: 4
Pages: 354-364
Publication
First Author: McGuire DJ
Year: 2014
Journal: Eur J Immunol
Title: CD5 enhances Th17-cell differentiation by regulating IFN-γ response and RORγt localization.
Volume: 44
Issue: 4
Pages: 1137-42
Publication
First Author: Bhattacharjee A
Year: 2021
Journal: Immunity
Title: Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy.
Volume: 54
Issue: 8
Pages: 1745-1757.e7
Publication
First Author: Ano S
Year: 2013
Journal: J Immunol
Title: Transcription factors GATA-3 and RORγt are important for determining the phenotype of allergic airway inflammation in a murine model of asthma.
Volume: 190
Issue: 3
Pages: 1056-65
Publication
First Author: Potchen NB
Year: 2023
Journal: iScience
Title: Oral tolerance to systemic vaccination remains intact without RORγt expression in regulatory T cells.
Volume: 26
Issue: 12
Pages: 108504
Publication
First Author: Kluger MA
Year: 2017
Journal: Clin Exp Immunol
Title: RORγt expression in Tregs promotes systemic lupus erythematosus via IL-17 secretion, alteration of Treg phenotype and suppression of Th2 responses.
Volume: 188
Issue: 1
Pages: 63-78
Publication
First Author: Skepner J
Year: 2015
Journal: Immunology
Title: In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists.
Volume: 145
Issue: 3
Pages: 347-56
Publication
First Author: Solt LA
Year: 2015
Journal: Endocrinology
Title: ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes.
Volume: 156
Issue: 3
Pages: 869-81
Publication
First Author: Talia DM
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Inhibition of the Nuclear Receptor RORγ and Interleukin-17A Suppresses Neovascular Retinopathy: Involvement of Immunocompetent Microglia.
Volume: 36
Issue: 6
Pages: 1186-96
Publication
First Author: Takeda Y
Year: 2013
Journal: Nucleic Acids Res
Title: Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation.
Volume: 41
Issue: 14
Pages: 6992-7008
Publication
First Author: Poliandri AH
Year: 2011
Journal: J Biol Rhythms
Title: Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140).
Volume: 26
Issue: 3
Pages: 187-99
Publication
First Author: Kathania M
Year: 2020
Journal: J Immunol
Title: Gut Microbiota Contributes to Spontaneous Colitis in E3 Ligase Itch-Deficient Mice.
Volume: 204
Issue: 8
Pages: 2277-2284
Publication
First Author: Yuan J
Year: 2010
Journal: J Immunol
Title: c-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xL.
Volume: 184
Issue: 6
Pages: 2793-804
Publication
First Author: Ribot JC
Year: 2009
Journal: Nat Immunol
Title: CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets.
Volume: 10
Issue: 4
Pages: 427-36
Publication
First Author: Teng F
Year: 2016
Journal: Immunity
Title: Gut Microbiota Drive Autoimmune Arthritis by Promoting Differentiation and Migration of Peyer's Patch T Follicular Helper Cells.
Volume: 44
Issue: 4
Pages: 875-88
Publication  
First Author: Mu Q
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Regulation of neonatal IgA production by the maternal microbiota.
Volume: 118
Issue: 9
Publication
First Author: Chan AJ
Year: 2014
Journal: Am J Pathol
Title: Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation.
Volume: 184
Issue: 5
Pages: 1411-8
Publication
First Author: Ruan Q
Year: 2011
Journal: J Exp Med
Title: The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis.
Volume: 208
Issue: 11
Pages: 2321-33
Publication
First Author: Yoh K
Year: 2012
Journal: Eur J Immunol
Title: Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice.
Volume: 42
Issue: 8
Pages: 1999-2009
Publication
First Author: Alexander M
Year: 2022
Journal: Cell Host Microbe
Title: Human gut bacterial metabolism drives Th17 activation and colitis.
Volume: 30
Issue: 1
Pages: 17-30.e9
Publication
First Author: Sun M
Year: 2019
Journal: J Immunol
Title: RORγt Represses IL-10 Production in Th17 Cells To Maintain Their Pathogenicity in Inducing Intestinal Inflammation.
Volume: 202
Issue: 1
Pages: 79-92
Publication
First Author: Amir M
Year: 2018
Journal: Cell Rep
Title: REV-ERBα Regulates TH17 Cell Development and Autoimmunity.
Volume: 25
Issue: 13
Pages: 3733-3749.e8
Publication
First Author: Wang R
Year: 2021
Journal: Nat Commun
Title: Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders.
Volume: 12
Issue: 1
Pages: 76
Publication
First Author: Kathania M
Year: 2022
Journal: Cell Rep
Title: Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation.
Volume: 40
Issue: 11
Pages: 111345
Publication
First Author: Bhatt B
Year: 2018
Journal: J Immunol
Title: Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation.
Volume: 200
Issue: 8
Pages: 2905-2914
Publication
First Author: Torres-Huerta A
Year: 2024
Journal: PLoS One
Title: Retinoid orphan receptor gamma t (rorγt) promotes inflammatory eosinophilia but is dispensable for innate immune-mediated colitis.
Volume: 19
Issue: 3
Pages: e0300892
Publication      
First Author: Zhang Y
Year: 2017
Journal: Genes Dev
Title: The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ.
Publication
First Author: Lutz SE
Year: 2017
Journal: Cell Rep
Title: Caveolin1 Is Required for Th1 Cell Infiltration, but Not Tight Junction Remodeling, at the Blood-Brain Barrier in Autoimmune Neuroinflammation.
Volume: 21
Issue: 8
Pages: 2104-2117
Publication
First Author: Block KE
Year: 2013
Journal: J Immunol
Title: The cellular source and target of IL-21 in K/BxN autoimmune arthritis.
Volume: 191
Issue: 6
Pages: 2948-55
Publication
First Author: Philips RL
Year: 2019
Journal: J Immunol
Title: Cutting Edge: HDAC3 Protects Double-Positive Thymocytes from P2X7 Receptor-Induced Cell Death.
Volume: 202
Issue: 4
Pages: 1033-1038
Publication
First Author: Chang C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease.
Volume: 116
Issue: 37
Pages: 18528-18536
Publication
First Author: Iizuka M
Year: 2015
Journal: J Immunol
Title: A crucial role of RORγt in the development of spontaneous Sialadenitis-like Sjögren's syndrome.
Volume: 194
Issue: 1
Pages: 56-67
Publication
First Author: Bär E
Year: 2014
Journal: Immunity
Title: IL-17 regulates systemic fungal immunity by controlling the functional competence of NK cells.
Volume: 40
Issue: 1
Pages: 117-27
Publication  
First Author: Downs-Canner S
Year: 2017
Journal: Nat Commun
Title: Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells.
Volume: 8
Pages: 14649
Publication
First Author: Haas JD
Year: 2011
Journal: PLoS One
Title: Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells.
Volume: 6
Issue: 5
Pages: e20171
Publication
First Author: Polese B
Year: 2021
Journal: Cell Rep
Title: Prostaglandin E2 amplifies IL-17 production by γδ T cells during barrier inflammation.
Volume: 36
Issue: 4
Pages: 109456
Publication
First Author: Yamashita T
Year: 2011
Journal: Cardiovasc Res
Title: IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis.
Volume: 91
Issue: 4
Pages: 640-8
Publication
First Author: Seillet C
Year: 2014
Journal: J Exp Med
Title: Nfil3 is required for the development of all innate lymphoid cell subsets.
Volume: 211
Issue: 9
Pages: 1733-40
Publication
First Author: Price AE
Year: 2012
Journal: PLoS One
Title: Marking and quantifying IL-17A-producing cells in vivo.
Volume: 7
Issue: 6
Pages: e39750
Publication
First Author: Ichiyama K
Year: 2008
Journal: J Biol Chem
Title: Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat.
Volume: 283
Issue: 25
Pages: 17003-8
Publication
First Author: Bando JK
Year: 2015
Journal: Nat Immunol
Title: Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine.
Volume: 16
Issue: 2
Pages: 153-60
Publication
First Author: Billon C
Year: 2019
Journal: J Biol Chem
Title: RORγ regulates the NLRP3 inflammasome.
Volume: 294
Issue: 1
Pages: 10-19
Publication
First Author: Ivanov II
Year: 2006
Journal: Cell
Title: The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.
Volume: 126
Issue: 6
Pages: 1121-33
Publication
First Author: Lee SM
Year: 2015
Journal: Hepatology
Title: Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism.
Volume: 61
Issue: 2
Pages: 497-505
Publication
First Author: Liu C
Year: 2007
Journal: Nature
Title: Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism.
Volume: 447
Issue: 7143
Pages: 477-81
Publication
First Author: Zhou L
Year: 2008
Journal: Nature
Title: TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function.
Volume: 453
Issue: 7192
Pages: 236-40
Publication
First Author: Xie H
Year: 2005
Journal: J Immunol
Title: RORgammat recruits steroid receptor coactivators to ensure thymocyte survival.
Volume: 175
Issue: 6
Pages: 3800-9
Publication
First Author: Villey I
Year: 1999
Journal: Eur J Immunol
Title: RORgammaT, a thymus-specific isoform of the orphan nuclear receptor RORgamma / TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoter.
Volume: 29
Issue: 12
Pages: 4072-80
Publication
First Author: Yu Y
Year: 2013
Journal: J Immunol
Title: Cutting edge: Leptin-induced RORγt expression in CD4+ T cells promotes Th17 responses in systemic lupus erythematosus.
Volume: 190
Issue: 7
Pages: 3054-8
Publication
First Author: Hatfield JK
Year: 2015
Journal: Cell Immunol
Title: Group 3 innate lymphoid cells accumulate and exhibit disease-induced activation in the meninges in EAE.
Volume: 297
Issue: 2
Pages: 69-79
Publication
First Author: Ichikawa T
Year: 2019
Journal: Nat Immunol
Title: CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells.
Volume: 20
Issue: 11
Pages: 1469-1480
Publication
First Author: Kathania M
Year: 2016
Journal: Nat Immunol
Title: Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitination.
Volume: 17
Issue: 8
Pages: 997-1004
Publication
First Author: Halim TY
Year: 2012
Journal: Immunity
Title: Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation.
Volume: 37
Issue: 3
Pages: 463-74
Publication
First Author: Schmolka N
Year: 2013
Journal: Nat Immunol
Title: Epigenetic and transcriptional signatures of stable versus plastic differentiation of proinflammatory γδ T cell subsets.
Volume: 14
Issue: 10
Pages: 1093-1100
Publication
First Author: Kawano Y
Year: 2022
Journal: Cell
Title: Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome.
Volume: 185
Issue: 19
Pages: 3501-3519.e20
Publication
First Author: Shibata K
Year: 2011
Journal: Blood
Title: Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.
Volume: 118
Issue: 3
Pages: 586-93
Publication
First Author: Reis BS
Year: 2022
Journal: Science
Title: TCR-Vγδ usage distinguishes protumor from antitumor intestinal γδ T cell subsets.
Volume: 377
Issue: 6603
Pages: 276-284
Publication
First Author: Nemoto Y
Year: 2013
Journal: J Immunol
Title: Th1/Th17-mediated interstitial pneumonia in chronic colitis mice independent of intestinal microbiota.
Volume: 190
Issue: 12
Pages: 6616-25
Publication
First Author: Hager E
Year: 2007
Journal: J Immunol
Title: Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development.
Volume: 179
Issue: 4
Pages: 2228-34
Publication
First Author: Codarri L
Year: 2011
Journal: Nat Immunol
Title: RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.
Volume: 12
Issue: 6
Pages: 560-7
Publication
First Author: Kotov JA
Year: 2019
Journal: J Exp Med
Title: BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors.
Volume: 216
Issue: 6
Pages: 1450-1464
Publication
First Author: Zhou L
Year: 2007
Journal: Nat Immunol
Title: IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.
Volume: 8
Issue: 9
Pages: 967-74
Publication
First Author: Sanos SL
Year: 2009
Journal: Nat Immunol
Title: RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells.
Volume: 10
Issue: 1
Pages: 83-91
Publication
First Author: Schmutz S
Year: 2009
Journal: J Immunol
Title: Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells.
Volume: 183
Issue: 4
Pages: 2217-21
Publication
First Author: Chu C
Year: 2018
Journal: Cell Rep
Title: Anti-microbial Functions of Group 3 Innate Lymphoid Cells in Gut-Associated Lymphoid Tissues Are Regulated by G-Protein-Coupled Receptor 183.
Volume: 23
Issue: 13
Pages: 3750-3758
Publication
First Author: Bel S
Year: 2017
Journal: Science
Title: Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine.
Volume: 357
Issue: 6355
Pages: 1047-1052
Publication
First Author: Egan CE
Year: 2016
Journal: J Clin Invest
Title: Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis.
Volume: 126
Issue: 2
Pages: 495-508
Publication
First Author: Zhang D
Year: 2019
Journal: Immunity
Title: High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation.
Volume: 51
Issue: 4
Pages: 671-681.e5
Publication
First Author: Henao-Mejia J
Year: 2013
Journal: Immunity
Title: The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis.
Volume: 38
Issue: 5
Pages: 984-97
Publication
First Author: Castro-Dopico T
Year: 2020
Journal: Cell Rep
Title: GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.
Volume: 32
Issue: 1
Pages: 107857
Publication
First Author: Sen S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.
Volume: 115
Issue: 3
Pages: E458-E467
Publication
First Author: Okubo Y
Year: 2019
Journal: Int Immunol
Title: Generation of a common innate lymphoid cell progenitor requires interferon regulatory factor 2.
Volume: 31
Issue: 8
Pages: 489-498
Publication
First Author: Qiu J
Year: 2012
Journal: Immunity
Title: The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells.
Volume: 36
Issue: 1
Pages: 92-104
Publication
First Author: Lee JS
Year: 2011
Journal: Nat Immunol
Title: AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch.
Volume: 13
Issue: 2
Pages: 144-51
Publication
First Author: Sabet-Baktach M
Year: 2013
Journal: J Immunol
Title: Double deficiency for RORγt and T-bet drives Th2-mediated allograft rejection in mice.
Volume: 191
Issue: 8
Pages: 4440-6