Type |
Details |
Score |
Allele |
Name: |
SAP30 binding protein; gene trap OST335501, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST337048, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST357660, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST357986, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST376267, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST399685, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST404775, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST414043, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap OST421921, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap XP0089, Wellcome Trust Sanger Institute |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap W073C07, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST1379, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST1402, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST1807, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST2100, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST2260, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST2405, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST2415, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST2792, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST2800, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST5909, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST5726, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST5770, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST8278, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST8832, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST9011, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST9017, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap PST9159, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap EUCE0156h11, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap EUCE318g09, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap EUCE0292a12, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap EUCE0063g03, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap EUCE0074e11, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap 37v-354, Yasumasa Ishida |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap K16, H Earl Ruley |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap HM17-1, H Earl Ruley |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap HE48U, H Earl Ruley |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap HE48R, H Earl Ruley |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap E20T, H Earl Ruley |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; transgene lentiviral insertion 2375C-1, Paul A Overbeek |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; endonuclease-mediated mutation 1, Baylor College of Medicine |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; endonuclease-mediated mutation 2, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
SAP30 is a subunit of the histone deacetylase complex. This C-terminal domain of the SAP30 proteins appears to be the binding region for Sin3 []. |
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap IST11599F6, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap IST11535D11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap IST12387H3, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein, opposite strand; gene trap IST13053G10, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap 341H9, Centre for Modeling Human Disease |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap IST10462G11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap IST14722E2, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap IST14907F11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
SAP30 binding protein; gene trap IST15105B5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant strain, coisogenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, transgenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sap30bp/Sap30bp |
Background: |
FVB/N-Sap30bp |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This C-terminal domain of the SAP30 proteins appears to be the binding region for Sin3 []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2001 |
Journal: |
J Virol |
Title: |
Epstein-Barr virus BamHi-a rightward transcript-encoded RPMS protein interacts with the CBF1-associated corepressor CIR to negatively regulate the activity of EBNA2 and NotchIC. |
Volume: |
75 |
Issue: |
6 |
Pages: |
2946-56 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Corepressor interacting with RBPJ 1 (CIR1, also known as recepin) interacts CBF1, which is a member of the CSL family of DNA binding factors, which mediate either transcriptional repression or transcriptional activation. CIR1 binds to histone deacetylase and to SAP30 and serves as a linker between CBF1 and the histone deacetylase complex []. It interacts with a variety of proteins, including Epstein-Barr virus RPMS1 []and the NKAP transcriptional repressor of notch signaling []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Viiri KM |
Year: |
2006 |
Journal: |
Nucleic Acids Res |
Title: |
SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus. |
Volume: |
34 |
Issue: |
11 |
Pages: |
3288-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grimes JA |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. |
Volume: |
275 |
Issue: |
13 |
Pages: |
9461-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duong HA |
Year: |
2011 |
Journal: |
Science |
Title: |
A molecular mechanism for circadian clock negative feedback. |
Volume: |
332 |
Issue: |
6036 |
Pages: |
1436-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi X |
Year: |
2012 |
Journal: |
Mol Cell Biochem |
Title: |
Sin3 interacts with Foxk1 and regulates myogenic progenitors. |
Volume: |
366 |
Issue: |
1-2 |
Pages: |
251-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rao G |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1. |
Volume: |
12 |
Issue: |
5 |
Pages: |
1165-72 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Sin3a is a transcriptional repressor and a homologue of the SIN3 repressor from yeast. Sin3a associates with the strong repressive isoform of Mxi1, a helix-loop-helix leucone zipper that associates with Max to antagonize Myc oncogenic activities []. Unlike Mxi1 and Myc, expression of Sin3a does not vary during development []. Sin3a is a component of several complexes, including the REST-CoREST repressor complex [], the PER complex which maintains circadian rhythm []and the Sin3 HDAC complex []. Sin3a also interacts with FOXK1 to regulate cell cycle progression []. Sin3a has three PAH domains by which it interacts with HCFC1, REST and SAP30 [, ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
450
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsieh JJ |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. |
Volume: |
96 |
Issue: |
1 |
Pages: |
23-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Maita H |
Year: |
2005 |
Journal: |
Exp Cell Res |
Title: |
CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing. |
Volume: |
303 |
Issue: |
2 |
Pages: |
375-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hazbun TR |
Year: |
2003 |
Journal: |
Mol Cell |
Title: |
Assigning function to yeast proteins by integration of technologies. |
Volume: |
12 |
Issue: |
6 |
Pages: |
1353-65 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a 45 residue conserved domain found at the N-terminal end CIR protein (CBF1-interacting co-repressor, also known as corepressor interacting with RBPJ 1). This domain can be found in the fungal CWC25 family members and mammlian LENG1 (leukocyte receptor cluster member 1) protein.CBF1 (centromere-binding factor 1) acts as a transcription factor that causes repression by binding specifically to GTGGGAA motifs in responsive promoters, and it requires CIR as a co-repressor. CIR binds to histone deacetylase and to SAP30 and serves as a linker between CBF1 and the histone deacetylase complex []. CIR also plays a role in alternative splicing []. Budding yeast Cwc25 is a pre-mRNA-splicing factor involved in pre-mRNA splicing []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Overbeek PA |
Year: |
2011 |
Journal: |
MGI Direct Data Submission |
Title: |
Direct Data Submission for Overbeek Lentiviral Transgenic Lines |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
416
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
206
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
371
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Fleischer TC |
Year: |
2003 |
Journal: |
Mol Cell Biol |
Title: |
Identification and characterization of three new components of the mSin3A corepressor complex. |
Volume: |
23 |
Issue: |
10 |
Pages: |
3456-67 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
311
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Pajerowski AG |
Year: |
2009 |
Journal: |
Immunity |
Title: |
NKAP is a transcriptional repressor of notch signaling and is required for T cell development. |
Volume: |
30 |
Issue: |
5 |
Pages: |
696-707 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
133
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1274
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Trost M |
Year: |
2009 |
Journal: |
Immunity |
Title: |
The phagosomal proteome in interferon-gamma-activated macrophages. |
Volume: |
30 |
Issue: |
1 |
Pages: |
143-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and VEGA Genome Database Project |
Year: |
2006 |
Journal: |
Database Release |
Title: |
Collaboration to Associate VEGA (Vertebrate Genome Annotation) Mouse Gene Models with MGI Markers |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
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Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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