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Search results 301 to 322 out of 322 for Sema7a

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Type Details Score
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Sema7a<em3Smoc> | MGI:6511749
Name: sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Tg(Sema7a-cre)NO117Gsat | MGI:5086194
Name: transgene insertion NO117, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:5519917 | STOCK Tg(Sema7a-cre)NO117Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Protein Domain
IPR042824 | Sema7A_sema
Type: Domain
Description: Semaphorin-7A (Sema7A) plays regulatory roles in both immune and nervous systems. Unlike other semaphorins, which act as repulsive guidance cues, Sema7A enhances central and peripheral axon growth and is required for proper axon tract formation during embryonic development []. Sema7A also plays a critical role in the negative regulation of T cell activation and function []. Sema7A is a membrane-anchored member of the semaphorin family of proteins. Semaphorins are regulatory molecules in the development of the nervous system and in axonal guidance. They also play important roles in other biological processes, such as angiogenesis, immune regulation, respiration systems and cancer. The Sema domain is located at the N terminus and contains four disulfide bonds formed by eight conserved cysteine residues. It serves as a receptor-recognition and -binding module [].
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Publication
10520995 | J:57949
First Author: Tamagnone L
Year: 1999
Journal: Cell
Title: Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.
Volume: 99
Issue: 1
Pages: 71-80
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HT Experiment
GSE190010 | RNA-seq analysis dataset: Cerebellum tissues from wild type and Dscam del17/del17 mice at P21
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
23648820 | J:202138
First Author: Linder GE
Year: 2013
Journal: Cell Immunol
Title: Semaphorin 4A is dynamically regulated during thymocyte development in mice.
Volume: 281
Issue: 2
Pages: 150-8
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Publication
19318806 | -
First Author: Lazova R
Year: 2009
Journal: Am J Dermatopathol
Title: The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis.
Volume: 31
Issue: 2
Pages: 177-81
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Publication
18987670 | -
First Author: Scott GA
Year: 2009
Journal: J Invest Dermatol
Title: Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression.
Volume: 129
Issue: 4
Pages: 954-63
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Protein Domain
IPR041853 | Plexin-C1_Sema
Type: Domain
Description: This entry represents the Sema domain found in Plexin-C1, which belongs to the Plexin family. Plexin family members are semaphorin receptors. Plexin C1 has been identified as the receptor of semaphorin 7A, which plays regulation roles in both the immune and nervous systems []. Unlike other semaphorins which act as repulsive guidance cues, Sema7A enhances central and peripheral axon growth and is required for proper axon tract formation during embryonic development. Plexin C1 is a potential tumor suppressor for melanoma progression. The expression of Plexin C1 is diminished or absent in human melanoma cell lines []. Cofilin, an actin-binding protein involved in cell migration, is a downstream target of Sema7A-Plexin C1 signaling. Cofilin is not phosphorylated when Plexin C1 expression is silenced. Thus, melanoma invasion and metastasis may be promoted through the loss of Plexin C1 inhibitory signaling on cofilin activation []. The Sema domain is located at the N terminus and contains four disulfide bonds formed by eight conserved cysteine residues. It serves as a ligand-recognition and -binding module.
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Publication
37941899 | J:342384
 
First Author: Emery A
Year: 2023
Journal: Front Cell Dev Biol
Title: Dynamic regulation of semaphorin 7A and adhesion receptors in ovarian follicle remodeling and ovulation.
Volume: 11
Pages: 1261038
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Publication
28792937 | J:253064
First Author: Lee H
Year: 2017
Journal: Nature
Title: Rewiring the taste system.
Volume: 548
Issue: 7667
Pages: 330-333
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Publication
38094294 | J:343681
 
First Author: Körner A
Year: 2023
Journal: Front Immunol
Title: Semaphorin 7A is protective during inflammatory peritonitis through integrin receptor signaling.
Volume: 14
Pages: 1251026
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Publication
16584533 | -
First Author: Yazdani U
Year: 2006
Journal: Genome Biol
Title: The semaphorins.
Volume: 7
Issue: 3
Pages: 211
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Protein
Q9QUR8
Organism: Mus musculus/domesticus
Length: 664  
Fragment?: false
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Protein
Q9QZC2
Organism: Mus musculus/domesticus
Length: 1574  
Fragment?: false
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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