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Search results 301 to 400 out of 805 for Serpine1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5439162
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5440237
Age: postnatal adult
Note: Expressed in decidual tissue only.
Specimen Label: not shown
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5440077
Age: postnatal adult
Image: 1R maternal
Note: Expressed in decidual cells adjacent to the ectoplacental cone. In the area of placenta formation, expression was in the decidual tissue neighboring trophoblast giant cells.
Specimen Label: 1R maternal
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5440077
Age: postnatal adult
Image: 1W maternal
Note: Expressed in decidua vascularis cells.
Specimen Label: 1W maternal
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5440077
Age: postnatal adult
Image: 9B maternal
Note: Expression in this mutant is the same as in wild-type embryos.
Specimen Label: 9B maternal
Detected: true
Specimen Num: 14
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5440077
Age: postnatal adult
Note: Expressed in decidual cells adjacent to the ectoplacental cone. In the area of placenta formation, expression was in the decidual tissue neighboring trophoblast giant cells. Expression in this mutant is the same as in wild-type embryos.
Specimen Label: not shown maternal
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2991728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5440077
Age: postnatal adult
Image: 9B maternal
Note: Expression in this mutant is the same as in wild-type embryos.
Specimen Label: 9B maternal
Detected: true
Specimen Num: 14
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160539
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:5440077
Age: embryonic day 6.5
Image: 1H embryo
Specimen Label: 1H embryo
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1605311
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5440077
Age: embryonic day 7.5
Image: 1M embryo
Note: Expression is the same as in E6.5 embryos.
Specimen Label: 1M embryo
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:4416180
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1860123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827999
Age: embryonic day 14.5
Image: euxassay_012476_09
Specimen Label: euxassay_012476_09
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4416180
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1860123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827999
Age: embryonic day 14.5
Image: euxassay_012476_10
Specimen Label: euxassay_012476_10
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4416180
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1860123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827999
Age: embryonic day 14.5
Image: euxassay_012476_11
Specimen Label: euxassay_012476_11
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4416180
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1860123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827999
Age: embryonic day 14.5
Image: euxassay_012476_12
Specimen Label: euxassay_012476_12
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4416180
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1860123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827999
Age: embryonic day 14.5
Image: euxassay_012476_13
Specimen Label: euxassay_012476_13
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187713
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5440077
Age: embryonic day 8.5
Image: 1R embryo
Note: Expressed in the trophoblast giant cells surrounding the embryonic cavity and the area of placenta formation.
Specimen Label: 1R embryo
Detected: true
Specimen Num: 6
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187713
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5440077
Age: embryonic day 8.5
Image: 2I
Note: Expressed in the trophoblast giant cells surrounding the embryonic cavity.
Specimen Label: 2I
Detected: true
Specimen Num: 12
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•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187713
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5440077
Age: embryonic day 8.5
Note: Expressed in the trophoblast giant cells surrounding the embryonic cavity and the area of placenta formation. Expression in this mutant is the same as in wild-type embryos.
Specimen Label: not shown embryo
Detected: true
Specimen Num: 15
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•
GXD Expression
GXD Expression
 
Probe: MGI:5439162
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187713
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5440237
Age: embryonic day 8.5
Image: 5E embryo
Specimen Label: 5E embryo
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:6716074
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6716084
Age: embryonic day 18.5
Specimen Label: 5A +/+
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:6716074
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287426
Stage: TS26
Assay Id: MGI:6716084
Age: embryonic day 18.5
Note: In the mutant expression is significantly reduced.
Specimen Label: 5A -/-
Detected: false
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1606711
Stage: TS11
Assay Id: MGI:5440077
Age: embryonic day 7.5
Image: 2C
Note: No expression in ectoplacental cone trophoblast cells.
Specimen Label: 2C
Detected: false
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1606711
Stage: TS11
Assay Id: MGI:5440077
Age: embryonic day 7.5
Image: 9B embryo
Note: No expression in ectoplacental cone trophoblast cells. Expression in this mutant is the same as in wild-type embryos.
Specimen Label: 9B embryo
Detected: false
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439162
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5440237
Age: postnatal adult
Image: 5E maternal
Specimen Label: 5E maternal
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439162
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5440237
Age: postnatal adult
Image: 5D maternal
Specimen Label: 5D maternal
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5440077
Age: embryonic day 9.5
Image: 1W embryo
Specimen Label: 1W embryo
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1606811
Stage: TS11
Assay Id: MGI:5440077
Age: embryonic day 7.5
Image: 2C
Note: No expression in ectoplacental cone trophoblast cells.
Specimen Label: 2C
Detected: false
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1606811
Stage: TS11
Assay Id: MGI:5440077
Age: embryonic day 7.5
Image: 9B embryo
Note: No expression in ectoplacental cone trophoblast cells. Expression in this mutant is the same as in wild-type embryos.
Specimen Label: 9B embryo
Detected: false
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5440077
Age: postnatal adult
Note: No expression in non-pregnant uterus.
Specimen Label: not shown
Detected: false
Specimen Num: 17
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5439026
Assay Type: RNA in situ
Annotation Date: 2012-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3187613
Stage: TS13
Assay Id: MGI:5440077
Age: embryonic day 8.5
Image: 1R embryo
Specimen Label: 1R embryo
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5439162
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3187613
Stage: TS13
Assay Id: MGI:5440237
Age: embryonic day 8.5
Image: 5D embryo
Specimen Label: 5D embryo
Detected: false
Specimen Num: 1
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Publication
23686362 | J:323804
First Author: Sandri M
Year: 2013
Journal: Biogerontology
Title: Signalling pathways regulating muscle mass in ageing skeletal muscle: the role of the IGF1-Akt-mTOR-FoxO pathway.
Volume: 14
Issue: 3
Pages: 303-23
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Publication
28722352 | J:248177
First Author: Jiang C
Year: 2017
Journal: Aging Cell
Title: Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic lung disease.
Volume: 16
Issue: 5
Pages: 1114-1124
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Publication
17415547 | J:141728
First Author: Lassila M
Year: 2007
Journal: Diabetologia
Title: Plasminogen activator inhibitor-1 production is pathogenetic in experimental murine diabetic renal disease.
Volume: 50
Issue: 6
Pages: 1315-26
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Publication
1695900 | J:320134
First Author: Ehrlich HJ
Year: 1990
Journal: J Biol Chem
Title: Alteration of serpin specificity by a protein cofactor. Vitronectin endows plasminogen activator inhibitor 1 with thrombin inhibitory properties.
Volume: 265
Issue: 22
Pages: 13029-35
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Publication
1698787 | J:320135
First Author: Preissner KT
Year: 1990
Journal: J Biol Chem
Title: Structural requirements for the extracellular interaction of plasminogen activator inhibitor 1 with endothelial cell matrix-associated vitronectin.
Volume: 265
Issue: 30
Pages: 18490-8
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Publication
17888748 | J:145103
First Author: Nordstrom SM
Year: 2007
Journal: Bone
Title: Transgenic over-expression of plasminogen activator inhibitor-1 results in age-dependent and gender-specific increases in bone strength and mineralization.
Volume: 41
Issue: 6
Pages: 995-1004
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Publication
32024545 | J:320385
First Author: Furuya H
Year: 2020
Journal: J Transl Med
Title: Plasminogen activator inhibitor-2 (PAI-2) overexpression supports bladder cancer development in PAI-1 knockout mice in N-butyl-N- (4-hydroxybutyl)-nitrosamine- induced bladder cancer mouse model.
Volume: 18
Issue: 1
Pages: 57
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Publication
9427542 | J:44614
First Author: Zhang Q
Year: 1997
Journal: Gene
Title: Molecular cloning and characterization of P113, a mouse SNF2/SWI2-related transcription factor.
Volume: 202
Issue: 1-2
Pages: 31-7
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Publication
15328353 | J:94483
First Author: Hobson JP
Year: 2004
Journal: J Biol Chem
Title: Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes.
Volume: 279
Issue: 45
Pages: 46981-94
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Publication
8939962 | J:36876
First Author: Lang IM
Year: 1996
Journal: J Biol Chem
Title: Purification of storage granule protein-23. A novel protein identified by phage display technology and interaction with type I plasminogen activator inhibitor.
Volume: 271
Issue: 47
Pages: 30126-35
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Publication
18216319 | J:149930
First Author: Huang Y
Year: 2008
Journal: J Am Soc Nephrol
Title: A PAI-1 mutant, PAI-1R, slows progression of diabetic nephropathy.
Volume: 19
Issue: 2
Pages: 329-38
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Publication
9119016 | J:39196
First Author: Ny A
Year: 1997
Journal: Eur J Biochem
Title: Studies of mice lacking plasminogen activator gene function suggest that plasmin production prior to ovulation exceeds the amount needed for optimal ovulation efficiency.
Volume: 244
Issue: 2
Pages: 487-93
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Publication
16314510 | J:103766
First Author: Buchwalter G
Year: 2005
Journal: Mol Cell Biol
Title: The ternary complex factor Net regulates cell migration through inhibition of PAI-1 expression.
Volume: 25
Issue: 24
Pages: 10853-62
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Publication
24425831 | J:333632
First Author: Komiya M
Year: 2014
Journal: In Vivo
Title: Bi-directional regulation between adiponectin and plasminogen activator-inhibitor-1 in 3T3-L1 cells.
Volume: 28
Issue: 1
Pages: 13-9
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Publication
19745198 | J:167796
First Author: Numaguchi Y
Year: 2009
Journal: Arterioscler Thromb Vasc Biol
Title: Ablation of angiotensin IV receptor attenuates hypofibrinolysis via PAI-1 downregulation and reduces occlusive arterial thrombosis.
Volume: 29
Issue: 12
Pages: 2102-8
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Publication
22078208 | J:185109
First Author: Thapa B
Year: 2012
Journal: Mol Immunol
Title: Novel regulatory mechanism and functional implication of plasminogen activator inhibitor-1 (PAI-1) expression in CpG-ODN-stimulated macrophages.
Volume: 49
Issue: 4
Pages: 572-81
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Publication
21969564 | J:177452
First Author: Geh E
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure.
Volume: 108
Issue: 42
Pages: 17349-54
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Publication
17022820 | J:114074
 
First Author: Hoover-Plow J
Year: 2006
Journal: BMC Blood Disord
Title: Genetic background determines response to hemostasis and thrombosis.
Volume: 6
Pages: 6
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Publication
25587125 | J:282749
First Author: Kobayashi N
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Podocyte injury-driven intracapillary plasminogen activator inhibitor type 1 accelerates podocyte loss via uPAR-mediated β1-integrin endocytosis.
Volume: 308
Issue: 6
Pages: F614-26
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Publication
8397803 | J:16546
First Author: Liu YX
Year: 1993
Journal: Sci China B
Title: Hormonal regulation of tissue-type plasminogen activator and plasminogen activator inhibitor type-1 gene expression in cultured mouse Sertoli cells.
Volume: 36
Issue: 3
Pages: 319-28
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Publication
18614541 | J:141873
First Author: Kortlever RM
Year: 2008
Journal: J Biol Chem
Title: Transforming growth factor-beta requires its target plasminogen activator inhibitor-1 for cytostatic activity.
Volume: 283
Issue: 36
Pages: 24308-13
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Publication
18723692 | J:142267
First Author: Tjwa M
Year: 2008
Journal: Blood
Title: Plasmin therapy enhances mobilization of HPCs after G-CSF.
Volume: 112
Issue: 10
Pages: 4048-50
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Publication
20630999 | J:165685
First Author: Sangle GV
Year: 2010
Journal: Endocrinology
Title: Involvement of RAGE, NADPH oxidase, and Ras/Raf-1 pathway in glycated LDL-induced expression of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells.
Volume: 151
Issue: 9
Pages: 4455-66
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Publication
23657855 | J:198743
First Author: Kim JI
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Gender-specific role of HDAC11 in kidney ischemia- and reperfusion-induced PAI-1 expression and injury.
Volume: 305
Issue: 1
Pages: F61-70
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Publication
18258607 | J:133497
First Author: Mutoh M
Year: 2008
Journal: Carcinogenesis
Title: Plasminogen activator inhibitor-1 (Pai-1) blockers suppress intestinal polyp formation in Min mice.
Volume: 29
Issue: 4
Pages: 824-9
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Publication
17429342 | J:152739
First Author: Brown NJ
Year: 2007
Journal: Kidney Int
Title: Modulation of angiotensin II and norepinephrine-induced plasminogen activator inhibitor-1 expression by AT1a receptor deficiency.
Volume: 72
Issue: 1
Pages: 72-81
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Publication
23340304 | J:305712
First Author: Sánchez-Tilló E
Year: 2013
Journal: Clin Cancer Res
Title: ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.
Volume: 19
Issue: 5
Pages: 1071-82
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Publication
25454795 | J:220906
 
First Author: Bi Oh S
Year: 2015
Journal: Brain Res
Title: Impacts of aging and amyloid-β deposition on plasminogen activators and plasminogen activator inhibitor-1 in the Tg2576 mouse model of Alzheimer's disease.
Volume: 1597
Pages: 159-67
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Publication
28132883 | J:255374
First Author: Gerenu G
Year: 2017
Journal: Biochim Biophys Acta
Title: Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits.
Volume: 1863
Issue: 4
Pages: 991-1001
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Publication
8508955 | J:320118
First Author: Pannekoek H
Year: 1993
Journal: Gene
Title: Functional display of human plasminogen-activator inhibitor 1 (PAI-1) on phages: novel perspectives for structure-function analysis by error-prone DNA synthesis.
Volume: 128
Issue: 1
Pages: 135-40
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Publication
10992299 | J:64749
First Author: Chang WS
Year: 2000
Journal: Genes Chromosomes Cancer
Title: Tissue-specific cancer-related serpin gene cluster at human chromosome band 3q26.
Volume: 29
Issue: 3
Pages: 240-55
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Publication
8560424 | J:30002
First Author: Lijnen HR
Year: 1995
Journal: Thromb Haemost
Title: Biological effects of combined inactivation of plasminogen activator and plasminogen activator inhibitor-1 gene function in mice.
Volume: 74
Issue: 4
Pages: 1126-31
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Publication
8662686 | J:33242
First Author: Nielsen KL
Year: 1996
Journal: J Biol Chem
Title: Identification of residues in alpha-macroglobulins important for binding to the alpha2-macroglobulin receptor/Low density lipoprotein receptor-related protein.
Volume: 271
Issue: 22
Pages: 12909-12
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Publication
8816919 | J:36132
First Author: Seki T
Year: 1996
Journal: J Cell Physiol
Title: Interleukin-1 induction of type-1 plasminogen activator inhibitor (PAI-1) gene expression in the mouse hepatocyte line, AML 12.
Volume: 168
Issue: 3
Pages: 648-56
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Publication
9033272 | J:38287
First Author: Fearns C
Year: 1997
Journal: Am J Pathol
Title: Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha.
Volume: 150
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