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Search results 301 to 400 out of 459 for Shank3

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:7430980
Assay Type: RNA in situ
Annotation Date: 2023-02-01
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7430989
Age: embryonic day 18.0
Image: E18
Specimen Label: E18
Detected: true
Specimen Num: 2
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Publication
- | J:67165
   
First Author: Dehmelt L
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for Shank3b protein (shank3 gene)
Pages: AJ245904
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Publication
22699619 | J:186719
First Author: Schmeisser MJ
Year: 2012
Journal: Nature
Title: Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Volume: 486
Issue: 7402
Pages: 256-60
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Publication
31624228 | J:294529
First Author: Oron O
Year: 2019
Journal: Transl Psychiatry
Title: Gene network analysis reveals a role for striatal glutamatergic receptors in dysregulated risk-assessment behavior of autism mouse models.
Volume: 9
Issue: 1
Pages: 257
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Publication
32853769 | J:331666
First Author: Nuzzo T
Year: 2020
Journal: Biochim Biophys Acta Proteins Proteom
Title: Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism.
Volume: 1868
Issue: 12
Pages: 140531
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Publication
37699442 | J:341243
 
First Author: Ciancone-Chama AG
Year: 2023
Journal: Neuroscience
Title: Gene Expression Profiling in Trigeminal Ganglia from Cntnap2(-/-) and Shank3b(-/-) Mouse Models of Autism Spectrum Disorder.
Volume: 531
Pages: 75-85
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Publication
32445272 | J:308757
First Author: Kabitzke P
Year: 2020
Journal: Genes Brain Behav
Title: Mouse model systems of autism spectrum disorder: Replicability and informatics signature.
Volume: 19
Issue: 7
Pages: e12676
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Publication
31891524 | J:308758
First Author: Geramita MA
Year: 2020
Journal: J Neurophysiol
Title: Decreased amplitude and reliability of odor-evoked responses in two mouse models of autism.
Volume: 123
Issue: 4
Pages: 1283-1294
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Publication
38177238 | J:344447
First Author: Tripathi MK
Year: 2024
Journal: Sci Rep
Title: Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain.
Volume: 14
Issue: 1
Pages: 10
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Publication
29804286 | J:265246
First Author: Lautz JD
Year: 2018
Journal: J Neurochem
Title: Synaptic activity induces input-specific rearrangements in a targeted synaptic protein interaction network.
Volume: 146
Issue: 5
Pages: 540-559
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Publication
33947797 | J:312285
 
First Author: Heavner WE
Year: 2021
Journal: Sci Signal
Title: Remodeling of the Homer-Shank interactome mediates homeostatic plasticity.
Volume: 14
Issue: 681
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Publication
36450249 | J:332181
First Author: Ma B
Year: 2022
Journal: Cell Rep
Title: Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios.
Volume: 41
Issue: 9
Pages: 111722
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Publication
35580019 | J:324692
   
First Author: Kuga N
Year: 2022
Journal: Elife
Title: Prefrontal-amygdalar oscillations related to social behavior in mice.
Volume: 11
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Publication
35618950 | J:335651
First Author: Bian WJ
Year: 2022
Journal: Nat Neurosci
Title: Adolescent sleep shapes social novelty preference in mice.
Volume: 25
Issue: 7
Pages: 912-923
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Publication
38657057 | J:348257
First Author: Rein B
Year: 2024
Journal: Sci Adv
Title: MDMA enhances empathy-like behaviors in mice via 5-HT release in the nucleus accumbens.
Volume: 10
Issue: 17
Pages: eadl6554
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Publication
30655440 | J:273335
First Author: Corder G
Year: 2019
Journal: Science
Title: An amygdalar neural ensemble that encodes the unpleasantness of pain.
Volume: 363
Issue: 6424
Pages: 276-281
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Publication
32024781 | J:286384
First Author: Resendez SL
Year: 2020
Journal: J Neurosci
Title: Social Stimuli Induce Activation of Oxytocin Neurons Within the Paraventricular Nucleus of the Hypothalamus to Promote Social Behavior in Male Mice.
Volume: 40
Issue: 11
Pages: 2282-2295
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Publication
27199660 | J:240209
 
First Author: Heise C
Year: 2016
Journal: Front Cell Neurosci
Title: Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.
Volume: 10
Pages: 106
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Publication
20800661 | J:169788
First Author: Raab M
Year: 2010
Journal: Neuroscience
Title: Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system.
Volume: 171
Issue: 2
Pages: 421-33
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Publication
38124211 | J:354122
 
First Author: Pan YD
Year: 2024
Journal: J Neurosci
Title: Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.
Volume: 44
Issue: 7
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Publication
39366951 | J:354983
First Author: Gora C
Year: 2024
Journal: Transl Psychiatry
Title: Deciphering autism heterogeneity: a molecular stratification approach in four mouse models.
Volume: 14
Issue: 1
Pages: 416
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Publication
27428651 | J:238123
First Author: Shemesh Y
Year: 2016
Journal: Nat Neurosci
Title: Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics.
Volume: 19
Issue: 11
Pages: 1489-1496
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Publication
30116174 | J:266519
 
First Author: Lauber E
Year: 2018
Journal: Front Mol Neurosci
Title: Dysregulation of Parvalbumin Expression in the Cntnap2-/- Mouse Model of Autism Spectrum Disorder.
Volume: 11
Pages: 262
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Publication
26819149 | J:259439
 
First Author: Filice F
Year: 2016
Journal: Mol Brain
Title: Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism.
Volume: 9
Pages: 10
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Publication
30522820 | J:269351
First Author: Sgritta M
Year: 2019
Journal: Neuron
Title: Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder.
Volume: 101
Issue: 2
Pages: 246-259.e6
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Publication
23583105 | J:197901
First Author: Jiang YH
Year: 2013
Journal: Neuron
Title: Modeling autism by SHANK gene mutations in mice.
Volume: 78
Issue: 1
Pages: 8-27
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Publication
30838762 | J:293942
First Author: Ponzoni L
Year: 2019
Journal: Genes Brain Behav
Title: Different attentional dysfunctions in eEF2K-/- , IL1RAPL1-/- and SHANK3Δ11-/- mice.
Volume: 18
Issue: 5
Pages: e12563
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Publication
25088363 | J:221545
First Author: Gogolla N
Year: 2014
Journal: Neuron
Title: Sensory integration in mouse insular cortex reflects GABA circuit maturation.
Volume: 83
Issue: 4
Pages: 894-905
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Publication
30797034 | J:314834
 
First Author: Angelakos CC
Year: 2019
Journal: Neurobiol Learn Mem
Title: Home-cage hypoactivity in mouse genetic models of autism spectrum disorder.
Volume: 165
Pages: 107000
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Publication
15689540 | J:98257
First Author: Olson PA
Year: 2005
Journal: J Neurosci
Title: G-protein-coupled receptor modulation of striatal CaV1.3 L-type Ca2+ channels is dependent on a Shank-binding domain.
Volume: 25
Issue: 5
Pages: 1050-62
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Publication
21653829 | J:173460
First Author: Sakai Y
Year: 2011
Journal: Sci Transl Med
Title: Protein interactome reveals converging molecular pathways among autism disorders.
Volume: 3
Issue: 86
Pages: 86ra49
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Publication
23142422 | J:192363
First Author: Olexová L
Year: 2012
Journal: Neurosci Res
Title: Animal models of autism with a particular focus on the neural basis of changes in social behaviour: an update article.
Volume: 74
Issue: 3-4
Pages: 184-94
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Publication
30237867 | J:308760
 
First Author: Brown EA
Year: 2018
Journal: Mol Autism
Title: Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.
Volume: 9
Pages: 48
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Publication
31853066 | J:289937
First Author: Reed MD
Year: 2020
Journal: Nature
Title: IL-17a promotes sociability in mouse models of neurodevelopmental disorders.
Volume: 577
Issue: 7789
Pages: 249-253
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Publication
35021077 | J:321505
First Author: Sheppard K
Year: 2022
Journal: Cell Rep
Title: Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation.
Volume: 38
Issue: 2
Pages: 110231
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Publication
27293187 | J:232023
First Author: Orefice LL
Year: 2016
Journal: Cell
Title: Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs.
Volume: 166
Issue: 2
Pages: 299-313
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Publication
27080031 | J:266755
 
First Author: Petrinovic MM
Year: 2016
Journal: Sci Rep
Title: A novel anesthesia regime enables neurofunctional studies and imaging genetics across mouse strains.
Volume: 6
Pages: 24523
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Publication
26158416 | J:225991
 
First Author: Kloth AD
Year: 2015
Journal: Elife
Title: Cerebellar associative sensory learning defects in five mouse autism models.
Volume: 4
Pages: e06085
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Publication
32126198 | J:292790
First Author: Tai C
Year: 2020
Journal: Neuron
Title: Tau Reduction Prevents Key Features of Autism in Mouse Models.
Volume: 106
Issue: 3
Pages: 421-437.e11
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Publication
15207857 | J:150922
First Author: Uemura T
Year: 2004
Journal: Mol Cell Neurosci
Title: Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.
Volume: 26
Issue: 2
Pages: 330-41
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Publication
30319350 | J:266512
 
First Author: Berkel S
Year: 2018
Journal: Front Mol Neurosci
Title: Sex Hormones Regulate SHANK Expression.
Volume: 11
Pages: 337
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Publication
33374598 | J:348434
 
First Author: Eltokhi A
Year: 2020
Journal: Int J Mol Sci
Title: Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies.
Volume: 22
Issue: 1
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Publication
23010509 | J:221700
 
First Author: Schwartzer JJ
Year: 2013
Journal: Neurotoxicol Teratol
Title: Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.
Volume: 36
Pages: 17-35
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Publication
27979975 | J:239308
First Author: Chen CY
Year: 2017
Journal: EMBO Rep
Title: TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology.
Volume: 18
Issue: 1
Pages: 169-183
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Publication
27779093 | J:238731
   
First Author: Harrington AJ
Year: 2016
Journal: Elife
Title: MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.
Volume: 5
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Publication
26627310 | J:228732
First Author: Berg JM
Year: 2015
Journal: Neuron
Title: JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.
Volume: 88
Issue: 6
Pages: 1173-91
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Publication
14622142 | J:89658
First Author: Bolis A
Year: 2003
Journal: Eur J Neurosci
Title: Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation.
Volume: 18
Issue: 9
Pages: 2417-24
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Publication
23226954 | J:221699
First Author: Crawley JN
Year: 2012
Journal: Dialogues Clin Neurosci
Title: Translational animal models of autism and neurodevelopmental disorders.
Volume: 14
Issue: 3
Pages: 293-305
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Publication
28288114 | J:240674
First Author: Lu HC
Year: 2017
Journal: Nat Genet
Title: Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.
Volume: 49
Issue: 4
Pages: 527-536
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Publication
31600191 | J:280803
First Author: Ma J
Year: 2019
Journal: PLoS Biol
Title: Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.
Volume: 17
Issue: 10
Pages: e3000461
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Publication
19208628 | J:148808
First Author: Sawallisch C
Year: 2009
Journal: J Biol Chem
Title: The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Volume: 284
Issue: 14
Pages: 9225-36
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Publication
28671696 | J:249721
First Author: Li J
Year: 2017
Journal: Nat Neurosci
Title: Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
Volume: 20
Issue: 8
Pages: 1150-1161
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Publication
32492419 | J:306456
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
A0A088DEG3
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
A0A088DEG5
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
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Protein
A0A088DEG0
Organism: Mus musculus/domesticus
Length: 35  
Fragment?: true
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Protein
A0A088DEG6
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
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Publication
31983435 | J:296185
First Author: Perfitt TL
Year: 2020
Journal: Biochem Biophys Res Commun
Title: CaMKIIα phosphorylation of Shank3 modulates ABI1-Shank3 interaction.
Volume: 524
Issue: 1
Pages: 262-267
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Allele
Shank3<tm2.1Yhj> | MGI:5800310
Name: SH3 and multiple ankyrin repeat domains 3; targeted mutation 2.1, Yong-hui Jiang
Allele Type: Targeted
Attribute String: Conditional ready
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Publication
19371741 | J:150465
First Author: Huett A
Year: 2009
Journal: Exp Cell Res
Title: The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.
Volume: 315
Issue: 12
Pages: 2001-11
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HT Experiment
GSE225983 | Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(Shank3-EGFP)1Hzo | MGI:5515936
Name: transgene insertion 1, Huda Y Zoghbi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Publication
21565394 | J:173397
First Author: Bangash MA
Year: 2011
Journal: Cell
Title: Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism.
Volume: 145
Issue: 5
Pages: 758-72
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Genotype
Genotype
Symbol: Tg(Shank3-EGFP)1Hzo/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Interaction Experiment
Lee Y (2017)
Description: Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.
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Publication
30364266 | J:290049
 
First Author: Bariselli S
Year: 2018
Journal: Front Mol Neurosci
Title: SHANK3 Downregulation in the Ventral Tegmental Area Accelerates the Extinction of Contextual Associations Induced by Juvenile Non-familiar Conspecific Interaction.
Volume: 11
Pages: 360
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