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Search results 301 to 400 out of 8780 for Shh

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:6183261
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191300
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Shh
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6183261
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191300
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Shh
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6183261
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191300
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Shh
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6183261
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191300
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Shh
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6183261
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191300
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Shh
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6183261
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191300
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Shh
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6183261
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191300
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Shh
Detected: true
Specimen Num: 7
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Publication
12808456 | J:84077
First Author: Khokha MK
Year: 2003
Journal: Nat Genet
Title: Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning.
Volume: 34
Issue: 3
Pages: 303-7
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Publication
21664576 | J:173604
First Author: Allen BL
Year: 2011
Journal: Dev Cell
Title: Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.
Volume: 20
Issue: 6
Pages: 775-87
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Publication
24715461 | J:208849
First Author: Lettice LA
Year: 2014
Journal: Development
Title: Development of five digits is controlled by a bipartite long-range cis-regulator.
Volume: 141
Issue: 8
Pages: 1715-25
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Publication
18634775 | J:139045
First Author: Thomason HA
Year: 2008
Journal: Dev Biol
Title: Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling.
Volume: 321
Issue: 1
Pages: 273-82
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Publication
16145660 | J:106345
First Author: Nie X
Year: 2005
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Developmentally regulated expression of Shh and Ihh in the developing mouse cranial base: comparison with Sox9 expression.
Volume: 286
Issue: 2
Pages: 891-8
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Publication
38509385 | J:347410
First Author: Chen Z
Year: 2024
Journal: Nat Genet
Title: Increased enhancer-promoter interactions during developmental enhancer activation in mammals.
Volume: 56
Issue: 4
Pages: 675-685
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Publication
22558278 | J:231130
First Author: Dahia CL
Year: 2012
Journal: PLoS One
Title: Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc.
Volume: 7
Issue: 4
Pages: e35944
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Publication
25927436 | J:235097
First Author: Jin Y
Year: 2015
Journal: PLoS One
Title: The shh signaling pathway is upregulated in multiple cell types in cortical ischemia and influences the outcome of stroke in an animal model.
Volume: 10
Issue: 4
Pages: e0124657
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Publication
10395791 | J:56424
First Author: Goodrich LV
Year: 1999
Journal: Dev Biol
Title: Overexpression of ptc1 inhibits induction of Shh target genes and prevents normal patterning in the neural tube.
Volume: 211
Issue: 2
Pages: 323-34
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Publication
28235772 | J:247686
First Author: Standing ASI
Year: 2017
Journal: J Leukoc Biol
Title: Frontline Science: Shh production and Gli signaling is activated in vivo in lung, enhancing the Th2 response during a murine model of allergic asthma.
Volume: 102
Issue: 4
Pages: 965-976
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Publication
15668330 | J:112545
First Author: Wang XP
Year: 2005
Journal: J Dent Res
Title: Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth.
Volume: 84
Issue: 2
Pages: 138-43
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DO Term
DOID:0080703 | medulloblastoma SHH activated
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Publication
18272593 | J:132152
First Author: Chamberlain CE
Year: 2008
Journal: Development
Title: Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning.
Volume: 135
Issue: 6
Pages: 1097-106
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Publication
22396494 | J:185751
First Author: Capozza F
Year: 2012
Journal: Cancer Res
Title: Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration.
Volume: 72
Issue: 9
Pages: 2262-74
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Publication
27768887 | J:316049
First Author: Kvon EZ
Year: 2016
Journal: Cell
Title: Progressive Loss of Function in a Limb Enhancer during Snake Evolution.
Volume: 167
Issue: 3
Pages: 633-642.e11
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Publication
28793263 | J:254868
First Author: Lettice LA
Year: 2017
Journal: Cell Rep
Title: The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression.
Volume: 20
Issue: 6
Pages: 1396-1408
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Publication
16908629 | J:112237
First Author: Panman L
Year: 2006
Journal: Development
Title: Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling.
Volume: 133
Issue: 17
Pages: 3419-28
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Publication
17049204 | J:121866
First Author: Masuya H
Year: 2007
Journal: Genomics
Title: A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud.
Volume: 89
Issue: 2
Pages: 207-14
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Publication
18156157 | J:132465
First Author: Lettice LA
Year: 2008
Journal: Hum Mol Genet
Title: Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly.
Volume: 17
Issue: 7
Pages: 978-85
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Publication
23238718 | J:192019
First Author: Touahri Y
Year: 2012
Journal: J Neurosci
Title: Sulfatase 1 promotes the motor neuron-to-oligodendrocyte fate switch by activating Shh signaling in Olig2 progenitors of the embryonic ventral spinal cord.
Volume: 32
Issue: 50
Pages: 18018-34
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Publication
17707671 | J:127326
First Author: Elsaid AF
Year: 2007
Journal: Mol Genet Metab
Title: Differential perturbation of the Fgf/Erk1/2 and Shh pathways in the C57BL/6N and SWV embryonic limb buds after mid-gestational cadmium chloride administration.
Volume: 92
Issue: 3
Pages: 258-70
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Publication
14727139 | J:87798
First Author: Sagai T
Year: 2004
Journal: Mamm Genome
Title: Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh).
Volume: 15
Issue: 1
Pages: 23-34
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Publication
12455636 | J:104869
First Author: Blanc I
Year: 2002
Journal: Int J Dev Biol
Title: Unusual pattern of Sonic hedgehog expression in the polydactylous mouse mutant Hemimelic extra-toes.
Volume: 46
Issue: 7
Pages: 969-74
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Publication
12163415 | J:78220
First Author: Zhang Z
Year: 2002
Journal: Development
Title: Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis.
Volume: 129
Issue: 17
Pages: 4135-46
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Publication
9118802 | J:40390
First Author: Sasaki H
Year: 1997
Journal: Development
Title: A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro.
Volume: 124
Issue: 7
Pages: 1313-22
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Publication
23283079 | J:193837
First Author: Abdelhamed ZA
Year: 2013
Journal: Hum Mol Genet
Title: Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel-Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects.
Volume: 22
Issue: 7
Pages: 1358-72
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Publication
22572615 | J:186261
First Author: Reeder AL
Year: 2012
Journal: J Surg Res
Title: Formation of intestinal atresias in the Fgfr2IIIb-/- mice is not associated with defects in notochord development or alterations in Shh expression.
Volume: 177
Issue: 1
Pages: 139-45
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Publication
34822715 | J:316178
 
First Author: Gamart J
Year: 2021
Journal: Development
Title: SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.
Volume: 148
Issue: 23
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Publication
19422820 | J:150759
First Author: Lallemand Y
Year: 2009
Journal: Dev Biol
Title: Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb.
Volume: 331
Issue: 2
Pages: 189-98
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Publication
28490013 | J:252662
First Author: Jiang W
Year: 2017
Journal: Dev Neurosci
Title: Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1.
Volume: 39
Issue: 5
Pages: 361-374
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Publication
7628698 | J:27442
First Author: Masuya H
Year: 1995
Journal: Genes Dev
Title: A duplicated zone of polarizing activity in polydactylous mouse mutants.
Volume: 9
Issue: 13
Pages: 1645-53
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GXD Expression
GXD Expression
 
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1998-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:1289471
Age: embryonic day 7.5
Note: Shh is expressed in the axial mesoderm in wild-type embryos.
Specimen Label: not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1310045
Assay Type: RNA in situ
Annotation Date: 1998-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1310055
Age: embryonic day 11.5
Note: Shh was detected only in the posterior mesenchyme.
Specimen Label: not shown
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331006
Age: embryonic day 11.5
Image: 2A
Note: Shh is expressed in the distal posterior limb margin.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-07-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1735620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1340495
Age: embryonic day 12.0
Image: 1V
Note: Shh is expressed at the tip of the tooth epithelium.
Specimen Label: 1V
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1998-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607111
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:1289471
Age: embryonic day 7.5
Note: Shh is expressed in the axial mesoderm in wild-type embryos.
Specimen Label: not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1310045
Assay Type: RNA in situ
Annotation Date: 1998-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1310055
Age: embryonic day 10.5
Image: 2A
Note: Shh was detected in a posterior mesenchymal domain.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1310045
Assay Type: RNA in situ
Annotation Date: 1998-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1310055
Age: embryonic day 10.5
Image: 2B
Note: Shh was detected in a posterior mesenchymal domain.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1310045
Assay Type: RNA in situ
Annotation Date: 1998-11-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1310055
Age: embryonic day 10.5
Image: 2C
Note: Shh was detected in a posterior mesenchymal domain.
Specimen Label: 2C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331006
Age: embryonic day 11.5
Image: 2A
Note: Shh is expressed in the distal posterior limb margin.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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Publication
11180951 | J:67731
First Author: Revest JM
Year: 2001
Journal: Dev Biol
Title: Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4.
Volume: 231
Issue: 1
Pages: 47-62
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Publication
11091071 | J:66280
First Author: Zhao X
Year: 2000
Journal: Mech Dev
Title: Transgenically ectopic expression of Bmp4 to the Msx1 mutant dental mesenchyme restores downstream gene expression but represses Shh and Bmp2 in the enamel knot of wild type tooth germ.
Volume: 99
Issue: 1-2
Pages: 29-38
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Publication
7334311 | J:31035
 
First Author: Knudsen TB
Year: 1981
Journal: J Embryol Exp Morphol
Title: The role of morphogenetic cell death during abnormal limb-bud outgrowth in mice heterozygous for the dominant mutation Hemimelia-extra toe (Hmx).
Volume: 65 Suppl
Pages: 289-307
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Publication
7588050 | J:29274
First Author: Chan DC
Year: 1995
Journal: Development
Title: Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud.
Volume: 121
Issue: 10
Pages: 3151-62
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Publication
- | J:13518
 
First Author: Southard JL
Year: 1971
Journal: Mouse News Lett
Title: Soft coat and hemimelic extra toes.
Volume: 45
Pages: 29
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Publication
8835524 | J:31800
First Author: Rusiniak ME
Year: 1996
Journal: Mamm Genome
Title: Molecular markers near the mouse brachymorphic (bm) gene, which affects connective tissues and bleeding time.
Volume: 7
Issue: 2
Pages: 98-102
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Publication
9915577 | J:51920
First Author: Caubit X
Year: 1999
Journal: Dev Dyn
Title: Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud.
Volume: 214
Issue: 1
Pages: 66-80
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Publication
2307472 | J:10340
First Author: Martin GR
Year: 1990
Journal: Genomics
Title: Mapping of the two mouse engrailed-like genes: close linkage of En-1 to dominant hemimelia (Dh) on chromosome 1 and of En-2 to hemimelic extra-toes (Hx) on chromosome 5.
Volume: 6
Issue: 2
Pages: 302-8
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Publication
31719045 | J:284130
 
First Author: Okuhara S
Year: 2019
Journal: Development
Title: Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature.
Volume: 146
Issue: 21
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Publication
32581832 | J:295947
 
First Author: Ohki S
Year: 2020
Journal: Front Physiol
Title: Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development.
Volume: 11
Pages: 532
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
31511252 | J:284117
 
First Author: Williamson I
Year: 2019
Journal: Development
Title: Developmentally regulated Shh expression is robust to TAD perturbations.
Volume: 146
Issue: 19
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GXD Expression
GXD Expression
Probe: MGI:1332583
Assay Type: RNA in situ
Annotation Date: 1999-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:1332609
Age: embryonic day 8.5
Image: 4B
Note: In the anterior part, Shh is co-expressed in the floor plate with HNF3b.
Specimen Label: 4B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7339132
Assay Type: RNA in situ
Annotation Date: 2022-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2757717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7339178
Age: embryonic day 10.5
Note: Shh expression was not affected in cloacal epithelium of the conditional knockout mice.
Specimen Label: 4D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1345546
Age: embryonic day 11.5
Image: 6D & 6F
Note: Shh expression has split in two, leaving a gap devoid of expression.
Specimen Label: 6D & 6F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2152778
Assay Type: RNA in situ
Annotation Date: 2001-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624715
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:2152857
Age: embryonic day 9.5
Image: 1E
Note: Authors state that Shh expression is shown as a known marker for the gut epithelium.
Specimen Label: 1E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 2018-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6202039
Age: embryonic day 10.5
Image: 6A
Note: Expression of Shh was detected in the ventral midline. There was colocalization with Foxa2 immunostaining.
Specimen Label: 6A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7703736
Assay Type: RNA in situ
Annotation Date: 2024-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7703742
Age: embryonic day 10.5
Note: Close association of Shh and Hhip expression maintained in caudal region at tail bud stages.
Specimen Label: 3c
Detected: true
Specimen Num: 2
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Publication
14764698 | J:88047
First Author: Shah DK
Year: 2004
Journal: J Immunol
Title: Reduced thymocyte development in sonic hedgehog knockout embryos.
Volume: 172
Issue: 4
Pages: 2296-306
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Gene
305002 | Sdccag8
Type: gene
Organism: rat
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Gene
490374 | SDCCAG8
Type: gene
Organism: dog, domestic
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Gene
469732 | SDCCAG8
Type: gene
Organism: chimpanzee
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Gene
616342 | SDCCAG8
Type: gene
Organism: cattle
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Gene
556980 | sdccag8
Type: gene
Organism: zebrafish
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Gene
705545 | SDCCAG8
Type: gene
Organism: macaque, rhesus
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Publication
19394325 | J:150375
First Author: Cobourne MT
Year: 2009
Journal: Dev Biol
Title: Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome.
Volume: 331
Issue: 1
Pages: 38-49
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Publication
22340503 | J:181469
First Author: Lettice LA
Year: 2012
Journal: Dev Cell
Title: Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.
Volume: 22
Issue: 2
Pages: 459-67
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Publication
15108308 | J:89978
First Author: Powles N
Year: 2004
Journal: Dev Dyn
Title: Regulatory analysis of the mouse Fgf3 gene: control of embryonic expression patterns and dependence upon sonic hedgehog (Shh) signalling.
Volume: 230
Issue: 1
Pages: 44-56
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GXD Expression
GXD Expression
Probe: MGI:2684133
Assay Type: Immunohistochemistry
Annotation Date: 2019-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6343549
Age: embryonic day 12.5
Image: S1 E12.5
Note: Compared to an adjacent section, there is a gap between Shh and Gli2 expression in the ventral midbrain.
Specimen Label: S1 E12.5
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1331350
Age: embryonic day 9.5
Image: 6C
Note: Shh is not detected at more caudal levels of the midgut in mutants, although it is present elsewhere.
Specimen Label: 6C
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331006
Age: embryonic day 11.5
Image: 2B
Note: Shh is expressed in the distal posterior limb margin. No expression was detected outside the endogenous ZPA.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1327343
Age: embryonic day 10.5
Image: 10.5 p.c. ebmryo
Note: Shh expression is shown in a region of posterior mesenchyme corresponding to the zone of polarizing activity.
Specimen Label: 10.5 p.c. ebmryo
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1194645
Assay Type: RNA in situ
Annotation Date: 1998-07-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286019
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1275014
Age: embryonic day 11.5
Image: 1A
Note: Shh is expressed at low level throughout the epithelium and at a high level in the distal buds.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:23359
Assay Type: RNA in situ
Annotation Date: 1999-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331006
Age: embryonic day 11.5
Image: 2B
Note: Shh is expressed in the distal posterior limb margin. No expression was detected outside the endogenous ZPA.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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Publication
12595239 | J:82193
First Author: Murdoch JN
Year: 2003
Journal: Mol Cell Neurosci
Title: Genomic organization and embryonic expression of Igsf8, an immunoglobulin superfamily member implicated in development of the nervous system and organ epithelia.
Volume: 22
Issue: 1
Pages: 62-74
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Publication
10603087 | J:59199
First Author: Pabst O
Year: 2000
Journal: Dev Genes Evol
Title: NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos.
Volume: 210
Issue: 1
Pages: 47-50
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Publication
9731532 | J:49604
First Author: Litingtung Y
Year: 1998
Journal: Nat Genet
Title: Sonic hedgehog is essential to foregut development.
Volume: 20
Issue: 1
Pages: 58-61
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Publication
12167401 | J:78334
First Author: Liu W
Year: 2002
Journal: Dev Biol
Title: Sonic hedgehog regulates otic capsule chondrogenesis and inner ear development in the mouse embryo.
Volume: 248
Issue: 2
Pages: 240-50
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Publication
8837770 | J:35802
First Author: Chiang C
Year: 1996
Journal: Nature
Title: Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
Volume: 383
Issue: 6599
Pages: 407-13
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Publication
11520664 | J:71419
First Author: Reddy S
Year: 2001
Journal: Mech Dev
Title: Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.
Volume: 107
Issue: 1-2
Pages: 69-82
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Publication
25695606 | J:279222
 
First Author: Pan YB
Year: 2015
Journal: Cell Death Dis
Title: Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth.
Volume: 6
Pages: e1653
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Publication
16543359 | J:108214
First Author: Williamson KA
Year: 2006
Journal: Hum Mol Genet
Title: Mutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome.
Volume: 15
Issue: 9
Pages: 1413-22
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Publication
14499653 | J:85580
First Author: Fedtsova N
Year: 2003
Journal: Dev Biol
Title: Sonic hedgehog regulates the position of the trigeminal ganglia.
Volume: 261
Issue: 2
Pages: 456-69
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Publication
15111333 | J:89589
First Author: Fagman H
Year: 2004
Journal: Am J Pathol
Title: Genetic deletion of sonic hedgehog causes hemiagenesis and ectopic development of the thyroid in mouse.
Volume: 164
Issue: 5
Pages: 1865-72
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Publication
16299054 | J:105309
First Author: van Tuyl M
Year: 2006
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Iroquois genes influence proximo-distal morphogenesis during rat lung development.
Volume: 290
Issue: 4
Pages: L777-L789
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Publication
11748155 | J:73075
First Author: Dahmane N
Year: 2001
Journal: Development
Title: The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.
Volume: 128
Issue: 24
Pages: 5201-12
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Publication
12074550 | J:77812
First Author: Perriton CL
Year: 2002
Journal: Dev Biol
Title: Sonic hedgehog signaling from the urethral epithelium controls external genital development.
Volume: 247
Issue: 1
Pages: 26-46
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Publication
15680353 | J:104611
First Author: Moore-Scott BA
Year: 2005
Journal: Dev Biol
Title: Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs.
Volume: 278
Issue: 2
Pages: 323-35
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Publication
9882493 | J:52207
First Author: Chiang C
Year: 1999
Journal: Dev Biol
Title: Essential role for Sonic hedgehog during hair follicle morphogenesis.
Volume: 205
Issue: 1
Pages: 1-9
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Publication
32848868 | J:313941
 
First Author: Zhang S
Year: 2020
Journal: Front Physiol
Title: Action of Actomyosin Contraction With Shh Modulation Drive Epithelial Folding in the Circumvallate Papilla.
Volume: 11
Pages: 936
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Publication
16492970 | J:106091
First Author: Yamagishi C
Year: 2006
Journal: Pediatr Res
Title: Sonic hedgehog is essential for first pharyngeal arch development.
Volume: 59
Issue: 3
Pages: 349-54
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Publication
11118883 | J:66531
First Author: Kraus P
Year: 2001
Journal: Mech Dev
Title: Some distal limb structures develop in mice lacking Sonic hedgehog signaling.
Volume: 100
Issue: 1
Pages: 45-58
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Publication
11412027 | J:70279
First Author: Garg V
Year: 2001
Journal: Dev Biol
Title: Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development.
Volume: 235
Issue: 1
Pages: 62-73
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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