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Search results 301 to 330 out of 330 for Sirt2

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Type Details Score
Publication
First Author: Pandithage R
Year: 2008
Journal: J Cell Biol
Title: The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility.
Volume: 180
Issue: 5
Pages: 915-29
Publication
First Author: Park SH
Year: 2012
Journal: Transl Cancer Res
Title: SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis.
Volume: 1
Issue: 1
Pages: 15-21
Allele
Name: transgene insertion GK6, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: mutant stock, transgenic
Protein
Organism: Mus musculus/domesticus
Length: 785  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 47  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 758  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
Publication
First Author: Zou L
Year: 2003
Journal: Science
Title: Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.
Volume: 300
Issue: 5625
Pages: 1542-8
Protein Domain
Type: Family
Description: The function of the ATR-ATRIP (ATR-interacting protein) protein kinase complex is crucial for the cellular response to replication stress and DNA damage. ATRIP is a regulatory partner of ATR. The binding of ATRIP to replication protein A-coated ssDNA at sites of DNA damage drives ATR activation and enables the ATR-ATRIP complex to stimulate phosphorylation of substrates, such as Rad17 or Chk1, and the initiation of checkpoint signalling []. ATRIP deacetylation by SIRT2 promotes ATR-ATRIP bindingto RPA-ssDNA [].
Publication    
First Author: Bhaskar A
Year: 2020
Journal: Elife
Title: Host sirtuin 2 as an immunotherapeutic target against tuberculosis.
Volume: 9
Publication
First Author: Chen X
Year: 2015
Journal: PLoS One
Title: The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia.
Volume: 10
Issue: 1
Pages: e0116919
Publication
First Author: Roy S
Year: 2024
Journal: Commun Biol
Title: Dab2 (Disabled-2), an adaptor protein, regulates self-renewal of hair follicle stem cells.
Volume: 7
Issue: 1
Pages: 525
Publication
First Author: Jing H
Year: 2016
Journal: Cancer Cell
Title: A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity.
Volume: 29
Issue: 3
Pages: 297-310
Publication
First Author: Sun L
Year: 2022
Journal: Sci Adv
Title: Deacetylation of ATG4B promotes autophagy initiation under starvation.
Volume: 8
Issue: 31
Pages: eabo0412
Publication
First Author: Suzuki K
Year: 2007
Journal: Neuroscience
Title: Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: a crucial role of tubulin deacetylation.
Volume: 147
Issue: 3
Pages: 599-612
Publication
First Author: Guo L
Year: 2019
Journal: J Biol Chem
Title: Enhanced acetylation of ATP-citrate lyase promotes the progression of nonalcoholic fatty liver disease.
Volume: 294
Issue: 31
Pages: 11805-11816
Publication
First Author: Guo Q
Year: 2019
Journal: Am J Transl Res
Title: Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation-induced oral mucositis in mice.
Volume: 11
Issue: 8
Pages: 4789-4799
Publication  
First Author: Sun W
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: MYO1F regulates antifungal immunity by regulating acetylation of microtubules.
Volume: 118
Issue: 30
Publication
First Author: Binker MG
Year: 2015
Journal: Biochem Biophys Res Commun
Title: ER stress-associated CTRC mutants decrease stimulated pancreatic zymogen secretion through SIRT2-mediated microtubule dysregulation.
Volume: 463
Issue: 3
Pages: 329-35
Publication
First Author: Gaur U
Year: 2017
Journal: PLoS One
Title: Molecular evolutionary patterns of NAD+/Sirtuin aging signaling pathway across taxa.
Volume: 12
Issue: 8
Pages: e0182306
Publication
First Author: Fonseca Costa SS
Year: 2017
Journal: PLoS One
Title: Normalisation against Circadian and Age-Related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice.
Volume: 12
Issue: 1
Pages: e0169615
Publication  
First Author: Roy Chowdhury S
Year: 2018
Journal: Mol Cell Neurosci
Title: Depressed mitochondrial function and electron transport Complex II-mediated H2O2 production in the cortex of type 1 diabetic rodents.
Volume: 90
Pages: 49-59
Publication
First Author: Yu J
Year: 2016
Journal: J Neurochem
Title: High glucose-induced oxidative stress represses sirtuin deacetylase expression and increases histone acetylation leading to neural tube defects.
Volume: 137
Issue: 3
Pages: 371-83
Publication
First Author: Yang Q
Year: 2018
Journal: Reproduction
Title: Melatonin attenuates postovulatory oocyte dysfunction by regulating SIRT1 expression.
Volume: 156
Issue: 1
Pages: 81-92
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data