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Search results 301 to 400 out of 556 for Socs3

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Type Details Score
Publication
16906166 | J:112649
First Author: Stumhofer JS
Year: 2006
Journal: Nat Immunol
Title: Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.
Volume: 7
Issue: 9
Pages: 937-45
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27213690 | J:259141
First Author: Delconte RB
Year: 2016
Journal: Nat Immunol
Title: CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Volume: 17
Issue: 7
Pages: 816-24
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Publication
25015957 | J:220139
First Author: Cao AT
Year: 2014
Journal: J Leukoc Biol
Title: TLR4 regulates IFN-γ and IL-17 production by both thymic and induced Foxp3+ Tregs during intestinal inflammation.
Volume: 96
Issue: 5
Pages: 895-905
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Publication
20870174 | J:164648
First Author: Xu L
Year: 2010
Journal: Immunity
Title: Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I.
Volume: 33
Issue: 3
Pages: 313-25
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Publication
16888100 | J:133477
First Author: Panopoulos AD
Year: 2006
Journal: Blood
Title: STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils.
Volume: 108
Issue: 12
Pages: 3682-90
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Publication
20716764 | J:259498
First Author: Qualls JE
Year: 2010
Journal: Sci Signal
Title: Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling.
Volume: 3
Issue: 135
Pages: ra62
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Publication
33770504 | J:306939
First Author: Yasuda M
Year: 2021
Journal: Neuron
Title: An activity-dependent determinant of synapse elimination in the mammalian brain.
Volume: 109
Issue: 8
Pages: 1333-1349.e6
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Publication
25937169 | J:255119
First Author: Belin S
Year: 2015
Journal: Neuron
Title: Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomics.
Volume: 86
Issue: 4
Pages: 1000-1014
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Publication
35767994 | J:329556
First Author: Jacobi A
Year: 2022
Journal: Neuron
Title: Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells.
Volume: 110
Issue: 16
Pages: 2625-2645.e7
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Publication
17452461 | J:122731
First Author: Fukuda S
Year: 2007
Journal: Mol Cell Biol
Title: Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells.
Volume: 27
Issue: 13
Pages: 4931-7
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Publication
9344848 | J:43683
First Author: Masuhara M
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Cloning and characterization of novel CIS family genes.
Volume: 239
Issue: 2
Pages: 439-46
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9844915 | J:52177
First Author: Yoshimura A
Year: 1998
Journal: Leukemia
Title: The CIS/JAB family: novel negative regulators of JAK signaling pathways.
Volume: 12
Issue: 12
Pages: 1851-7
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18713987 | J:138956
First Author: Qin H
Year: 2008
Journal: J Immunol
Title: Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes.
Volume: 181
Issue: 5
Pages: 3167-76
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Publication
19038858 | J:146080
First Author: Schulz LC
Year: 2009
Journal: Biol Reprod
Title: Effect of leptin on mouse trophoblast giant cells.
Volume: 80
Issue: 3
Pages: 415-24
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17947670 | J:153002
First Author: Qin H
Year: 2007
Journal: J Immunol
Title: Molecular mechanism of lipopolysaccharide-induced SOCS-3 gene expression in macrophages and microglia.
Volume: 179
Issue: 9
Pages: 5966-76
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Publication
26598325 | J:228008
 
First Author: Jin D
Year: 2015
Journal: Nat Commun
Title: Restoration of skilled locomotion by sprouting corticospinal axons induced by co-deletion of PTEN and SOCS3.
Volume: 6
Pages: 8074
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9889194 | J:52380
First Author: Nicholson SE
Year: 1999
Journal: EMBO J
Title: Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.
Volume: 18
Issue: 2
Pages: 375-85
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10867663 | J:62883
First Author: Polizzotto MN
Year: 2000
Journal: J Comp Neurol
Title: Expression of "suppressor of cytokine signalling" (SOCS) genes in the developing and adult mouse nervous system.
Volume: 423
Issue: 2
Pages: 348-58
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18025162 | J:133009
First Author: El Kasmi KC
Year: 2007
Journal: J Immunol
Title: Cutting edge: A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway.
Volume: 179
Issue: 11
Pages: 7215-9
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9419338 | J:51029
First Author: Hilton DJ
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Twenty proteins containing a C-terminal SOCS box form five structural classes.
Volume: 95
Issue: 1
Pages: 114-9
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34103328 | J:314445
First Author: Tirado-Gonzalez I
Year: 2021
Journal: Cancer Discov
Title: AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia.
Volume: 11
Issue: 11
Pages: 2924-2943
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26795246 | J:263563
First Author: Delconte RB
Year: 2016
Journal: Immunity
Title: The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.
Volume: 44
Issue: 1
Pages: 103-115
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12438448 | J:80183
First Author: Hong F
Year: 2002
Journal: J Clin Invest
Title: Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS.
Volume: 110
Issue: 10
Pages: 1503-13
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Publication
25136113 | J:214820
First Author: Tadokoro T
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells.
Volume: 111
Issue: 35
Pages: E3641-9
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17581589 | J:123351
First Author: Nurieva R
Year: 2007
Journal: Nature
Title: Essential autocrine regulation by IL-21 in the generation of inflammatory T cells.
Volume: 448
Issue: 7152
Pages: 480-3
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29808009 | J:336458
First Author: Ruess DA
Year: 2018
Journal: Nat Med
Title: Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Volume: 24
Issue: 7
Pages: 954-960
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23426178 | J:196394
First Author: Zhang H
Year: 2013
Journal: J Clin Invest
Title: IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality.
Volume: 123
Issue: 3
Pages: 1019-31
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Publication
28642362 | J:246100
First Author: Renault-Mihara F
Year: 2017
Journal: J Cell Biol
Title: Regulation of RhoA by STAT3 coordinates glial scar formation.
Volume: 216
Issue: 8
Pages: 2533-2550
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Publication
28408410 | J:242006
First Author: Fujita Y
Year: 2017
Journal: J Exp Med
Title: Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior.
Volume: 214
Issue: 5
Pages: 1431-1452
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39353435 | J:358124
     
First Author: Delpech C
Year: 2024
Journal: Dev Cell
Title: Axon guidance during mouse central nervous system regeneration is required for specific brain innervation.
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38754428 | J:349169
     
First Author: Dellorusso PV
Year: 2024
Journal: Cell Stem Cell
Title: Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells.
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Publication
24129709 | J:206059
 
First Author: Qin S
Year: 2013
Journal: Nat Commun
Title: Cross-talk between KLF4 and STAT3 regulates axon regeneration.
Volume: 4
Pages: 2633
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Publication
20530874 | J:163717
First Author: De Domenico I
Year: 2010
Journal: J Clin Invest
Title: Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice.
Volume: 120
Issue: 7
Pages: 2395-405
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Publication
27974197 | J:241713
First Author: Rauch KS
Year: 2016
Journal: Cell Rep
Title: Id3 Maintains Foxp3 Expression in Regulatory T Cells by Controlling a Transcriptional Network of E47, Spi-B, and SOCS3.
Volume: 17
Issue: 11
Pages: 2827-2836
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Publication
16185683 | J:103443
First Author: Wilhelm D
Year: 2005
Journal: Dev Biol
Title: Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination.
Volume: 287
Issue: 1
Pages: 111-24
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Publication
15677447 | J:98567
First Author: Novotny-Diermayr V
Year: 2005
Journal: J Biol Chem
Title: Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
Volume: 280
Issue: 13
Pages: 12747-57
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35344606 | J:360573
First Author: Zhou Y
Year: 2023
Journal: Hepatology
Title: Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7-acetylated and cytoplasm-translocated G protein GαS.
Volume: 77
Issue: 4
Pages: 1106-1121
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9032278 | J:44165
First Author: Fu X
Year: 1997
Journal: Mol Cell Biol
Title: E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts.
Volume: 17
Issue: 3
Pages: 1503-12
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Publication
15169905 | J:91027
First Author: Ueki K
Year: 2004
Journal: Mol Cell Biol
Title: Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms.
Volume: 24
Issue: 12
Pages: 5434-46
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Publication
15601820 | J:94679
First Author: Kamura T
Year: 2004
Journal: Genes Dev
Title: VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
Volume: 18
Issue: 24
Pages: 3055-65
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17114459 | J:140695
First Author: El Kasmi KC
Year: 2006
Journal: J Immunol
Title: General nature of the STAT3-activated anti-inflammatory response.
Volume: 177
Issue: 11
Pages: 7880-8
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10374907 | J:55343
First Author: Aringer M
Year: 1999
Journal: Life Sci
Title: Janus kinases and their role in growth and disease.
Volume: 64
Issue: 24
Pages: 2173-86
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36370710 | J:333386
First Author: Wang X
Year: 2023
Journal: Neuron
Title: Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis.
Volume: 111
Issue: 2
Pages: 236-255.e7
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Publication
27721430 | J:259382
First Author: Torre S
Year: 2017
Journal: Nat Immunol
Title: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.
Volume: 18
Issue: 1
Pages: 54-63
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27748374 | J:241037
First Author: Clarke M
Year: 2017
Journal: Leukemia
Title: Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3.
Volume: 31
Issue: 4
Pages: 957-966
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Publication
18083102 | J:131447
First Author: Rothlin CV
Year: 2007
Journal: Cell
Title: TAM receptors are pleiotropic inhibitors of the innate immune response.
Volume: 131
Issue: 6
Pages: 1124-36
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21514445 | J:171578
First Author: Chen W
Year: 2011
Journal: Am J Pathol
Title: Protein phosphatase 2A catalytic subunit α (PP2Acα) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway.
Volume: 178
Issue: 5
Pages: 2333-43
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Publication
27626668 | J:238993
First Author: Kaneko K
Year: 2016
Journal: Cell Rep
Title: Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions.
Volume: 16
Issue: 11
Pages: 3003-3015
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17965409 | J:128959
First Author: Wang H
Year: 2007
Journal: J Biol Chem
Title: Stage-specific integration of maternal and embryonic peroxisome proliferator-activated receptor delta signaling is critical to pregnancy success.
Volume: 282
Issue: 52
Pages: 37770-82
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18635606 | J:139252
First Author: Lokmane L
Year: 2008
Journal: Development
Title: Crucial role of vHNF1 in vertebrate hepatic specification.
Volume: 135
Issue: 16
Pages: 2777-86
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29361558 | J:257927
 
First Author: Fairchild CL
Year: 2018
Journal: Development
Title: RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion.
Volume: 145
Issue: 3
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24210661 | J:205551
First Author: Simó S
Year: 2013
Journal: Dev Cell
Title: Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors.
Volume: 27
Issue: 4
Pages: 399-411
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19228596 | J:152946
First Author: Sferruzzi-Perri AN
Year: 2009
Journal: Biol Reprod
Title: Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.
Volume: 81
Issue: 1
Pages: 207-21
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32150249 | J:286621
First Author: Iwagawa T
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: Cd9 Protects Photoreceptors from Injury and Potentiates Edn2 Expression.
Volume: 61
Issue: 3
Pages: 7
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27306493 | J:253786
 
First Author: Hu X
Year: 2016
Journal: Sci Rep
Title: Phosphoinositide 3-Kinase (PI3K) Subunit p110δ Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse.
Volume: 6
Pages: 28201
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27318131 | J:239041
 
First Author: Norden DM
Year: 2016
Journal: Neurobiol Aging
Title: Insensitivity of astrocytes to interleukin 10 signaling following peripheral immune challenge results in prolonged microglial activation in the aged brain.
Volume: 44
Pages: 22-41
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29438518 | J:258670
First Author: Mahany EB
Year: 2018
Journal: Endocrinology
Title: Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome.
Volume: 159
Issue: 4
Pages: 1718-1733
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21308778 | J:233117
First Author: Saeed H
Year: 2011
Journal: J Bone Miner Res
Title: Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Volume: 26
Issue: 7
Pages: 1494-505
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15163632 | J:225638
First Author: Yoshida S
Year: 2004
Journal: Hum Mol Genet
Title: Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl.
Volume: 13
Issue: 14
Pages: 1487-503
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35729116 | J:326354
First Author: Allègre N
Year: 2022
Journal: Nat Commun
Title: NANOG initiates epiblast fate through the coordination of pluripotency genes expression.
Volume: 13
Issue: 1
Pages: 3550
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24859004 | J:219394
First Author: Boroviak T
Year: 2014
Journal: Nat Cell Biol
Title: The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.
Volume: 16
Issue: 6
Pages: 516-28
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20439489 | J:163558
First Author: Tarantino C
Year: 2010
Journal: FASEB J
Title: miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells.
Volume: 24
Issue: 9
Pages: 3255-63
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27480124 | J:237787
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
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- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Tg(Lck-Socs3)1Kubo | MGI:3783708
Name: transgene insertion 1, Masato Kubo
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
32030817 | J:303783
First Author: Draijer C
Year: 2020
Journal: FASEB J
Title: Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation.
Volume: 34
Issue: 3
Pages: 4718-4731
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Publication
38928564 | J:357781
 
First Author: Lin CY
Year: 2024
Journal: Brain Sci
Title: The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice.
Volume: 14
Issue: 6
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Publication
22114683 | J:180957
First Author: Aziz M
Year: 2011
Journal: PLoS One
Title: Pre-treatment of recombinant mouse MFG-E8 downregulates LPS-induced TNF-α production in macrophages via STAT3-mediated SOCS3 activation.
Volume: 6
Issue: 11
Pages: e27685
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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