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Search results 301 to 400 out of 6537 for Sox2

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Type Details Score
Publication
29732603 | J:266183
First Author: Cerrato V
Year: 2018
Journal: Glia
Title: Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia.
Volume: 66
Issue: 9
Pages: 1929-1946
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Publication
21185279 | J:278249
First Author: Iwafuchi-Doi M
Year: 2011
Journal: Dev Biol
Title: The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.
Volume: 352
Issue: 2
Pages: 354-66
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Publication
18719084 | J:146694
First Author: Lin YP
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Sox2 plays a role in the induction of amacrine and Müller glial cells in mouse retinal progenitor cells.
Volume: 50
Issue: 1
Pages: 68-74
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Publication
22334693 | J:315243
First Author: Gao Z
Year: 2012
Journal: J Biol Chem
Title: Determination of protein interactome of transcription factor Sox2 in embryonic stem cells engineered for inducible expression of four reprogramming factors.
Volume: 287
Issue: 14
Pages: 11384-97
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GXD Expression
GXD Expression
 
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599920
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6E'
Note: Sox2 was not detected in adrenal.
Specimen Label: S6E'
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599920
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6K'
Note: Sox2 was not detected in adrenal.
Specimen Label: S6K'
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6274524
Age: embryonic day 16.5
Image: 2B inset
Note: Authors report co-expression with endogenous Sox2 protein.
Specimen Label: 2B inset
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6274516
Assay Type: Immunohistochemistry
Annotation Date: 2019-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6274527
Age: embryonic day 16.5
Image: 2B inset
Note: Authors report co-expression with Sox2 GFP reporter.
Specimen Label: 2B inset
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6184037
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191366
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Sox2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6184037
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191366
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Sox2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6184037
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191366
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Sox2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6184037
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191366
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Sox2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6184037
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191366
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Sox2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6184037
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191366
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Sox2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6184037
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191366
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Sox2
Detected: true
Specimen Num: 7
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Publication
15456859 | J:145841
First Author: Tanaka S
Year: 2004
Journal: Mol Cell Biol
Title: Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells.
Volume: 24
Issue: 20
Pages: 8834-46
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Publication
15695336 | J:96641
First Author: Le N
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination.
Volume: 102
Issue: 7
Pages: 2596-601
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Publication
38408234 | J:353363
First Author: Gao J
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: CHD7 and SOX2 act in a common gene regulatory network during mammalian semicircular canal and cochlear development.
Volume: 121
Issue: 10
Pages: e2311720121
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Strain
MGI:5700030 | STOCK Sox2<tm3Skn>/Cnrm
Attribute String: targeted mutation, mutant stock
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Publication
16166252 | J:187950
First Author: Western P
Year: 2005
Journal: Stem Cells
Title: Analysis of Esg1 expression in pluripotent cells and the germline reveals similarities with Oct4 and Sox2 and differences between human pluripotent cell lines.
Volume: 23
Issue: 10
Pages: 1436-42
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Publication
36353976 | J:352915
First Author: Liu Y
Year: 2023
Journal: Glia
Title: Specific knockout of Sox2 in astrocytes reduces reactive astrocyte formation and promotes recovery after early postnatal traumatic brain injury in mouse cortex.
Volume: 71
Issue: 3
Pages: 602-615
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Publication
31988094 | J:285618
 
First Author: Teramoto M
Year: 2020
Journal: Biol Open
Title: The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components.
Volume: 9
Issue: 2
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Publication
24107947 | J:202668
First Author: Pan W
Year: 2013
Journal: J Neurosci
Title: Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear.
Volume: 33
Issue: 41
Pages: 16146-57
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Publication
24746758 | J:317856
First Author: Dogan I
Year: 2014
Journal: Lung Cancer
Title: SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.
Volume: 85
Issue: 1
Pages: 1-6
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Publication
27300003 | J:238291
First Author: Mohanty V
Year: 2016
Journal: Stem Cells
Title: Folate Receptor Alpha Upregulates Oct4, Sox2 and Klf4 and Downregulates miR-138 and miR-let-7 in Cranial Neural Crest Cells.
Volume: 34
Issue: 11
Pages: 2721-2732
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Publication
10804179 | J:62026
First Author: Zappone MV
Year: 2000
Journal: Development
Title: Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells.
Volume: 127
Issue: 11
Pages: 2367-82
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Publication
34099510 | J:320455
     
First Author: Stone JS
Year: 2021
Journal: J Neurosci
Title: The transcription factor Sox2 is required to maintain the cell type-specific properties and innervation of type II vestibular hair cells in adult mice.
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Publication
22354878 | J:181633
First Author: Liu Z
Year: 2012
Journal: Dev Dyn
Title: In vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.
Volume: 241
Issue: 4
Pages: 684-96
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Publication
21076177 | J:170271
First Author: Johansson H
Year: 2010
Journal: Aging (Albany NY)
Title: Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination.
Volume: 2
Issue: 11
Pages: 815-22
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Publication
22513373 | J:184001
First Author: Ahmed M
Year: 2012
Journal: Development
Title: EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear.
Volume: 139
Issue: 11
Pages: 1965-77
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HT Experiment
GSE41597 | Sox2 ablation in the DP alters its gene expression signature
Series Id: E-GEOD-41597
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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GXD Expression
GXD Expression
 
Probe: MGI:5502435
Assay Type: Immunohistochemistry
Annotation Date: 2013-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5502448
Age: embryonic day 14.5
Note: Sox2 co-expresses with survivin in the subventricular zone.
Specimen Label: 7A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5762877
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6763035
Age: embryonic day 12.5
Image: 10E
Note: Jag1 and Sox2 exhibited largely overlapping expression domains.
Specimen Label: 10E
Detected: true
Specimen Num: 7
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Publication
33593819 | J:303700
 
First Author: Cajigas I
Year: 2021
Journal: Development
Title: Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain.
Volume: 148
Issue: 6
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Protein
Q60I23
Organism: Mus musculus/domesticus
Length: 319  
Fragment?: false
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ncRNA Gene
MGI:2444112 | Sox2ot
Type: lncRNA_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:5430034
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7444491
Age: embryonic day 9.5
Image: 4B Tbx6
Note: Co-expression of YFP with Sox2 was 28% in the heterozygote chordo-neural hinge.
Specimen Label: 4B Tbx6
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5430034
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7444491
Age: embryonic day 9.5
Image: 4B Tbx6
Note: A 74% overlap of YFP with Sox2 expression was detected in the mutant chordo-neural hinge.
Specimen Label: 4B Tbx6
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6J'
Note: Sox2 was found expressed in the retina similar to, but at much lower levels than Zscan10.
Specimen Label: S6J'
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6P'
Note: Sox2 was found expressed in the retina similar to, but at much lower levels than Zscan10.
Specimen Label: S6P'
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:7785105
Assay Type: Immunohistochemistry
Annotation Date: 2024-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7785107
Age: embryonic day 12.5
Note: At 12.5 dpc Foxd3 and Sox2 are co-expressed in the dorsal root ganglion.
Specimen Label: 1F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6F'
Note: Sox2 was found expressed in the heart similar to, but at much lower levels than Zscan10.
Specimen Label: S6F'
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6L'
Note: Sox2 was found expressed in the heart similar to, but at much lower levels than Zscan10.
Specimen Label: S6L'
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7447366
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-25
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3670424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7447377
Age: embryonic day 16.5
Note: Sox2 was successfully deleted, with only a small number of Sox2-positive cells detectable.
Specimen Label: not shown
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
Probe: MGI:6681896
Assay Type: RNA in situ
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6682144
Age: embryonic day 10.5
Image: S2A(b) N2-/-
Note: Sox2 expression at E10.5 is indistinguishable between wild type and N2-/- embryos.
Specimen Label: S2A(b) N2-/-
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
Probe: MGI:6681896
Assay Type: RNA in situ
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:6682144
Age: embryonic day 7.75
Image: 1Ca N2-/- E7.75
Note: Sox2 expression in the posterior half of the embryos initiated in the N2-/- embryo.
Specimen Label: 1Ca N2-/- E7.75
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:6681896
Assay Type: RNA in situ
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160429
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:6682144
Age: embryonic day 6.75
Image: 1Ca N2-/- E6.75
Note: Sox2 expression in the periphery of the chorion was unaffected in the N2-/- homozygous embryo.
Specimen Label: 1Ca N2-/- E6.75
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6274516
Assay Type: Immunohistochemistry
Annotation Date: 2019-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6274527
Age: embryonic day 16.5
Image: 1H
Note: Authors report Tubb3-expressing cells co-expressing Sox2 found intermittently in the ventricular zone and subventricular zone.
Specimen Label: 1H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6681896
Assay Type: RNA in situ
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611211
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:6682144
Age: embryonic day 7.5
Image: 1Ca N2-/- E7.5
Note: Sox2 expression in the periphery of the chorion was unaffected in the N2-/- homozygous embryo.
Specimen Label: 1Ca N2-/- E7.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6681896
Assay Type: RNA in situ
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611211
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:6682144
Age: embryonic day 7.75
Image: 1Ca N2-/- E7.75
Note: Sox2 expression in the periphery of the chorion was unaffected in the N2-/- homozygous embryo.
Specimen Label: 1Ca N2-/- E7.75
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:7447366
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-25
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3277924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7447377
Age: embryonic day 16.5
Note: Sox2 was successfully deleted, with only a small number of Sox2-positive cells detectable.
Specimen Label: not shown
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:7447366
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-25
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3277924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7447377
Age: embryonic day 16.5
Note: Sox2 was successfully deleted, with only a small number of Sox2-positive cells detectable.
Specimen Label: not shown
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
Probe: MGI:6863996
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7624246
Age: embryonic day 18.5
Image: S5D
Note: There were no differences in Sox2 staining of proximal epithelial cells observed in the mutant.
Specimen Label: S5D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5430034
Assay Type: Immunohistochemistry
Annotation Date: 2016-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3669911
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5811256
Age: embryonic day 7.25
Image: ED4g -/-
Note: Sox2 was not activated in primordial germ cells in the mutants.
Specimen Label: ED4g -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7447366
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-25
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3639224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7447377
Age: embryonic day 16.5
Note: Sox2 was successfully deleted, with only a small number of Sox2-positive cells detectable.
Specimen Label: not shown
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
Probe: MGI:6274516
Assay Type: Immunohistochemistry
Annotation Date: 2019-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6274527
Age: embryonic day 16.5
Image: 1H
Note: Authors report Tubb3-expressing cells co-expressing Sox2 found intermittently in the ventricular zone and subventricular zone.
Specimen Label: 1H
Detected: true
Specimen Num: 2
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Strain
MGI:5700642 | STOCK Tg(Sox2-Bgeo)1Skn/Cnrm
Attribute String: mutant stock, transgenic
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Publication
32905832 | J:300085
First Author: Porter L
Year: 2020
Journal: Semin Cancer Biol
Title: SOX2 and squamous cancers.
Volume: 67
Issue: Pt 1
Pages: 154-167
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GXD Expression
GXD Expression
Probe: MGI:5762877
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6763035
Age: embryonic day 12.5
Image: 9E
Note: In the apical regions, where the sensory precursors have ceased dividing, expression of Jag1 and Sox2 did not overlap.
Specimen Label: 9E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7789035
Assay Type: RNA in situ
Annotation Date: 2024-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7789036
Age: embryonic day 9.5
Image: S4A anterior control
Note: Sox2 is a proneurosensory marker with expression in the ventral region along the anterior-posterior axis at E9.5.
Specimen Label: S4A anterior control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7789035
Assay Type: RNA in situ
Annotation Date: 2024-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7789036
Age: embryonic day 9.5
Image: S4A mid-transverse control
Note: Sox2 is a proneurosensory marker with expression in the ventral region along the anterior-posterior axis at E9.5.
Specimen Label: S4A mid-transverse control
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7789035
Assay Type: RNA in situ
Annotation Date: 2024-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7789036
Age: embryonic day 9.5
Image: S4A posterior control
Note: Sox2 is a proneurosensory marker with expression in the ventral region along the anterior-posterior axis at E9.5.
Specimen Label: S4A posterior control
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6G'
Note: Sox2 was found expressed in the neural tube similar to, but at much lower levels than Zscan10.
Specimen Label: S6G'
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6M'
Note: Sox2 was found expressed in the neural tube similar to, but at much lower levels than Zscan10.
Specimen Label: S6M'
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6I'
Note: Sox2 was found expressed in the apical ectodermal ridge similar to, and with equivalent levels as, Zscan10.
Specimen Label: S6I'
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6192750
Assay Type: RNA in situ
Annotation Date: 2018-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6193855
Age: embryonic day 12.5
Image: S6O'
Note: Sox2 was found expressed in the apical ectodermal ridge similar to, and with equivalent levels as, Zscan10.
Specimen Label: S6O'
Detected: true
Specimen Num: 9
•
•
•
•
•
Publication
24094324 | J:201265
First Author: Andoniadou CL
Year: 2013
Journal: Cell Stem Cell
Title: Sox2(+) stem/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential.
Volume: 13
Issue: 4
Pages: 433-45
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5430034
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706716
Stage: TS16
Assay Id: MGI:6361504
Age: embryonic day 9.5
Image: S3D
Note: The combined Pdx1 and Sox9 deletion did not result in ectopic expression of the stomach marker Sox2 in the Pdx1+ domain.
Specimen Label: S3D
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6209827
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6209832
Age: embryonic day 11.5
Image: 4A
Note: The fraction of cells expressing low levels of Sox2 that were labelled by BrdU was 1.6-times greater than that of the cells expressing high levels of Sox2.
Specimen Label: 4A
Detected: true
Specimen Num: 5
•
•
•
•
•
Strain
MGI:5700502 | STOCK Sox2<tm2Skn>/Cnrm
Attribute String: targeted mutation, mutant stock
•
•
•
•
•
Publication
19605494 | J:152844
First Author: Driskell RR
Year: 2009
Journal: Development
Title: Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis.
Volume: 136
Issue: 16
Pages: 2815-23
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5762877
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6763035
Age: embryonic day 12.5
Image: 10H
Note: Jag1 and Sox2 exhibited largely overlapping expression in anterior and lateral cristae. In the anterior cristae, expression had a negative patch in the middle, whereas Sox2 expression did not.
Specimen Label: 10H
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5762877
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6763035
Age: embryonic day 12.5
Image: 10B
Note: Jag1 and Sox2 exhibited largely overlapping expression in posterior cristae and saccular macula. In the posterior cristae, expression had a negative patch in the middle, whereas Sox2 expression did not.
Specimen Label: 10B
Detected: true
Specimen Num: 5
•
•
•
•
•
Publication
19701198 | J:153116
First Author: Kuwabara T
Year: 2009
Journal: Nat Neurosci
Title: Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis.
Volume: 12
Issue: 9
Pages: 1097-105
•
•
•
•
•
Publication
28118374 | J:246292
First Author: Nishimura K
Year: 2017
Journal: PLoS One
Title: Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea.
Volume: 12
Issue: 1
Pages: e0170568
•
•
•
•
•
Publication
30523789 | J:352829
First Author: Ma G
Year: 2018
Journal: Cytotherapy
Title: Evaluation of the differentiation status of neural stem cells based on cell morphology and the expression of Notch and Sox2.
Volume: 20
Issue: 12
Pages: 1472-1485
•
•
•
•
•
Publication
27090805 | J:233750
First Author: Gu R
Year: 2016
Journal: Dev Biol
Title: Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti.
Volume: 414
Issue: 1
Pages: 72-84
•
•
•
•
•
Publication
- | J:306956
     
First Author: Mugele D
Year: 2021
Journal: bioRxiv
Title: Genetic approaches in mice demonstrate that neuro-mesodermal progenitors express T/Brachyury but not Sox2.
•
•
•
•
•
Publication
25026204 | J:214233
First Author: Tam WL
Year: 2014
Journal: Cancer Cell
Title: Sox2: masterminding the root of cancer.
Volume: 26
Issue: 1
Pages: 3-5
•
•
•
•
•
Publication
24094323 | J:202675
First Author: Rizzoti K
Year: 2013
Journal: Cell Stem Cell
Title: Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand.
Volume: 13
Issue: 4
Pages: 419-32
•
•
•
•
•
Publication
31422875 | J:282716
First Author: Song Y
Year: 2019
Journal: Mol Cell
Title: Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs.
Volume: 75
Issue: 5
Pages: 905-920.e6
•
•
•
•
•
Publication
29587142 | J:263872
First Author: Tata PR
Year: 2018
Journal: Dev Cell
Title: Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
Volume: 44
Issue: 6
Pages: 679-693.e5
•
•
•
•
•
Publication
25467916 | J:223859
First Author: Kareta MS
Year: 2015
Journal: Cell Stem Cell
Title: Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis.
Volume: 16
Issue: 1
Pages: 39-50
•
•
•
•
•
Publication
36054203 | J:355043
First Author: Ohmoto M
Year: 2022
Journal: PLoS One
Title: Maintenance and turnover of Sox2+ adult stem cells in the gustatory epithelium.
Volume: 17
Issue: 9
Pages: e0267683
•
•
•
•
•
Publication
32627901 | J:337397
First Author: Kwon OJ
Year: 2020
Journal: Stem Cells
Title: The Sca-1(+) and Sca-1(-) mouse prostatic luminal cell lineages are independently sustained.
Volume: 38
Issue: 11
Pages: 1479-1491
•
•
•
•
•
Publication
38320986 | J:352776
First Author: Ojeda-Alonso J
Year: 2024
Journal: Nat Commun
Title: Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception.
Volume: 15
Issue: 1
Pages: 898
•
•
•
•
•
Publication
30658984 | J:272620
 
First Author: Popa EM
Year: 2019
Journal: Development
Title: Revitalising the rudimentary replacement dentition in the mouse.
Volume: 146
Issue: 3
•
•
•
•
•
Publication
24508530 | J:208424
 
First Author: Yoshida M
Year: 2014
Journal: Mech Dev
Title: Regulation of mesodermal precursor production by low-level expression of B1 Sox genes in the caudal lateral epiblast.
Volume: 132
Pages: 59-68
•
•
•
•
•
Publication
30129215 | J:265456
First Author: Vilas JM
Year: 2018
Journal: Aging Cell
Title: Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging.
Volume: 17
Issue: 5
Pages: e12834
•
•
•
•
•
Publication
21245162 | J:168146
First Author: Teo AK
Year: 2011
Journal: Genes Dev
Title: Pluripotency factors regulate definitive endoderm specification through eomesodermin.
Volume: 25
Issue: 3
Pages: 238-50
•
•
•
•
•
Publication
36571357 | J:354601
First Author: Yang JL
Year: 2023
Journal: Neural Regen Res
Title: Transient neurogenesis in ischemic cortex from Sox2(+) astrocytes.
Volume: 18
Issue: 7
Pages: 1521-1526
•
•
•
•
•
Publication
23635313 | J:319488
First Author: Ni A
Year: 2013
Journal: Stem Cells Dev
Title: Facile and efficient reprogramming of ciliary body epithelial cells into induced pluripotent stem cells.
Volume: 22
Issue: 18
Pages: 2543-50
•
•
•
•
•
Publication
32294450 | J:305768
First Author: Selvadurai HJ
Year: 2020
Journal: Cell Rep
Title: Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor.
Volume: 31
Issue: 2
Pages: 107511
•
•
•
•
•
Publication
28892484 | J:264213
First Author: Zhang T
Year: 2017
Journal: PLoS Genet
Title: Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium.
Volume: 13
Issue: 9
Pages: e1006967
•
•
•
•
•
Publication
32147304 | J:289914
First Author: Brown RM 2nd
Year: 2020
Journal: Dev Biol
Title: Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.
Volume: 462
Issue: 1
Pages: 74-84
•
•
•
•
•
Publication
29335337 | J:262246
     
First Author: Emmerson E
Year: 2018
Journal: EMBO Mol Med
Title: Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.
•
•
•
•
•
Publication
36717694 | J:342647
First Author: Chakraborty S
Year: 2023
Journal: Nat Genet
Title: Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness.
Volume: 55
Issue: 2
Pages: 280-290
•
•
•
•
•
Publication
33127852 | J:297671
First Author: Chrysostomou E
Year: 2020
Journal: J Neurosci
Title: The Notch Ligand Jagged1 Is Required for the Formation, Maintenance, and Survival of Hensen's Cells in the Mouse Cochlea.
Volume: 40
Issue: 49
Pages: 9401-9413
•
•
•
•
•
Publication
29174333 | J:253900
First Author: Gadye L
Year: 2017
Journal: Cell Stem Cell
Title: Injury Activates Transient Olfactory Stem Cell States with Diverse Lineage Capacities.
Volume: 21
Issue: 6
Pages: 775-790.e9
•
•
•
•
•
Publication
31227770 | J:278634
First Author: Wilkerson BA
Year: 2019
Journal: Sci Rep
Title: Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea.
Volume: 9
Issue: 1
Pages: 9060
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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