|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 400 out of 461 for Spo11

<< First    < Previous  |  Next >    Last >>
0.045s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
11805049 | -
First Author: Kee K
Year: 2002
Journal: Genetics
Title: Functional interactions between SPO11 and REC102 during initiation of meiotic recombination in Saccharomyces cerevisiae.
Volume: 160
Issue: 1
Pages: 111-22
•
•
•
•
•
Gene
108700917 | spo11.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108702188 | spo11.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Protein
Q9WTK8-5
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
•
•
•
•
•
Protein
Q9WTK8-3
Organism: Mus musculus/domesticus
Length: 371  
Fragment?: false
•
•
•
•
•
Protein
Q9WTK8-2
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
•
•
•
•
•
Protein
Q9WTK8-4
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
•
•
•
•
•
Allele
Spo11<em1Rdco> | MGI:6842527
Name: SPO11 initiator of meiotic double stranded breaks; endonuclease-mediated mutation 1, R Daniel Camerini-Otero
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Publication
26917763 | -
First Author: Vrielynck N
Year: 2016
Journal: Science
Title: A DNA topoisomerase VI-like complex initiates meiotic recombination.
Volume: 351
Issue: 6276
Pages: 939-43
•
•
•
•
•
Allele
Spo11<+> | MGI:2438387
   
Name: SPO11 initiator of meiotic double stranded breaks; wild type
•
•
•
•
•
Allele
Spo11<tm1Mjn> | MGI:2178805
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 1, Maria Jasin
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Spo11<tm1Rdco> | MGI:3027823
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 1, R Daniel Camerini-Otero
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Spo11<tm1Nki> | MGI:4398954
 
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 1, The Netherlands Cancer Institute
Allele Type: Targeted
•
•
•
•
•
Allele
Spo11<tm1a(KOMP)Wtsi> | MGI:5319843
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
•
•
•
•
•
Allele
Spo11<tm1e(KOMP)Wtsi> | MGI:5319835
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Spo11<tm2a(KOMP)Wtsi> | MGI:5319885
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
•
•
•
•
•
Allele
Spo11<tm2e(KOMP)Wtsi> | MGI:5319866
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 2e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Spo11<tm1Bdm> | MGI:5432496
 
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 1, Bernard de Massy
Allele Type: Targeted
•
•
•
•
•
Allele
Spo11<tm2.1Rdco> | MGI:5490537
 
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 2.1, R Daniel Camerini-Otero
Allele Type: Targeted
•
•
•
•
•
Allele
Spo11<tm1.1Gvpc> | MGI:5538688
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 1.1, Galina Petukhova
Allele Type: Targeted
Attribute String: Hypomorph
•
•
•
•
•
Allele
Spo11<tm3Rdco> | MGI:5538689
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 3, R Daniel Camerini-Otero
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Spo11<tm2b(KOMP)Wtsi> | MGI:5605762
Name: SPO11 initiator of meiotic double stranded breaks; targeted mutation 2b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Spo11<em1Amp> | MGI:7281852
Name: SPO11 initiator of meiotic double stranded breaks; endonuclease-mediated mutation 1, Alberto M Pendas
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Spo11<em1Gpt> | MGI:7377307
Name: SPO11 initiator of meiotic double stranded breaks; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Spo11<em2Gpt> | MGI:7377308
Name: SPO11 initiator of meiotic double stranded breaks; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Spo11<em1Jcs> | MGI:7623838
Name: SPO11 initiator of meiotic double stranded breaks; endonuclease-mediated mutation 1, John C Schimenti
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
•
•
•
•
•
Allele
Spo11<em1Cya> | MGI:7796368
Name: SPO11 initiator of meiotic double stranded breaks; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Protein
Q80YR6
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
•
•
•
•
•
Strain
MGI:5431112 | B6.129X1-Spo11<tm1Mjn>/Orl
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:5442333 | B6.129X1-Spo11<tm1Mjn>/J
Attribute String: mutant strain, targeted mutation, congenic
•
•
•
•
•
Strain
MGI:6347418 | C57BL/6N-Spo11<tm2a(KOMP)Wtsi>/BayMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
•
•
•
•
•
Strain
MGI:5617612 | B6.129S6-Spo11<tm2.1Rdco>
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:5767448 | C57BL/6N-Spo11<tm2b(KOMP)Wtsi>/Bay
Attribute String: coisogenic, targeted mutation
•
•
•
•
•
Strain
MGI:7382334 | C57BL/6JGpt-Spo11<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Strain
MGI:7382335 | C57BL/6JGpt-Spo11<em2Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Strain
MGI:7836348 | C57BL/6JCya-Spo11<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6JOlaHsd
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: B6.129S6-Spo11
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: C57BL/6N-Spo11/Bay
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Allele
Tg(Slx-Spo11*)1Mjn | MGI:6296590
Name: transgene insertion 1, Maria Jasin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Genotype
Genotype
Symbol: Rec8/Rec8 Spo11/Spo11
Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Rad21l/Rad21l Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
17018031 | -
First Author: Stacey NJ
Year: 2006
Journal: Plant J
Title: Arabidopsis SPO11-2 functions with SPO11-1 in meiotic recombination.
Volume: 48
Issue: 2
Pages: 206-16
•
•
•
•
•
Protein Domain
IPR034566 | MTOPVIB_plant
Type: Family
Description: MTOPVIB (meiotic topoisomerase VIB-like) is a structural homologue of the archaeal topo VIB subunit []. MTOPVIB forms a complex with the two Arabidopsis thaliana SPO11 orthologues (SPO11-1 and SPO11-2) and is essential for meiotic DSB formation []. The SPO11 protein catalyzes the formation of meiotic DNA double strand breaks (DSBs) and it is the eukaryotic homologue of the archaeal DNA topoisomerase VIA.
•
•
•
•
•
Genotype
Genotype
Symbol: Mael/Mael Spo11/Spo11
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Hormad1/Hormad1 Spo11/Spo11
Background: involves: 129/Sv * BALB/c * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Hormad1/Hormad1 Spo11/Spo11
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6JOlaHsd
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11 Syce2/Syce2
Background: involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6JOlaHsd
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Hormad2/Hormad2 Spo11/Spo11
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6JOlaHsd
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Hormad2/Hormad2 Spo11/Spo11
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Hormad2/Hormad2<+> Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Hormad2/Hormad2 Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Psmc3ip/Psmc3ip Spo11/Spo11
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Hormad1/Hormad1 Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Meioc/Meioc Spo11/Spo11
Background: involves: 129X1/SvJ * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Mcmdc2/Mcmdc2 Spo11/Spo11
Background: involves: 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6N * CD-1
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11<+>
Background: B6.Cg-Spo11
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11<+>
Background: C57BL/6N-Spo11/Bay
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11<+>
Background: involves: 129X1/SvJ * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Allele
Tg(Spo11-cre)D5Mpel | MGI:4850038
Name: transgene insertion D5, Manuela Pellegrini
Allele Type: Transgenic
Attribute String: Recombinase
•
•
•
•
•
Allele
Tg(Spo11-cre)1Rsw | MGI:5484745
Name: transgene insertion 1, Robert S Weiss
Allele Type: Transgenic
Attribute String: Recombinase
•
•
•
•
•
Strain
MGI:6281959 | STOCK Tg(Spo11-cre)1Rsw/PecoJ
Attribute String: transgenic, mutant stock
•
•
•
•
•
Genotype
Genotype
Symbol: Rad50/Rad50<+> Spo11/Spo11
Background: involves: 129/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spo11/Spo11<+> Stag3/Stag3
Background: B6.Cg-Spo11 Stag3/2J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Protein
J3QMY9
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
•
•
•
•
•
Protein
A0A182DWE7
Organism: Mus musculus/domesticus
Length: 753  
Fragment?: false
•
•
•
•
•
Protein Domain
IPR028040 | TopoVIB-like
Type: Family
Description: This family of animal proteins is known as TOPOVIB-like as it shares strong structural similarity to the TopoVI DNA topoisomerase subunit B. TOPOVIB-like interacts and forms a complex with SPO11 and is required for meiotic DNA double-strand break formation []. TOPOVIB-like may be involved in the regulation of DNA cleavage.
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom