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Search results 301 to 353 out of 353 for Spr

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Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 313  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 313  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: false
Publication
First Author: Lim J
Year: 2002
Journal: Mol Cell Biol
Title: The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes.
Volume: 22
Issue: 22
Pages: 7953-66
Publication
First Author: King JA
Year: 2005
Journal: Biochem J
Title: Distinct requirements for the Sprouty domain for functional activity of Spred proteins.
Volume: 388
Issue: Pt 2
Pages: 445-54
Publication
First Author: Lim J
Year: 2000
Journal: J Biol Chem
Title: Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain.
Volume: 275
Issue: 42
Pages: 32837-45
Protein Domain
Type: Family
Description: Sprouty (Spry) and Spred (Sprouty related EVH1 domain) proteins have been identified as inhibitors of the Ras/mitogen-activated protein kinase(MAPK) cascade, a pathway crucial for developmental processes initiated by activation of various receptor tyrosine kinases [, ]. These proteins share a conserved, C-terminal cysteine-rich region, the SPR domain. This domain has been defined as a novel cytosol to membrane translocation domain [, , , ]. It has been found to be a PtdIns(4,5)P2-binding domain that targets the proteins to a cellular localization that maximizes their inhibitory potential [, ]. It also mediates homodimer formation of these proteins [, ].The SPR domain can occur in association with the WH1 domain (see ) (located in the N-terminal part of the proteins) in the Spred proteins.
Publication
First Author: Harmer NJ
Year: 2005
Journal: FEBS Lett
Title: 1.15 A crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family.
Volume: 579
Issue: 5
Pages: 1161-6
Protein
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
Publication
First Author: Hanafusa H
Year: 2002
Journal: Nat Cell Biol
Title: Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.
Volume: 4
Issue: 11
Pages: 850-8
Publication
First Author: Yap BK
Year: 2016
Journal: FEBS Lett
Title: Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction.
Volume: 590
Issue: 6
Pages: 696-704
Protein
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 408  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 444  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 408  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 437  
Fragment?: false
Publication
First Author: Jin HK
Year: 1999
Journal: J Virol
Title: Identification of the murine Mx2 gene: interferon-induced expression of the Mx2 protein from the feral mouse gene confers resistance to vesicular stomatitis virus.
Volume: 73
Issue: 6
Pages: 4925-30
Publication
First Author: Goulding M
Year: 1993
Journal: Genomics
Title: Analysis of the Pax-3 gene in the mouse mutant splotch.
Volume: 17
Issue: 2
Pages: 355-63
Publication
First Author: Epstein DJ
Year: 1991
Journal: Genomics
Title: Molecular characterization of a deletion encompassing the splotch mutation on mouse chromosome 1.
Volume: 10
Issue: 1
Pages: 89-93
Publication
First Author: Latremoliere A
Year: 2015
Journal: Neuron
Title: Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Volume: 86
Issue: 6
Pages: 1393-406
Protein
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Wilkie TM
Year: 1993
Journal: Genomics
Title: Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors.
Volume: 18
Issue: 2
Pages: 175-84
Publication
First Author: Vogan KJ
Year: 1993
Journal: Genomics
Title: The splotch-delayed (Spd) mouse mutant carries a point mutation within the paired box of the Pax-3 gene.
Volume: 17
Issue: 2
Pages: 364-9
Publication
First Author: Miyagi Y
Year: 2002
Journal: J Neurosci
Title: Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit.
Volume: 22
Issue: 3
Pages: 803-14
Publication
First Author: Kato R
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation.
Volume: 302
Issue: 4
Pages: 767-72
Publication
First Author: Epstein DJ
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant.
Volume: 90
Issue: 2
Pages: 532-6
Publication
First Author: Luo J
Year: 2020
Journal: Br J Pharmacol
Title: Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.
Volume: 177
Issue: 19
Pages: 4464-4480
Publication
First Author: Blum AM
Year: 1999
Journal: J Immunol
Title: The substance P receptor is necessary for a normal granulomatous response in murine schistosomiasis mansoni.
Volume: 162
Issue: 10
Pages: 6080-5
Publication
First Author: Cronin SJF
Year: 2018
Journal: Nature
Title: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Volume: 563
Issue: 7732
Pages: 564-568
Publication
First Author: Boren J
Year: 2001
Journal: J Biol Chem
Title: Binding of low density lipoproteins to lipoprotein lipase is dependent on lipids but not on apolipoprotein B.
Volume: 276
Issue: 29
Pages: 26916-22
Publication
First Author: el-Shazly S
Year: 2001
Journal: Biochem Genet
Title: Male hybrid sterility of mice with the genomic region of the KitW mutation and the KitS allele from Mus spretus.
Volume: 39
Issue: 3-4
Pages: 127-37
Publication
First Author: Epstein DJ
Year: 1994
Journal: Genomics
Title: Characterization of a region-specific library of microclones in the vicinity of the Bcg and splotch loci on mouse chromosome 1.
Volume: 19
Issue: 1
Pages: 163-6
Publication
First Author: Matsumura K
Year: 2007
Journal: J Biol Chem
Title: Carbohydrate binding specificity of a fucose-specific lectin from Aspergillus oryzae: a novel probe for core fucose.
Volume: 282
Issue: 21
Pages: 15700-8
Publication
First Author: Ling J
Year: 2008
Journal: J Biol Chem
Title: Structural constraints for the binding of short peptides to claudin-4 revealed by surface plasmon resonance.
Volume: 283
Issue: 45
Pages: 30585-95
Publication
First Author: Lund-Katz S
Year: 2010
Journal: J Lipid Res
Title: Surface plasmon resonance analysis of the mechanism of binding of apoA-I to high density lipoprotein particles.
Volume: 51
Issue: 3
Pages: 606-17
Publication
First Author: Wegener H
Year: 2013
Journal: Biochem Biophys Res Commun
Title: The vWFA2 domain of type VII collagen is responsible for collagen binding.
Volume: 430
Issue: 2
Pages: 449-53
Publication
First Author: Chehboun S
Year: 2017
Journal: J Biol Chem
Title: Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6 trans-signaling.
Volume: 292
Issue: 16
Pages: 6644-6656
Publication
First Author: Callebaut I
Year: 1998
Journal: FEBS Lett
Title: EVH1/WH1 domains of VASP and WASP proteins belong to a large family including Ran-binding domains of the RanBP1 family.
Volume: 441
Issue: 2
Pages: 181-5
Publication
First Author: Makino CL
Year: 2012
Journal: PLoS One
Title: Enzymatic relay mechanism stimulates cyclic GMP synthesis in rod photoresponse: biochemical and physiological study in guanylyl cyclase activating protein 1 knockout mice.
Volume: 7
Issue: 10
Pages: e47637
Publication
First Author: Pankonien I
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cavβ₂.
Volume: 421
Issue: 2
Pages: 184-9
Publication
First Author: Ozawa T
Year: 2012
Journal: Biochem Biophys Res Commun
Title: The binding affinity of a soluble TCR-Fc fusion protein is significantly improved by crosslinkage with an anti-Cβ antibody.
Volume: 422
Issue: 2
Pages: 245-9
Publication
First Author: Ni T
Year: 2017
Journal: Biochem J
Title: Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain.
Volume: 474
Issue: 4
Pages: 539-556
Publication  
First Author: Malerba F
Year: 2016
Journal: Front Mol Neurosci
Title: NGF and proNGF Reciprocal Interference in Immunoassays: Open Questions, Criticalities, and Ways Forward.
Volume: 9
Pages: 63
Publication
First Author: Cattanach BM
Year: 1993
Journal: Mouse Genome
Title: A further mutation at the splotch locus
Volume: 91
Issue: 1
Pages: 115-16
Publication
First Author: Hamer RD
Year: 2003
Journal: J Gen Physiol
Title: Multiple steps of phosphorylation of activated rhodopsin can account for the reproducibility of vertebrate rod single-photon responses.
Volume: 122
Issue: 4
Pages: 419-44
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Peters J
Year: 1995
Journal: Mouse Genome
Title: Genetic and phenotypic analysis of Del(1)Spr3H and Pax3Sp-4H
Volume: 93
Issue: 4
Pages: 1041-3
Publication
First Author: Malas S
Year: 1995
Journal: Mouse Genome
Title: PCR Markers associated with the mouse nicotinic-acetylcholine-receptor-subunit genes alpha-4, alpha-7 and beta-4 on mouse Chromosomes 2, 7, and 9
Volume: 93
Issue: 2
Pages: 433-5