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Search results 301 to 385 out of 385 for Srgap2

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0.023s
Type Details Score
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7621450
Age: embryonic day 12.5
Specimen Label: Table 1 E12.5
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7621450
Age: embryonic day 13.5
Specimen Label: Table 1 E13.5
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7621450
Age: postnatal day 7
Image: 1K
Specimen Label: 1K
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7621450
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7621450
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: true
Specimen Num: 26
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3590822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621450
Age: embryonic day 14.5
Specimen Label: Table 1 E14.5
Detected: true
Specimen Num: 23
GXD Expression      
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3590824
Stage: TS24
Assay Id: MGI:7621450
Age: embryonic day 16.5
Specimen Label: Table 1 E16.5
Detected: false
Specimen Num: 24
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3590827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7621450
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: true
Specimen Num: 25
GXD Expression      
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3590828
Stage: TS28
Assay Id: MGI:7621450
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: false
Specimen Num: 26
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7621450
Age: embryonic day 12.5
Note: Expression is in the cerebellar nuclei differentiating zone and cerebellar plate.
Specimen Label: Table 1 E12.5
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3521727
Stage: TS27
Assay Id: MGI:7621450
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: false
Specimen Num: 25
GXD Expression      
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3521728
Stage: TS28
Assay Id: MGI:7621450
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: false
Specimen Num: 26
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7621450
Age: embryonic day 13.5
Note: Expression is in the retinal ganglion layer, absent in the neuroblastic layer.
Specimen Label: Table 1 E13.5
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7621450
Age: embryonic day 14.5
Note: Expression is in the retinal ganglion layer, absent in the neuroblastic layer.
Specimen Label: Table 1 E14.5
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621450
Age: embryonic day 14.5
Image: 5B
Specimen Label: 5B
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7621450
Age: postnatal day 1
Image: 5E
Specimen Label: 5E
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621450
Age: embryonic day 14.5
Specimen Label: Table 1 E14.5
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7621450
Age: embryonic day 16.5
Specimen Label: Table 1 E16.5
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7621450
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: true
Specimen Num: 25
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7621450
Age: embryonic day 13.5
Note: Expression is in the mitral layer and is absent in the granule cell layer.
Specimen Label: Table 1 E13.5
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7621450
Age: embryonic day 14.5
Note: Expression is in the mitral layer and is absent in the granule cell layer.
Specimen Label: Table 1 E14.5
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:7619949
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3826128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7621450
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: true
Specimen Num: 26
Publication
First Author: Wong K
Year: 2001
Journal: Cell
Title: Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
Volume: 107
Issue: 2
Pages: 209-21
Publication
First Author: Rogg M
Year: 2021
Journal: J Am Soc Nephrol
Title: SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.
Volume: 32
Issue: 3
Pages: 563-579
Publication
First Author: Bacon C
Year: 2011
Journal: PLoS One
Title: Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.
Volume: 6
Issue: 5
Pages: e19887
Publication
First Author: Carbonell AU
Year: 2019
Journal: Nat Commun
Title: Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.
Volume: 10
Issue: 1
Pages: 3529
Publication
First Author: Chan DC
Year: 1996
Journal: EMBO J
Title: Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.
Volume: 15
Issue: 5
Pages: 1045-54
Publication
First Author: Roma G
Year: 2007
Journal: Genome Res
Title: A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells.
Volume: 17
Issue: 7
Pages: 1051-60
Publication
First Author: Mattar P
Year: 2004
Journal: Dev Biol
Title: A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.
Volume: 273
Issue: 2
Pages: 373-89
Publication
First Author: Da Cruz S
Year: 2003
Journal: J Biol Chem
Title: Proteomic analysis of the mouse liver mitochondrial inner membrane.
Volume: 278
Issue: 42
Pages: 41566-71
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Coutinho-Budd J
Year: 2012
Journal: J Cell Sci
Title: The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.
Volume: 125
Issue: Pt 14
Pages: 3390-401
Protein
Organism: Mus musculus/domesticus
Length: 1099  
Fragment?: false
Allele
Name: SLIT-ROBO Rho GTPase activating protein 2; gene trap XH102, BayGenomics
Allele Type: Gene trapped
Attribute String: Hypomorph, Reporter
Strain
Attribute String: gene trap, mutant stock
Genotype
Symbol: Srgap2/Srgap2
Background: B6;129P2-Srgap2/Mmucd
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Endris V
Year: 2011
Journal: J Cell Sci
Title: SrGAP3 interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions.
Volume: 124
Issue: Pt 23
Pages: 3941-55
Protein Domain
Type: Domain
Description: This entry represents the SH3 domain found in srGAP proteins 1, 2 and 3. srGAP1 (also called ARHGAP13) is a key GTPase activating protein (GAP) downstream of Slit-Robo pathway, and has been shown to inhibit neuronal migration and glioma cell invasion by reducing the activation of Cdc42 []. srGAP2 (ARHGAP34) regulates neuronal morphogenesis through the ability of its F-BAR domain to regulate membrane deformation and induce filopodia formation []. srGAP3 (ARHGAP14) interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions []. The SLIT-ROBO Rho GTPase-activating protein (srGAP) family consists of four members: srGAP1, -2, -3 and -4. They contain F-BAR, RhoGAP and SH3 domains. Their RhoGAP domain is involved in negative regulation of Rho GTPase activities important for cytoskeleton rearrangement []. The srGAP family members have an "inverse F-BAR"or IF-BAR domain that is distinct from other F-BAR domains such as FBP17. They are multifunctional adaptor proteins involved in various aspects of neuronal development [].
Publication
First Author: Franceschetti T
Year: 2013
Journal: J Biol Chem
Title: miR-29 promotes murine osteoclastogenesis by regulating osteoclast commitment and migration.
Volume: 288
Issue: 46
Pages: 33347-60
Protein
Organism: Mus musculus/domesticus
Length: 1062  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1085  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1075  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1099  
Fragment?: false