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Search results 301 to 400 out of 513 for Stk11

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Type Details Score
Publication
21283818 | J:169565
First Author: Shorning BY
Year: 2011
Journal: PLoS One
Title: Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder.
Volume: 6
Issue: 1
Pages: e16209
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Publication
20452353 | J:337198
First Author: Morton JP
Year: 2010
Journal: Gastroenterology
Title: LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest.
Volume: 139
Issue: 2
Pages: 586-97, 597.e1-6
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Publication
36715544 | J:334469
First Author: Stein BD
Year: 2023
Journal: Cancer Discov
Title: LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
Volume: 13
Issue: 4
Pages: 1002-1025
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Publication
23715154 | J:203634
First Author: Liu Y
Year: 2013
Journal: Cancer Discov
Title: Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.
Volume: 3
Issue: 8
Pages: 870-9
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Publication
35228570 | J:321839
First Author: Murray CW
Year: 2022
Journal: Nat Commun
Title: LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer.
Volume: 13
Issue: 1
Pages: 1090
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Publication
24458094 | J:288211
First Author: Zhang W
Year: 2014
Journal: Cell Res
Title: VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex.
Volume: 24
Issue: 3
Pages: 331-43
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Publication
28754670 | J:245578
First Author: Liu Y
Year: 2017
Journal: Cancer Res
Title: Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma.
Volume: 77
Issue: 18
Pages: 5068-5076
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Publication
27643638 | J:240510
First Author: Svensson RU
Year: 2016
Journal: Nat Med
Title: Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.
Volume: 22
Issue: 10
Pages: 1108-1119
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Publication
26178787 | J:222466
First Author: Chiou SH
Year: 2015
Journal: Genes Dev
Title: Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
Volume: 29
Issue: 14
Pages: 1576-85
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Publication
27728797 | J:236719
First Author: Murray NR
Year: 2016
Journal: Cancer Cell
Title: SOX2 Determines Lineage Restriction: Modeling Lung Squamous Cell Carcinoma in the Mouse.
Volume: 30
Issue: 4
Pages: 505-507
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Publication
23352126 | J:194330
First Author: Shackelford DB
Year: 2013
Journal: Cancer Cell
Title: LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin.
Volume: 23
Issue: 2
Pages: 143-58
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Publication
29233960 | J:254092
First Author: Winters IP
Year: 2017
Journal: Nat Commun
Title: Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.
Volume: 8
Issue: 1
Pages: 2053
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Publication
28530655 | J:254091
First Author: Rogers ZN
Year: 2017
Journal: Nat Methods
Title: A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo.
Volume: 14
Issue: 7
Pages: 737-742
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Publication
20956321 | J:166159
First Author: Gao Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling.
Volume: 107
Issue: 44
Pages: 18892-7
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Publication
22425996 | J:182575
First Author: Chen Z
Year: 2012
Journal: Nature
Title: A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
Volume: 483
Issue: 7391
Pages: 613-7
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Publication
30205046 | J:265468
First Author: Kitajima S
Year: 2018
Journal: Cancer Cell
Title: Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS.
Volume: 34
Issue: 3
Pages: 439-452.e6
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Publication
25519892 | J:223245
 
First Author: Herter-Sprie GS
Year: 2014
Journal: Nat Commun
Title: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models.
Volume: 5
Pages: 5870
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Publication
37695905 | J:346096
First Author: Yousefi M
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Fully accessible fitness landscape of oncogene-negative lung adenocarcinoma.
Volume: 120
Issue: 38
Pages: e2303224120
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Publication
28099846 | J:254560
First Author: Nagaraj AS
Year: 2017
Journal: Cell Rep
Title: Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1.
Volume: 18
Issue: 3
Pages: 673-684
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Publication
36702816 | J:332808
First Author: Bhatt V
Year: 2023
Journal: Cell Death Dis
Title: Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors.
Volume: 14
Issue: 1
Pages: 61
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Publication
33924999 | J:308906
 
First Author: Hsieh MJ
Year: 2021
Journal: Int J Mol Sci
Title: Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice.
Volume: 22
Issue: 9
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Publication
31204282 | J:282006
First Author: Li M
Year: 2019
Journal: Cell Metab
Title: Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
Volume: 30
Issue: 3
Pages: 508-524.e12
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Publication
31160601 | J:297270
First Author: Waters LR
Year: 2019
Journal: Sci Rep
Title: Ampk regulates IgD expression but not energy stress with B cell activation.
Volume: 9
Issue: 1
Pages: 8176
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Publication
25157091 | J:249495
First Author: Samovski D
Year: 2015
Journal: Diabetes
Title: Regulation of AMPK activation by CD36 links fatty acid uptake to β-oxidation.
Volume: 64
Issue: 2
Pages: 353-9
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Publication
30830877 | J:292166
First Author: Han Y
Year: 2019
Journal: J Clin Invest
Title: Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation.
Volume: 129
Issue: 5
Pages: 1895-1909
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Publication
23931756 | J:200988
First Author: Mounier R
Year: 2013
Journal: Cell Metab
Title: AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration.
Volume: 18
Issue: 2
Pages: 251-64
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Publication
28381544 | J:242296
First Author: Li R
Year: 2017
Journal: Cancer Res
Title: Modulation of Bax and mTOR for Cancer Therapeutics.
Volume: 77
Issue: 11
Pages: 3001-3012
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Publication
28387316 | J:253496
 
First Author: Zhang H
Year: 2017
Journal: Nat Commun
Title: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Volume: 8
Pages: 14922
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Publication
18387000 | J:136150
First Author: Huang X
Year: 2008
Journal: Biochem J
Title: Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Volume: 412
Issue: 2
Pages: 211-21
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Publication
29152604 | J:329366
First Author: Jia C
Year: 2017
Journal: Hepatol Commun
Title: Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development.
Volume: 1
Issue: 2
Pages: 153-167
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Publication
21124450 | J:165090
First Author: Nakada D
Year: 2010
Journal: Nature
Title: Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells.
Volume: 468
Issue: 7324
Pages: 653-8
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Publication
21135058 | J:169259
First Author: Sun G
Year: 2011
Journal: Dis Model Mech
Title: RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis.
Volume: 4
Issue: 2
Pages: 193-202
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Publication
17855357 | J:126943
First Author: Göransson O
Year: 2007
Journal: J Biol Chem
Title: Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.
Volume: 282
Issue: 45
Pages: 32549-60
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Publication
29466728 | J:270803
First Author: Maillet V
Year: 2018
Journal: Cell Rep
Title: LKB1 as a Gatekeeper of Hepatocyte Proliferation and Genomic Integrity during Liver Regeneration.
Volume: 22
Issue: 8
Pages: 1994-2005
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Publication
20577053 | J:163780
First Author: Foretz M
Year: 2010
Journal: J Clin Invest
Title: Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Volume: 120
Issue: 7
Pages: 2355-69
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Publication
25070369 | J:217566
First Author: Kone M
Year: 2014
Journal: FASEB J
Title: LKB1 and AMPK differentially regulate pancreatic β-cell identity.
Volume: 28
Issue: 11
Pages: 4972-85
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Publication
28723898 | J:253142
First Author: Zhang CS
Year: 2017
Journal: Nature
Title: Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
Volume: 548
Issue: 7665
Pages: 112-116
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Publication
32378514 | J:292473
   
First Author: Burger CA
Year: 2020
Journal: Elife
Title: LKB1 coordinates neurite remodeling to drive synapse layer emergence in the outer retina.
Volume: 9
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Publication
29483507 | J:259698
First Author: Flowers EM
Year: 2018
Journal: Nat Commun
Title: Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.
Volume: 9
Issue: 1
Pages: 814
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Publication
36384136 | J:332627
First Author: Zhou Q
Year: 2022
Journal: Mol Cell
Title: Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha.
Volume: 82
Issue: 24
Pages: 4700-4711.e12
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Publication
26363011 | J:226783
First Author: Zhang W
Year: 2015
Journal: Cancer Res
Title: YAP promotes malignant progression of Lkb1-deficient lung adenocarcinoma through downstream regulation of survivin.
Volume: 75
Issue: 21
Pages: 4450-7
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Publication
25936644 | J:221407
First Author: Li F
Year: 2015
Journal: Cancer Cell
Title: LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response.
Volume: 27
Issue: 5
Pages: 698-711
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Publication
38805014 | J:358843
 
First Author: Xue Y
Year: 2024
Journal: J Exp Med
Title: TET2-STAT3-CXCL5 nexus promotes neutrophil lipid transfer to fuel lung adeno-to-squamous transition.
Volume: 221
Issue: 7
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Publication
19966866 | J:160400
First Author: Liang MC
Year: 2010
Journal: Oncogene
Title: TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Volume: 29
Issue: 11
Pages: 1588-97
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Publication
25002183 | J:215643
First Author: Zhang CS
Year: 2014
Journal: Cell Metab
Title: The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism.
Volume: 20
Issue: 3
Pages: 526-40
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Publication
27760313 | J:240755
First Author: Woller A
Year: 2016
Journal: Cell Rep
Title: A Mathematical Model of the Liver Circadian Clock Linking Feeding and Fasting Cycles to Clock Function.
Volume: 17
Issue: 4
Pages: 1087-1097
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Publication
33535040 | J:304281
First Author: Burger CA
Year: 2021
Journal: Cell Rep
Title: LKB1 and AMPK instruct cone nuclear position to modify visual function.
Volume: 34
Issue: 5
Pages: 108698
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Publication
30692209 | J:272559
First Author: Bhatt V
Year: 2019
Journal: Genes Dev
Title: Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis.
Volume: 33
Issue: 3-4
Pages: 150-165
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Publication
32347900 | J:321185
First Author: Lin D
Year: 2020
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Dispensable role of CCL28 in Kras-mutated non-small cell lung cancer mouse models.
Volume: 52
Issue: 6
Pages: 691-694
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Publication
30279167 | J:281798
 
First Author: Moral-Sanz J
Year: 2018
Journal: Sci Signal
Title: The LKB1-AMPK-α1 signaling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria.
Volume: 11
Issue: 550
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Publication
22454291 | J:187027
First Author: Peng IC
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Glucagon regulates ACC activity in adipocytes through the CAMKKβ/AMPK pathway.
Volume: 302
Issue: 12
Pages: E1560-8
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Publication
18381428 | J:133330
First Author: Pearson HB
Year: 2008
Journal: Cancer Res
Title: Lkb1 deficiency causes prostate neoplasia in the mouse.
Volume: 68
Issue: 7
Pages: 2223-32
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Publication
25366347 | J:218267
First Author: Morrison A
Year: 2015
Journal: FASEB J
Title: Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart.
Volume: 29
Issue: 2
Pages: 408-17
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Publication
30208308 | J:270632
First Author: Kuwako KI
Year: 2018
Journal: Cell Rep
Title: The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells.
Volume: 24
Issue: 11
Pages: 2808-2818.e4
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Publication
26549569 | J:250173
 
First Author: Men Y
Year: 2015
Journal: Sci Rep
Title: LKB1 Regulates Cerebellar Development by Controlling Sonic Hedgehog-mediated Granule Cell Precursor Proliferation and Granule Cell Migration.
Volume: 5
Pages: 16232
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Publication
19274086 | J:277854
First Author: Esteve-Puig R
Year: 2009
Journal: PLoS One
Title: Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAF.
Volume: 4
Issue: 3
Pages: e4771
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Publication
18974775 | J:158092
First Author: Huang Q
Year: 2009
Journal: Cell Death Differ
Title: A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress.
Volume: 16
Issue: 2
Pages: 264-77
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Publication
24093678 | J:205915
First Author: Zhang YL
Year: 2013
Journal: Cell Metab
Title: AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation.
Volume: 18
Issue: 4
Pages: 546-55
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Publication
26625127 | J:230047
First Author: Griss T
Year: 2015
Journal: PLoS Biol
Title: Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis.
Volume: 13
Issue: 12
Pages: e1002309
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Publication
21383064 | J:172815
First Author: Wolff NC
Year: 2011
Journal: Mol Cell Biol
Title: Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
Volume: 31
Issue: 9
Pages: 1870-84
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Publication
21487392 | J:172064
First Author: Cao Y
Year: 2011
Journal: EMBO J
Title: LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection.
Volume: 30
Issue: 10
Pages: 2083-93
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Publication
19254698 | J:147384
First Author: Awazawa M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.
Volume: 382
Issue: 1
Pages: 51-6
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Publication
27679742 | J:243707
First Author: Camacho P
Year: 2016
Journal: Am J Cardiovasc Dis
Title: Small mammalian animal models of heart disease.
Volume: 6
Issue: 3
Pages: 70-80
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Publication
24953650 | J:266020
First Author: Mukhopadhyay A
Year: 2014
Journal: Cell Rep
Title: Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer.
Volume: 8
Issue: 1
Pages: 40-9
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Publication
31412252 | J:282694
First Author: Hsieh MH
Year: 2019
Journal: Cell Rep
Title: p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas.
Volume: 28
Issue: 7
Pages: 1860-1878.e9
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Publication
29514069 | J:260521
First Author: Masand R
Year: 2018
Journal: Cell Metab
Title: Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits.
Volume: 27
Issue: 3
Pages: 616-629.e4
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Publication
23241891 | J:191723
First Author: MacKenzie KF
Year: 2013
Journal: J Immunol
Title: PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway.
Volume: 190
Issue: 2
Pages: 565-77
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Publication
24768298 | J:215277
First Author: Luan B
Year: 2014
Journal: Cell Metab
Title: Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4.
Volume: 19
Issue: 6
Pages: 1058-65
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Publication
28621313 | J:250354
 
First Author: Wu D
Year: 2017
Journal: Nat Commun
Title: Lkb1 maintains Treg cell lineage identity.
Volume: 8
Pages: 15876
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Publication
31167140 | J:281285
First Author: Timilshina M
Year: 2019
Journal: Cell Rep
Title: Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.
Volume: 27
Issue: 10
Pages: 2948-2961.e7
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Publication
25252692 | J:220627
First Author: Burd CE
Year: 2014
Journal: Cancer Discov
Title: Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma.
Volume: 4
Issue: 12
Pages: 1418-29
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Publication
23266956 | J:195229
First Author: Lo B
Year: 2012
Journal: J Cell Biol
Title: Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.
Volume: 199
Issue: 7
Pages: 1117-30
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Publication
22698401 | J:189285
First Author: Liu W
Year: 2012
Journal: Cancer Cell
Title: LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.
Volume: 21
Issue: 6
Pages: 751-64
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Publication
23332765 | J:193498
First Author: Burd CE
Year: 2013
Journal: Cell
Title: Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.
Volume: 152
Issue: 1-2
Pages: 340-51
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Publication
24170201 | J:206514
First Author: Tanwar PS
Year: 2014
Journal: Carcinogenesis
Title: Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer.
Volume: 35
Issue: 3
Pages: 546-53
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Publication
24531128 | J:206810
 
First Author: Han X
Year: 2014
Journal: Nat Commun
Title: Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma.
Volume: 5
Pages: 3261
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Publication
23791179 | J:200007
First Author: Courchet J
Year: 2013
Journal: Cell
Title: Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture.
Volume: 153
Issue: 7
Pages: 1510-25
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Publication
34369094 | J:354596
First Author: Wang P
Year: 2021
Journal: Adv Sci (Weinh)
Title: IL-36γ and IL-36Ra Reciprocally Regulate NSCLC Progression by Modulating GSH Homeostasis and Oxidative Stress-Induced Cell Death.
Volume: 8
Issue: 19
Pages: e2101501
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Publication
29875463 | J:271523
First Author: Wang G
Year: 2018
Journal: Nat Med
Title: Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle.
Volume: 24
Issue: 6
Pages: 770-781
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Publication
24362629 | J:208277
First Author: Mohseni M
Year: 2014
Journal: Nat Cell Biol
Title: A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.
Volume: 16
Issue: 1
Pages: 108-17
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Publication
35504291 | J:325477
First Author: Best SA
Year: 2022
Journal: Cell Metab
Title: Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer.
Volume: 34
Issue: 6
Pages: 874-887.e6
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Publication
33257678 | J:299823
First Author: Zhang M
Year: 2020
Journal: Nat Commun
Title: CCL7 recruits cDC1 to promote antitumor immunity and facilitate checkpoint immunotherapy to non-small cell lung cancer.
Volume: 11
Issue: 1
Pages: 6119
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Publication
30415923 | J:272057
First Author: Eichner LJ
Year: 2019
Journal: Cell Metab
Title: Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models.
Volume: 29
Issue: 2
Pages: 285-302.e7
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Publication
29610476 | J:260935
First Author: Rogers ZN
Year: 2018
Journal: Nat Genet
Title: Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice.
Volume: 50
Issue: 4
Pages: 483-486
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Publication
32571479 | J:292176
   
First Author: Contat C
Year: 2020
Journal: Elife
Title: Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth.
Volume: 9
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Publication
37062029 | J:336554
First Author: DeBlasi JM
Year: 2023
Journal: Cancer Res
Title: Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression.
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