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Search results 301 to 400 out of 746 for Syk

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Type Details Score
Publication
15985541 | J:119538
First Author: Liu J
Year: 2005
Journal: Blood
Title: Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner.
Volume: 106
Issue: 8
Pages: 2750-6
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Publication
18356083 | J:134528
First Author: Yasuda T
Year: 2008
Journal: Immunity
Title: Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.
Volume: 28
Issue: 4
Pages: 499-508
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Publication
36662229 | J:336245
 
First Author: Hayward DA
Year: 2023
Journal: J Exp Med
Title: B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice.
Volume: 220
Issue: 3
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Publication
20308364 | J:159176
First Author: Henderson RB
Year: 2010
Journal: J Exp Med
Title: A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival.
Volume: 207
Issue: 4
Pages: 837-53
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Publication
14564011 | J:86765
First Author: Walmsley MJ
Year: 2003
Journal: Science
Title: Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling.
Volume: 302
Issue: 5644
Pages: 459-62
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Publication
23200858 | J:277945
First Author: Jhingran A
Year: 2012
Journal: Cell Rep
Title: Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung.
Volume: 2
Issue: 6
Pages: 1762-73
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Publication
10358768 | J:55440
 
First Author: Kurosaki T
Year: 1999
Journal: Annu Rev Immunol
Title: Genetic analysis of B cell antigen receptor signaling.
Volume: 17
Pages: 555-92
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Publication
23395392 | J:227372
First Author: Heit B
Year: 2013
Journal: Dev Cell
Title: Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization.
Volume: 24
Issue: 4
Pages: 372-83
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Publication
19139169 | J:144021
First Author: Werninghaus K
Year: 2009
Journal: J Exp Med
Title: Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.
Volume: 206
Issue: 1
Pages: 89-97
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Publication
20362473 | J:160755
First Author: Wang L
Year: 2010
Journal: Immunity
Title: Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.
Volume: 32
Issue: 4
Pages: 518-30
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Publication
27032818 | J:235781
 
First Author: Németh T
Year: 2016
Journal: Nat Commun
Title: Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.
Volume: 7
Pages: 11004
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Publication
31626642 | J:283635
First Author: Puñal VM
Year: 2019
Journal: PLoS Biol
Title: Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia.
Volume: 17
Issue: 10
Pages: e3000492
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Publication
11389024 | J:69964
First Author: Wu Y
Year: 2001
Journal: Blood
Title: Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling.
Volume: 97
Issue: 12
Pages: 3836-45
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Publication
10872802 | J:62510
First Author: Iseki M
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins.
Volume: 272
Issue: 1
Pages: 45-54
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Publication
9208839 | J:41170
First Author: Wiest DL
Year: 1997
Journal: Immunity
Title: A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development.
Volume: 6
Issue: 6
Pages: 663-71
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Publication
28424516 | J:248729
First Author: Chen J
Year: 2017
Journal: Nature
Title: SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.
Volume: 544
Issue: 7651
Pages: 493-497
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Publication
21474346 | J:171355
First Author: Kool M
Year: 2011
Journal: Immunity
Title: An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma.
Volume: 34
Issue: 4
Pages: 527-40
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Publication
31169521 | J:295265
First Author: Miyabe C
Year: 2019
Journal: J Clin Invest
Title: Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis.
Volume: 129
Issue: 9
Pages: 3610-3624
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Publication
26453377 | J:233863
First Author: Yi T
Year: 2015
Journal: Immunity
Title: Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses.
Volume: 43
Issue: 4
Pages: 764-75
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Publication
21257963 | J:169412
First Author: Boyle KB
Year: 2011
Journal: J Immunol
Title: Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.
Volume: 186
Issue: 5
Pages: 2978-89
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Publication
30510167 | J:287363
First Author: Briard B
Year: 2019
Journal: Nat Microbiol
Title: Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
Volume: 4
Issue: 2
Pages: 316-327
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Publication
33619517 | J:307823
First Author: Hoover C
Year: 2021
Journal: Blood
Title: Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin.
Volume: 137
Issue: 20
Pages: 2756-2769
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Publication
36343752 | J:331895
 
First Author: Zengeler KE
Year: 2022
Journal: Brain Behav Immun
Title: SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology.
Volume: 108
Pages: 80-97
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Publication
15254900 | J:91730
First Author: Verma-Kurvari S
Year: 2004
Journal: Dev Dyn
Title: Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.
Volume: 230
Issue: 4
Pages: 660-5
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Publication
19501082 | J:152865
First Author: Georgas K
Year: 2009
Journal: Dev Biol
Title: Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.
Volume: 332
Issue: 2
Pages: 273-86
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Publication
32027825 | J:284925
     
First Author: Luo L
Year: 2020
Journal: Neuron
Title: Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.
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Publication
28489004 | J:259186
   
First Author: Heng X
Year: 2017
Journal: Elife
Title: Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.
Volume: 6
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
18369315 | -
First Author: Kulathu Y
Year: 2008
Journal: EMBO J
Title: The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.
Volume: 27
Issue: 9
Pages: 1333-44
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Protein
P48025
Organism: Mus musculus/domesticus
Length: 629  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 174
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 174
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UniProt Feature
UniProt Feature
Begin: 183
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 183
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UniProt Feature
UniProt Feature
Begin: 446
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 446
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UniProt Feature
UniProt Feature
Begin: 189
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 189
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UniProt Feature
UniProt Feature
Begin: 178
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 178
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UniProt Feature
UniProt Feature
Begin: 96
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 96
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UniProt Feature
UniProt Feature
Begin: 84
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 84
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UniProt Feature
UniProt Feature
Begin: 72
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 72
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UniProt Feature
UniProt Feature
Begin: 1
Description: Tyrosine-protein kinase SYK
Type: chain
End: 629
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UniProt Feature
UniProt Feature
Begin: 658
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 658
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UniProt Feature
UniProt Feature
Begin: 460
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 460
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UniProt Feature
UniProt Feature
Begin: 420
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 420
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UniProt Feature
UniProt Feature
Begin: 445
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 445
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UniProt Feature
UniProt Feature
Begin: 675
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 675
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UniProt Feature
UniProt Feature
Begin: 662
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 662
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UniProt Feature
UniProt Feature
Begin: 771
Description: Phosphotyrosine; by SYK
Type: modified residue
End: 771
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Publication
7513017 | -
First Author: Kurosaki T
Year: 1994
Journal: J Exp Med
Title: Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling.
Volume: 179
Issue: 5
Pages: 1725-9
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Publication
7538118 | -
First Author: Rowley RB
Year: 1995
Journal: J Biol Chem
Title: Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation.
Volume: 270
Issue: 19
Pages: 11590-4
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UniProt Feature
UniProt Feature
Begin: 551
Description: Phosphotyrosine; by LYN and SYK
Type: modified residue
End: 551
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UniProt Feature
UniProt Feature
Begin: 388
Description: Phosphotyrosine; by SYK and FES
Type: modified residue
End: 388
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UniProt Feature
UniProt Feature
Begin: 405
Description: Phosphotyrosine; by SYK and FES
Type: modified residue
End: 405
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Publication
12077122 | -
First Author: Hong JJ
Year: 2002
Journal: J Biol Chem
Title: Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase.
Volume: 277
Issue: 35
Pages: 31703-14
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Publication
19696895 | J:162910
First Author: Shio MT
Year: 2009
Journal: PLoS Pathog
Title: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Volume: 5
Issue: 8
Pages: e1000559
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Publication
21123826 | J:170367
First Author: Pearce G
Year: 2011
Journal: Blood
Title: SYK regulates B-cell migration by phosphorylation of the F-actin interacting protein SWAP-70.
Volume: 117
Issue: 5
Pages: 1574-84
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Publication
26870803 | J:295721
First Author: Ghosh S
Year: 2015
Journal: EBioMedicine
Title: Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.
Volume: 2
Issue: 11
Pages: 1785-98
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Publication
15467722 | J:93523
First Author: Tassiulas I
Year: 2004
Journal: Nat Immunol
Title: Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors.
Volume: 5
Issue: 11
Pages: 1181-9
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Strain
MGI:4418908 | B6;129-Syk<tm1Paw> Tg(IghelMD4)4Ccg/AnuApb
Attribute String: targeted mutation, transgenic, mutant stock
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UniProt Feature
UniProt Feature
Begin: 783
Description: Phosphotyrosine; by ITK, SYK and TXK
Type: modified residue
End: 783
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Publication
23299888 | J:221238
 
First Author: Romero-Camarero I
Year: 2013
Journal: Nat Commun
Title: Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation.
Volume: 4
Pages: 1338
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Publication
20153221 | J:157914
First Author: Letellier E
Year: 2010
Journal: Immunity
Title: CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site.
Volume: 32
Issue: 2
Pages: 240-52
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Publication
28399410 | J:242493
First Author: Mohr S
Year: 2017
Journal: Cancer Cell
Title: Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.
Volume: 31
Issue: 4
Pages: 549-562.e11
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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