Type |
Details |
Score |
Publication |
First Author: |
Unterholzner L |
Year: |
2010 |
Journal: |
Nat Immunol |
Title: |
IFI16 is an innate immune sensor for intracellular DNA. |
Volume: |
11 |
Issue: |
11 |
Pages: |
997-1004 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamran N |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Toll-like receptor ligands induce expression of the costimulatory molecule CD155 on antigen-presenting cells. |
Volume: |
8 |
Issue: |
1 |
Pages: |
e54406 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ono C |
Year: |
2014 |
Journal: |
J Virol |
Title: |
Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells. |
Volume: |
88 |
Issue: |
4 |
Pages: |
2157-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panda S |
Year: |
2015 |
Journal: |
Immunity |
Title: |
Deubiquitinase MYSM1 Regulates Innate Immunity through Inactivation of TRAF3 and TRAF6 Complexes. |
Volume: |
43 |
Issue: |
4 |
Pages: |
647-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Piersma SJ |
Year: |
2020 |
Journal: |
Elife |
Title: |
Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li N |
Year: |
2024 |
Journal: |
Viruses |
Title: |
Redundancy in Innate Immune Pathways That Promote CD8(+) T-Cell Responses in AAV1 Muscle Gene Transfer. |
Volume: |
16 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marichal T |
Year: |
2011 |
Journal: |
Nat Med |
Title: |
DNA released from dying host cells mediates aluminum adjuvant activity. |
Volume: |
17 |
Issue: |
8 |
Pages: |
996-1002 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu TT |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner. |
Volume: |
196 |
Issue: |
12 |
Pages: |
5101-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li S |
Year: |
2011 |
Journal: |
Immunity |
Title: |
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. |
Volume: |
35 |
Issue: |
3 |
Pages: |
426-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayashi M |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine. |
Volume: |
6 |
|
Pages: |
29165 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bürckstümmer T |
Year: |
2009 |
Journal: |
Nat Immunol |
Title: |
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. |
Volume: |
10 |
Issue: |
3 |
Pages: |
266-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuriakose T |
Year: |
2016 |
Journal: |
Sci Immunol |
Title: |
ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways. |
Volume: |
1 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Onishi M |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen. |
Volume: |
194 |
Issue: |
6 |
Pages: |
2673-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang D |
Year: |
2020 |
Journal: |
Adv Sci (Weinh) |
Title: |
Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors. |
Volume: |
7 |
Issue: |
23 |
Pages: |
2002117 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nedomova M |
Year: |
2024 |
Journal: |
iScience |
Title: |
DDI2 protease controls embryonic development and inflammation via TCF11/NRF1. |
Volume: |
27 |
Issue: |
10 |
Pages: |
110893 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kenney-Hunt JP |
Year: |
2006 |
Journal: |
Mamm Genome |
Title: |
Quantitative trait loci for body size components in mice. |
Volume: |
17 |
Issue: |
6 |
Pages: |
526-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Taconic |
Year: |
2006 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from Taconic website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hoffman BG |
Year: |
2008 |
Journal: |
Genome Biol |
Title: |
Identification of transcripts with enriched expression in the developing and adult pancreas. |
Volume: |
9 |
Issue: |
6 |
Pages: |
R99 |
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Visel A |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
Volume: |
32 |
Issue: |
Database issue |
Pages: |
D552-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
729
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
TANK-binding kinase 1; endonuclease-mediated mutation 1, Pinglong Xu |
Allele Type: |
Endonuclease-mediated |
|
|
•
•
•
•
•
|
Allele |
Name: |
TANK-binding kinase 1; endonuclease-mediated mutation 2, Pinglong Xu |
Allele Type: |
Endonuclease-mediated |
|
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
418 |
Description: |
Phosphoserine; by TBK1 |
Type: |
modified residue |
End: |
418 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
157 |
Description: |
Phosphoserine; by TBK1 |
Type: |
modified residue |
End: |
157 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
379 |
Description: |
Phosphoserine; by TBK1 |
Type: |
modified residue |
End: |
379 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
794 |
Description: |
Phosphothreonine; by TBK1 |
Type: |
modified residue |
End: |
794 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Serine/threonine-protein kinase TBK1 |
Type: |
chain |
End: |
729 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
357 |
Description: |
Phosphoserine; by TBK1 |
Type: |
modified residue |
End: |
357 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
365 |
Description: |
Phosphoserine; by TBK1 |
Type: |
modified residue |
End: |
365 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
121
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
108
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
HDAC6 Mediates Poly (I:C)-Induced TBK1 and Akt Phosphorylation in Macrophages. |
Volume: |
11 |
|
Pages: |
1776 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reilly SM |
Year: |
2013 |
Journal: |
Nat Med |
Title: |
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. |
Volume: |
19 |
Issue: |
3 |
Pages: |
313-21 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
177 |
Description: |
Phosphoserine; by TBK1 and PKC/PRKCZ |
Type: |
modified residue |
End: |
177 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
431 |
Description: |
Phosphoserine; by TBK1 and IKKE |
Type: |
modified residue |
End: |
431 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
405 |
Description: |
Phosphoserine; by ULK1 and TBK1 |
Type: |
modified residue |
End: |
405 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goncalves A |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Functional dissection of the TBK1 molecular network. |
Volume: |
6 |
Issue: |
9 |
Pages: |
e23971 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sarraf SA |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. |
Volume: |
29 |
Issue: |
1 |
Pages: |
225-235.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan Z |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation. |
Volume: |
36 |
Issue: |
12 |
Pages: |
109731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin Y |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
PTK2B promotes TBK1 and STING oligomerization and enhances the STING-TBK1 signaling. |
Volume: |
14 |
Issue: |
1 |
Pages: |
7567 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li X |
Year: |
2016 |
Journal: |
Nat Immunol |
Title: |
Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity. |
Volume: |
17 |
Issue: |
7 |
Pages: |
806-15 |
|
•
•
•
•
•
|
Allele |
Name: |
TBK1 binding protein 1; wild type |
Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Deng M |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination. |
Volume: |
11 |
Issue: |
1 |
Pages: |
2193 |
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Publication |
First Author: |
Zhang K |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation. |
Volume: |
26 |
Issue: |
5 |
Pages: |
1258-1272.e4 |
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Publication |
First Author: |
Bussi C |
Year: |
2018 |
Journal: |
J Cell Sci |
Title: |
Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells. |
Volume: |
131 |
Issue: |
23 |
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Publication |
First Author: |
Deng T |
Year: |
2014 |
Journal: |
Cancer Res |
Title: |
shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer. |
Volume: |
74 |
Issue: |
7 |
Pages: |
2119-30 |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|