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Search results 301 to 400 out of 612 for Tbk1

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Type Details Score
Publication
21903422 | J:176666
First Author: Li S
Year: 2011
Journal: Immunity
Title: Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.
Volume: 35
Issue: 3
Pages: 426-40
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Publication
27183626 | J:240213
First Author: Liu TT
Year: 2016
Journal: J Immunol
Title: LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.
Volume: 196
Issue: 12
Pages: 5101-11
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Publication
27374884 | J:291655
 
First Author: Hayashi M
Year: 2016
Journal: Sci Rep
Title: RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine.
Volume: 6
Pages: 29165
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Publication
19158679 | J:145965
First Author: Bürckstümmer T
Year: 2009
Journal: Nat Immunol
Title: An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.
Volume: 10
Issue: 3
Pages: 266-72
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Publication
27917412 | J:290369
 
First Author: Kuriakose T
Year: 2016
Journal: Sci Immunol
Title: ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.
Volume: 1
Issue: 2
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Publication
25681338 | J:274041
First Author: Onishi M
Year: 2015
Journal: J Immunol
Title: Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Volume: 194
Issue: 6
Pages: 2673-82
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Publication
33304758 | J:326486
First Author: Zhang D
Year: 2020
Journal: Adv Sci (Weinh)
Title: Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors.
Volume: 7
Issue: 23
Pages: 2002117
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
16783635 | J:109795
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Protein
Q9WUN2
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: false
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Allele
Tbk1<em1Plxu> | MGI:7663909
 
Name: TANK-binding kinase 1; endonuclease-mediated mutation 1, Pinglong Xu
Allele Type: Endonuclease-mediated
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Allele
Tbk1<em2Plxu> | MGI:7663910
 
Name: TANK-binding kinase 1; endonuclease-mediated mutation 1, Pinglong Xu
Allele Type: Endonuclease-mediated
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GO Term
GO:0039723 | symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity
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Gene
108700785 | tbkbp1.L
Type: gene
Organism: frog, African clawed
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Gene
108702504 | tbkbp1.S
Type: gene
Organism: frog, African clawed
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UniProt Feature
UniProt Feature
Begin: 418
Description: Phosphoserine; by TBK1
Type: modified residue
End: 418
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UniProt Feature
UniProt Feature
Begin: 157
Description: Phosphoserine; by TBK1
Type: modified residue
End: 157
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UniProt Feature
UniProt Feature
Begin: 379
Description: Phosphoserine; by TBK1
Type: modified residue
End: 379
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UniProt Feature
UniProt Feature
Begin: 794
Description: Phosphothreonine; by TBK1
Type: modified residue
End: 794
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase TBK1
Type: chain
End: 729
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UniProt Feature
UniProt Feature
Begin: 357
Description: Phosphoserine; by TBK1
Type: modified residue
End: 357
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UniProt Feature
UniProt Feature
Begin: 365
Description: Phosphoserine; by TBK1
Type: modified residue
End: 365
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Protein
A0A1W2P6W7
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: false
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Protein
A0A1W2P835
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Publication
32849638 | J:308200
 
First Author: Wang Y
Year: 2020
Journal: Front Immunol
Title: HDAC6 Mediates Poly (I:C)-Induced TBK1 and Akt Phosphorylation in Macrophages.
Volume: 11
Pages: 1776
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Publication
23396211 | -
First Author: Reilly SM
Year: 2013
Journal: Nat Med
Title: An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice.
Volume: 19
Issue: 3
Pages: 313-21
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UniProt Feature
UniProt Feature
Begin: 177
Description: Phosphoserine; by TBK1 and PKC/PRKCZ
Type: modified residue
End: 177
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UniProt Feature
UniProt Feature
Begin: 431
Description: Phosphoserine; by TBK1 and IKKE
Type: modified residue
End: 431
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UniProt Feature
UniProt Feature
Begin: 405
Description: Phosphoserine; by ULK1 and TBK1
Type: modified residue
End: 405
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Publication
21931631 | -
First Author: Goncalves A
Year: 2011
Journal: PLoS One
Title: Functional dissection of the TBK1 molecular network.
Volume: 6
Issue: 9
Pages: e23971
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Publication
31577952 | J:337054
First Author: Sarraf SA
Year: 2019
Journal: Cell Rep
Title: PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis.
Volume: 29
Issue: 1
Pages: 225-235.e5
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Publication
37989995 | J:342961
First Author: Lin Y
Year: 2023
Journal: Nat Commun
Title: PTK2B promotes TBK1 and STING oligomerization and enhances the STING-TBK1 signaling.
Volume: 14
Issue: 1
Pages: 7567
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Publication
34551290 | J:323833
First Author: Yan Z
Year: 2021
Journal: Cell Rep
Title: The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation.
Volume: 36
Issue: 12
Pages: 109731
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Publication
27240213 | J:260234
First Author: Li X
Year: 2016
Journal: Nat Immunol
Title: Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity.
Volume: 17
Issue: 7
Pages: 806-15
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Allele
Tbkbp1<+> | MGI:3608346
 
Name: TBK1 binding protein 1; wild type
Allele Type: Not Specified
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Publication
30699353 | J:289833
First Author: Zhang K
Year: 2019
Journal: Cell Rep
Title: DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
Volume: 26
Issue: 5
Pages: 1258-1272.e4
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Publication
32366851 | J:292816
First Author: Deng M
Year: 2020
Journal: Nat Commun
Title: TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination.
Volume: 11
Issue: 1
Pages: 2193
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Publication
30404831 | J:269341
 
First Author: Bussi C
Year: 2018
Journal: J Cell Sci
Title: Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells.
Volume: 131
Issue: 23
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Publication
24487029 | J:208323
First Author: Deng T
Year: 2014
Journal: Cancer Res
Title: shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer.
Volume: 74
Issue: 7
Pages: 2119-30
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Protein Coding Gene
MGP_CAROLIEiJ_G0017049 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019025 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018993 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018963 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018966 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018780 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920424 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018333 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018751 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019458 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018179 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017895 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692044
Age: postnatal adult
Image: MRC Harwell_1311991
Specimen Label: MRC Harwell_1311991
Detected: true
Specimen Num: 5
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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