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Search results 301 to 396 out of 396 for Tnfrsf19

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3027633
Age: embryonic day 12.0
Image: 3C
Note: Expression is in the head tissue immediately rostral to the eye.
Specimen Label: 3C
Detected: true
Specimen Num: 10
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_01
Specimen Label: euxassay_000124_01
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_02
Specimen Label: euxassay_000124_02
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_03
Specimen Label: euxassay_000124_03
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_04
Specimen Label: euxassay_000124_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_08
Specimen Label: euxassay_000124_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_18
Specimen Label: euxassay_000124_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_21
Specimen Label: euxassay_000124_21
Detected: true
Specimen Num: 21
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_22
Specimen Label: euxassay_000124_22
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_23
Specimen Label: euxassay_000124_23
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_11
Specimen Label: euxassay_000124_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:495634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828845
Age: embryonic day 14.5
Image: euxassay_000124_15
Specimen Label: euxassay_000124_15
Detected: true
Specimen Num: 15
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3027633
Age: embryonic day 14.0
Image: 1D
Specimen Label: 1D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3027633
Age: embryonic day 15.0
Image: 1E
Specimen Label: 1E
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3674020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3027633
Age: embryonic day 12.0
Image: 3I
Specimen Label: 3I
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674225
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:3027633
Age: embryonic day 17.0
Image: 1F
Specimen Label: 1F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3808522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3027633
Age: embryonic day 14.0
Image: 1D
Specimen Label: 1D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3808523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3027633
Age: embryonic day 15.0
Image: 1E
Specimen Label: 1E
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3808525
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:3027633
Age: embryonic day 17.0
Image: 1F
Note: Expression is mainly in the buccal inner enamel epithelium.
Specimen Label: 1F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3808122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3027633
Age: embryonic day 14.0
Image: 1D
Specimen Label: 1D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3027599
Assay Type: RNA in situ
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3808123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3027633
Age: embryonic day 15.0
Image: 1E
Specimen Label: 1E
Detected: true
Specimen Num: 5
•
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Publication
15694321 | J:97334
First Author: Park JB
Year: 2005
Journal: Neuron
Title: A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors.
Volume: 45
Issue: 3
Pages: 345-51
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Publication
29311336 | J:254891
First Author: Basak O
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy.
Volume: 115
Issue: 4
Pages: E610-E619
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Publication
17470639 | J:134726
First Author: Venkatesh K
Year: 2007
Journal: J Cell Biol
Title: Molecular dissection of the myelin-associated glycoprotein receptor complex reveals cell type-specific mechanisms for neurite outgrowth inhibition.
Volume: 177
Issue: 3
Pages: 393-9
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Publication
38565145 | J:348841
First Author: Grommisch D
Year: 2024
Journal: Dev Cell
Title: Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium.
Volume: 59
Issue: 10
Pages: 1269-1283.e6
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Publication
17362907 | J:121341
First Author: Drew CF
Year: 2007
Journal: Dev Biol
Title: The Edar subfamily in feather placode formation.
Volume: 305
Issue: 1
Pages: 232-45
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Publication
24120136 | J:214484
First Author: Stange DE
Year: 2013
Journal: Cell
Title: Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium.
Volume: 155
Issue: 2
Pages: 357-68
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Publication
35523142 | J:329222
First Author: Lee JH
Year: 2022
Journal: Cell Stem Cell
Title: p57Kip2 imposes the reserve stem cell state of gastric chief cells.
Volume: 29
Issue: 5
Pages: 826-839.e9
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Publication
18584774 | J:138614
 
First Author: Morikawa Y
Year: 2008
Journal: Ann N Y Acad Sci
Title: TROY, a novel member of the tumor necrosis factor receptor superfamily in the central nervous system.
Volume: 1126
Pages: A1-10
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Publication
26367446 | J:229415
 
First Author: Liu G
Year: 2015
Journal: Brain Res
Title: Expression of Nogo receptor 1 in microglia during development and following traumatic brain injury.
Volume: 1627
Pages: 41-51
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Publication
12060722 | J:77350
First Author: Naito A
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: TRAF6-deficient mice display hypohidrotic ectodermal dysplasia.
Volume: 99
Issue: 13
Pages: 8766-71
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Publication
14699584 | J:87318
First Author: Ohazama A
Year: 2004
Journal: Dev Dyn
Title: Traf6 is essential for murine tooth cusp morphogenesis.
Volume: 229
Issue: 1
Pages: 131-5
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Publication
14966863 | J:88397
First Author: Hisaoka T
Year: 2004
Journal: Glia
Title: Expression of a member of tumor necrosis factor receptor superfamily, TROY, in the developing olfactory system.
Volume: 45
Issue: 4
Pages: 313-24
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Publication
20093372 | J:161875
First Author: Mathis C
Year: 2010
Journal: Cereb Cortex
Title: Nogo-a regulates neural precursor migration in the embryonic mouse cortex.
Volume: 20
Issue: 10
Pages: 2380-90
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Publication
16820005 | J:112162
First Author: Hisaoka T
Year: 2006
Journal: Eur J Neurosci
Title: Characterization of TROY-expressing cells in the developing and postnatal CNS: the possible role in neuronal and glial cell development.
Volume: 23
Issue: 12
Pages: 3149-60
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Publication
16481354 | J:106549
First Author: Schmidt-Ullrich R
Year: 2006
Journal: Development
Title: NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.
Volume: 133
Issue: 6
Pages: 1045-57
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Publication
37227110 | J:340939
First Author: Deacon E
Year: 2023
Journal: Dev Dyn
Title: β-Catenin in the kidney stroma modulates pathways and genes to regulate kidney development.
Volume: 252
Issue: 9
Pages: 1224-1239
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Publication
24997521 | J:219387
First Author: Ng A
Year: 2014
Journal: Nat Cell Biol
Title: Lgr5 marks stem/progenitor cells in ovary and tubal epithelia.
Volume: 16
Issue: 8
Pages: 745-57
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Publication
12781685 | J:83702
First Author: Buttitta L
Year: 2003
Journal: Dev Biol
Title: Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm.
Volume: 258
Issue: 1
Pages: 91-104
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Publication
25645944 | J:219786
First Author: Naillat F
Year: 2015
Journal: Exp Cell Res
Title: Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.
Volume: 332
Issue: 2
Pages: 163-78
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Publication
32468660 | J:312814
First Author: Fernandez Vallone V
Year: 2020
Journal: EMBO Rep
Title: LGR5 controls extracellular matrix production by stem cells in the developing intestine.
Volume: 21
Issue: 7
Pages: e49224
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Publication
29449449 | J:296648
First Author: Lindström NO
Year: 2018
Journal: J Am Soc Nephrol
Title: Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney.
Volume: 29
Issue: 3
Pages: 806-824
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Publication
17278136 | J:137001
First Author: Akins MR
Year: 2007
Journal: J Comp Neurol
Title: Cadherin expression in the developing mouse olfactory system.
Volume: 501
Issue: 4
Pages: 483-97
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Publication
34391772 | J:314694
First Author: Douchi D
Year: 2021
Journal: Gastroenterology
Title: Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus.
Volume: 161
Issue: 6
Pages: 1907-1923.e26
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Publication
12702649 | J:82802
First Author: Ruiz S
Year: 2003
Journal: Development
Title: Abnormal epidermal differentiation and impaired epithelial-mesenchymal tissue interactions in mice lacking the retinoblastoma relatives p107 and p130.
Volume: 130
Issue: 11
Pages: 2341-53
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Publication
29555813 | J:259848
 
First Author: Chal J
Year: 2018
Journal: Development
Title: Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.
Volume: 145
Issue: 6
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Publication
11239407 | J:74923
First Author: Locksley RM
Year: 2001
Journal: Cell
Title: The TNF and TNF receptor superfamilies: integrating mammalian biology.
Volume: 104
Issue: 4
Pages: 487-501
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Publication
17095659 | J:116164
First Author: Dequéant ML
Year: 2006
Journal: Science
Title: A complex oscillating network of signaling genes underlies the mouse segmentation clock.
Volume: 314
Issue: 5805
Pages: 1595-8
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Publication
16524929 | J:107400
First Author: Laurikkala J
Year: 2006
Journal: Development
Title: p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.
Volume: 133
Issue: 8
Pages: 1553-63
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Publication
22235033 | J:203028
First Author: Hasenpusch-Theil K
Year: 2012
Journal: Cereb Cortex
Title: Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus.
Volume: 22
Issue: 12
Pages: 2878-93
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Publication
16782087 | J:112633
First Author: Jukkola T
Year: 2006
Journal: Dev Biol
Title: FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region.
Volume: 297
Issue: 1
Pages: 141-57
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Publication
28813421 | J:253067
First Author: Sigal M
Year: 2017
Journal: Nature
Title: Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Volume: 548
Issue: 7668
Pages: 451-455
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Publication
21947380 | J:181586
First Author: Hald J
Year: 2012
Journal: Diabetologia
Title: Pancreatic islet and progenitor cell surface markers with cell sorting potential.
Volume: 55
Issue: 1
Pages: 154-65
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
24623448 | -
First Author: Schön S
Year: 2014
Journal: Int J Cancer
Title: β-catenin regulates NF-κB activity via TNFRSF19 in colorectal cancer cells.
Volume: 135
Issue: 8
Pages: 1800-11
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Publication
23699535 | -
First Author: Loftus JC
Year: 2013
Journal: Mol Cancer Res
Title: TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance.
Volume: 11
Issue: 8
Pages: 865-74
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Protein Domain
IPR034047 | TNFRSF19_N
Type: Domain
Description: TNFRSF19 (also known as TAJ; TROY; TRADE; TAJ-alpha) is expressed in progenitor cells of the hippocampus, thalamus, and cerebral cortex and highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells [, ]. It is frequently overexpressed in colorectal cancer cell lines and primary colorectal carcinomas. TNFRSF19 is a beta-catenin target gene, in mesenchymal stem cells, and also activates NF-kappaB signaling, showing that beta-catenin regulates NF-kappaB activity via TNFRSF19. Since Wnt/beta-catenin signaling plays a crucial role in the regulation of colon tissue regeneration and the development of colon tumors, TNFRSF19 may contribute to the development of colorectal tumors []. These findings define a role for death receptors DR6 and TROY in CNS-specific vascular development []. TNFRSF19 has been shown to promote glioblastoma (GBM) survival signaling and therefore targeting it may increase tumor vulnerability and improve therapeutic response in glioblastoma []. It may play an important role in myelin-associated inhibitory factors (MAIFs)-induced inhibition of neurite outgrowth in the postnatal central nervous system (CNS) or on axon regeneration following CNS injury [].This entry represents the N-terminal domain of TNFRSF19. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Allele
Tg(Tnfrsf19-cre/ERT2)1Kori | MGI:5575757
Name: transgene insertion 1, Vladimir Korinek
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Strain
MGI:5575761 | C57BL/6N-Tg(Tnfrsf19-cre/ERT2)1Kori/Ph
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:5575762 | C57BL/6N-Tg(Tnfrsf19-cre/ERT2)1Kori
Attribute String: congenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(Tnfrsf19-cre/ERT2)1Kori/Tg(Tnfrsf19-cre/ERT2)1Kori
Background: C57BL/6N-Tg(Tnfrsf19-cre/ERT2)1Kori
Zygosity: hm
Has Mutant Allele: true
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Protein
Q9JLL3
Organism: Mus musculus/domesticus
Length: 416  
Fragment?: false
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Protein
Q8BUM7
Organism: Mus musculus/domesticus
Length: 416  
Fragment?: false
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Publication
26585400 | J:227252
First Author: Hayakawa Y
Year: 2015
Journal: Cancer Cell
Title: Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.
Volume: 28
Issue: 6
Pages: 800-814
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Publication
9538693 | -
First Author: Naismith JH
Year: 1998
Journal: Trends Biochem Sci
Title: Modularity in the TNF-receptor family.
Volume: 23
Issue: 2
Pages: 74-9
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Publication
11796220 | -
First Author: Bodmer JL
Year: 2002
Journal: Trends Biochem Sci
Title: The molecular architecture of the TNF superfamily.
Volume: 27
Issue: 1
Pages: 19-26
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Publication
8387891 | -
First Author: Banner DW
Year: 1993
Journal: Cell
Title: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume: 73
Issue: 3
Pages: 431-45
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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