| Type |
Details |
Score |
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
555
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
213
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
513
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qian Y |
| Year: |
2007 |
| Journal: |
Nat Immunol |
| Title: |
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. |
| Volume: |
8 |
| Issue: |
3 |
| Pages: |
247-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao K |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response. |
| Volume: |
6 |
|
| Pages: |
23771 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giltiay NV |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
Spontaneous loss of tolerance of autoreactive B cells in Act1-deficient rheumatoid factor transgenic mice. |
| Volume: |
191 |
| Issue: |
5 |
| Pages: |
2155-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lipovsky A |
| Year: |
2021 |
| Journal: |
J Invest Dermatol |
| Title: |
ACT1 Is Required for Murine IL-23-Induced Psoriasiform Inflammation Potentially Independent of E3 Ligase Activity. |
| Volume: |
141 |
| Issue: |
7 |
| Pages: |
1772-1779.e6 |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Peng S |
| Year: |
2015 |
| Journal: |
Clin Exp Immunol |
| Title: |
TRAF3IP3, a novel autophagy up-regulated gene, is involved in marginal zone B lymphocyte development and survival. |
| Volume: |
182 |
| Issue: |
1 |
| Pages: |
57-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giltiay NV |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
The adaptor molecule Act1 regulates BAFF responsiveness and self-reactive B cell selection during transitional B cell maturation. |
| Volume: |
185 |
| Issue: |
1 |
| Pages: |
99-109 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deng M |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
2193 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xin D |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Parkin negatively regulates the antiviral signaling pathway by targeting TRAF3 for degradation. |
| Volume: |
293 |
| Issue: |
31 |
| Pages: |
11996-12010 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Johnson AC |
| Year: |
2012 |
| Journal: |
Eur J Immunol |
| Title: |
Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease. |
| Volume: |
42 |
| Issue: |
7 |
| Pages: |
1695-705 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Claudio E |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation. |
| Volume: |
182 |
| Issue: |
3 |
| Pages: |
1617-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Perez-Chacon G |
| Year: |
2018 |
| Journal: |
Front Immunol |
| Title: |
Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice. |
| Volume: |
9 |
|
| Pages: |
3114 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Y |
| Year: |
2023 |
| Journal: |
PLoS One |
| Title: |
MicroRNA-29b-3p promotes intestinal permeability in IBS-D via targeting TRAF3 to regulate the NF-κB-MLCK signaling pathway. |
| Volume: |
18 |
| Issue: |
7 |
| Pages: |
e0287597 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zou Q |
| Year: |
2015 |
| Journal: |
J Exp Med |
| Title: |
T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi. |
| Volume: |
212 |
| Issue: |
8 |
| Pages: |
1323-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun L |
| Year: |
2020 |
| Journal: |
J Immunol |
| Title: |
IL-10 Dampens an IL-17-Mediated Periodontitis-Associated Inflammatory Network. |
| Volume: |
204 |
| Issue: |
8 |
| Pages: |
2177-2191 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Swaidani S |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
T cell-derived Act1 is necessary for IL-25-mediated Th2 responses and allergic airway inflammation. |
| Volume: |
187 |
| Issue: |
6 |
| Pages: |
3155-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu C |
| Year: |
2009 |
| Journal: |
Sci Signal |
| Title: |
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling. |
| Volume: |
2 |
| Issue: |
92 |
| Pages: |
ra63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Swaidani S |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation. |
| Volume: |
182 |
| Issue: |
3 |
| Pages: |
1631-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ng MH |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
MIP-T3 is a negative regulator of innate type I IFN response. |
| Volume: |
187 |
| Issue: |
12 |
| Pages: |
6473-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Das NA |
| Year: |
2018 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart. |
| Volume: |
121 |
|
| Pages: |
107-123 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation. |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
625
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu X |
| Year: |
2018 |
| Journal: |
J Exp Med |
| Title: |
Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome. |
| Volume: |
215 |
| Issue: |
9 |
| Pages: |
2463-2476 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang Z |
| Year: |
2010 |
| Journal: |
Immunity |
| Title: |
Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis. |
| Volume: |
32 |
| Issue: |
3 |
| Pages: |
414-25 |
|
•
•
•
•
•
|
| Allele |
| Name: |
amnionless |
| Allele Type: |
Transgenic |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang Z |
| Year: |
2012 |
| Journal: |
Immunity |
| Title: |
Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population. |
| Volume: |
36 |
| Issue: |
5 |
| Pages: |
821-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barin JG |
| Year: |
2012 |
| Journal: |
Eur J Immunol |
| Title: |
Macrophages participate in IL-17-mediated inflammation. |
| Volume: |
42 |
| Issue: |
3 |
| Pages: |
726-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ha HL |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms. |
| Volume: |
111 |
| Issue: |
33 |
| Pages: |
E3422-31 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang X |
| Year: |
2020 |
| Journal: |
Cell Mol Immunol |
| Title: |
TRAF3IP3 at the trans-Golgi network regulates NKT2 maturation via the MEK/ERK signaling pathway. |
| Volume: |
17 |
| Issue: |
4 |
| Pages: |
395-406 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426840 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828887 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_014103_09 |
|
| Specimen Label: |
euxassay_014103_09 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426840 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828887 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_014103_10 |
|
| Specimen Label: |
euxassay_014103_10 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426840 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828887 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_014103_11 |
|
| Specimen Label: |
euxassay_014103_11 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426840 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828887 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_014103_12 |
|
| Specimen Label: |
euxassay_014103_12 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426840 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828887 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_014103_14 |
|
| Specimen Label: |
euxassay_014103_14 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426840 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828887 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_014103_15 |
|
| Specimen Label: |
euxassay_014103_15 |
| Detected: |
true |
| Specimen Num: |
6 |
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