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Search results 301 to 400 out of 499 for Trem2

0.03s
Type Details Score
GXD Expression    
Probe: MGI:7616917
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7616919
Age: embryonic day 16.5
Specimen Label: 6A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1723859
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1745423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828900
Age: embryonic day 14.5
Image: euxassay_006762_02
Specimen Label: euxassay_006762_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1723859
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1745423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828900
Age: embryonic day 14.5
Image: euxassay_006762_04
Specimen Label: euxassay_006762_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1723859
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1745423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828900
Age: embryonic day 14.5
Image: euxassay_006762_07
Specimen Label: euxassay_006762_07
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5001727
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542281
Age: embryonic day 15.5
Image: GUDMAP:11546
Specimen Label: GUDMAP:11546
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001727
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542281
Age: embryonic day 15.5
Image: GUDMAP:11561
Specimen Label: GUDMAP:11561
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001727
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542281
Age: embryonic day 15.5
Image: GUDMAP:11561
Specimen Label: GUDMAP:11561
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001727
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542281
Age: embryonic day 15.5
Image: GUDMAP:11546
Specimen Label: GUDMAP:11546
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001727
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542281
Age: embryonic day 15.5
Image: GUDMAP:11561
Specimen Label: GUDMAP:11561
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001727
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542281
Age: embryonic day 15.5
Image: GUDMAP:11561
Specimen Label: GUDMAP:11561
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1723859
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828900
Age: embryonic day 14.5
Image: euxassay_006762_14
Specimen Label: euxassay_006762_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1723859
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828900
Age: embryonic day 14.5
Image: euxassay_006762_15
Specimen Label: euxassay_006762_15
Detected: true
Specimen Num: 15
Publication
First Author: Henn D
Year: 2021
Journal: Sci Adv
Title: Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2(+) macrophages.
Volume: 7
Issue: 49
Pages: eabi4528
Publication
First Author: Puntambekar SS
Year: 2022
Journal: Mol Neurodegener
Title: CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 47
Publication
First Author: Whittaker GC
Year: 2010
Journal: J Biol Chem
Title: The linker for activation of B cells (LAB)/non-T cell activation linker (NTAL) regulates triggering receptor expressed on myeloid cells (TREM)-2 signaling and macrophage inflammatory responses independently of the linker for activation of T cells.
Volume: 285
Issue: 5
Pages: 2976-85
Publication
First Author: Hommes TJ
Year: 2015
Journal: Am J Respir Cell Mol Biol
Title: Role of triggering receptor expressed on myeloid cells-1/3 in Klebsiella-derived pneumosepsis.
Volume: 53
Issue: 5
Pages: 647-55
Publication
First Author: Sharif O
Year: 2014
Journal: PLoS Pathog
Title: The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.
Volume: 10
Issue: 6
Pages: e1004167
Publication  
First Author: Wu K
Year: 2023
Journal: Brain Behav Immun
Title: The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis.
Volume: 112
Pages: 96-117
Publication
First Author: Quan DN
Year: 2008
Journal: Mucosal Immunol
Title: TREM-2 binds to lipooligosaccharides of Neisseria gonorrhoeae and is expressed on reproductive tract epithelial cells.
Volume: 1
Issue: 3
Pages: 229-38
Publication
First Author: Daws MR
Year: 2003
Journal: J Immunol
Title: Pattern recognition by TREM-2: binding of anionic ligands.
Volume: 171
Issue: 2
Pages: 594-9
Publication
First Author: Hamerman JA
Year: 2006
Journal: J Immunol
Title: Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.
Volume: 177
Issue: 4
Pages: 2051-5
Publication
First Author: Yoon SH
Year: 2012
Journal: J Biol Chem
Title: TLT-1s, alternative transcripts of triggering receptor expressed on myeloid cell-like transcript-1 (TLT-1), Inhibits the triggering receptor expressed on myeloid cell-2 (TREM-2)-mediated signaling pathway during osteoclastogenesis.
Volume: 287
Issue: 35
Pages: 29620-6
Publication
First Author: Sun R
Year: 2024
Journal: Nat Commun
Title: Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages.
Volume: 15
Issue: 1
Pages: 966
Publication
First Author: Bouchon A
Year: 2000
Journal: J Immunol
Title: Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes.
Volume: 164
Issue: 10
Pages: 4991-5
Publication
First Author: Helming L
Year: 2008
Journal: Sci Signal
Title: Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.
Volume: 1
Issue: 43
Pages: ra11
Publication
First Author: Hemmi H
Year: 2009
Journal: J Immunol
Title: A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells.
Volume: 182
Issue: 3
Pages: 1278-86
Publication
First Author: Kim Y
Year: 2005
Journal: J Biol Chem
Title: Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis.
Volume: 280
Issue: 38
Pages: 32905-13
Publication
First Author: Ito H
Year: 2012
Journal: Eur J Immunol
Title: TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells.
Volume: 42
Issue: 1
Pages: 176-85
Publication
First Author: Sziraki A
Year: 2023
Journal: Nat Genet
Title: A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains.
Volume: 55
Issue: 12
Pages: 2104-2116
Publication
First Author: Pandey RS
Year: 2024
Journal: Alzheimers Dement
Title: Metabolomics profiling reveals distinct, sex-specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: 3987-4001
Publication
First Author: Preuss C
Year: 2020
Journal: Mol Neurodegener
Title: A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 67
Publication
First Author: Xiang X
Year: 2021
Journal: Sci Transl Med
Title: Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
Volume: 13
Issue: 615
Pages: eabe5640
Publication
First Author: Pandey RS
Year: 2023
Journal: BMC Genomics
Title: Differential splicing of neuronal genes in a Trem2*R47H mouse model mimics alterations associated with Alzheimer's disease.
Volume: 24
Issue: 1
Pages: 172
Publication  
First Author: Kotredes KP
Year: 2021
Journal: Front Aging Neurosci
Title: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.
Volume: 13
Pages: 735524
Publication
First Author: Chung DH
Year: 2002
Journal: Eur J Immunol
Title: Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17.
Volume: 32
Issue: 1
Pages: 59-66
Publication
First Author: Takegahara N
Year: 2006
Journal: Nat Cell Biol
Title: Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis.
Volume: 8
Issue: 6
Pages: 615-22
Publication
First Author: Kaya T
Year: 2022
Journal: Nat Neurosci
Title: CD8(+) T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging.
Volume: 25
Issue: 11
Pages: 1446-1457
Publication
First Author: Turnbull IR
Year: 2006
Journal: J Immunol
Title: Cutting edge: TREM-2 attenuates macrophage activation.
Volume: 177
Issue: 6
Pages: 3520-4
Publication
First Author: McAlpine CS
Year: 2021
Journal: Nature
Title: Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease.
Volume: 595
Issue: 7869
Pages: 701-706
Publication
First Author: Eyo UB
Year: 2018
Journal: Cell Rep
Title: P2Y12R-Dependent Translocation Mechanisms Gate the Changing Microglial Landscape.
Volume: 23
Issue: 4
Pages: 959-966
Publication
First Author: Eyo UB
Year: 2021
Journal: Cell Rep
Title: Microglia provide structural resolution to injured dendrites after severe seizures.
Volume: 35
Issue: 5
Pages: 109080
Publication  
First Author: Wellman SM
Year: 2023
Journal: J Neural Eng
Title: Aberrant accumulation of age- and disease-associated factors following neural probe implantation in a mouse model of Alzheimer's disease.
Volume: 20
Issue: 4
Publication
First Author: Tsai AP
Year: 2023
Journal: Immunity
Title: Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease.
Volume: 56
Issue: 9
Pages: 2121-2136.e6
Publication
First Author: Bocharova OV
Year: 2023
Journal: Brain Pathol
Title: Aβ plaques do not protect against HSV-1 infection in a mouse model of familial Alzheimer's disease, and HSV-1 does not induce Aβ pathology in a model of late onset Alzheimer's disease.
Volume: 33
Issue: 1
Pages: e13116
Publication
First Author: Kotredes KP
Year: 2024
Journal: Alzheimers Dement
Title: Characterizing molecular and synaptic signatures in mouse models of late-onset Alzheimer's disease independent of amyloid and tau pathology.
Volume: 20
Issue: 6
Pages: 4126-4146
Publication  
First Author: Chen Y
Year: 2019
Journal: J Neuroimmunol
Title: Oxymatrine can attenuate pathological deficits of Alzheimer's disease mice through regulation of neuroinflammation.
Volume: 334
Pages: 576978
Publication
First Author: Wakselman S
Year: 2008
Journal: J Neurosci
Title: Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor.
Volume: 28
Issue: 32
Pages: 8138-43
Publication    
First Author: Burns JC
Year: 2020
Journal: Elife
Title: Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain.
Volume: 9
Publication
First Author: Wu K
Year: 2015
Journal: J Exp Med
Title: TREM-2 promotes macrophage survival and lung disease after respiratory viral infection.
Volume: 212
Issue: 5
Pages: 681-97
Publication
First Author: Kaji S
Year: 2024
Journal: Immunity
Title: Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Volume: 57
Issue: 11
Pages: 2651-2668.e12
Publication
First Author: Safaiyan S
Year: 2021
Journal: Neuron
Title: White matter aging drives microglial diversity.
Volume: 109
Issue: 7
Pages: 1100-1117.e10
Publication
First Author: Barrow AD
Year: 2011
Journal: J Clin Invest
Title: OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice.
Volume: 121
Issue: 9
Pages: 3505-16
Publication    
First Author: Park MD
Year: 2024
Journal: Science
Title: Hematopoietic aging promotes cancer by fueling IL-1⍺-driven emergency myelopoiesis.
Pages: eadn0327
Publication
First Author: Terme M
Year: 2004
Journal: J Immunol
Title: IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules.
Volume: 172
Issue: 10
Pages: 5957-66
Publication  
First Author: Oblak AL
Year: 2022
Journal: Front Aging Neurosci
Title: Plcg2(M28L) Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.
Volume: 14
Pages: 886575
Publication
First Author: Hayashi M
Year: 2012
Journal: Nature
Title: Osteoprotection by semaphorin 3A.
Volume: 485
Issue: 7396
Pages: 69-74
Publication
First Author: Wang ECE
Year: 2019
Journal: Cell Stem Cell
Title: A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth.
Volume: 24
Issue: 4
Pages: 654-669.e6
Publication
First Author: Sasner M
Year: 2024
Journal: Alzheimers Dement
Title: In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Volume: 20
Issue: 7
Pages: 4970-4984
Publication
First Author: Li Q
Year: 2019
Journal: Neuron
Title: Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing.
Volume: 101
Issue: 2
Pages: 207-223.e10
Publication
First Author: Ikuta K
Year: 2019
Journal: Gut
Title: Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice.
Volume: 68
Issue: 5
Pages: 882-892
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
Publication
First Author: Loo L
Year: 2019
Journal: Nat Commun
Title: Single-cell transcriptomic analysis of mouse neocortical development.
Volume: 10
Issue: 1
Pages: 134
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Allele
Name: triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 3, Benedikt Wefers
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
Allele
Name: triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 2, MODEL-AD Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
Allele
Name: triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 1, Guojun Bu
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
Allele
Name: triggering receptor expressed on myeloid cells 2; targeted mutation 1.1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Humanized sequence