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Search results 301 to 384 out of 384 for Trf

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Type Details Score
Publication
32044375 | J:287735
 
First Author: Mariani NAP
Year: 2020
Journal: Mol Cell Endocrinol
Title: Epididymal protease inhibitor (EPPIN) is a protein hub for seminal vesicle-secreted protein SVS2 binding in mouse spermatozoa.
Volume: 506
Pages: 110754
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Protein Coding Gene
MGI:1929648 | Med20
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
1280258 | J:81269
First Author: Chiesa G
Year: 1992
Journal: J Biol Chem
Title: Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a).
Volume: 267
Issue: 34
Pages: 24369-74
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Publication
1465128 | J:127053
First Author: Lawn RM
Year: 1992
Journal: Nature
Title: Atherogenesis in transgenic mice expressing human apolipoprotein(a)
Volume: 360
Issue: 6405
Pages: 670-2
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Publication
8940144 | J:37155
First Author: Lawn RM
Year: 1996
Journal: J Biol Chem
Title: Feedback mechanism of focal vascular lesion formation in transgenic apolipoprotein(a) mice.
Volume: 271
Issue: 49
Pages: 31367-71
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Allele
Tg(Trf-EGFP)IF181Gsat | MGI:4847506
Name: transgene insertion IF181, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Publication
30962164 | J:349642
First Author: Esquivel RN
Year: 2019
Journal: Mol Ther
Title: In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus.
Volume: 27
Issue: 5
Pages: 974-985
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Publication
36202799 | J:335978
First Author: Parzych EM
Year: 2022
Journal: Nat Commun
Title: DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Volume: 13
Issue: 1
Pages: 5886
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Publication
35090597 | J:335933
First Author: Konrath KM
Year: 2022
Journal: Cell Rep
Title: Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection.
Volume: 38
Issue: 5
Pages: 110318
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Strain
MGI:5003833 | STOCK Tg(Trf-EGFP)IF181Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
9770530 | J:108651
First Author: Lou XJ
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice.
Volume: 95
Issue: 21
Pages: 12591-5
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Publication
3816991 | J:12738
First Author: Oh YS
Year: 1987
Journal: Jikken Dobutsu
Title: Linkage of faded gene (fe) to chromosome 6 of the mouse.
Volume: 36
Issue: 1
Pages: 73-7
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HT Experiment
E-GEOD-13062 | The effects of temporally restricted feeding on hepatic gene expression of Cry1, Cry2 double KO mice
Series Id: GSE13062
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
8254057 | J:81265
First Author: Linton MF
Year: 1993
Journal: J Clin Invest
Title: Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).
Volume: 92
Issue: 6
Pages: 3029-37
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Publication
7657833 | J:118801
First Author: Callow MJ
Year: 1995
Journal: J Clin Invest
Title: Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a).
Volume: 96
Issue: 3
Pages: 1639-46
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Protein
F6VIR4
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Publication
7502076 | J:30144
First Author: Chong L
Year: 1995
Journal: Science
Title: A human telomeric protein.
Volume: 270
Issue: 5242
Pages: 1663-7
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Publication
11545737 | -
First Author: Fairall L
Year: 2001
Journal: Mol Cell
Title: Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2.
Volume: 8
Issue: 2
Pages: 351-61
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Publication
9034194 | -
First Author: Cooper JP
Year: 1997
Journal: Nature
Title: Regulation of telomere length and function by a Myb-domain protein in fission yeast.
Volume: 385
Issue: 6618
Pages: 744-7
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Protein Domain
IPR036507 | Telomere_rpt-bd_fac_dimer_sf
Type: Homologous_superfamily
Description: Telomeres function to shield chromosome ends from degradation and end-to-end fusions, as well as preventing the activation of DNA damage checkpoints. Telomeric repeat binding factor (TRF) proteins TRF1 and TRF2 are major components of vertebrate telomeres required for regulation of telomere stability. TRF1 and TRF2 bind to telomeric DNA as homodimers. Dimerisation involves the TRF homology (TRFH) subdomain contained within the dimerisation domain. The TRFH subdomain is important not only for dimerisation, but for DNA binding, telomere localisation, and interactions with other telomeric proteins. The dimerisation domains of TRF1 and TRF2 show the same multi-helical structure, arranged in a solenoid conformation similar to TPR repeats, which can be divided into an α-α superhelix and a long alpha hairpin [].The two related human TRF proteins hTRF1 and hTRF2 form homodimers and bind directly to telomeric TTAGGG repeats via the myb DNA binding domain at the carboxy terminus []. TRF1 is implicated in telomere length regulation and TRF2 in telomere protection []. Other telomere complex associated proteins are recruited through their interaction with either TRF1 or TRF2. The fission yeast protein Taz1p (telomere-associated in Schizosaccharomyces pombe (Fission yeast) has similarity to both hTRF1 and hTRF2 and may perform the dual functions of TRF1 and TRF2 at fission yeast telomeres []. This entry represents the dimerisation domain.
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Protein Domain
IPR017357 | TERF1/2
Type: Family
Description: This group represents telomeric repeat-binding factors 1 (TERF1, also known as TRF1).Telomeres function to shield chromosome ends from degradation and end-to-end fusions, as well as preventing the activation of DNA damage checkpoints. Telomeric repeat binding factor (TRF) proteins TRF1 and TRF2 are major components of vertebrate telomeres required for regulation of telomere stability. TRF1 and TRF2 bind to telomeric DNA as homodimers. Dimerisation involves the TRF homology (TRFH) subdomain contained within the dimerisation domain. The TRFH subdomain is important not only for dimerisation, but for DNA binding, telomere localisation, and interactions with other telomeric proteins. The dimerisation domains of TRF1 and TRF2 show the same multi-helical structure, arranged in a solenoid conformation similar to TPR repeats, which can be divided into an α-α superhelix and a long alpha hairpin [].The two related human TRF proteins hTRF1 and hTRF2 form homodimers and bind directly to telomeric TTAGGG repeats via the myb DNA binding domain at the carboxy terminus []. TRF1 is implicated in telomere length regulation and TRF2 in telomere protection []. Other telomere complex associated proteins are recruited through their interaction with either TRF1 or TRF2. The fission yeast protein Taz1p (telomere-associated in Schizosaccharomyces pombe (Fission yeast) has similarity to both hTRF1 and hTRF2 and may perform the dual functions of TRF1 and TRF2 at fission yeast telomeres [].
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Protein Domain
IPR030657 | TERF2
Type: Family
Description: This entry represents telomeric repeat-binding factor 2 (TERF2, also known as TRF2).Telomeres function to shield chromosome ends from degradation and end-to-end fusions, as well as preventing the activation of DNA damage checkpoints. Telomeric repeat binding factor (TRF) proteins TRF1 and TRF2 are major components of vertebrate telomeres required for regulation of telomere stability. TRF1 and TRF2 bind to telomeric DNA as homodimers. Dimerisation involves the TRF homology (TRFH) subdomain contained within the dimerisation domain. The TRFH subdomain is important not only for dimerisation, but for DNA binding, telomere localisation, and interactions with other telomeric proteins. The dimerisation domains of TRF1 and TRF2 show the same multi-helical structure, arranged in a solenoid conformation similar to TPR repeats, which can be divided into an α-α superhelix and a long alpha hairpin [].The two related human TRF proteins hTRF1 and hTRF2 form homodimers and bind directly to telomeric TTAGGG repeats via the myb DNA binding domain at the carboxy terminus []. TRF1 is implicated in telomere length regulation and TRF2 in telomere protection []. Other telomere complex associated proteins are recruited through their interaction with either TRF1 or TRF2. The fission yeast protein Taz1p (telomere-associated in Schizosaccharomyces pombe (Fission yeast) has similarity to both hTRF1 and hTRF2 and may perform the dual functions of TRF1 and TRF2 at fission yeast telomeres [].
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Protein Domain
IPR013867 | Telomere_rpt-bd_fac_dimer_dom
Type: Domain
Description: Telomeres function to shield chromosome ends from degradation and end-to-end fusions, as well as preventing the activation of DNA damage checkpoints. Telomeric repeat binding factor (TRF) proteins TRF1 and TRF2 are major components of vertebrate telomeres required for regulation of telomere stability. TRF1 and TRF2 bind to telomeric DNA as homodimers. Dimerisation involves the TRF homology (TRFH) subdomain contained within the dimerisation domain. The TRFH subdomain is important not only for dimerisation, but for DNA binding, telomere localisation, and interactions with other telomeric proteins. The dimerisation domains of TRF1 and TRF2 show the same multi-helical structure, arranged in a solenoid conformation similar to TPR repeats, which can be divided into an α-α superhelix and a long alpha hairpin [].The two related human TRF proteins hTRF1 and hTRF2 form homodimers and bind directly to telomeric TTAGGG repeats via the myb DNA binding domain at the carboxy terminus []. TRF1 is implicated in telomere length regulation and TRF2 in telomere protection []. Other telomere complex associated proteins are recruited through their interaction with either TRF1 or TRF2. The fission yeast protein Taz1p (telomere-associated in Schizosaccharomyces pombe (Fission yeast) has similarity to both hTRF1 and hTRF2 and may perform the dual functions of TRF1 and TRF2 at fission yeast telomeres []. This entry represents the dimerisation domain.
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Publication
9539774 | J:47464
First Author: Sanan DA
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a).
Volume: 95
Issue: 8
Pages: 4544-9
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Publication
25593281 | J:249180
First Author: Patel KM
Year: 2015
Journal: Circ Res
Title: Macrophage sortilin promotes LDL uptake, foam cell formation, and atherosclerosis.
Volume: 116
Issue: 5
Pages: 789-96
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Publication
20976059 | J:166224
First Author: Kassim SH
Year: 2010
Journal: PLoS One
Title: Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.
Volume: 5
Issue: 10
Pages: e13424
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HT Experiment
GSE236874 | Impact of different tissue dissociation protocols on endothelial cell recovery from developing lungs.
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
8429912 | -
First Author: Crowley TE
Year: 1993
Journal: Nature
Title: A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila.
Volume: 361
Issue: 6412
Pages: 557-61
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Publication
8183889 | -
First Author: Marsh TL
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor IID in the Archaea: sequences in the Thermococcus celer genome would encode a product closely related to the TATA-binding protein of eukaryotes.
Volume: 91
Issue: 10
Pages: 4180-4
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Publication
12080061 | J:78777
First Author: Sbodio JI
Year: 2002
Journal: J Biol Chem
Title: Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner.
Volume: 277
Issue: 35
Pages: 31887-92
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Protein Domain
IPR030491 | TBP_CS
Type: Conserved_site
Description: Transcription factor TFIID (or TATA-binding protein, TBP) []is a generalfactor that plays a major role in the activation of eukaryotic genestranscribed by RNA polymerase II. TFIID binds specifically to the TATA boxpromoter element which lies close to the position of transcription initiation.There is a remarkable degree of sequence conservation of a C-terminal domainof about 180 residues in TFIID from various eukaryotic sources. This region isnecessary and sufficient for TATA box binding. The most significant structuralfeature of this domain is the presence of two conserved repeats of a 77 amino-acid region. The intramolecular symmetry generates a saddle-shaped structurethat sits astride the DNA [].Drosophila TRF (TBP-related factor) []is a sequence-specific transcriptionfactor that also binds to the TATA box and is highly similar to TFIID. Archaebacteria also possess a TBP homologue [].This entry represents a conserved site that spans the last 50 residues of therepeated region.
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Publication
30174302 | J:272007
First Author: Chaix A
Year: 2019
Journal: Cell Metab
Title: Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock.
Volume: 29
Issue: 2
Pages: 303-319.e4
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Publication
38325337 | J:345953
First Author: Williams AS
Year: 2024
Journal: Cell Metab
Title: Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding.
Volume: 36
Issue: 2
Pages: 422-437.e8
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Publication
37607543 | J:341731
First Author: Whittaker DS
Year: 2023
Journal: Cell Metab
Title: Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer's disease.
Volume: 35
Issue: 10
Pages: 1704-1721.e6
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Publication
30507571 | J:352643
First Author: Wan Nasri WN
Year: 2019
Journal: J Alzheimers Dis
Title: Tocotrienol Rich Fraction Supplementation Modulate Brain Hippocampal Gene Expression in APPswe/PS1dE9 Alzheimer's Disease Mouse Model.
Volume: 70
Issue: s1
Pages: S239-S254
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Publication
35059607 | J:337328
First Author: Hopp K
Year: 2022
Journal: iScience
Title: Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease.
Volume: 25
Issue: 1
Pages: 103697
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Publication
35521538 | J:328751
First Author: Zhai Q
Year: 2022
Journal: iScience
Title: Time-restricted feeding entrains long-term behavioral changes through the IGF2-KCC2 pathway.
Volume: 25
Issue: 5
Pages: 104267
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Publication
1505947 | J:18244
First Author: Maccarone P
Year: 1992
Journal: Genomics
Title: The evolution of human chromosome 21: evidence from in situ hybridization in marsupials and a monotreme.
Volume: 13
Issue: 4
Pages: 1119-24
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Publication
37437544 | J:338215
First Author: Duregon E
Year: 2023
Journal: Cell Metab
Title: Prolonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice.
Volume: 35
Issue: 7
Pages: 1179-1194.e5
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Publication
- | J:46866
     
First Author: Levy JE
Year: 1998
Journal: MGI Direct Data Submission
Title: The Transferrin Receptor (Trfr) maps to mouse Chromosome 16
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Protein
Q8C9B6
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Protein
Q8C806
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Publication
15316005 | -
First Author: Ye JZ
Year: 2004
Journal: J Biol Chem
Title: TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.
Volume: 279
Issue: 45
Pages: 47264-71
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Protein
P70371
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
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Protein
E9QM06
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: false
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Protein
Q7TSK8
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
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Protein
Q3V252
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
O35144
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Protein
D3YZ08
Organism: Mus musculus/domesticus
Length: 540  
Fragment?: false
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Publication
9889269 | J:52876
First Author: Ohbayashi T
Year: 1999
Journal: Nucleic Acids Res
Title: Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor.
Volume: 27
Issue: 3
Pages: 750-5
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Publication
3024009 | J:8504
First Author: Kinashi T
Year: 1986
Journal: Nature
Title: Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II.
Volume: 324
Issue: 6092
Pages: 70-3
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Publication
14634207 | J:87288
First Author: Persengiev SP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.
Volume: 100
Issue: 25
Pages: 14887-91
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Publication
10192390 | J:54107
First Author: Levy JE
Year: 1999
Journal: Nat Genet
Title: Transferrin receptor is necessary for development of erythrocytes and the nervous system.
Volume: 21
Issue: 4
Pages: 396-9
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Publication
34161259 | J:312126
 
First Author: Hou T
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Time-restricted feeding protects the blood pressure circadian rhythm in diabetic mice.
Volume: 118
Issue: 25
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Publication
32864176 | J:350767
First Author: Zhang Z
Year: 2020
Journal: Sci Bull (Beijing)
Title: Impaired function of the suprachiasmatic nucleus rescues the loss of body temperature homeostasis caused by time-restricted feeding.
Volume: 65
Issue: 15
Pages: 1268-1280
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Publication
37022664 | J:341986
First Author: Hua L
Year: 2023
Journal: FASEB J
Title: Liver-derived FGF21 is required for the effect of time-restricted feeding on high-fat diet-induced fatty liver in mice.
Volume: 37
Issue: 5
Pages: e22898
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Publication
33135359 | J:307627
First Author: Hua L
Year: 2020
Journal: Clin Transl Med
Title: Time-restricted feeding improves the reproductive function of female mice via liver fibroblast growth factor 21.
Volume: 10
Issue: 6
Pages: e195
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Publication
38338668 | J:360417
 
First Author: Jung IR
Year: 2024
Journal: Int J Mol Sci
Title: Time-Restricted Feeding Ameliorates Methionine-Choline Deficient Diet-Induced Steatohepatitis in Mice.
Volume: 25
Issue: 3
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Publication
36285301 | J:332347
 
First Author: Shu YY
Year: 2022
Journal: Oxid Med Cell Longev
Title: Attenuation by Time-Restricted Feeding of High-Fat and High-Fructose Diet-Induced NASH in Mice Is Related to Per2 and Ferroptosis.
Volume: 2022
Pages: 8063897
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Publication
7026423 | J:6596
First Author: Takatsu K
Year: 1981
Journal: Immunol Lett
Title: X-linked recessive inheritance of a defective responsiveness to T-cell-replacing factor in DBA/2Ha mice.
Volume: 3
Issue: 3
Pages: 137-43
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Publication
7893483 | J:21822
First Author: Krzanowska H
Year: 1994
Journal: Mol Reprod Dev
Title: Frequency of X-Y chromosome dissociation in mouse spermatocytes from interstrain crosses, recombinant inbred strains, and chimeras: possible involvement of paternal genome imprinting.
Volume: 39
Issue: 4
Pages: 347-54
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Publication
9857231 | J:52711
First Author: Kiyozuka Y
Year: 1998
Journal: Int J Mol Med
Title: Telomere length, telomerase activity and telomerase RNA expression during mouse mammary tumor progression.
Volume: 2
Issue: 4
Pages: 437-44
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Publication
31746776 | J:293393
First Author: Zhang S
Year: 2019
Journal: Aging (Albany NY)
Title: Identification of functional tRNA-derived fragments in senescence-accelerated mouse prone 8 brain.
Volume: 11
Issue: 22
Pages: 10485-10498
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Publication
31560576 | J:297688
First Author: Falconi M
Year: 2019
Journal: FASEB J
Title: A novel 3'-tRNAGlu-derived fragment acts as a tumor suppressor in breast cancer by targeting nucleolin.
Volume: 33
Issue: 12
Pages: 13228-13240
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Publication
33495474 | J:301011
First Author: Das M
Year: 2021
Journal: Nat Commun
Title: Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models.
Volume: 12
Issue: 1
Pages: 565
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Publication
2374612 | -
First Author: Hoffman A
Year: 1990
Journal: Nature
Title: Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID).
Volume: 346
Issue: 6282
Pages: 387-90
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Publication
33735897 | J:332470
First Author: Wang W
Year: 2022
Journal: Neuroendocrinology
Title: Time-Restricted Feeding Restored Insulin-Growth Hormone Balance and Improved Substrate and Energy Metabolism in MC4RKO Obese Mice.
Volume: 112
Issue: 2
Pages: 174-185
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Publication
30525042 | J:268837
 
First Author: Sabbir MG
Year: 2018
Journal: Front Mol Biosci
Title: Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease.
Volume: 5
Pages: 99
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Protein
Q9R0X0
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
G3UVU6
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: false
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Protein
A2T4N7
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Protein
Q91YM5
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
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Publication
9933582 | -
First Author: Xiao H
Year: 1999
Journal: J Biol Chem
Title: The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex.
Volume: 274
Issue: 7
Pages: 3937-40
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Protein Domain
IPR013921 | Mediator_Med20
Type: Family
Description: The Mediator complex is a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. On recruitment the Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. The Mediator complex is composed of at least 31 subunits: MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The subunits form at least three structurally distinct submodules. The head and the middle modules interact directly with RNA polymerase II, whereas the elongated tail module interacts with gene-specific regulatory proteins. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation.The head module contains: MED6, MED8, MED11, SRB4/MED17, SRB5/MED18, ROX3/MED19, SRB2/MED20 and SRB6/MED22. The middle module contains: MED1, MED4, NUT1/MED5, MED7, CSE2/MED9, NUT2/MED10, SRB7/MED21 and SOH1/MED31. CSE2/MED9 interacts directlywith MED4. The tail module contains: MED2, PGD1/MED3, RGR1/MED14, GAL11/MED15 and SIN4/MED16. The CDK8 module contains: MED12, MED13, CCNC and CDK8. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.Proteins in this entry are subunit Med20 of the Mediator complex, and is found in the non-essential part of the head []. and related to the TATA-binding protein (TBP). TBP is a highly conserved RNA polymerase II general transcription factor that binds to the core promoter and initiates assembly of the pre-initiation complex. Human TRF has been shown to associate with an RNA polymerase II-SRB complex [].
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Protein
Q6SJ95
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
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Protein
P29037
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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Protein
Z4YMT0
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: true
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Protein
B7ZMZ6
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: false
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Protein
Q6RI65
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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Protein
F8WJ67
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: true
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Publication
1436073 | -
First Author: Nikolov DB
Year: 1992
Journal: Nature
Title: Crystal structure of TFIID TATA-box binding protein.
Volume: 360
Issue: 6399
Pages: 40-6
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Publication
- | J:13688
 
First Author: Hilgers J
Year: 1976
Journal: Mouse News Lett
Title: Inbred strains and markers.
Volume: 54
Pages: 30-1
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Publication
15175151 | J:90894
First Author: Bourbon HM
Year: 2004
Journal: Mol Cell
Title: A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Volume: 14
Issue: 5
Pages: 553-7
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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