| Type |
Details |
Score |
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| First Author: |
Michaud JL |
| Year: |
1998 |
| Journal: |
Genes Dev |
| Title: |
Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1. |
| Volume: |
12 |
| Issue: |
20 |
| Pages: |
3264-75 |
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•
•
•
•
•
|
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| First Author: |
Backman M |
| Year: |
2003 |
| Journal: |
Dev Dyn |
| Title: |
Targeted disruption of mouse Dach1 results in postnatal lethality. |
| Volume: |
226 |
| Issue: |
1 |
| Pages: |
139-44 |
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•
•
•
•
•
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| First Author: |
Goggolidou P |
| Year: |
2013 |
| Journal: |
Mamm Genome |
| Title: |
A chronological expression profile of gene activity during embryonic mouse brain development. |
| Volume: |
24 |
| Issue: |
11-12 |
| Pages: |
459-72 |
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•
•
•
•
•
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| First Author: |
Acampora D |
| Year: |
1999 |
| Journal: |
Genes Dev |
| Title: |
Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. |
| Volume: |
13 |
| Issue: |
21 |
| Pages: |
2787-800 |
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•
•
•
•
•
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| Publication |
| First Author: |
Wang W |
| Year: |
2000 |
| Journal: |
Dev Biol |
| Title: |
The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. |
| Volume: |
227 |
| Issue: |
2 |
| Pages: |
432-49 |
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•
•
•
•
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| Publication |
| First Author: |
Schonemann MD |
| Year: |
1995 |
| Journal: |
Genes Dev |
| Title: |
Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. |
| Volume: |
9 |
| Issue: |
24 |
| Pages: |
3122-35 |
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•
•
•
•
•
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| Publication |
| First Author: |
Caqueret A |
| Year: |
2006 |
| Journal: |
Dev Biol |
| Title: |
Laminar organization of the early developing anterior hypothalamus. |
| Volume: |
298 |
| Issue: |
1 |
| Pages: |
95-106 |
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•
•
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| Publication |
| First Author: |
Cheung LYM |
| Year: |
2017 |
| Journal: |
Mol Cell Endocrinol |
| Title: |
Sox21 deletion in mice causes postnatal growth deficiency without physiological disruption of hypothalamic-pituitary endocrine axes. |
| Volume: |
439 |
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| Pages: |
213-223 |
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•
•
•
•
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| Publication |
| First Author: |
van der Zwaag B |
| Year: |
2005 |
| Journal: |
Genomics |
| Title: |
Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. |
| Volume: |
86 |
| Issue: |
1 |
| Pages: |
55-67 |
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•
•
•
•
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| First Author: |
Zupančič M |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
8631 |
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•
•
•
•
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| Publication |
| First Author: |
García-Moreno F |
| Year: |
2010 |
| Journal: |
Nat Neurosci |
| Title: |
A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
680-9 |
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•
•
•
•
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| Publication |
| First Author: |
Newman EA |
| Year: |
2018 |
| Journal: |
Dev Biol |
| Title: |
Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. |
| Volume: |
439 |
| Issue: |
2 |
| Pages: |
102-111 |
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•
•
•
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| Publication |
| First Author: |
Tomás-Roca L |
| Year: |
2016 |
| Journal: |
Brain Struct Funct |
| Title: |
Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. |
| Volume: |
221 |
| Issue: |
2 |
| Pages: |
815-38 |
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•
•
•
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| First Author: |
Hou J |
| Year: |
2007 |
| Journal: |
BMC Dev Biol |
| Title: |
A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE). |
| Volume: |
7 |
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| Pages: |
92 |
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•
•
•
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| First Author: |
Rose MF |
| Year: |
2009 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1. |
| Volume: |
106 |
| Issue: |
52 |
| Pages: |
22462-7 |
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•
•
•
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| First Author: |
Gaston-Massuet C |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Transcription factor 7-like 1 is involved in hypothalamo-pituitary axis development in mice and humans. |
| Volume: |
113 |
| Issue: |
5 |
| Pages: |
E548-57 |
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| First Author: |
Huisman C |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus. |
| Volume: |
12 |
| Issue: |
1 |
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256 |
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| First Author: |
Petitpré C |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
3878 |
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•
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| First Author: |
Feng S |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Abnormal Paraventricular Nucleus of Hypothalamus and Growth Retardation Associated with Loss of Nuclear Receptor Gene COUP-TFII. |
| Volume: |
7 |
| Issue: |
1 |
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5282 |
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| First Author: |
Lu C |
| Year: |
2023 |
| Journal: |
iScience |
| Title: |
Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression. |
| Volume: |
26 |
| Issue: |
5 |
| Pages: |
106670 |
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•
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| First Author: |
Lee B |
| Year: |
2016 |
| Journal: |
Development |
| Title: |
The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. |
| Volume: |
143 |
| Issue: |
20 |
| Pages: |
3763-3773 |
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•
•
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| First Author: |
Jukkola T |
| Year: |
2006 |
| Journal: |
Dev Biol |
| Title: |
FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. |
| Volume: |
297 |
| Issue: |
1 |
| Pages: |
141-57 |
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| First Author: |
Yin Y |
| Year: |
2021 |
| Journal: |
JCI Insight |
| Title: |
Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization. |
| Volume: |
6 |
| Issue: |
17 |
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| First Author: |
Puelles L |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer. |
| Volume: |
24 |
| Issue: |
11 |
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| First Author: |
The Jackson Laboratory |
| Year: |
2005 |
| Journal: |
Unpublished |
| Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
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| First Author: |
Centre for Modeling Human Disease |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto |
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| First Author: |
Toronto Centre for Phenogenomics |
| Year: |
2013 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). |
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| First Author: |
Tamplin OJ |
| Year: |
2008 |
| Journal: |
BMC Genomics |
| Title: |
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. |
| Volume: |
9 |
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| Pages: |
511 |
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•
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| First Author: |
MGI and IMPC |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
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Thompson CL |
| Year: |
2014 |
| Journal: |
Neuron |
| Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
| Volume: |
83 |
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2 |
| Pages: |
309-323 |
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Lennon G |
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Database Download |
| Title: |
WashU-HHMI Mouse EST Project |
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| First Author: |
Velocigene |
| Year: |
2008 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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GUDMAP Consortium |
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2004 |
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www.gudmap.org |
| Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
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Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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| First Author: |
Hansen GM |
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2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
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1670-9 |
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The Gene Ontology Consortium |
| Year: |
2014 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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UniProt-GOA |
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2012 |
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Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
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Gene Ontology annotation through association of InterPro records with GO terms |
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Magdaleno S |
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2006 |
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PLoS Biol |
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
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2024 |
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Nature |
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| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
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Database Download |
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Mouse Gene Trap Data Load from dbGSS |
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Cyagen Biosciences Inc. |
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Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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The Jackson Laboratory Mouse Radiation Hybrid Database |
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Mouse T31 Radiation Hybrid Data Load |
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Nature |
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PLoS Biol |
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MGI Genome Annotation Group and UniGene Staff |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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•
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| Allele |
| Name: |
thyrotropin releasing hormone; endonuclease-mediated mutation 1,Bradford B Lowell |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
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| Allele |
| Name: |
transgene insertion FZ169, GENSAT Project at Rockefeller University |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
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•
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| Strain |
| Attribute String: |
endonuclease-mediated mutation, mutant stock |
|
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| Genotype |
| Symbol: |
Trh/Trh<+> |
| Background: |
involves: FVB |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
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•
•
•
•
|
| Genotype |
| Symbol: |
Trh/Trh |
| Background: |
involves: C57BL/6 * CBA |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
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•
•
•
•
|
| Genotype |
| Symbol: |
Trh/Trh |
| Background: |
involves: C57BL/6 * CBA * ICR |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
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| Publication |
| First Author: |
Ghamari-Langroudi M |
| Year: |
2010 |
| Journal: |
Mol Endocrinol |
| Title: |
Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity. |
| Volume: |
24 |
| Issue: |
12 |
| Pages: |
2366-81 |
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| Allele |
| Name: |
transgene insertion 40, Anthony Hollenberg |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
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| Allele |
| Name: |
transgene insertion 5, Anthony Hollenberg |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
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| Allele |
| Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 67, Elizabeth M Simpson |
| Allele Type: |
Targeted |
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| Strain |
| Attribute String: |
mutant stock, transgenic |
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| Genotype |
| Symbol: |
Tg(Trh-cre)40Anh/? |
| Background: |
involves: C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sugrue ML |
| Year: |
2010 |
| Journal: |
Endocrinology |
| Title: |
The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo. |
| Volume: |
151 |
| Issue: |
2 |
| Pages: |
793-801 |
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•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
257
 |
| Fragment?: |
false |
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•
•
•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
288
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
275
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
276
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
245
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
247
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
310
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
257
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
288
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
159
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
245
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
91
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
124
 |
| Fragment?: |
true |
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•
•
•
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