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Search results 301 to 400 out of 8113 for Trp53

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Type Details Score
Publication
27452466 | J:238866
First Author: Borromeo MD
Year: 2016
Journal: Cell Rep
Title: ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs.
Volume: 16
Issue: 5
Pages: 1259-1272
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Publication
21397855 | J:169931
First Author: Chow LM
Year: 2011
Journal: Cancer Cell
Title: Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain.
Volume: 19
Issue: 3
Pages: 305-16
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Publication
24794706 | J:210599
First Author: Xu C
Year: 2014
Journal: Cancer Cell
Title: Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
Volume: 25
Issue: 5
Pages: 590-604
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Publication
24019382 | J:204513
First Author: Trejo CL
Year: 2013
Journal: Cancer Res
Title: Mutationally activated PIK3CA(H1047R) cooperates with BRAF(V600E) to promote lung cancer progression.
Volume: 73
Issue: 21
Pages: 6448-61
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Publication
33346791 | J:304132
First Author: Chen KS
Year: 2021
Journal: Carcinogenesis
Title: NFIA and NFIB function as tumour suppressors in high-grade glioma in mice.
Volume: 42
Issue: 3
Pages: 357-368
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Publication
29904909 | J:288801
First Author: Sementino E
Year: 2018
Journal: J Cell Physiol
Title: Inactivation of Tp53 and Pten drives rapid development of pleural and peritoneal malignant mesotheliomas.
Volume: 233
Issue: 11
Pages: 8952-8961
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Publication
20046869 | J:155940
First Author: Clark-Knowles KV
Year: 2009
Journal: PLoS One
Title: Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas.
Volume: 4
Issue: 12
Pages: e8534
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Publication
28490518 | J:243118
First Author: Sen T
Year: 2017
Journal: Cancer Res
Title: CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib.
Volume: 77
Issue: 14
Pages: 3870-3884
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Publication
38775153 | J:349095
 
First Author: Meder L
Year: 2024
Journal: JCI Insight
Title: Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis.
Volume: 9
Issue: 10
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Publication
20406986 | J:160148
First Author: Schaffer BE
Year: 2010
Journal: Cancer Res
Title: Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma.
Volume: 70
Issue: 10
Pages: 3877-83
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Publication
25296641 | J:217182
 
First Author: Chinnam M
Year: 2014
Journal: J Natl Cancer Inst
Title: The Thoc1 ribonucleoprotein and prostate cancer progression.
Volume: 106
Issue: 11
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Publication
25263199 | J:217191
First Author: Zhang Y
Year: 2014
Journal: Dev Biol
Title: Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.
Volume: 396
Issue: 1
Pages: 19-30
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Publication
22190384 | J:211100
First Author: Antico Arciuch VG
Year: 2011
Journal: Oncotarget
Title: Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors.
Volume: 2
Issue: 12
Pages: 1109-26
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Publication
31270502 | J:306050
First Author: Segovia C
Year: 2019
Journal: Nat Med
Title: Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression.
Volume: 25
Issue: 7
Pages: 1073-1081
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36413415 | J:333108
 
First Author: Seidel P
Year: 2022
Journal: JCI Insight
Title: ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.
Volume: 7
Issue: 24
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Publication
30181244 | J:266828
First Author: Jia D
Year: 2018
Journal: Cancer Discov
Title: Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition.
Volume: 8
Issue: 11
Pages: 1422-1437
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Publication
20442289 | J:160565
First Author: Rubio R
Year: 2010
Journal: Cancer Res
Title: Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo.
Volume: 70
Issue: 10
Pages: 4185-94
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Publication
32265224 | J:288999
First Author: Zhao H
Year: 2020
Journal: Cancer Res
Title: Targeted Inhibition of the E3 Ligase SCFSkp2/Cks1 Has Antitumor Activity in RB1-Deficient Human and Mouse Small-Cell Lung Cancer.
Volume: 80
Issue: 11
Pages: 2355-2367
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22574128 | J:187257
First Author: Westerman BA
Year: 2012
Journal: PLoS One
Title: GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.
Volume: 7
Issue: 5
Pages: e35943
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36690626 | J:332811
First Author: Gao G
Year: 2023
Journal: Nat Commun
Title: The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer.
Volume: 14
Issue: 1
Pages: 363
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Publication
29776963 | J:264257
First Author: Meder L
Year: 2018
Journal: Cancer Res
Title: Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer.
Volume: 78
Issue: 15
Pages: 4270-4281
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Publication
24444712 | J:211600
First Author: Cho H
Year: 2014
Journal: Cancer Discov
Title: RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.
Volume: 4
Issue: 3
Pages: 318-33
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25490451 | J:217744
First Author: Christensen CL
Year: 2014
Journal: Cancer Cell
Title: Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor.
Volume: 26
Issue: 6
Pages: 909-922
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Publication
32023457 | J:288080
First Author: Fagan-Solis KD
Year: 2020
Journal: Cell Rep
Title: A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability.
Volume: 30
Issue: 5
Pages: 1385-1399.e7
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Publication
31806642 | J:285700
First Author: McCool KW
Year: 2020
Journal: Cancer Res
Title: Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts.
Volume: 80
Issue: 4
Pages: 877-889
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34294854 | J:308631
First Author: Murakami T
Year: 2021
Journal: Sci Rep
Title: Distinctive detection of insulinoma using [18F]FB(ePEG12)12-exendin-4 PET/CT.
Volume: 11
Issue: 1
Pages: 15014
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Publication
19951992 | J:155394
First Author: He F
Year: 2009
Journal: Cancer Res
Title: Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.
Volume: 69
Issue: 24
Pages: 9413-21
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Publication
25056937 | J:317519
First Author: Nazarian A
Year: 2014
Journal: Mol Cell Proteomics
Title: Inhibition of circulating dipeptidyl peptidase 4 activity in patients with metastatic prostate cancer.
Volume: 13
Issue: 11
Pages: 3082-96
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Publication
27869166 | J:241247
First Author: Lu W
Year: 2017
Journal: Oncogene
Title: SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.
Volume: 36
Issue: 10
Pages: 1364-1373
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Publication
37055829 | J:334748
First Author: Alvarez-Arzola R
Year: 2023
Journal: Cell Commun Signal
Title: VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer.
Volume: 21
Issue: 1
Pages: 76
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24866151 | J:217845
First Author: González-Billalabeitia E
Year: 2014
Journal: Cancer Discov
Title: Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.
Volume: 4
Issue: 8
Pages: 896-904
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Publication
23845440 | J:199223
First Author: Karantanos T
Year: 2013
Journal: Cancer Cell
Title: GEMMs shine a light on resistance to androgen deprivation therapy for prostate cancer.
Volume: 24
Issue: 1
Pages: 11-3
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Publication
28274958 | J:243131
First Author: Patnaik A
Year: 2017
Journal: Cancer Discov
Title: Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.
Volume: 7
Issue: 7
Pages: 750-765
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Publication
33186519 | J:300350
First Author: Guccini I
Year: 2021
Journal: Cancer Cell
Title: Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis.
Volume: 39
Issue: 1
Pages: 68-82.e9
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Publication
29309058 | J:275855
First Author: Bezzi M
Year: 2018
Journal: Nat Med
Title: Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms.
Volume: 24
Issue: 2
Pages: 165-175
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Publication
25099011 | J:216207
First Author: Xie Y
Year: 2014
Journal: Mol Endocrinol
Title: Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer.
Volume: 28
Issue: 10
Pages: 1629-39
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Publication
15898111 | J:99580
First Author: Kalitsis P
Year: 2005
Journal: Genes Chromosomes Cancer
Title: Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice.
Volume: 44
Issue: 1
Pages: 29-36
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9425920 | J:90869
First Author: Yin L
Year: 1998
Journal: Hepatology
Title: Control of mouse hepatocyte proliferation and ploidy by p53 and p53ser246 mutation in vivo.
Volume: 27
Issue: 1
Pages: 73-80
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Publication
22307631 | J:182031
First Author: Goh AM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity.
Volume: 109
Issue: 5
Pages: 1685-90
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17713479 | J:126758
First Author: Yan CT
Year: 2007
Journal: Nature
Title: IgH class switching and translocations use a robust non-classical end-joining pathway.
Volume: 449
Issue: 7161
Pages: 478-82
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30072430 | J:264598
First Author: Crowe JL
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination.
Volume: 115
Issue: 34
Pages: 8615-8620
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34521752 | J:310613
 
First Author: Wang XS
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice.
Volume: 118
Issue: 38
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20010689 | J:155801
First Author: Gostissa M
Year: 2009
Journal: Nature
Title: Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.
Volume: 462
Issue: 7274
Pages: 803-7
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Publication
28759779 | J:277029
 
First Author: Xing M
Year: 2017
Journal: DNA Repair (Amst)
Title: Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.
Volume: 57
Pages: 133-138
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Publication
29903771 | J:266012
First Author: Wasylishen AR
Year: 2018
Journal: Mol Cancer Res
Title: Daxx Functions Are p53-Independent In Vivo.
Volume: 16
Issue: 10
Pages: 1523-1529
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Publication
12829028 | J:115677
First Author: TeKippe M
Year: 2003
Journal: Exp Hematol
Title: Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice.
Volume: 31
Issue: 6
Pages: 521-7
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25818648 | J:220823
First Author: Jiang W
Year: 2015
Journal: Mol Cell
Title: Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.
Volume: 58
Issue: 1
Pages: 172-85
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Publication
10319859 | J:54533
First Author: Xu X
Year: 1999
Journal: Nat Genet
Title: Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
Volume: 22
Issue: 1
Pages: 37-43
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16585167 | J:108217
First Author: Smolen GA
Year: 2006
Journal: Cancer Res
Title: Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis.
Volume: 66
Issue: 7
Pages: 3452-5
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Publication
16151013 | J:101198
First Author: Chipuk JE
Year: 2005
Journal: Science
Title: PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.
Volume: 309
Issue: 5741
Pages: 1732-5
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Publication
39395421 | J:358349
First Author: Ross JL
Year: 2024
Journal: Immunity
Title: Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Volume: 57
Issue: 11
Pages: 2669-2687.e6
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20679727 | J:165289
First Author: Jiang Z
Year: 2010
Journal: J Clin Invest
Title: Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.
Volume: 120
Issue: 9
Pages: 3296-309
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Publication
23708211 | J:199111
First Author: Guijarro MV
Year: 2013
Journal: Am J Pathol
Title: Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling.
Volume: 182
Issue: 6
Pages: 2015-27
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24823640 | J:210591
First Author: Aytes A
Year: 2014
Journal: Cancer Cell
Title: Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.
Volume: 25
Issue: 5
Pages: 638-651
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28119454 | J:264655
First Author: Song H
Year: 2017
Journal: J Biol Chem
Title: Selective Ablation of Tumor Suppressors in Parafollicular C Cells Elicits Medullary Thyroid Carcinoma.
Volume: 292
Issue: 9
Pages: 3888-3899
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Publication
26359368 | J:231492
First Author: Garcia-Rendueles ME
Year: 2015
Journal: Cancer Discov
Title: NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
Volume: 5
Issue: 11
Pages: 1178-93
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Publication
35700263 | J:326989
First Author: Qin Q
Year: 2022
Journal: Cancer Res
Title: NELL1 Regulates the Matrisome to Promote Osteosarcoma Progression.
Volume: 82
Issue: 15
Pages: 2734-2747
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18988856 | J:141066
First Author: Park KK
Year: 2008
Journal: Science
Title: Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway.
Volume: 322
Issue: 5903
Pages: 963-6
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34788609 | J:321169
First Author: Taranda J
Year: 2021
Journal: Cell Rep
Title: Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases.
Volume: 37
Issue: 7
Pages: 110027
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Publication
32807776 | J:303341
First Author: Hoefflin R
Year: 2020
Journal: Nat Commun
Title: HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Volume: 11
Issue: 1
Pages: 4111
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21831840 | J:175978
First Author: Hwang CI
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Wild-type p53 controls cell motility and invasion by dual regulation of MET expression.
Volume: 108
Issue: 34
Pages: 14240-5
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27571409 | J:236979
First Author: Jones RA
Year: 2016
Journal: J Clin Invest
Title: RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.
Volume: 126
Issue: 10
Pages: 3739-3757
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28489825 | J:252519
First Author: Lim JS
Year: 2017
Journal: Nature
Title: Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Volume: 545
Issue: 7654
Pages: 360-364
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35653190 | J:332383
 
First Author: Kumar R
Year: 2022
Journal: J Clin Invest
Title: A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60.
Volume: 132
Issue: 13
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16510568 | J:106703
First Author: Daikoku T
Year: 2006
Journal: Cancer Res
Title: Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.
Volume: 66
Issue: 5
Pages: 2527-31
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39186687 | J:360596
First Author: MacLeod G
Year: 2024
Journal: Cancer Res
Title: Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities.
Volume: 84
Issue: 23
Pages: 3967-3983
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30753823 | J:271233
First Author: Carugo A
Year: 2019
Journal: Cancer Cell
Title: p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Volume: 35
Issue: 2
Pages: 204-220.e9
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30833574 | J:273261
First Author: Hoeman CM
Year: 2019
Journal: Nat Commun
Title: ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
Volume: 10
Issue: 1
Pages: 1023
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29437778 | J:262260
     
First Author: Jurmeister S
Year: 2018
Journal: EMBO Mol Med
Title: Identification of potential therapeutic targets in prostate cancer through a cross-species approach.
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31883968 | J:283653
First Author: Zhang H
Year: 2020
Journal: Cancer Cell
Title: CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Volume: 37
Issue: 1
Pages: 37-54.e9
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22464334 | J:243760
First Author: Farago AF
Year: 2012
Journal: Cell
Title: SnapShot: Lung cancer models.
Volume: 149
Issue: 1
Pages: 246-246.e1
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38016952 | J:360598
First Author: Ji Y
Year: 2023
Journal: Nat Commun
Title: The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer.
Volume: 14
Issue: 1
Pages: 7794
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Publication
34535684 | J:312395
First Author: Langdon CG
Year: 2021
Journal: Nat Commun
Title: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity.
Volume: 12
Issue: 1
Pages: 5520
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30674530 | J:273224
First Author: Beckmann PJ
Year: 2019
Journal: Cancer Res
Title: Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
Volume: 79
Issue: 5
Pages: 905-917
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9537435 | J:47088
First Author: Ghebranious N
Year: 1998
Journal: Hepatology
Title: The mouse equivalent of the human p53ser249 mutation p53ser246 enhances aflatoxin hepatocarcinogenesis in hepatitis B surface antigen transgenic and p53 heterozygous null mice.
Volume: 27
Issue: 4
Pages: 967-73
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7773294 | J:23262
First Author: Harvey M
Year: 1995
Journal: Nat Genet
Title: A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice.
Volume: 9
Issue: 3
Pages: 305-11
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Publication
25526089 | J:260364
First Author: Li L
Year: 2015
Journal: Cell Death Differ
Title: A unique role for p53 in the regulation of M2 macrophage polarization.
Volume: 22
Issue: 7
Pages: 1081-93
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Publication
36106631 | J:336978
 
First Author: Ghosh A
Year: 2022
Journal: J Clin Invest
Title: Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade.
Volume: 132
Issue: 18
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Publication
30355482 | J:266858
First Author: Torgovnick A
Year: 2018
Journal: Cell Rep
Title: The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression.
Volume: 25
Issue: 4
Pages: 1027-1039.e6
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Publication
30232008 | J:271028
First Author: Albers E
Year: 2018
Journal: Cell Rep
Title: Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality.
Volume: 24
Issue: 12
Pages: 3274-3284
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
26261055 | J:236511
 
First Author: Yu R
Year: 2016
Journal: Mol Cell Endocrinol
Title: Animal models of spontaneous pancreatic neuroendocrine tumors.
Volume: 421
Pages: 60-7
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Publication
34270926 | J:309426
First Author: Pearson JD
Year: 2021
Journal: Cancer Cell
Title: Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.
Volume: 39
Issue: 8
Pages: 1115-1134.e12
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26123589 | J:236513
 
First Author: Kirschner LS
Year: 2016
Journal: Mol Cell Endocrinol
Title: Mouse models of thyroid cancer: A 2015 update.
Volume: 421
Pages: 18-27
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Publication
23047698 | J:190366
First Author: Song H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis.
Volume: 109
Issue: 43
Pages: 17531-6
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Publication
38330136 | J:345232
First Author: Gardner EE
Year: 2024
Journal: Science
Title: Lineage-specific intolerance to oncogenic drivers restricts histological transformation.
Volume: 383
Issue: 6683
Pages: eadj1415
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