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Search results 301 to 400 out of 686 for Tsc2

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Hits by Strain

Type Details Score
GXD Expression      
Probe: MGI:7471059
Assay Type: Western blot
Annotation Date: 2023-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7471073
Age: embryonic day 17.0
Specimen Label: Embryo
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7471059
Assay Type: Western blot
Annotation Date: 2023-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7471073
Age: postnatal week 2
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7471059
Assay Type: Western blot
Annotation Date: 2023-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7471073
Age: postnatal week 4
Specimen Label: 4
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7471059
Assay Type: Western blot
Annotation Date: 2023-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7471073
Age: postnatal week 8
Specimen Label: 8
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7471059
Assay Type: Western blot
Annotation Date: 2023-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7471073
Age: postnatal week 20
Specimen Label: 20
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7471059
Assay Type: Western blot
Annotation Date: 2023-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7471073
Age: postnatal week 50
Specimen Label: 50
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529192
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529192
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529192
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529192
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529192
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529192
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529192
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7529181
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529192
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529193
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529193
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529193
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529193
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529193
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529193
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529193
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7529182
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529193
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945083
Age: embryonic day 11.5
Image: g00535 E11.5
Specimen Label: g00535 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945083
Age: embryonic day 11.5
Image: g00535 E11.5
Specimen Label: g00535 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945083
Age: embryonic day 11.5
Image: g00535 E11.5
Specimen Label: g00535 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Note: Expression was region specific and scattered.
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945083
Age: embryonic day 11.5
Image: g00535 E11.5
Specimen Label: g00535 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945083
Age: embryonic day 11.5
Image: g00535 E11.5
Specimen Label: g00535 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Note: Expression was region specific and scattered.
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945083
Age: embryonic day 15.5
Image: g00535 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00535 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884251
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945083
Age: postnatal day 7
Image: g00535 P7
Specimen Label: g00535 P7
Detected: true
Specimen Num: 3
Publication
First Author: Chen H
Year: 2025
Journal: Cell
Title: Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration.
Volume: 188
Issue: 1
Pages: 157-174.e22
Publication
First Author: Sarker AH
Year: 1998
Journal: J Mol Biol
Title: Cloning and characterization of a mouse homologue (mNthl1) of Escherichia coli endonuclease III.
Volume: 282
Issue: 4
Pages: 761-74
Publication    
First Author: Lim S
Year: 2021
Journal: Elife
Title: mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia.
Volume: 10
Publication
First Author: Benthall KN
Year: 2021
Journal: Cell Rep
Title: Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning.
Volume: 36
Issue: 6
Pages: 109511
Publication
First Author: Barone S
Year: 2023
Journal: Am J Pathol
Title: Identification of an Electrogenic 2Cl(-)/H(+) Exchanger, ClC5, as a Chloride-Secreting Transporter Candidate in Kidney Cyst Epithelium in Tuberous Sclerosis.
Volume: 193
Issue: 2
Pages: 191-200
Publication
First Author: Conn CS
Year: 2013
Journal: Sci Signal
Title: Nutrient signaling in protein homeostasis: an increase in quantity at the expense of quality.
Volume: 6
Issue: 271
Pages: ra24
Publication
First Author: Sugiura H
Year: 2022
Journal: J Neurosci
Title: A Farnesyltransferase Inhibitor Restores Cognitive Deficits in Tsc2(+/-) Mice through Inhibition of Rheb1.
Volume: 42
Issue: 12
Pages: 2598-2612
Publication
First Author: Wu J
Year: 2014
Journal: J Immunol
Title: Tuberous sclerosis 1 promotes invariant NKT cell anergy and inhibits invariant NKT cell-mediated antitumor immunity.
Volume: 192
Issue: 6
Pages: 2643-50
Publication
First Author: Taneike M
Year: 2016
Journal: PLoS One
Title: mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.
Volume: 11
Issue: 3
Pages: e0152628
Publication
First Author: Alejandro EU
Year: 2014
Journal: J Clin Invest
Title: Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring.
Volume: 124
Issue: 10
Pages: 4395-410
Publication
First Author: Zhang L
Year: 2012
Journal: PLoS One
Title: TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice.
Volume: 7
Issue: 2
Pages: e30592
Publication  
First Author: Davogustto GE
Year: 2021
Journal: J Mol Cell Cardiol
Title: Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy.
Volume: 158
Pages: 115-127
Publication  
First Author: Akhaphong B
Year: 2021
Journal: JCI Insight
Title: Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice.
Volume: 6
Issue: 13
Publication
First Author: Moore CE
Year: 2015
Journal: Mol Cell Biol
Title: Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia.
Volume: 35
Issue: 10
Pages: 1788-804
Publication
First Author: Peña-Llopis S
Year: 2011
Journal: EMBO J
Title: Regulation of TFEB and V-ATPases by mTORC1.
Volume: 30
Issue: 16
Pages: 3242-58
Publication
First Author: Young RM
Year: 2013
Journal: Genes Dev
Title: Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress.
Volume: 27
Issue: 10
Pages: 1115-31
Publication
First Author: Himes BE
Year: 2018
Journal: PLoS One
Title: Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells.
Volume: 13
Issue: 5
Pages: e0197105
Publication
First Author: Stepanova V
Year: 2017
Journal: J Biol Chem
Title: Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
Volume: 292
Issue: 50
Pages: 20528-20543
Publication
First Author: Krishnamoorthy J
Year: 2018
Journal: Cell Death Dis
Title: Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
Volume: 9
Issue: 3
Pages: 254
Publication  
First Author: Switon K
Year: 2017
Journal: Neuroscience
Title: Molecular neurobiology of mTOR.
Volume: 341
Pages: 112-153
Publication
First Author: Pasteris NG
Year: 1999
Journal: Genomics
Title: Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues.
Volume: 60
Issue: 1
Pages: 57-66
Publication
First Author: Auerbach BD
Year: 2011
Journal: Nature
Title: Mutations causing syndromic autism define an axis of synaptic pathophysiology.
Volume: 480
Issue: 7375
Pages: 63-8
Publication  
First Author: Bey AL
Year: 2014
Journal: Curr Protoc Pharmacol
Title: Overview of mouse models of autism spectrum disorders.
Volume: 66
Pages: 5.66.1-26
Publication
First Author: Yang J
Year: 2015
Journal: Oncogene
Title: Renal tumours in a Tsc2(+/-) mouse model do not show feedback inhibition of Akt and are effectively prevented by rapamycin.
Volume: 34
Issue: 7
Pages: 922-31
Publication
First Author: Blando J
Year: 2009
Journal: Am J Pathol
Title: PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
Volume: 174
Issue: 5
Pages: 1869-79
Publication
First Author: Wilson JL
Year: 2020
Journal: Cell Rep
Title: Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation.
Volume: 30
Issue: 5
Pages: 1542-1552.e7
Publication
First Author: Sukhbaatar N
Year: 2023
Journal: Blood
Title: Duodenal macrophages control dietary iron absorption via local degradation of transferrin.
Volume: 141
Issue: 23
Pages: 2878-2890
Publication
First Author: Kim K
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Polycystin 1 is required for the structural integrity of blood vessels.
Volume: 97
Issue: 4
Pages: 1731-6
Publication
First Author: Pollizzi KN
Year: 2015
Journal: J Clin Invest
Title: mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
Volume: 125
Issue: 5
Pages: 2090-108
Publication
First Author: Bernard C
Year: 2022
Journal: Science
Title: Cortical wiring by synapse type-specific control of local protein synthesis.
Volume: 378
Issue: 6622
Pages: eabm7466
Publication  
First Author: Pita-Thomas W
Year: 2019
Journal: Exp Neurol
Title: HDAC5 promotes optic nerve regeneration by activating the mTOR pathway.
Volume: 317
Pages: 271-283
Publication
First Author: Schrötter S
Year: 2022
Journal: Cell Rep
Title: The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth.
Volume: 39
Issue: 7
Pages: 110824
Publication
First Author: Burmeister M
Year: 1997
Journal: Mamm Genome
Title: The trefoil gene maps to mouse chromosome 17.
Volume: 8
Issue: 3
Pages: 223-4
Publication
First Author: Yasui S
Year: 2007
Journal: Mol Cell Neurosci
Title: The TSC1 gene product hamartin interacts with NADE.
Volume: 35
Issue: 1
Pages: 100-8
Publication
First Author: Finlay GA
Year: 2007
Journal: Cancer Res
Title: Selective inhibition of growth of tuberous sclerosis complex 2 null cells by atorvastatin is associated with impaired Rheb and Rho GTPase function and reduced mTOR/S6 kinase activity.
Volume: 67
Issue: 20
Pages: 9878-86
Publication
First Author: Wang W
Year: 2009
Journal: J Biol Chem
Title: The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis.
Volume: 284
Issue: 6
Pages: 3521-8
Publication
First Author: Barnes EA
Year: 2010
Journal: Am J Respir Cell Mol Biol
Title: The loss of tuberin promotes cell invasion through the ß-catenin pathway.
Volume: 43
Issue: 5
Pages: 617-27
Publication
First Author: La P
Year: 2013
Journal: J Biol Chem
Title: Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: implications for iron metabolism.
Volume: 288
Issue: 18
Pages: 12901-9
Publication
First Author: Kim YM
Year: 2015
Journal: Mol Cell
Title: mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation.
Volume: 57
Issue: 2
Pages: 207-18
Publication
First Author: Aguado C
Year: 2010
Journal: Hum Mol Genet
Title: Laforin, the most common protein mutated in Lafora disease, regulates autophagy.
Volume: 19
Issue: 14
Pages: 2867-76
Publication
First Author: Settembre C
Year: 2012
Journal: EMBO J
Title: A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
Volume: 31
Issue: 5
Pages: 1095-108
Publication
First Author: Chen Z
Year: 2014
Journal: Oncogene
Title: mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression.
Volume: 33
Issue: 37
Pages: 4548-57
Publication
First Author: Antoine MW
Year: 2019
Journal: Neuron
Title: Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.
Volume: 101
Issue: 4
Pages: 648-661.e4
Publication
First Author: Chen N
Year: 2013
Journal: Autophagy
Title: IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway.
Volume: 9
Issue: 8
Pages: 1214-27
Publication
First Author: Valvezan AJ
Year: 2017
Journal: Cancer Cell
Title: mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability.
Volume: 32
Issue: 5
Pages: 624-638.e5
Publication
First Author: Caccamo A
Year: 2013
Journal: Aging Cell
Title: mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.
Volume: 12
Issue: 3
Pages: 370-80
Publication
First Author: Potter WB
Year: 2013
Journal: PLoS Biol
Title: Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling.
Volume: 11
Issue: 8
Pages: e1001627
Publication
First Author: Fritsch SD
Year: 2023
Journal: Cell Metab
Title: Metabolic support by macrophages sustains colonic epithelial homeostasis.
Volume: 35
Issue: 11
Pages: 1931-1943.e8
Publication  
First Author: Minor BMN
Year: 2023
Journal: Endocrinology
Title: Estradiol Augments Tumor-Induced Neutrophil Production to Promote Tumor Cell Actions in Lymphangioleiomyomatosis Models.
Volume: 164
Issue: 6