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Search results 301 to 400 out of 423 for Ube3a

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Type Details Score
Publication
27979975 | J:239308
First Author: Chen CY
Year: 2017
Journal: EMBO Rep
Title: TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology.
Volume: 18
Issue: 1
Pages: 169-183
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Publication
23139813 | J:195360
First Author: Seibt J
Year: 2012
Journal: PLoS One
Title: Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon.
Volume: 7
Issue: 11
Pages: e48675
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Publication
11668390 | J:72512
First Author: Choi JD
Year: 2001
Journal: Mamm Genome
Title: Microarray expression profiling of tissues from mice with uniparental duplications of chromosomes 7 and 11 to identify imprinted genes.
Volume: 12
Issue: 10
Pages: 758-64
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Publication
24125951 | J:206605
First Author: Faisal M
Year: 2014
Journal: Gene
Title: Sexual differences of imprinted genes' expression levels.
Volume: 533
Issue: 1
Pages: 434-8
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Publication
21233130 | J:169234
First Author: Kim JD
Year: 2011
Journal: Hum Mol Genet
Title: Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.
Volume: 20
Issue: 7
Pages: 1353-62
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Publication
35065713 | J:321365
First Author: Knoedler JR
Year: 2022
Journal: Cell
Title: A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior.
Volume: 185
Issue: 4
Pages: 654-671.e22
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Publication
18329113 | J:136723
First Author: Vaillend C
Year: 2008
Journal: Behav Brain Res
Title: Genes, plasticity and mental retardation.
Volume: 192
Issue: 1
Pages: 88-105
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Publication
10767319 | J:61779
First Author: Tarantino LM
Year: 2000
Journal: Hum Mol Genet
Title: Dissection of behavior and psychiatric disorders using the mouse as a model.
Volume: 9
Issue: 6
Pages: 953-65
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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GXD Expression
GXD Expression
   
Probe: MGI:6379308
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379309
Age: postnatal day 10
Image: 1
Specimen Label: Ube3a (m+/p+)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6379308
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379309
Age: postnatal day 10
Image: 1
Specimen Label: Ube3a (m-/p+)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6379308
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379309
Age: postnatal day 60
Image: 1
Specimen Label: Ube3a (m+/p+)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6379308
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379309
Age: postnatal day 60
Image: 1
Specimen Label: Ube3a (m-/p+)
Detected: true
Specimen Num: 4
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HT Experiment
GSE205128 | Molecular and behavioral consequences of Ube3a gene overdosage in mice
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Allele
Ube3a<tm1Jwf> | MGI:2182454
Name: ubiquitin protein ligase E3A; targeted mutation 1, Joseph Wagstaff
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Publication
- | J:302578
     
First Author: Judson MC
Year: 2021
Journal: MGI Direct Data Submission
Title: Direct data submission for Ube3a transgenes.
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GXD Expression
GXD Expression
   
Probe: MGI:6379311
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379313
Age: postnatal day 5
Image: 3
Specimen Label: P5 Ube3a (m+/p+)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6379311
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379313
Age: postnatal day 5
Image: 3
Specimen Label: P5 Ube3a (m-/p+)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6379311
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379313
Age: postnatal day 10
Image: 3
Specimen Label: P10 Ube3a (m+/p+)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6379311
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6379313
Age: postnatal day 10
Image: 3
Specimen Label: P10 Ube3a (m-/p+)
Detected: true
Specimen Num: 4
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Publication
38996019 | J:352296
First Author: Montani C
Year: 2024
Journal: Sci Adv
Title: Sex-biasing influence of autism-associated Ube3a gene overdosage at connectomic, behavioral, and transcriptomic levels.
Volume: 10
Issue: 28
Pages: eadg1421
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Publication
25867122 | J:222719
First Author: Valluy J
Year: 2015
Journal: Nat Neurosci
Title: A coding-independent function of an alternative Ube3a transcript during neuronal development.
Volume: 18
Issue: 5
Pages: 666-73
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Allele
Ube3a<tm1Alb> | MGI:2181811
Name: ubiquitin protein ligase E3A; targeted mutation 1, Arthur L Beaudet
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(Ube3a)5Mpan | MGI:6754127
Name: transgene insertion 5, Matthew Anderson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
11353404 | J:114054
First Author: Herzing LB
Year: 2001
Journal: Am J Hum Genet
Title: The human aminophospholipid-transporting ATPase gene ATP10C maps adjacent to UBE3A and exhibits similar imprinted expression.
Volume: 68
Issue: 6
Pages: 1501-5
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Publication
21131283 | J:356917
First Author: Numata K
Year: 2011
Journal: Nucleic Acids Res
Title: Highly parallel SNP genotyping reveals high-resolution landscape of mono-allelic Ube3a expression associated with locus-wide antisense transcription.
Volume: 39
Issue: 7
Pages: 2649-57
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HT Experiment
E-GEOD-21667 | Highly Parallel SNP Genotyping Reveals High-resolution Landscape of Mono-allelic Ube3a Expression Associated with Locus-wide Antisense Transcription
Series Id: GSE21667
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
31182707 | J:286121
First Author: Lauterborn JC
Year: 2019
Journal: Transl Psychiatry
Title: Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities.
Volume: 9
Issue: 1
Pages: 166
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Publication
15757975 | J:98000
First Author: Makedonski K
Year: 2005
Journal: Hum Mol Genet
Title: MeCP2 deficiency in Rett syndrome causes epigenetic aberrations at the PWS/AS imprinting center that affects UBE3A expression.
Volume: 14
Issue: 8
Pages: 1049-58
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Interaction Experiment
Sun J (2015)
Description: UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis.
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Interaction Experiment
Avagliano Trezza R (2019)
Description: Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome.
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Allele
Ube3a<em1Smoc> | MGI:7293063
Name: ubiquitin protein ligase E3A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429753 | C57BL/6JSmoc-Ube3a<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein
A0A140LHS2
Organism: Mus musculus/domesticus
Length: 126  
Fragment?: true
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Protein
A0A140LI50
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
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Protein
A0A0J9YUK0
Organism: Mus musculus/domesticus
Length: 313  
Fragment?: true
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Protein
A0A0J9YTX6
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: true
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Publication
21947926 | -
First Author: Lemak A
Year: 2011
Journal: J Biomol NMR
Title: Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A.
Volume: 51
Issue: 1-2
Pages: 185-90
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Allele
Tg(tetO-Ube3a*1)1Svd | MGI:5606055
Name: transgene insertion 1, Scott Dindot
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(tetO-Ube3a*2)884Svd | MGI:5606057
Name: transgene insertion 884, Scott Dindot
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Allele
Ube3a<em1Yelg> | MGI:6158669
Name: ubiquitin protein ligase E3A; endonuclease-mediated mutation 1, Ype Elgersma
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
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Allele
Ube3a<em2Yelg> | MGI:6158671
Name: ubiquitin protein ligase E3A; endonuclease-mediated mutation 2, Ype Elgersma
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
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Protein Domain
IPR032353 | AZUL
Type: Domain
Description: The AZUL or amino-terminal zinc-binding domain of ubiquitin E3a ligase (Ube3A) is found in eukaryotes, and is an unusual zinc-finger domain. The final cysteine is usually mutated in Angelman syndrome patients. It is likely that AZUL plays a role in Ube3A substrate-recognition [].
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Protein Domain
IPR042556 | AZUL_sf
Type: Homologous_superfamily
Description: The AZUL or amino-terminal zinc-binding domain of ubiquitin E3a ligase (Ube3A) is found in eukaryotes, and is an unusual zinc-finger domain. The final cysteine is usually mutated in Angelman syndrome patients. It is likely that AZUL plays a role in Ube3A substrate-recognition [].The AZUL domain has a helix-loop-helix architecture with a Zn ion coordinated by four Cys residues arranged in Cys-X(4)-Cys-X(4)-Cys-X(28)-Cys motif [].
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Allele
Del(7Ube3a-Snrpn)1Alb | MGI:2384048
Name: Deletion, Chr 7, Beaudet 1; deletion, Chr 7, Arthur L Beaudet 1
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
28024084 | J:254383
First Author: Kim Y
Year: 2017
Journal: Nat Med
Title: Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome.
Volume: 23
Issue: 2
Pages: 213-222
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Allele
Snhg14<tm1Alb> | MGI:5587826
 
Name: small nucleolar RNA host gene 14; targeted mutation 1, Arthur L Beaudet
Allele Type: Targeted
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Strain
MGI:5587959 | B6.129S7-Snhg14<tm1Alb>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5606054 | FVB/N-Tg(tetO-Ube3a*1)1Svd/J
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:5606056 | FVB/N-Tg(tetO-Ube3a*2)884Svd/J
Attribute String: transgenic, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Del(7Ube3a-Snrpn)1Alb/+
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Snhg14/Snhg14<+>
Background: B6.129S7-Snhg14
Zygosity: ht
Has Mutant Allele: true
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Allele
Del(7Gabrb3-Ube3a)1Yhj | MGI:4830970
Name: deletion, Chr 7, Yong-hui Jiang 1
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:4831135 | B6.129S7-Del(7Gabrb3-Ube3a)1Yhj
Attribute String: congenic, chromosome aberration, deletion, mutant strain, targeted mutation
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Allele
Tg(Ube3a)1Mpan | MGI:5576240
Name: transgene insertion 1, Matthew Anderson
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
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Allele
Tg(Ube3a)1Bdph | MGI:6508670
Name: transgene insertion 1, Benjamin Philpot
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Tg(Ube3a)2Bdph | MGI:6508671
Name: transgene insertion 2, Benjamin Philpot
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Genotype
Genotype
Symbol: Del(7Gabrb3-Ube3a)1Yhj/+
Background: B6.129S7-Del(7Gabrb3-Ube3a)1Yhj
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(7Gabrb3-Ube3a)1Yhj/Del(7Gabrb3-Ube3a)1Yhj
Background: B6.129S7-Del(7Gabrb3-Ube3a)1Yhj
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Snhg14/Snhg14<+> Ube3a/Ube3a<+>
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:5780415 | B6N.FVB-Tg(Ube3a)1Mpan/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5576238 | FVB/NJ-Tg(Ube3a)1Mpan/J
Attribute String: mutant strain, transgenic, coisogenic
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Publication
29996091 | J:271327
First Author: Keaveney MK
Year: 2018
Journal: Cell Rep
Title: A MicroRNA-Based Gene-Targeting Tool for Virally Labeling Interneurons in the Rodent Cortex.
Volume: 24
Issue: 2
Pages: 294-303
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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