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Search results 301 to 352 out of 352 for Usp9x

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Type Details Score
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Zheng X
Year: 2014
Journal: Genes Dev
Title: Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.
Volume: 28
Issue: 13
Pages: 1429-44
Interaction Experiment
Description: Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.
Publication
First Author: Chen X
Year: 2019
Journal: J Proteome Res
Title: Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.
Volume: 18
Issue: 6
Pages: 2654-2665
Interaction Experiment
Description: USP9X counteracts differential ubiquitination of NPHP5 by MARCH7 and BBS11 to regulate ciliogenesis.
Interaction Experiment
Description: USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
Interaction Experiment
Description: Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis.
Allele
Name: ubiquitin specific peptidase 9, X chromosome; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Interaction Experiment
Description: Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKC Kinase Activity.
Publication
First Author: Al-Hakim AK
Year: 2008
Journal: Biochem J
Title: Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains.
Volume: 411
Issue: 2
Pages: 249-60
Publication
First Author: Das A
Year: 2017
Journal: PLoS Genet
Title: USP9X counteracts differential ubiquitination of NPHP5 by MARCH7 and BBS11 to regulate ciliogenesis.
Volume: 13
Issue: 5
Pages: e1006791
Publication  
First Author: Sun XH
Year: 2021
Journal: Biochem Pharmacol
Title: USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
Volume: 188
Pages: 114562
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
DO Term
Publication
First Author: Naik E
Year: 2016
Journal: J Immunol
Title: Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity.
Volume: 196
Issue: 8
Pages: 3438-51
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
DO Term
Publication
First Author: Zhang L
Year: 2012
Journal: Cell Cycle
Title: The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability.
Volume: 11
Issue: 23
Pages: 4378-84
Publication
First Author: Zhang L
Year: 2015
Journal: Cell Rep
Title: The deubiquitinating enzyme USP24 is a regulator of the UV damage response.
Volume: 10
Issue: 2
Pages: 140-7
Publication
First Author: Wang YC
Year: 2016
Journal: Oncogene
Title: Variants of ubiquitin-specific peptidase 24 play a crucial role in lung cancer malignancy.
Volume: 35
Issue: 28
Pages: 3669-80
Publication
First Author: Peterson LF
Year: 2015
Journal: Blood
Title: Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies.
Volume: 125
Issue: 23
Pages: 3588-97
Publication  
First Author: Sun Y
Year: 2018
Journal: J Virol
Title: Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.
Volume: 92
Issue: 13
Protein Domain
Type: Family
Description: Ubiquitin-specific peptidase 24 (USP24, MEROPS identifier C19.047) is a de-ubiquitinating enzyme that is associated with late-onset Parkinson's Disease []. The enzyme is known to remove ubiquitin from damage-specific DNA-binding protein 2 (DDB2), increasing its stability. DDB2 is involved in DNA damage recognition in the nucleotide excision repair pathway, and is a component of an E3 ligase that targets XPC, histones and DDB2 itself []. USP24 also de-ubiquitinates p53, and cells are resistant to apoptosis following UV irradiation if USP24 is depleted because p53 is stabilized []. Single-nucleotide polymorphisms of the USP24 gene have been identified in lung cancer malignancy and could be diagnostic markers for the disease []. The USP24 gene is up-regulated when the USP9X gene is down-regulated by shRNA, leading to increased survival of B-cell myeloma cells []. USP24 positively regulates ferritinophagy, a process in which ferritin is degraded in lysosomes and releases free iron [].
Publication
First Author: Malenczyk K
Year: 2017
Journal: EMBO J
Title: A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.
Volume: 36
Issue: 14
Pages: 2107-2125
Publication
First Author: Wu YR
Year: 2010
Journal: Clin Chim Acta
Title: Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson's disease among Taiwanese.
Volume: 411
Issue: 13-14
Pages: 955-8
Publication
First Author: Taniguchi H
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Possible roles of the transcription factor Nrf1 (NFE2L1) in neural homeostasis by regulating the gene expression of deubiquitinating enzymes.
Volume: 484
Issue: 1
Pages: 176-183
Publication
First Author: Meyerovich K
Year: 2017
Journal: Diabetes
Title: MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells.
Volume: 66
Issue: 9
Pages: 2446-2458
Publication  
First Author: La HM
Year: 2018
Journal: Development
Title: GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance.
Volume: 145
Issue: 18
Publication  
First Author: D'Amico G
Year: 2022
Journal: Development
Title: ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning.
Volume: 149
Issue: 13
Publication
First Author: Koo H
Year: 2025
Journal: Nat Commun
Title: Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development.
Volume: 16
Issue: 1
Pages: 628
Protein
Organism: Mus musculus/domesticus
Length: 2617  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2618  
Fragment?: false