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Search results 301 to 400 out of 523 for Vhl

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Type Details Score
Publication
18184809 | J:131088
First Author: Wan C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration.
Volume: 105
Issue: 2
Pages: 686-91
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15489957 | J:93476
First Author: Karhausen J
Year: 2004
Journal: J Clin Invest
Title: Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.
Volume: 114
Issue: 8
Pages: 1098-106
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Publication
35024767 | J:319520
 
First Author: Krzywinska E
Year: 2022
Journal: J Exp Med
Title: The transcription factor HIF-1α mediates plasticity of NKp46+ innate lymphoid cells in the gut.
Volume: 219
Issue: 2
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Publication
16906157 | J:115017
First Author: Ding M
Year: 2006
Journal: Nat Med
Title: Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice.
Volume: 12
Issue: 9
Pages: 1081-7
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Publication
24298056 | J:205272
First Author: Puri S
Year: 2013
Journal: Genes Dev
Title: VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus.
Volume: 27
Issue: 23
Pages: 2563-75
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Publication
17557118 | J:124039
First Author: Peyssonnaux C
Year: 2007
Journal: J Clin Invest
Title: Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).
Volume: 117
Issue: 7
Pages: 1926-32
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Publication
24646994 | J:208889
First Author: Kusumbe AP
Year: 2014
Journal: Nature
Title: Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone.
Volume: 507
Issue: 7492
Pages: 323-328
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Publication
20733101 | J:179490
First Author: Moslehi J
Year: 2010
Journal: Circulation
Title: Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Volume: 122
Issue: 10
Pages: 1004-16
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Publication
22371328 | J:198097
First Author: Parikh VN
Year: 2012
Journal: Circulation
Title: MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach.
Volume: 125
Issue: 12
Pages: 1520-32
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Publication
17992257 | J:130780
First Author: Hickey MM
Year: 2007
Journal: J Clin Invest
Title: von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Volume: 117
Issue: 12
Pages: 3879-89
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Publication
29480820 | J:261174
First Author: Ghosh MC
Year: 2018
Journal: J Clin Invest
Title: Translational repression of HIF2α expression in mice with Chuvash polycythemia reverses polycythemia.
Volume: 128
Issue: 4
Pages: 1317-1325
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Publication
26215701 | J:238613
First Author: Zhang CS
Year: 2015
Journal: Cell Res
Title: RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.
Volume: 25
Issue: 9
Pages: 1025-42
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Publication
19419968 | J:151178
First Author: Tan SH
Year: 2009
Journal: J Biol Chem
Title: Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor.
Volume: 284
Issue: 27
Pages: 18047-58
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Publication
25023702 | J:221254
First Author: Gómez-Maldonado L
Year: 2015
Journal: Oncogene
Title: EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination.
Volume: 34
Issue: 20
Pages: 2609-20
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Publication
29279301 | J:319826
First Author: Fu C
Year: 2018
Journal: Circ Res
Title: Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.
Volume: 122
Issue: 3
Pages: 457-472
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Publication
15082713 | J:91272
First Author: Hardy MP
Year: 2004
Journal: J Biol Chem
Title: The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory.
Volume: 279
Issue: 26
Pages: 27699-708
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Publication
23042097 | J:193648
First Author: Xue X
Year: 2013
Journal: Carcinogenesis
Title: Hypoxia-inducible factor-2α is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer.
Volume: 34
Issue: 1
Pages: 163-9
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Publication
34301760 | J:310829
First Author: Nguyen-Tran HH
Year: 2021
Journal: Cancer Res
Title: Endothelial Reprogramming Stimulated by Oncostatin M Promotes Inflammation and Tumorigenesis in VHL-Deficient Kidney Tissue.
Volume: 81
Issue: 19
Pages: 5060-5073
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Publication
12832481 | J:84384
First Author: Park SK
Year: 2003
Journal: Mol Cell Biol
Title: Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
Volume: 23
Issue: 14
Pages: 4959-71
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Publication
36413415 | J:333108
 
First Author: Seidel P
Year: 2022
Journal: JCI Insight
Title: ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.
Volume: 7
Issue: 24
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Publication
28553932 | J:251276
First Author: Harlander S
Year: 2017
Journal: Nat Med
Title: Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice.
Volume: 23
Issue: 7
Pages: 869-877
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Publication
24497508 | J:206831
First Author: Ahn GO
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.
Volume: 111
Issue: 7
Pages: 2698-703
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Publication
20194441 | J:263290
First Author: Takeda N
Year: 2010
Journal: Genes Dev
Title: Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis.
Volume: 24
Issue: 5
Pages: 491-501
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Publication
29967068 | J:263648
 
First Author: Kim YE
Year: 2018
Journal: Dis Model Mech
Title: HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.
Volume: 11
Issue: 7
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Publication
24076634 | J:208201
First Author: Doedens AL
Year: 2013
Journal: Nat Immunol
Title: Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen.
Volume: 14
Issue: 11
Pages: 1173-82
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Publication
28473526 | J:243121
First Author: Gu YF
Year: 2017
Journal: Cancer Discov
Title: Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade.
Volume: 7
Issue: 8
Pages: 900-917
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Publication
29666476 | J:269311
First Author: Barben M
Year: 2018
Journal: Cell Death Differ
Title: Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress.
Volume: 25
Issue: 12
Pages: 2071-2085
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Publication
29339479 | J:257753
First Author: Devignes CS
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice.
Volume: 115
Issue: 5
Pages: E992-E1001
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Publication
37117599 | J:339502
First Author: March-Diaz R
Year: 2021
Journal: Nat Aging
Title: Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Volume: 1
Issue: 4
Pages: 385-399
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Publication
23977255 | J:206428
First Author: Puri S
Year: 2013
Journal: PLoS One
Title: Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice.
Volume: 8
Issue: 8
Pages: e72213
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Publication
23290136 | J:194930
First Author: Takubo K
Year: 2013
Journal: Cell Stem Cell
Title: Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.
Volume: 12
Issue: 1
Pages: 49-61
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Publication
24326162 | J:315910
First Author: Lin Q
Year: 2013
Journal: J Am Heart Assoc
Title: Activation of hypoxia-inducible factor-2 in adipocytes results in pathological cardiac hypertrophy.
Volume: 2
Issue: 6
Pages: e000548
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Publication
18490920 | J:140075
First Author: Rankin EB
Year: 2008
Journal: Oncogene
Title: Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice.
Volume: 27
Issue: 40
Pages: 5354-8
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Publication
24101470 | J:201979
First Author: Cowburn AS
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: HIF isoforms in the skin differentially regulate systemic arterial pressure.
Volume: 110
Issue: 43
Pages: 17570-5
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Publication
29035368 | J:252613
First Author: Xie C
Year: 2017
Journal: Nat Med
Title: Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis.
Volume: 23
Issue: 11
Pages: 1298-1308
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Publication
25018103 | J:214629
First Author: Yuen TJ
Year: 2014
Journal: Cell
Title: Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis.
Volume: 158
Issue: 2
Pages: 383-396
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Publication
27991597 | J:243450
 
First Author: Jablonska B
Year: 2016
Journal: Nat Commun
Title: Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury.
Volume: 7
Pages: 13866
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19528226 | J:151523
First Author: Rankin EB
Year: 2009
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor 2 regulates hepatic lipid metabolism.
Volume: 29
Issue: 16
Pages: 4527-38
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Publication
35145086 | J:330302
First Author: Huang B
Year: 2022
Journal: Nat Commun
Title: In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells.
Volume: 13
Issue: 1
Pages: 805
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Publication
29617647 | J:262003
First Author: Sim J
Year: 2018
Journal: Cell Metab
Title: The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.
Volume: 27
Issue: 4
Pages: 898-913.e7
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25023703 | J:221253
First Author: Pritchett TL
Year: 2015
Journal: Oncogene
Title: Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney.
Volume: 34
Issue: 20
Pages: 2631-9
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20628150 | J:165868
First Author: Kapitsinou PP
Year: 2010
Journal: Blood
Title: Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.
Volume: 116
Issue: 16
Pages: 3039-48
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23860500 | J:265110
First Author: Xue X
Year: 2013
Journal: Gastroenterology
Title: Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice.
Volume: 145
Issue: 4
Pages: 831-41
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27798602 | J:243079
First Author: Tyrakis PA
Year: 2016
Journal: Nature
Title: S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.
Volume: 540
Issue: 7632
Pages: 236-241
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22207131 | J:182569
First Author: Ikejiri A
Year: 2012
Journal: Int Immunol
Title: Dynamic regulation of Th17 differentiation by oxygen concentrations.
Volume: 24
Issue: 3
Pages: 137-46
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Publication
9651579 | J:48254
First Author: Ohh M
Year: 1998
Journal: Mol Cell
Title: The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.
Volume: 1
Issue: 7
Pages: 959-68
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Publication
17825299 | J:126834
First Author: Lolkema MP
Year: 2007
Journal: FEBS Lett
Title: The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2.
Volume: 581
Issue: 24
Pages: 4571-6
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9697703 | J:48969
First Author: Street VA
Year: 1998
Journal: Nat Genet
Title: Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice.
Volume: 19
Issue: 4
Pages: 390-4
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Publication
27956697 | J:244844
 
First Author: Triner D
Year: 2017
Journal: Mol Cell Biol
Title: Epithelial Hypoxia-Inducible Factor 2α Facilitates the Progression of Colon Tumors through Recruiting Neutrophils.
Volume: 37
Issue: 5
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Publication
30936475 | J:282921
First Author: Romeo SG
Year: 2019
Journal: Nat Cell Biol
Title: Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation.
Volume: 21
Issue: 4
Pages: 430-441
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16527892 | J:135682
First Author: Liu Y
Year: 2006
Journal: Blood
Title: Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo.
Volume: 108
Issue: 1
Pages: 123-33
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Publication
27444197 | J:246461
First Author: Aarup A
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis.
Volume: 36
Issue: 9
Pages: 1782-90
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25417109 | J:217533
First Author: Okabe K
Year: 2014
Journal: Cell
Title: Neurons limit angiogenesis by titrating VEGF in retina.
Volume: 159
Issue: 3
Pages: 584-96
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30995474 | J:280554
First Author: Fachi JL
Year: 2019
Journal: Cell Rep
Title: Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism.
Volume: 27
Issue: 3
Pages: 750-761.e7
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Publication
37756544 | J:359902
First Author: Ting KKY
Year: 2023
Journal: J Immunol
Title: Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway.
Volume: 211
Issue: 10
Pages: 1561-1577
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38750095 | J:355438
First Author: Ting KKY
Year: 2024
Journal: Sci Rep
Title: Cholesterol accumulation impairs HIF-1α-dependent immunometabolic reprogramming of LPS-stimulated macrophages by upregulating the NRF2 pathway.
Volume: 14
Issue: 1
Pages: 11162
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22490864 | J:188688
First Author: Kobayashi H
Year: 2012
Journal: J Immunol
Title: Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury.
Volume: 188
Issue: 10
Pages: 5106-15
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Publication
19490906 | J:149827
First Author: Krishnan J
Year: 2009
Journal: Cell Metab
Title: Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy.
Volume: 9
Issue: 6
Pages: 512-24
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Publication
29078383 | J:257262
First Author: Xue X
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.
Volume: 114
Issue: 45
Pages: E9608-E9617
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28848049 | J:246046
First Author: Ma X
Year: 2017
Journal: J Biol Chem
Title: Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.
Volume: 292
Issue: 41
Pages: 17046-17056
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10654595 | J:58075
First Author: Voss AK
Year: 2000
Journal: Development
Title: Mice lacking HSP90beta fail to develop a placental labyrinth.
Volume: 127
Issue: 1
Pages: 1-11
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32183943 | J:298376
First Author: Kullmann JA
Year: 2020
Journal: Neuron
Title: Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit.
Volume: 106
Issue: 4
Pages: 607-623.e5
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20544853 | J:168049
First Author: Weidemann A
Year: 2010
Journal: Glia
Title: Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina.
Volume: 58
Issue: 10
Pages: 1177-85
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19809162 | J:154613
First Author: Weidemann A
Year: 2009
Journal: J Clin Invest
Title: The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.
Volume: 119
Issue: 11
Pages: 3373-83
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Publication
26978795 | J:269718
   
First Author: Kurihara T
Year: 2016
Journal: Elife
Title: Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.
Volume: 5
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32332719 | J:294863
First Author: Zhang S
Year: 2020
Journal: Nat Commun
Title: Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways.
Volume: 11
Issue: 1
Pages: 2027
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22556263 | J:189318
First Author: Kim JW
Year: 2012
Journal: Cancer Res
Title: Loss of fibroblast HIF-1α accelerates tumorigenesis.
Volume: 72
Issue: 13
Pages: 3187-95
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15456877 | J:93322
First Author: Biju MP
Year: 2004
Journal: Mol Cell Biol
Title: Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes.
Volume: 24
Issue: 20
Pages: 9038-47
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26503986 | J:252576
First Author: Labrousse-Arias D
Year: 2016
Journal: Cardiovasc Res
Title: HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.
Volume: 109
Issue: 1
Pages: 115-30
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17404621 | J:121253
First Author: Rankin EB
Year: 2007
Journal: J Clin Invest
Title: Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo.
Volume: 117
Issue: 4
Pages: 1068-77
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Publication
26927670 | J:234569
First Author: Farsijani NM
Year: 2016
Journal: J Clin Invest
Title: Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin.
Volume: 126
Issue: 4
Pages: 1425-37
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Publication
36125902 | J:332020
 
First Author: Wang X
Year: 2022
Journal: J Clin Invest
Title: A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle.
Volume: 132
Issue: 23
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26853750 | J:233030
First Author: Ramakrishnan SK
Year: 2016
Journal: Cell Metab
Title: HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.
Volume: 23
Issue: 3
Pages: 505-16
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24421394 | J:213532
First Author: Ramakrishnan SK
Year: 2014
Journal: Mol Cell Biol
Title: Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis.
Volume: 34
Issue: 7
Pages: 1208-20
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27501247 | J:236614
First Author: Cho SH
Year: 2016
Journal: Nature
Title: Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.
Volume: 537
Issue: 7619
Pages: 234-238
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25915585 | J:222971
First Author: Usui Y
Year: 2015
Journal: J Clin Invest
Title: Neurovascular crosstalk between interneurons and capillaries is required for vision.
Volume: 125
Issue: 6
Pages: 2335-46
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27122313 | J:232188
First Author: Bouaziz W
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice.
Volume: 113
Issue: 19
Pages: 5453-8
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23114598 | J:193997
First Author: Liu Q
Year: 2012
Journal: J Clin Invest
Title: Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis.
Volume: 122
Issue: 12
Pages: 4635-44
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Publication
24891620 | J:224278
First Author: Xie L
Year: 2014
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation.
Volume: 34
Issue: 16
Pages: 3013-23
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Publication
22464323 | J:186085
First Author: Rankin EB
Year: 2012
Journal: Cell
Title: The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Volume: 149
Issue: 1
Pages: 63-74
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Publication
22869521 | J:189135
First Author: Anderson ER
Year: 2012
Journal: Mol Cell Biol
Title: The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression.
Volume: 32
Issue: 19
Pages: 4068-77
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Publication
23103253 | J:194004
First Author: Elorza A
Year: 2012
Journal: Mol Cell
Title: HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.
Volume: 48
Issue: 5
Pages: 681-91
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22086418 | J:181805
First Author: Koulnis M
Year: 2012
Journal: Blood
Title: Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways.
Volume: 119
Issue: 5
Pages: 1228-39
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Publication
22930750 | J:214713
First Author: Aro E
Year: 2012
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.
Volume: 287
Issue: 44
Pages: 37134-44
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35313689 | J:328675
First Author: Harada Y
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