Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 350 out of 350 for Xk

<< First < Previous | Next > Last >>

0.016s

Type

Details

Score

Publication

36585109 | J:357810

First Author:	Tu LF
Year:	2023
Journal:	J Adv Res
Title:	GPX4 deficiency-dependent phospholipid peroxidation drives motor deficits of ALS.
Volume:	43

Pages:	205-218

•

Publication

24780906 | J:215272

First Author:	Ardeljan D
Year:	2014
Journal:	PLoS One
Title:	Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.
Volume:	9
Issue:	4
Pages:	e95900

•

Publication

32051546 | J:291410

First Author:	Cong XX
Year:	2020
Journal:	Cell Death Differ
Title:	Rab5a activates IRS1 to coordinate IGF-AKT-mTOR signaling and myoblast differentiation during muscle regeneration.
Volume:	27
Issue:	8
Pages:	2344-2362

•

Publication

29315990 | J:261329

First Author:	Cong XX
Year:	2018
Journal:	Stem Cells
Title:	Activation of AKT-mTOR Signaling Directs Tenogenesis of Mesenchymal Stem Cells.
Volume:	36
Issue:	4
Pages:	527-539

•

Publication

37377116 | J:356202

First Author:	Zhang Y
Year:	2023
Journal:	Eur Heart J
Title:	Sirtuin 2 deficiency aggravates ageing-induced vascular remodelling in humans and mice.
Volume:	44
Issue:	29
Pages:	2746-2759

•

Publication

30275345 | J:268002

First Author:	Fan W
Year:	2018
Journal:	Mol Cell Biol
Title:	Hsp70 Interacts with Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 To Regulate p38MAPK Stability and Myoblast Differentiation during Skeletal Muscle Regeneration.
Volume:	38
Issue:	24

•

Publication

31386303 | J:295893

First Author:	Zhan S
Year:	2019
Journal:	J Cell Mol Med
Title:	Molecular mechanism of tumour necrosis factor alpha regulates hypocretin (orexin) expression, sleep and behaviour.
Volume:	23
Issue:	10
Pages:	6822-6834

•

Publication

33526512 | J:305541

First Author:	Montrose DC
Year:	2021
Journal:	Cancer Res
Title:	Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil.
Volume:	81
Issue:	9
Pages:	2275-2288

•

Publication

32961355 | J:325227

First Author:	Montrose DC
Year:	2021
Journal:	Cell Mol Gastroenterol Hepatol
Title:	Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis.
Volume:	11
Issue:	2
Pages:	525-550

•

Publication

38459023 | J:360857

First Author:	Zhang Z
Year:	2024
Journal:	Nat Commun
Title:	Deficiency of ASGR1 promotes liver injury by increasing GP73-mediated hepatic endoplasmic reticulum stress.
Volume:	15
Issue:	1
Pages:	1908

•

Publication

10438732 | -

First Author:	Lee S
Year:	1999
Journal:	Blood
Title:	Proteolytic processing of big endothelin-3 by the kell blood group protein.
Volume:	94
Issue:	4
Pages:	1440-50

•

Protein Domain

IPR029737 | KEL

Type:	Family
Description:	Kell blood group glycoprotein (KEL; MEROPS identifier M13.090) shares sequence homology with members of the M13 family of zinc-dependent metalloproteases and is part of the Kell blood group system (consists of KEL and XK) []. KEL and XK are antigens linked covalently at the surface of red blood cells []. KEL processes big endothelin-3 to generate endothelin-3 [].

•

Publication

25586376 | J:219268

First Author:	Singh SK
Year:	2015
Journal:	EMBO J
Title:	Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity.
Volume:	34
Issue:	4
Pages:	517-30

•

Publication

26347470 | J:273622

First Author:	Ridder DA
Year:	2015
Journal:	J Exp Med
Title:	Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.
Volume:	212
Issue:	10
Pages:	1529-49

•

Publication

28388439 | J:251911

First Author:	Hu M
Year:	2017
Journal:	Mol Cell
Title:	Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy.
Volume:	66
Issue:	1
Pages:	141-153.e6

•

Publication

38123537 | J:346799

First Author:	Cao J
Year:	2023
Journal:	Nat Commun
Title:	Reassessing endothelial-to-mesenchymal transition in mouse bone marrow: insights from lineage tracing models.
Volume:	14
Issue:	1
Pages:	8461

•

Publication

33500732 | J:313860

First Author:	Chen ML
Year:	2021
Journal:	Theranostics
Title:	Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.
Volume:	11
Issue:	5
Pages:	2395-2409

•

Publication

28714476 | J:249683

First Author:	Chen L
Year:	2017
Journal:	Nat Commun
Title:	Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXRα.
Volume:	8

Pages:	16066

•

Publication

35304471 | J:324882

First Author:	Wang ZX
Year:	2022
Journal:	Nat Commun
Title:	Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox.
Volume:	13
Issue:	1
Pages:	1453

•

Publication

33143524 | J:303292

First Author:	Liu ZZ
Year:	2020
Journal:	Autophagy
Title:	Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3.


Pages:	1-17

•

Publication

33321102 | J:300522

First Author:	Xie G
Year:	2020
Journal:	Dev Cell
Title:	Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability.
Volume:	55
Issue:	6
Pages:	707-722.e9

•

Publication

36812344 | J:334327

First Author:	Bhardwaj P
Year:	2023
Journal:	Sci Transl Med
Title:	Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2.
Volume:	15
Issue:	684
Pages:	eade1857

•

Publication

6614593 | J:7183

First Author:	Andersson L
Year:	1983
Journal:	Anim Blood Groups Biochem Genet
Title:	Genetic linkage between the loci for phosphohexose isomerase (PHI) and a serum protein (Xk) in horses.
Volume:	14
Issue:	1
Pages:	45-50

•

Protein

Q5GH64

Organism:	Mus musculus/domesticus
Length:	580
Fragment?:	false

•

Protein

Q5GH67

Organism:	Mus musculus/domesticus
Length:	647
Fragment?:	false

•

Protein

Q5GH68

Organism:	Mus musculus/domesticus
Length:	449
Fragment?:	false

•

Protein

Q5GH66

Organism:	Mus musculus/domesticus
Length:	676
Fragment?:	false

•

Protein

E9Q6C8

Organism:	Mus musculus/domesticus
Length:	638
Fragment?:	false

•

Protein

Q5GH62

Organism:	Mus musculus/domesticus
Length:	373
Fragment?:	false

•

Publication

23845944 | J:199440

First Author:	Suzuki J
Year:	2013
Journal:	Science
Title:	Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells.
Volume:	341
Issue:	6144
Pages:	403-6

•

Publication

28881496 | J:317385

First Author:	Kim GW
Year:	2017
Journal:	FEBS J
Title:	Xk-related protein 8 regulates myoblast differentiation and survival.
Volume:	284
Issue:	21
Pages:	3575-3588

•

Protein

Q8C0T0

Organism:	Mus musculus/domesticus
Length:	401
Fragment?:	false

•

Protein

Q8BG78

Organism:	Mus musculus/domesticus
Length:	510
Fragment?:	false

•

Protein

Q0VFY4

Organism:	Mus musculus/domesticus
Length:	510
Fragment?:	false

•

Protein

Q8C9P4

Organism:	Mus musculus/domesticus
Length:	112
Fragment?:	false

•

Protein

B2RY73

Organism:	Mus musculus/domesticus
Length:	373
Fragment?:	false

•

Protein

D6RIN5

Organism:	Mus musculus/domesticus
Length:	112
Fragment?:	false

•

Protein

H3BL12

Organism:	Mus musculus/domesticus
Length:	92
Fragment?:	true

•

Protein

H3BJG3

Organism:	Mus musculus/domesticus
Length:	209
Fragment?:	true

•

Protein

Q059K7

Organism:	Mus musculus/domesticus
Length:	446
Fragment?:	false

•

Publication

8004674 | -

First Author:	Ho M
Year:	1994
Journal:	Cell
Title:	Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein.
Volume:	77
Issue:	6
Pages:	869-80

•

Publication

7737196 | -

First Author:	Khamlichi S
Year:	1995
Journal:	Eur J Biochem
Title:	Purification and partial characterization of the erythrocyte Kx protein deficient in McLeod patients.
Volume:	228
Issue:	3
Pages:	931-4

•

Protein Domain

IPR018629 | XK-rel

Type:

Family

Description:

This family is represented by the multipass membrane protein XK, which may be involved in sodium-dependent transport of neutral amino acids or oligopeptides. It forms a heterodimer with Kell. In humans, Kell is an 93kDa type II membrane glycoprotein with endothelin-3-converting enzyme activity that is linked by a single disulphide bond to XK, that spans the membrane ten times. An absence of XK leads to clinical symptoms termed the McLeod syndrome , an X-linked multi-system disorder characterised by late onset abnormalities in the neuromuscular and hematopoietic systems [, ]. It has been shown that XK recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane and dysregulation of a VPS13A-XK complex is the common basis for Chorea-Acanthocytosis and McLeod Syndrome []. The human and mouse Xk-related (Xkr) families consist of nine and eight members, respectively, and mutations or variations in the gene of Xkr members are associated to human diseases. Xkr8 and other members of the family promote phosphatidylserine exposure in apoptotic cells [, , ].

•

Publication

31712393 | J:293092

First Author:	Yamashita Y
Year:	2020
Journal:	Mol Cell Biol
Title:	Infertility Caused by Inefficient Apoptotic Germ Cell Clearance in Xkr8-Deficient Male Mice.
Volume:	40
Issue:	3

•

Publication

23179721 | J:323239

First Author:	Bunker RD
Year:	2013
Journal:	J Biol Chem
Title:	Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism.
Volume:	288
Issue:	3
Pages:	1643-52

•

Publication

19544475 | J:212529

First Author:	Zhu X
Year:	2009
Journal:	Am J Hematol
Title:	Changes in red cell ion transport, reduced intratumoral neovascularization, and some mild motor function abnormalities accompany targeted disruption of the Mouse Kell gene (Kel).
Volume:	84
Issue:	8
Pages:	492-8

•

Protein

A0A0A6YXM8

Organism:	Mus musculus/domesticus
Length:	69
Fragment?:	true

•

Protein

Q9EQF2

Organism:	Mus musculus/domesticus
Length:	713
Fragment?:	false

•

Protein

A0A0A6YVT2

Organism:	Mus musculus/domesticus
Length:	286
Fragment?:	true

•

Publication

16141072 | J:99680

First Author:	Carninci P
Year:	2005
Journal:	Science
Title:	The transcriptional landscape of the mammalian genome.
Volume:	309
Issue:	5740
Pages:	1559-63

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=300&searchTerm=Xk

MouseMine

Search our database by keyword

Examples

Search results 301 to 350 out of 350 for Xk

Categories

Hits by Pathway

Hits by Category

Hits by Strain