| Type |
Details |
Score |
| Allele |
| Name: |
G protein-coupled receptor 68; targeted mutation 1.1, Akihiro Harada |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 535, Ruslan Medzhitov |
| Allele Type: |
Transgenic |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
beclin 1, autophagy related; targeted mutation 2.1, Beth Levine |
| Allele Type: |
Targeted |
| Attribute String: |
Constitutively active |
|
•
•
•
•
•
|
| Allele |
| Name: |
alcohol dehydrogenase, iron containing, 1; transposon insertion IR3.PV404, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
AF4/FMR2 family, member 3; transposon insertion IR3.PV516, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Allele |
| Name: |
adhesion G protein-coupled receptor B3; transposon insertion PV449, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
coiled-coil domain containing 3; transposon insertion PV449, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
myeloid-associated differentiation marker; transposon insertion PV324, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4; transposon insertion PV630, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
RAD54 like 2 (S. cerevisiae); transposon insertion PV405, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
single-stranded DNA binding protein 2; transposon insertion PV486, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
syntaxin 3; transposon insertion PV579, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transmembrane protein 117; transposon insertion PV416, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
zinc finger protein 326; transposon insertion PV484, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transposon insertion PV250, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transposon insertion PV372, Junji Takeda |
| Allele Type: |
Transposon induced |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fnip1/Fnip1 Tg(BCL2)22Wehi/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Caucheteux SM |
| Year: |
2005 |
| Journal: |
Int Immunol |
| Title: |
Pregnancy-induced alterations of B cell maturation and survival are differentially affected by Fas and Bcl-2, independently of BcR expression. |
| Volume: |
17 |
| Issue: |
1 |
| Pages: |
55-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ota T |
| Year: |
2008 |
| Journal: |
Int Immunol |
| Title: |
Autoreactive B-cell elimination by pathogenic IgG specific for the same antigen: implications for peripheral tolerance. |
| Volume: |
20 |
| Issue: |
10 |
| Pages: |
1351-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stohl W |
| Year: |
2020 |
| Journal: |
J Immunol |
| Title: |
Promotion of T Regulatory Cells in Mice by B Cells and BAFF. |
| Volume: |
204 |
| Issue: |
9 |
| Pages: |
2416-2428 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iglesias M |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Selective Impairment of TH17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T Lymphocytes. |
| Volume: |
11 |
| Issue: |
7 |
| Pages: |
e0159714 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun B |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
Sox4 is required for the survival of pro-B cells. |
| Volume: |
190 |
| Issue: |
5 |
| Pages: |
2080-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sitte S |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression. |
| Volume: |
188 |
| Issue: |
6 |
| Pages: |
2677-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Daffis S |
| Year: |
2010 |
| Journal: |
Nature |
| Title: |
2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. |
| Volume: |
468 |
| Issue: |
7322 |
| Pages: |
452-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saitoh T |
| Year: |
2011 |
| Journal: |
Immunity |
| Title: |
Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells. |
| Volume: |
34 |
| Issue: |
3 |
| Pages: |
352-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gong W |
| Year: |
2015 |
| Journal: |
J Biol Chem |
| Title: |
Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex. |
| Volume: |
290 |
| Issue: |
24 |
| Pages: |
15350-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dolfi DV |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Dendritic cells and CD28 costimulation are required to sustain virus-specific CD8+ T cell responses during the effector phase in vivo. |
| Volume: |
186 |
| Issue: |
8 |
| Pages: |
4599-608 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Unterholzner L |
| Year: |
2010 |
| Journal: |
Nat Immunol |
| Title: |
IFI16 is an innate immune sensor for intracellular DNA. |
| Volume: |
11 |
| Issue: |
11 |
| Pages: |
997-1004 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiong X |
| Year: |
2014 |
| Journal: |
Elife |
| Title: |
Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis. |
| Volume: |
3 |
|
| Pages: |
e02236 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kon N |
| Year: |
2011 |
| Journal: |
Cell Death Differ |
| Title: |
Roles of HAUSP-mediated p53 regulation in central nervous system development. |
| Volume: |
18 |
| Issue: |
8 |
| Pages: |
1366-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang J |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication. |
| Volume: |
185 |
| Issue: |
3 |
| Pages: |
1720-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xing Y |
| Year: |
2016 |
| Journal: |
Nat Immunol |
| Title: |
Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling. |
| Volume: |
17 |
| Issue: |
5 |
| Pages: |
565-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Velázquez P |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
Villous B cells of the small intestine are specialized for invariant NK T cell dependence. |
| Volume: |
180 |
| Issue: |
7 |
| Pages: |
4629-38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chang EY |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
Cutting edge: involvement of the type I IFN production and signaling pathway in lipopolysaccharide-induced IL-10 production. |
| Volume: |
178 |
| Issue: |
11 |
| Pages: |
6705-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Imai Y |
| Year: |
2008 |
| Journal: |
Cell |
| Title: |
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. |
| Volume: |
133 |
| Issue: |
2 |
| Pages: |
235-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Temizoz B |
| Year: |
2015 |
| Journal: |
Eur J Immunol |
| Title: |
TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN. |
| Volume: |
45 |
| Issue: |
4 |
| Pages: |
1159-69 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dietrich N |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
Murine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments. |
| Volume: |
5 |
| Issue: |
4 |
| Pages: |
e10250 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Humpton TJ |
| Year: |
2021 |
| Journal: |
Genes Dev |
| Title: |
Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice. |
| Volume: |
35 |
| Issue: |
1-2 |
| Pages: |
117-132 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu Z |
| Year: |
2014 |
| Journal: |
Nat Commun |
| Title: |
Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity. |
| Volume: |
5 |
|
| Pages: |
3463 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen S |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation. |
| Volume: |
181 |
| Issue: |
10 |
| Pages: |
7186-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chessler AD |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts. |
| Volume: |
181 |
| Issue: |
11 |
| Pages: |
7917-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yount JS |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai Virus defective interfering particles. |
| Volume: |
180 |
| Issue: |
7 |
| Pages: |
4910-8 |
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•
•
•
•
|
| Publication |
| First Author: |
Rongvaux A |
| Year: |
2014 |
| Journal: |
Cell |
| Title: |
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. |
| Volume: |
159 |
| Issue: |
7 |
| Pages: |
1563-77 |
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•
•
•
•
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| Publication |
| First Author: |
Van den Ackerveken P |
| Year: |
2017 |
| Journal: |
Cell Death Differ |
| Title: |
The miR-183/ItgA3 axis is a key regulator of prosensory area during early inner ear development. |
| Volume: |
24 |
| Issue: |
12 |
| Pages: |
2054-2065 |
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•
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| Publication |
| First Author: |
Ma F |
| Year: |
2015 |
| Journal: |
EMBO Rep |
| Title: |
Positive feedback regulation of type I interferon by the interferon-stimulated gene STING. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
202-12 |
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•
•
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| Publication |
| First Author: |
Kobayashi H |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
71-84 |
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•
•
•
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| Publication |
| First Author: |
Lazear HM |
| Year: |
2013 |
| Journal: |
PLoS Pathog |
| Title: |
IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1003118 |
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•
•
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| Publication |
| First Author: |
Mukherjee P |
| Year: |
2013 |
| Journal: |
Immunity |
| Title: |
Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death. |
| Volume: |
38 |
| Issue: |
4 |
| Pages: |
705-16 |
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•
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| First Author: |
del Fresno C |
| Year: |
2013 |
| Journal: |
Immunity |
| Title: |
Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans. |
| Volume: |
38 |
| Issue: |
6 |
| Pages: |
1176-86 |
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•
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| First Author: |
Wang J |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Effective and lesion-free cutaneous influenza vaccination. |
| Volume: |
112 |
| Issue: |
16 |
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5005-10 |
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•
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| First Author: |
Kamran N |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Toll-like receptor ligands induce expression of the costimulatory molecule CD155 on antigen-presenting cells. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
e54406 |
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•
•
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| Publication |
| First Author: |
Taylor KG |
| Year: |
2014 |
| Journal: |
J Virol |
| Title: |
Age-dependent myeloid dendritic cell responses mediate resistance to la crosse virus-induced neurological disease. |
| Volume: |
88 |
| Issue: |
19 |
| Pages: |
11070-9 |
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•
•
•
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| Publication |
| First Author: |
You F |
| Year: |
2013 |
| Journal: |
Nat Immunol |
| Title: |
ELF4 is critical for induction of type I interferon and the host antiviral response. |
| Volume: |
14 |
| Issue: |
12 |
| Pages: |
1237-46 |
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•
•
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| Publication |
| First Author: |
Negishi H |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis. |
| Volume: |
110 |
| Issue: |
49 |
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| First Author: |
Sander LE |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
385-9 |
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•
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| First Author: |
Ono C |
| Year: |
2014 |
| Journal: |
J Virol |
| Title: |
Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells. |
| Volume: |
88 |
| Issue: |
4 |
| Pages: |
2157-67 |
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•
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| First Author: |
Okabe Y |
| Year: |
2008 |
| Journal: |
Eur J Immunol |
| Title: |
IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation. |
| Volume: |
38 |
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11 |
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Migliorini D |
| Year: |
2011 |
| Journal: |
J Clin Invest |
| Title: |
Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice. |
| Volume: |
121 |
| Issue: |
4 |
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•
•
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| First Author: |
Taniguchi Y |
| Year: |
2017 |
| Journal: |
Arthritis Rheumatol |
| Title: |
Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63. |
| Volume: |
69 |
| Issue: |
3 |
| Pages: |
598-609 |
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•
•
•
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| First Author: |
Lin X |
| Year: |
2024 |
| Journal: |
Mol Cell |
| Title: |
Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts. |
| Volume: |
84 |
| Issue: |
20 |
| Pages: |
3916-3931.e7 |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE7020 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
E-GEOD-38741 |
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
E-GEOD-79035 |
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiang Z |
| Year: |
2010 |
| Journal: |
J Clin Invest |
| Title: |
Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia. |
| Volume: |
120 |
| Issue: |
6 |
| Pages: |
2109-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Djajawi TM |
| Year: |
2020 |
| Journal: |
Cell Death Differ |
| Title: |
MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex. |
| Volume: |
27 |
| Issue: |
8 |
| Pages: |
2484-2499 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fernandes R |
| Year: |
2012 |
| Journal: |
Biol Reprod |
| Title: |
NLRP5 mediates mitochondrial function in mouse oocytes and embryos. |
| Volume: |
86 |
| Issue: |
5 |
| Pages: |
138, 1-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hanson CH |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
CD62L expression marks a functionally distinct subset of memory B cells. |
| Volume: |
42 |
| Issue: |
12 |
| Pages: |
113542 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brescia P |
| Year: |
2018 |
| Journal: |
Cancer Cell |
| Title: |
MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis. |
| Volume: |
34 |
| Issue: |
3 |
| Pages: |
453-465.e9 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
333
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
51
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chakraborty M |
| Year: |
2001 |
| Journal: |
Cancer Res |
| Title: |
Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression. |
| Volume: |
61 |
| Issue: |
19 |
| Pages: |
7255-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Johnstone RW |
| Year: |
1996 |
| Journal: |
Mol Cell Biol |
| Title: |
A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1. |
| Volume: |
16 |
| Issue: |
12 |
| Pages: |
6945-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie J |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
PAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor protein. |
| Volume: |
280 |
| Issue: |
14 |
| Pages: |
13824-32 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Prostate apoptosis response 4 (Par-4) induced apoptosis of selective prostate cancer cells PC-3, DU-145, and TSU-Pr and caused tumor regression by inhibition of NF-kappaB activity and cell membrane trafficking of Fas and FasL that leads to the activation of the Fas-Fas-associated death domain-caspase-8 pro-death pathway []. It modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1. It down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1 []. Par-4 also regulates the amyloid precursor protein (APP) cleavage activity of BACE1 []. |
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•
•
•
•
|
| Publication |
| First Author: |
Healy ME |
| Year: |
2020 |
| Journal: |
Gastroenterology |
| Title: |
MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice. |
| Volume: |
159 |
| Issue: |
1 |
| Pages: |
183-199 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wakatsuki S |
| Year: |
2017 |
| Journal: |
J Cell Biol |
| Title: |
GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. |
| Volume: |
216 |
| Issue: |
2 |
| Pages: |
477-493 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weng SY |
| Year: |
2011 |
| Journal: |
J Hepatol |
| Title: |
Synergism between p53 and Mcl-1 in protecting from hepatic injury, fibrosis and cancer. |
| Volume: |
54 |
| Issue: |
4 |
| Pages: |
685-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Landsman L |
| Year: |
2009 |
| Journal: |
Blood |
| Title: |
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. |
| Volume: |
113 |
| Issue: |
4 |
| Pages: |
963-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jensen CT |
| Year: |
2008 |
| Journal: |
Blood |
| Title: |
Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development. |
| Volume: |
111 |
| Issue: |
4 |
| Pages: |
2083-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Simon DJ |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
A caspase cascade regulating developmental axon degeneration. |
| Volume: |
32 |
| Issue: |
49 |
| Pages: |
17540-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jackson JT |
| Year: |
2020 |
| Journal: |
Eur J Immunol |
| Title: |
Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a. |
| Volume: |
50 |
| Issue: |
7 |
| Pages: |
959-971 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Knittel G |
| Year: |
2016 |
| Journal: |
Blood |
| Title: |
B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice. |
| Volume: |
127 |
| Issue: |
22 |
| Pages: |
2732-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Müller L |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
The corepressor NCOR1 regulates the survival of single-positive thymocytes. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
15928 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niebuhr B |
| Year: |
2013 |
| Journal: |
Blood |
| Title: |
Runx1 is essential at two stages of early murine B-cell development. |
| Volume: |
122 |
| Issue: |
3 |
| Pages: |
413-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Palmer VL |
| Year: |
2015 |
| Journal: |
J Immunol |
| Title: |
VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection. |
| Volume: |
195 |
| Issue: |
4 |
| Pages: |
1524-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coffre M |
| Year: |
2016 |
| Journal: |
Cell Rep |
| Title: |
miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during BÂ Cell Maturation. |
| Volume: |
17 |
| Issue: |
9 |
| Pages: |
2271-2285 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Burger ML |
| Year: |
2014 |
| Journal: |
Elife |
| Title: |
T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity. |
| Volume: |
3 |
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
237
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
235
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
193
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
204
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walter L |
| Year: |
1995 |
| Journal: |
Genomics |
| Title: |
Identification of a novel conserved human gene, TEGT. |
| Volume: |
28 |
| Issue: |
2 |
| Pages: |
301-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Albu DI |
| Year: |
2007 |
| Journal: |
J Exp Med |
| Title: |
BCL11B is required for positive selection and survival of double-positive thymocytes. |
| Volume: |
204 |
| Issue: |
12 |
| Pages: |
3003-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brady BL |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks. |
| Volume: |
190 |
| Issue: |
7 |
| Pages: |
3256-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tam H |
| Year: |
2024 |
| Journal: |
J Exp Med |
| Title: |
Phosphatidylserine phospholipase A1 enables GPR34-dependent immune cell accumulation in the peritoneal cavity. |
| Volume: |
221 |
| Issue: |
11 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Campbell KJ |
| Year: |
2012 |
| Journal: |
Cell Death Differ |
| Title: |
Elevated Mcl-1 inhibits thymocyte apoptosis and alters thymic selection. |
| Volume: |
19 |
| Issue: |
12 |
| Pages: |
1962-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Turnis ME |
| Year: |
2021 |
| Journal: |
Blood |
| Title: |
Requirement for antiapoptotic MCL-1 during early erythropoiesis. |
| Volume: |
137 |
| Issue: |
14 |
| Pages: |
1945-1958 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lassot I |
| Year: |
2010 |
| Journal: |
Cell Death Differ |
| Title: |
Trim17, a novel E3 ubiquitin-ligase, initiates neuronal apoptosis. |
| Volume: |
17 |
| Issue: |
12 |
| Pages: |
1928-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wilkinson B |
| Year: |
2001 |
| Journal: |
Cell Immunol |
| Title: |
Requirement for sustained MAPK signaling in both CD4 and CD8 lineage commitment: a threshold model. |
| Volume: |
211 |
| Issue: |
2 |
| Pages: |
86-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Selimi F |
| Year: |
2000 |
| Journal: |
J Neurosci |
| Title: |
Bax inactivation in lurcher mutants rescues cerebellar granule cells but not purkinje cells or inferior olivary neurons. |
| Volume: |
20 |
| Issue: |
14 |
| Pages: |
5339-45 |
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•
•
•
•
|