|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 3001 to 3100 out of 3175 for Mapt

<< First    < Previous  |  Next >    Last >>
0.032s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
35401818 | J:387077
First Author: Tao R
Year: 2022
Journal: Theranostics
Title: High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease.
Volume: 12
Issue: 6
Pages: 2549-2559
•
•
•
•
•
Publication
40773679 | J:372685
First Author: Kassir MF
Year: 2025
Journal: Cancer Res
Title: Alzheimer's Disease-Associated Amyloid-? Precursor Protein Prevents Aging Stress-Induced Mitophagy and Fumarate Depletion to Improve Antitumor Immunity.
Volume: 85
Issue: 19
Pages: 3791-3811
•
•
•
•
•
Publication
34850492 | J:353175
First Author: Nguyen P
Year: 2022
Journal: Microsc Res Tech
Title: An easy brain thick-section-clearing protocol to observe antigens in the brains of neurological disease mouse models by conventional epifluorescence and confocal laser scanning microscopy.
Volume: 85
Issue: 4
Pages: 1618-1626
•
•
•
•
•
Publication
41987289 | J:387102
 
First Author: Yang L
Year: 2026
Journal: Mol Neurodegener
Title: Obesity-driven phosphatidylethanolamine dysregulation impairs neuroimmune crosstalk and accelerates Alzheimer's pathogenesis.
Volume: 21
Issue: 1
•
•
•
•
•
Publication
38750512 | J:352622
First Author: Zhang N
Year: 2024
Journal: Alzheimers Res Ther
Title: Cholecystokinin B receptor agonists alleviates anterograde amnesia in cholecystokinin-deficient and aged Alzheimer's disease mice.
Volume: 16
Issue: 1
Pages: 109
•
•
•
•
•
Publication
40007341 | J:363865
 
First Author: Han X
Year: 2025
Journal: Phytomedicine
Title: Lycium barbarum extract improves brain and visual functions in mice models of Alzheimer's disease through activating WNT pathway.
Volume: 139
Pages: 156523
•
•
•
•
•
Publication
36254251 | J:352636
First Author: Yu H
Year: 2022
Journal: MedComm (2020)
Title: Integrated analyses of brain and platelet omics reveal their common altered and driven molecules in Alzheimer's disease.
Volume: 3
Issue: 4
Pages: e180
•
•
•
•
•
Publication
27155503 | J:242424
First Author: Hargis KE
Year: 2017
Journal: Behav Brain Res
Title: Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?
Volume: 322
Issue: Pt B
Pages: 311-328
•
•
•
•
•
Publication
39394468 | J:358361
First Author: Guo Y
Year: 2024
Journal: EMBO Mol Med
Title: Targeting USP11 regulation by a novel lithium-organic coordination compound improves neuropathologies and cognitive functions in Alzheimer transgenic mice.
Volume: 16
Issue: 11
Pages: 2856-2881
•
•
•
•
•
Publication
33893290 | J:304519
First Author: Baglietto-Vargas D
Year: 2021
Journal: Nat Commun
Title: Generation of a humanized A? expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Volume: 12
Issue: 1
Pages: 2421
•
•
•
•
•
Publication
32920368 | J:348446
 
First Author: Danielyan L
Year: 2020
Journal: EBioMedicine
Title: Cell motility and migration as determinants of stem cell efficacy.
Volume: 60
Pages: 102989
•
•
•
•
•
Publication
31164420 | J:279242
First Author: Bahn G
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.
Volume: 116
Issue: 25
Pages: 12516-12523
•
•
•
•
•
Publication
37421950 | J:339320
First Author: Xiang J
Year: 2023
Journal: Cell
Title: Development of an ?-synuclein positron emission tomography tracer for imaging synucleinopathies.
Volume: 186
Issue: 16
Pages: 3350-3367.e19
•
•
•
•
•
Publication
22367970 | J:183771
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Volume: 21
Issue: 11
Pages: 2538-47
•
•
•
•
•
Publication
29018038 | J:248850
First Author: Pera M
Year: 2017
Journal: EMBO J
Title: Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease.
Volume: 36
Issue: 22
Pages: 3356-3371
•
•
•
•
•
Publication
37298502 | J:348455
 
First Author: Choi Y
Year: 2023
Journal: Int J Mol Sci
Title: Capacitive Electrode-Based Electric Field Treatments on Redox-Toxic Iron Deposits in Transgenic AD Mouse Models: The Electroceutical Targeting of Alzheimer's Disease Feasibility Study.
Volume: 24
Issue: 11
•
•
•
•
•
Publication
36451854 | J:348479
First Author: Yang H
Year: 2022
Journal: Theranostics
Title: Adoptive therapy with amyloid-? specific regulatory T cells alleviates Alzheimer's disease.
Volume: 12
Issue: 18
Pages: 7668-7680
•
•
•
•
•
Publication
33902708 | J:348523
First Author: Park JS
Year: 2021
Journal: Acta Neuropathol Commun
Title: Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 78
•
•
•
•
•
Publication
27470171 | J:236530
First Author: H?fling C
Year: 2016
Journal: Aging Cell
Title: Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.
Volume: 15
Issue: 5
Pages: 953-63
•
•
•
•
•
Publication
36703981 | J:355400
 
First Author: Daini E
Year: 2022
Journal: Front Immunol
Title: Melanocortin receptor agonist NDP-?-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice.
Volume: 13
Pages: 1082036
•
•
•
•
•
Publication
26214837 | J:228830
First Author: Zenaro E
Year: 2015
Journal: Nat Med
Title: Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin.
Volume: 21
Issue: 8
Pages: 880-6
•
•
•
•
•
Publication
38117656 | J:355509
First Author: Xiang J
Year: 2024
Journal: STAR Protoc
Title: Protocol for screening ?-synuclein PET tracer candidates in?vitro and ex?vivo.
Volume: 5
Issue: 1
Pages: 102788
•
•
•
•
•
Publication
42372723 | J:389148
First Author: Tyagi M
Year: 2026
Journal: Cell
Title: Arc mediates intercellular tau transmission via extracellular vesicles.
Volume: 189
Issue: 15
Pages: 4706-4723.e13
•
•
•
•
•
Publication
31858697 | J:358332
First Author: Song JX
Year: 2020
Journal: Aging Cell
Title: A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.
Volume: 19
Issue: 2
Pages: e13069
•
•
•
•
•
Publication
29501742 | J:273677
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
Volume: 498
Issue: 1
Pages: 234-239
•
•
•
•
•
Publication
18800967 | J:141307
First Author: Ribe EM
Year: 2008
Journal: Biochem J
Title: Mechanisms of neuronal death in disease: defining the models and the players.
Volume: 415
Issue: 2
Pages: 165-82
•
•
•
•
•
Publication
36843263 | J:338361
First Author: Kim SH
Year: 2023
Journal: Autophagy
Title: Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease.
Volume: 19
Issue: 8
Pages: 2318-2337
•
•
•
•
•
Publication
28972160 | J:368273
First Author: Boselli M
Year: 2017
Journal: J Biol Chem
Title: An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.
Volume: 292
Issue: 47
Pages: 19209-19225
•
•
•
•
•
Publication
22778846 | J:368534
First Author: Crowe SE
Year: 2010
Journal: ACS Chem Neurosci
Title: Photochemically initiated intracellular astrocytic calcium waves in living mice using two-photon uncaging of IP(3).
Volume: 1
Issue: 8
Pages: 575-85
•
•
•
•
•
Publication
38906984 | J:350176
First Author: Jong Huat T
Year: 2024
Journal: Sci Rep
Title: The impact of astrocytic NF-?B on healthy and Alzheimer's disease brains.
Volume: 14
Issue: 1
Pages: 14305
•
•
•
•
•
Publication
34166772 | J:368419
 
First Author: Xia Y
Year: 2021
Journal: Prog Neurobiol
Title: Delta- and beta- secretases crosstalk amplifies the amyloidogenic pathway in Alzheimer's disease.
Volume: 204
Pages: 102113
•
•
•
•
•
Publication
29560732 | J:368279
First Author: Habib A
Year: 2018
Journal: Cell Transplant
Title: Human Umbilical Cord Blood Serum-derived ?-Secretase: Functional Testing in Alzheimer's Disease Mouse Models.
Volume: 27
Issue: 3
Pages: 438-455
•
•
•
•
•
Publication
40677154 | J:371916
First Author: Barnett AM
Year: 2025
Journal: Alzheimers Dement
Title: Loss of lysosomal acid lipase contributes to Alzheimer's disease pathology and cognitive decline.
Volume: 21
Issue: 7
Pages: e70486
•
•
•
•
•
Publication
38555992 | J:351247
 
First Author: Wang J
Year: 2024
Journal: Brain Behav Immun
Title: A TrkB cleavage fragment in hippocampus promotes Depressive-Like behavior in mice.
Volume: 119
Pages: 56-83
•
•
•
•
•
Publication
20305648 | J:159680
First Author: Fuhrmann M
Year: 2010
Journal: Nat Neurosci
Title: Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.
Volume: 13
Issue: 4
Pages: 411-3
•
•
•
•
•
Publication
18021291 | J:141555
First Author: Lopez JR
Year: 2008
Journal: J Neurochem
Title: Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.
Volume: 105
Issue: 1
Pages: 262-71
•
•
•
•
•
Publication
37308288 | J:337909
 
First Author: Sanna PP
Year: 2023
Journal: eNeuro
Title: A History of Repeated Alcohol Intoxication Promotes Cognitive Impairment and Gene Expression Signatures of Disease Progression in the 3xTg Mouse Model of Alzheimer's Disease.
Volume: 10
Issue: 7
•
•
•
•
•
Publication
21235806 | J:194454
First Author: Fonseca MI
Year: 2011
Journal: J Neuroinflammation
Title: Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 4
•
•
•
•
•
Publication
37409006 | J:346956
 
First Author: Weigel TK
Year: 2023
Journal: Front Aging Neurosci
Title: Altered circadian behavior and light sensing in mouse models of Alzheimer's disease.
Volume: 15
Pages: 1218193
•
•
•
•
•
Publication
32832679 | J:327386
First Author: Chen C
Year: 2020
Journal: Sci Adv
Title: Gut dysbiosis contributes to amyloid pathology, associated with C/EBP?/AEP signaling activation in Alzheimer's disease mouse model.
Volume: 6
Issue: 31
Pages: eaba0466
•
•
•
•
•
Publication
25447943 | J:231418
 
First Author: Hohsfield LA
Year: 2014
Journal: Mol Cell Neurosci
Title: Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models.
Volume: 63
Pages: 83-95
•
•
•
•
•
Publication
37714422 | J:386901
 
First Author: Miao J
Year: 2023
Journal: Brain Res
Title: 40??Hz Electroacupuncture relieves the memory dysfunction of 5xFAD mice by regulating neuronal electrical activity.
Volume: 1821
Pages: 148576
•
•
•
•
•
Publication
38365740 | J:386906
First Author: Wang M
Year: 2024
Journal: Nat Commun
Title: Non-invasive modulation of meningeal lymphatics ameliorates ageing and Alzheimer's disease-associated pathology and cognition in mice.
Volume: 15
Issue: 1
Pages: 1453
•
•
•
•
•
Publication
30635592 | J:275422
First Author: Creighton SD
Year: 2019
Journal: Sci Rep
Title: Dissociable cognitive impairments in two strains of transgenic Alzheimer's disease mice revealed by a battery of object-based tests.
Volume: 9
Issue: 1
Pages: 57
•
•
•
•
•
Publication
23955714 | J:202038
First Author: Pietri M
Year: 2013
Journal: Nat Med
Title: PDK1 decreases TACE-mediated ?-secretase activity and promotes disease progression in prion and Alzheimer's diseases.
Volume: 19
Issue: 9
Pages: 1124-31
•
•
•
•
•
Publication
39934151 | J:367799
First Author: Yarbro JM
Year: 2025
Journal: Nat Commun
Title: Human and mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome.
Volume: 16
Issue: 1
Pages: 1533
•
•
•
•
•
Publication
36387280 | J:368896
 
First Author: Sreenivasmurthy SG
Year: 2022
Journal: Front Mol Biosci
Title: Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer's disease therapy.
Volume: 9
Pages: 1030534
•
•
•
•
•
Publication
33339957 | J:368819
First Author: Xia Y
Year: 2021
Journal: Mol Psychiatry
Title: C/EBP? is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer's disease.
Volume: 26
Issue: 10
Pages: 6002-6022
•
•
•
•
•
Publication
35286997 | J:386875
 
First Author: Iyaswamy A
Year: 2022
Journal: Redox Biol
Title: Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models.
Volume: 51
Pages: 102280
•
•
•
•
•
Publication
40146773 | J:366264
First Author: Wilson P
Year: 2025
Journal: Cell Rep
Title: Presynaptic recycling pool density regulates spontaneous synaptic vesicle exocytosis rate and is upregulated in the presence of ?-amyloid.
Volume: 44
Issue: 4
Pages: 115410
•
•
•
•
•
Publication
41510572 | J:388101
First Author: Tang C
Year: 2026
Journal: Adv Mater
Title: Synthetic Disaggregators Enhance Central-Peripheral Amyloid-?? Clearance in Alzheimer's Disease.
Volume: 38
Issue: 11
Pages: e20002
•
•
•
•
•
Publication
21704011 | J:174403
First Author: Medeiros R
Year: 2011
Journal: Am J Pathol
Title: Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline.
Volume: 179
Issue: 2
Pages: 980-91
•
•
•
•
•
Publication
21829458 | J:284814
First Author: Bianchi FT
Year: 2011
Journal: PLoS One
Title: The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.
Volume: 6
Issue: 7
Pages: e22370
•
•
•
•
•
Publication
28826672 | J:271996
First Author: Wang ZH
Year: 2017
Journal: Mol Cell
Title: Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.
Volume: 67
Issue: 5
Pages: 812-825.e5
•
•
•
•
•
Publication
26969629 | J:351702
First Author: Roddick KM
Year: 2016
Journal: Chem Senses
Title: Sex and Genotype Differences in Odor Detection in the 3?Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age.
Volume: 41
Issue: 5
Pages: 433-40
•
•
•
•
•
Publication
34522902 | J:359101
First Author: Heged?s P
Year: 2021
Journal: STAR Protoc
Title: Training protocol for probabilistic Pavlovian conditioning in mice using an open-source head-fixed setup.
Volume: 2
Issue: 3
Pages: 100795
•
•
•
•
•
Publication
29725016 | J:262986
First Author: Wang ZH
Year: 2018
Journal: Nat Commun
Title: C/EBP? regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 1784
•
•
•
•
•
Publication
42152074 | J:388160
 
First Author: Erisir A
Year: 2026
Journal: Acta Neuropathol Commun
Title: Dysregulated oligodendrocyte and myelin dynamics as an early pathological feature of neuropil degeneration in Alzheimer's disease: an ultrastructural study.
Volume: 14
Issue: 1
•
•
•
•
•
Publication
35198070 | J:327457
First Author: Cai CZ
Year: 2022
Journal: Theranostics
Title: Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models.
Volume: 12
Issue: 4
Pages: 1738-1755
•
•
•
•
•
Publication
25947203 | J:351760
First Author: Plagg B
Year: 2015
Journal: Biogerontology
Title: Platelet dysfunction in hypercholesterolemia mice, two Alzheimer's disease mouse models and in human patients with Alzheimer's disease.
Volume: 16
Issue: 4
Pages: 543-58
•
•
•
•
•
Publication
39110781 | J:353793
First Author: Han J
Year: 2024
Journal: Sci Transl Med
Title: Engineered exosomes with a photoinducible protein delivery system enable CRISPR-Cas-based epigenome editing in Alzheimer's disease.
Volume: 16
Issue: 759
Pages: eadi4830
•
•
•
•
•
Publication
36529803 | J:370686
First Author: Tan Z
Year: 2022
Journal: Acta Neuropathol Commun
Title: Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer's disease.
Volume: 10
Issue: 1
Pages: 182
•
•
•
•
•
Publication
22926141 | J:188922
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Volume: 21
Issue: 23
Pages: 5131-46
•
•
•
•
•
Publication
27605009 | J:353702
First Author: Qin Y
Year: 2016
Journal: J Immunol
Title: Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice.
Volume: 197
Issue: 8
Pages: 3281-3292
•
•
•
•
•
Publication
37117599 | J:339502
First Author: March-Diaz R
Year: 2021
Journal: Nat Aging
Title: Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Volume: 1
Issue: 4
Pages: 385-399
•
•
•
•
•
Publication
38526616 | J:347931
First Author: Edwards GA 3rd
Year: 2024
Journal: Acta Neuropathol
Title: TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy.
Volume: 147
Issue: 1
Pages: 61
•
•
•
•
•
Publication
31852801 | J:283511
 
First Author: Wheeler JM
Year: 2019
Journal: Sci Transl Med
Title: Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.
Volume: 11
Issue: 523
•
•
•
•
•
Publication
33891876 | J:306299
First Author: Bourdenx M
Year: 2021
Journal: Cell
Title: Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Volume: 184
Issue: 10
Pages: 2696-2714.e25
•
•
•
•
•
Publication
31076275 | J:276144
First Author: Adaikkan C
Year: 2019
Journal: Neuron
Title: Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection.
Volume: 102
Issue: 5
Pages: 929-943.e8
•
•
•
•
•
Publication
40300603 | J:369831
First Author: Harris SS
Year: 2025
Journal: Cell
Title: Alzheimer's disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons.
Volume: 188
Issue: 14
Pages: 3775-3788.e21
•
•
•
•
•
Publication
40945514 | J:373754
First Author: Croce KR
Year: 2025
Journal: Neuron
Title: A rare genetic variant confers resistance to neurodegeneration across multiple neurological disorders by augmenting selective autophagy.
Volume: 113
Issue: 22
Pages: 3780-3797.e7
•
•
•
•
•
Publication
37315555 | J:339356
First Author: Sheehan PW
Year: 2023
Journal: Neuron
Title: An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Volume: 111
Issue: 15
Pages: 2383-2398.e7
•
•
•
•
•
Publication
28814543 | J:250614
 
First Author: Le Pichon CE
Year: 2017
Journal: Sci Transl Med
Title: Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Volume: 9
Issue: 403
•
•
•
•
•
Publication
37988169 | J:344400
 
First Author: Siew JJ
Year: 2024
Journal: J Clin Invest
Title: Galectin-3 aggravates microglial activation and tau transmission in tauopathy.
Volume: 134
Issue: 2
•
•
•
•
•
Publication
39719704 | J:361768
First Author: Flury A
Year: 2025
Journal: Neuron
Title: A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion.
Volume: 113
Issue: 4
Pages: 554-571.e14
•
•
•
•
•
Publication
39059388 | J:365665
First Author: Scheiblich H
Year: 2024
Journal: Neuron
Title: Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes.
Volume: 112
Issue: 18
Pages: 3106-3125.e8
•
•
•
•
•
Publication
40966081 | J:374670
First Author: Mart?n-?vila A
Year: 2025
Journal: Cell Rep
Title: Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice.
Volume: 44
Issue: 10
Pages: 116291
•
•
•
•
•
Publication
37118504 | J:337860
First Author: Dejanovic B
Year: 2022
Journal: Nat Aging
Title: Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Volume: 2
Issue: 9
Pages: 837-850
•
•
•
•
•
Publication
39172838 | J:362866
First Author: Minhas PS
Year: 2024
Journal: Science
Title: Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Volume: 385
Issue: 6711
Pages: eabm6131
•
•
•
•
•
Publication
41833151 | J:387163
 
First Author: Aguado C
Year: 2026
Journal: Tissue Cell
Title: Amyloid-?? and tau pathology induce a reduction of the G-protein G??(o) subunit in the mouse hippocampus.
Volume: 101
Pages: 103436
•
•
•
•
•
Publication
38658772 | J:368207
First Author: Qian Z
Year: 2024
Journal: Mol Psychiatry
Title: Thy1-ApoE4/C/EBP? double transgenic mice act as a sporadic model with Alzheimer's disease.
Volume: 29
Issue: 10
Pages: 3040-3055
•
•
•
•
•
Publication
38967283 | J:386918
First Author: Damuka N
Year: 2024
Journal: Alzheimers Dement
Title: Exploring microtubule dynamics in Alzheimer's disease: Longitudinal assessment using [(11)C]MPC-6827 PET imaging in rodent models of Alzheimer's-related pathology.
Volume: 20
Issue: 9
Pages: 6082-6093
•
•
•
•
•
Publication
30879788 | J:352674
First Author: Martorell AJ
Year: 2019
Journal: Cell
Title: Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition.
Volume: 177
Issue: 2
Pages: 256-271.e22
•
•
•
•
•
Publication
36912451 | J:348477
 
First Author: Sai K
Year: 2023
Journal: J Cell Sci
Title: Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models.
Volume: 136
Issue: 6
•
•
•
•
•
Publication
41235867 | J:375418
First Author: Ladurner G
Year: 2025
Journal: Invest Ophthalmol Vis Sci
Title: Comparative Investigation of the Retinal Phenotype of Three Mouse Models of Alzheimer's Disease With Optical Coherence Tomography.
Volume: 66
Issue: 14
Pages: 35
•
•
•
•
•
Publication
41295893 | J:379851
First Author: Aguado C
Year: 2026
Journal: J Alzheimers Dis
Title: Disruption of Ca(V)2.3 channels in the brain of the 5xFAD mice.
Volume: 109
Issue: 2
Pages: 699-717
•
•
•
•
•
Genotype
Genotype
Symbol: Cx3cr1/Cx3cr1 Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cx3cr1/Cx3cr1<+> Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
34385305 | J:309543
 
First Author: Wang H
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol.
Volume: 118
Issue: 33
•
•
•
•
•
Publication
37143894 | J:337547
 
First Author: Tiberi A
Year: 2023
Journal: Front Cell Dev Biol
Title: Reduced levels of NGF shift astrocytes toward a neurotoxic phenotype.
Volume: 11
Pages: 1165125
•
•
•
•
•
Publication
21925604 | J:189488
First Author: Waite MR
Year: 2012
Journal: Mol Cell Neurosci
Title: Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2.
Volume: 49
Issue: 1
Pages: 32-43
•
•
•
•
•
Publication
37557174 | J:339867
First Author: Prigge CL
Year: 2023
Journal: Dev Cell
Title: Rejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling.
Volume: 58
Issue: 20
Pages: 2080-2096.e7
•
•
•
•
•
Publication
34505007 | J:313520
First Author: Aguilar-Pineda JA
Year: 2021
Journal: iScience
Title: Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease.
Volume: 24
Issue: 9
Pages: 102993
•
•
•
•
•
Publication
33846335 | J:311263
First Author: Kim K
Year: 2021
Journal: Nat Commun
Title: Therapeutic B-cell depletion reverses progression of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 2185
•
•
•
•
•
Publication
25331900 | J:216662
First Author: Chow HM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CDK5 activator protein p25 preferentially binds and activates GSK3?.
Volume: 111
Issue: 45
Pages: E4887-95
•
•
•
•
•
Publication
25002035 | J:218071
First Author: Orre M
Year: 2014
Journal: Neurobiol Aging
Title: Isolation of glia from Alzheimer's mice reveals inflammation and?dysfunction.
Volume: 35
Issue: 12
Pages: 2746-2760
•
•
•
•
•
Publication
33663578 | J:311283
First Author: Chen M
Year: 2021
Journal: Mol Neurodegener
Title: Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models.
Volume: 16
Issue: 1
Pages: 14
•
•
•
•
•
Publication
38502413 | J:350687
First Author: Kong Y
Year: 2024
Journal: Mol Neurobiol
Title: Relationship Between Reactive Astrocytes, by [(18)F]SMBT-1 Imaging, with Amyloid-Beta, Tau, Glucose Metabolism, and TSPO in Mouse Models of Alzheimer's Disease.
Volume: 61
Issue: 10
Pages: 8387-8401
•
•
•
•
•
Publication
33955647 | J:311343
First Author: Wu L
Year: 2021
Journal: Aging Cell
Title: Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13371
•
•
•
•
•
Publication
27752775 | J:311368
First Author: Jan A
Year: 2017
Journal: Acta Neuropathol
Title: eEF2K inhibition blocks A?42 neurotoxicity by promoting an NRF2 antioxidant response.
Volume: 133
Issue: 1
Pages: 101-119
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom