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Search results 3001 to 3100 out of 4141 for Mtor

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Hits by Pathway

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Female
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890263
Specimen Label: MRC Harwell_890263
Detected: false
Specimen Num: 12
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890265
Specimen Label: MRC Harwell_890265
Detected: true
Specimen Num: 13
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•
GXD Expression
GXD Expression
 
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945124
Age: postnatal day 7
Image: g00580 P7
Specimen Label: g00580 P7
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890271
Specimen Label: MRC Harwell_890271
Detected: true
Specimen Num: 16
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•
GXD Expression
GXD Expression
 
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945124
Age: embryonic day 11.5
Image: g00580 E11.5
Specimen Label: g00580 E11.5
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945124
Age: postnatal day 7
Image: g00580 P7
Specimen Label: g00580 P7
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945124
Age: postnatal day 7
Image: g00580 P7
Specimen Label: g00580 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890261
Specimen Label: MRC Harwell_890261
Detected: true
Specimen Num: 11
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945124
Age: embryonic day 15.5
Image: g00580 E15.5
Specimen Label: g00580 E15.5
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945124
Age: postnatal day 7
Image: g00580 P7
Note: Expression was region specific and scattered.
Specimen Label: g00580 P7
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890245
Specimen Label: MRC Harwell_890245
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890269
Specimen Label: MRC Harwell_890269
Detected: true
Specimen Num: 15
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945124
Age: embryonic day 15.5
Image: g00580 E15.5
Specimen Label: g00580 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890253
Specimen Label: MRC Harwell_890253
Detected: true
Specimen Num: 7
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945124
Age: embryonic day 15.5
Image: g00580 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00580 E15.5
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884775
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945124
Age: postnatal day 7
Image: g00580 P7
Specimen Label: g00580 P7
Detected: true
Specimen Num: 3
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•
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890267
Specimen Label: MRC Harwell_890267
Detected: true
Specimen Num: 14
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890241
Specimen Label: MRC Harwell_890241
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890247
Specimen Label: MRC Harwell_890247
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:6182568
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189698
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - 4932417H02Rik
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6182568
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189698
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - 4932417H02Rik
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:6182568
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189698
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - 4932417H02Rik
Detected: true
Specimen Num: 3
•
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6182568
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189698
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - 4932417H02Rik
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:6182568
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189698
Age: postnatal day 4
Specimen Label: Table S2 - P4 - 4932417H02Rik
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Probe: MGI:6182568
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189698
Age: postnatal day 14
Specimen Label: Table S2 - P14 - 4932417H02Rik
Detected: true
Specimen Num: 6
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6182568
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189698
Age: postnatal day 28
Specimen Label: Table S2 - P28 - 4932417H02Rik
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890243
Specimen Label: MRC Harwell_890243
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890249
Specimen Label: MRC Harwell_890249
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890251
Specimen Label: MRC Harwell_890251
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692091
Age: postnatal adult
Image: MRC Harwell_890247
Specimen Label: MRC Harwell_890247
Detected: true
Specimen Num: 4
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Publication
30988188 | J:274662
First Author: Cho SH
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia-inducible factors in CD4+ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.
Volume: 116
Issue: 18
Pages: 8975-8984
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Publication
28679588 | J:245956
First Author: Chimin P
Year: 2017
Journal: J Lipid Res
Title: Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.
Volume: 58
Issue: 9
Pages: 1797-1807
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Publication
12606363 | J:83525
First Author: Brown PR
Year: 2003
Journal: Biol Reprod
Title: A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.
Volume: 68
Issue: 6
Pages: 2241-8
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Protein
A7MAY7
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: false
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Publication
15450605 | -
First Author: Ginalski K
Year: 2004
Journal: Trends Biochem Sci
Title: Raptor protein contains a caspase-like domain.
Volume: 29
Issue: 10
Pages: 522-4
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Protein
Q570Y9
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: false
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Protein
B2ZRS5
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: false
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Protein
B2ZRS6
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: false
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Protein
B2ZRS3
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: false
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Publication
- | J:165963
     
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
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Publication
24315998 | J:209300
First Author: Yang K
Year: 2013
Journal: Immunity
Title: T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.
Volume: 39
Issue: 6
Pages: 1043-56
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Publication
35377454 | J:326872
First Author: Monteiro LB
Year: 2022
Journal: Diabetes
Title: Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity.
Volume: 71
Issue: 7
Pages: 1546-1561
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Publication
29809146 | J:264200
   
First Author: Yang C
Year: 2018
Journal: Elife
Title: mTORC1 and mTORC2 differentially promote natural killer cell development.
Volume: 7
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Publication
29164996 | J:257335
   
First Author: Mishra SK
Year: 2018
Journal: Autophagy
Title: CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation.
Pages: 1-18
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Publication
17273556 | J:118038
First Author: Le Bacquer O
Year: 2007
Journal: J Clin Invest
Title: Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.
Volume: 117
Issue: 2
Pages: 387-96
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Publication
16710422 | J:109025
First Author: Kim S
Year: 2006
Journal: Nature
Title: A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.
Volume: 441
Issue: 7091
Pages: 362-5
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Publication
18487439 | J:138207
First Author: Essop MF
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice.
Volume: 295
Issue: 1
Pages: H256-65
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Publication
27951586 | J:240431
     
First Author: Karki R
Year: 2016
Journal: Nature
Title: NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.
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Publication
18974783 | J:143922
First Author: Chen J
Year: 2008
Journal: PLoS One
Title: Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Volume: 3
Issue: 10
Pages: e3581
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Publication
22709692 | J:189078
First Author: Baba M
Year: 2012
Journal: Blood
Title: The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
Volume: 120
Issue: 6
Pages: 1254-61
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Publication
29897930 | J:262829
First Author: Centini R
Year: 2018
Journal: PLoS One
Title: Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.
Volume: 13
Issue: 6
Pages: e0197973
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Publication
27378698 | J:237861
First Author: Magalhaes J
Year: 2016
Journal: Hum Mol Genet
Title: Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease.
Volume: 25
Issue: 16
Pages: 3432-3445
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Publication
15705789 | J:98472
First Author: Hammerman PS
Year: 2005
Journal: Blood
Title: Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.
Volume: 105
Issue: 11
Pages: 4477-83
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Publication
17476689 | J:153319
First Author: Bohensky J
Year: 2007
Journal: J Cell Physiol
Title: PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.
Volume: 213
Issue: 1
Pages: 246-51
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Publication
23695157 | J:201107
First Author: Al-Qusairi L
Year: 2013
Journal: FASEB J
Title: Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.
Volume: 27
Issue: 8
Pages: 3384-94
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Publication
18347057 | J:136089
First Author: Bayascas JR
Year: 2008
Journal: Mol Cell Biol
Title: Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Volume: 28
Issue: 10
Pages: 3258-72
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Publication
25139996 | J:216403
First Author: Nikonova AS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Nedd9 restrains renal cystogenesis in Pkd1-/- mice.
Volume: 111
Issue: 35
Pages: 12859-64
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Publication
29288408 | J:272348
First Author: Wu W
Year: 2018
Journal: J Physiol Biochem
Title: Muscle-specific deletion of Prkaa1 enhances skeletal muscle lipid accumulation in mice fed a high-fat diet.
Volume: 74
Issue: 2
Pages: 195-205
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Publication
18057094 | J:132294
First Author: Ropelle ER
Year: 2008
Journal: Diabetes
Title: A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss.
Volume: 57
Issue: 3
Pages: 594-605
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Publication
26042865 | J:258701
First Author: Kanamori H
Year: 2015
Journal: Autophagy
Title: Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes.
Volume: 11
Issue: 7
Pages: 1146-60
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Publication
22311416 | J:182524
First Author: Kim DK
Year: 2012
Journal: Diabetologia
Title: Translationally controlled tumour protein is associated with podocyte hypertrophy in a mouse model of type 1 diabetes.
Volume: 55
Issue: 4
Pages: 1205-17
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Publication
38424194 | J:347622
First Author: Yang S
Year: 2024
Journal: Exp Mol Med
Title: Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop.
Volume: 56
Issue: 3
Pages: 630-645
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Publication
31040190 | J:292962
First Author: Sakai S
Year: 2019
Journal: J Am Soc Nephrol
Title: Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes.
Volume: 30
Issue: 6
Pages: 929-945
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Publication
24101677 | J:209030
First Author: Guzman J
Year: 2014
Journal: Diabetes
Title: Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.
Volume: 63
Issue: 2
Pages: 701-14
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Publication
25094045 | J:220115
First Author: Arumugam A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch.
Volume: 451
Issue: 3
Pages: 394-401
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Publication
37048066 | J:334730
 
First Author: Lin DS
Year: 2023
Journal: Cells
Title: Rapamycin Alleviates Protein Aggregates, Reduces Neuroinflammation, and Rescues Demyelination in Globoid Cell Leukodystrophy.
Volume: 12
Issue: 7
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Publication
20624962 | J:162570
First Author: Ranieri SC
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance.
Volume: 107
Issue: 30
Pages: 13420-5
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Publication
23832089 | J:199992
First Author: Pajvani UB
Year: 2013
Journal: Nat Med
Title: Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.
Volume: 19
Issue: 8
Pages: 1054-60
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Publication
22466652 | J:184540
First Author: Ai D
Year: 2012
Journal: J Clin Invest
Title: Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.
Volume: 122
Issue: 5
Pages: 1677-87
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Publication
28987875 | J:257340
 
First Author: Pires KM
Year: 2017
Journal: J Mol Cell Cardiol
Title: Activation of IGF-1 receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice.
Volume: 113
Pages: 39-50
•
•
•
•
•
Publication
22451924 | J:183540
First Author: Serebrennikova OB
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation.
Volume: 109
Issue: 18
Pages: E1082-91
•
•
•
•
•
Publication
23531613 | J:198215
First Author: White JP
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK.
Volume: 304
Issue: 10
Pages: E1042-52
•
•
•
•
•
Publication
26378024 | J:291741
First Author: Chang J
Year: 2015
Journal: Oncotarget
Title: Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis.
Volume: 6
Issue: 32
Pages: 33500-11
•
•
•
•
•
Publication
31018249 | J:349068
First Author: Khan N
Year: 2019
Journal: Int J Cancer
Title: Fisetin and 5-fluorouracil: Effective combination for PIK3CA-mutant colorectal cancer.
Volume: 145
Issue: 11
Pages: 3022-3032
•
•
•
•
•
Publication
22581840 | J:190770
First Author: Kumar A
Year: 2012
Journal: Carcinogenesis
Title: Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer.
Volume: 33
Issue: 9
Pages: 1726-35
•
•
•
•
•
Publication
26839262 | J:235544
First Author: Ghaleb AM
Year: 2016
Journal: Mol Cancer Res
Title: KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Volume: 14
Issue: 4
Pages: 385-96
•
•
•
•
•
Publication
19966863 | J:160401
First Author: Koehl GE
Year: 2010
Journal: Oncogene
Title: Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APC(Min/+) mice.
Volume: 29
Issue: 10
Pages: 1553-60
•
•
•
•
•
Publication
20663899 | J:162767
First Author: Metcalfe C
Year: 2010
Journal: Cancer Res
Title: Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.
Volume: 70
Issue: 16
Pages: 6629-38
•
•
•
•
•
Publication
23741059 | J:205456
First Author: Jiang L
Year: 2013
Journal: Mol Cancer Res
Title: Epithelial-specific deletion of 11β-HSD2 hinders Apcmin/+ mouse tumorigenesis.
Volume: 11
Issue: 9
Pages: 1040-50
•
•
•
•
•
Publication
32219372 | J:297758
First Author: Sikder MOF
Year: 2020
Journal: Biochem J
Title: SLC6A14, a Na+/Cl--coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling.
Volume: 477
Issue: 8
Pages: 1409-1425
•
•
•
•
•
Publication
28549178 | J:243648
First Author: Mu X
Year: 2017
Journal: Hum Mol Genet
Title: RhoA/ROCK inhibition improves the beneficial effects of glucocorticoid treatment in dystrophic muscle: implications for stem cell depletion.
Volume: 26
Issue: 15
Pages: 2813-2824
•
•
•
•
•
Publication
25054970 | J:219008
First Author: Sharma P
Year: 2014
Journal: PLoS One
Title: Role of dystrophin in airway smooth muscle phenotype, contraction and lung function.
Volume: 9
Issue: 7
Pages: e102737
•
•
•
•
•
Publication
21216283 | J:170661
First Author: Boppart MD
Year: 2011
Journal: Biochim Biophys Acta
Title: Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy.
Volume: 1812
Issue: 4
Pages: 439-46
•
•
•
•
•
Publication
29717938 | J:280706
First Author: Kipp KR
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease.
Volume: 315
Issue: 2
Pages: F395-F405
•
•
•
•
•
Publication
19330036 | J:147455
First Author: Granville CA
Year: 2009
Journal: PLoS One
Title: A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.
Volume: 4
Issue: 3
Pages: e5061
•
•
•
•
•
Publication
24614103 | J:209612
First Author: Wu J
Year: 2014
Journal: J Clin Invest
Title: iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
Volume: 124
Issue: 4
Pages: 1685-98
•
•
•
•
•
Publication
27737881 | J:238434
First Author: Liu Y
Year: 2017
Journal: Cancer Res
Title: Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment.
Volume: 77
Issue: 2
Pages: 520-531
•
•
•
•
•
Publication
18164202 | J:144615
First Author: Johannessen CM
Year: 2008
Journal: Curr Biol
Title: TORC1 is essential for NF1-associated malignancies.
Volume: 18
Issue: 1
Pages: 56-62
•
•
•
•
•
Publication
27889578 | J:238268
 
First Author: Switon K
Year: 2017
Journal: Neuroscience
Title: Molecular neurobiology of mTOR.
Volume: 341
Pages: 112-153
•
•
•
•
•
Publication
16885364 | J:112099
First Author: Wendel HG
Year: 2006
Journal: Cancer Res
Title: Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo.
Volume: 66
Issue: 15
Pages: 7639-46
•
•
•
•
•
Publication
18443001 | J:136907
First Author: Mariño G
Year: 2008
Journal: Hum Mol Genet
Title: Premature aging in mice activates a systemic metabolic response involving autophagy induction.
Volume: 17
Issue: 14
Pages: 2196-211
•
•
•
•
•
Publication
37142882 | J:355083
First Author: Xu J
Year: 2023
Journal: Adv Sci (Weinh)
Title: KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition.
Volume: 10
Issue: 19
Pages: e2206098
•
•
•
•
•
Publication
22135462 | J:180528
First Author: Hettmer S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells.
Volume: 108
Issue: 50
Pages: 20002-7
•
•
•
•
•
Publication
20072130 | J:162611
First Author: Janes MR
Year: 2010
Journal: Nat Med
Title: Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Volume: 16
Issue: 2
Pages: 205-13
•
•
•
•
•
Publication
34974060 | J:324578
 
First Author: Ye Z
Year: 2022
Journal: J Mol Cell Cardiol
Title: GALNT4 primes monocytes adhesion and transmigration by regulating O-Glycosylation of PSGL-1 in atherosclerosis.
Volume: 165
Pages: 54-63
•
•
•
•
•
Publication
33140520 | J:301542
   
First Author: Hamid SM
Year: 2020
Journal: EMBO Rep
Title: Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth.
Pages: e51462
•
•
•
•
•
Publication
25210801 | J:317657
 
First Author: So EY
Year: 2014
Journal: Cell Death Dis
Title: Translational initiation regulated by ATM in dendritic cells development.
Volume: 5
Pages: e1418
•
•
•
•
•
Publication
30622306 | J:295469
First Author: He J
Year: 2019
Journal: Cell Death Differ
Title: Stage-specific requirement of kinase PDK1 for NK cells development and activation.
Volume: 26
Issue: 10
Pages: 1918-1928
•
•
•
•
•
Publication
27642729 | J:241320
First Author: Kaneda MM
Year: 2016
Journal: Nature
Title: PI3Kγ is a molecular switch that controls immune suppression.
Volume: 539
Issue: 7629
Pages: 437-442
•
•
•
•
•
Publication
32690871 | J:354238
First Author: Wang X
Year: 2021
Journal: Mucosal Immunol
Title: A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice.
Volume: 14
Issue: 2
Pages: 342-356
•
•
•
•
•




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